CN104094937B - A kind of containing fluorine bacterium azoles and the bactericidal composition of CGA-173506 - Google Patents

Abstract

The present invention relates to a kind of bactericidal composition, its effective ingredient includes fluorine bacterium azoles and CGA-173506.It is mainly used in preventing and treating Xiao Ming's powdery mildew, is shown by indoor antibacterial test and field test, when fluorine bacterium azoles and CGA-173506 compound with the ratio of 1:10 10:1, there is potentiation, the purpose that preferable disease pest is ruled can be reached, reduce times for spraying, be effectively saved labor cost.The bactericidal composition of the present invention can be processed into water dispersible granules, suspending agent.

Description

A kind of containing fluorine bacterium azoles and the bactericidal composition of CGA-173506

Technical field

The present invention relates to a kind of disinfectant use in agriculture, effective ingredient includes fluorine bacterium azoles, CGA-173506, it is adaptable to prevent and treat little Wheat powdery mildew.

Technical background

Fluorine bacterium azoles be a kind of have concurrently protection, treatment and the interior absorption triazole bactericidal agent of eradicant action, be sterol Demethylation inhibitors, by tissue resorption such as root of the crop, stem, leaves, and upwards can conduct, through toxicity Measure and field control effectiveness test result shows there is preferable prevention effect to fruit white rot of grape.

The mechanism of action of CGA-173506 is the activity of the histidine kinase affecting osmotic pressure regulation signal correction, preventing and treating The black powder of the bunt of wheat, snow mold, snow mold, banded sclerotial blight, root rot, full rot, glume blight, stalk Sick；Stripe disease of barley, net blotch, covered smut, snow mold；Corn Stalk Rot, base rot disease, damping off Sick；Cotton seedling blight, red rot, anthrax, black root, seed rot；Soybean peanut damping-off, Root rot.

Wheat powdery mildew is a kind of worldwide disease, all has a distribution in each main wheat producing countries, China's Shandong coastal waters, Sichuan, Guizhou, Yunnan occur universal, cause harm and also weigh.In recent years this disease northeastward, North China, northwest Mai Qu, Also there is the gesture being on the rise.This disease can encroach on each organ of wheat plant overground part, but based on blade and sheath, During morbidity weight, grain husk shell and awns also can be injured.When just falling ill, blade face occur 1～2mm white mildew, after gradually Expanding as subcircular the most oval white mildew, there is one layer of white lead on mildew surface, meets external force or vibrates immediately Disperse.These powders are exactly mycelium and the conidium of this bacterium.The mould layer in later stage disease portion becomes canescence extremely Light brown, scattered on scab have pinhead-sized little black grain point, the i.e. cleistothecium of pathogen.

In actual survey is studied, it has been found that fluorine bacterium azoles, CGA-173506 are compounded, to wheat powdery mildew Having obviously potentiation, according to long-term tracking test, this complex agent type, in actual application In be difficult to produce resistance, and in use, consumption is the lowest, and the negative effect to environment is the least.

Summary of the invention

It is an object of the invention to provide a kind of bactericidal composition for preventing and treating wheat powdery mildew.

It is an object of the invention to be achieved through the following technical solutions:

A kind of containing fluorine bacterium azoles and the bactericidal composition of CGA-173506, its effective ingredient includes fluorine bacterium azoles and CGA-173506, The mass fraction of fluorine bacterium azoles and CGA-173506 ratio is for 1:10-10:1, and remaining is for allowing in pesticide to use and can connect The auxiliary element being subject to.

Described auxiliary element is solvent, emulsifying agent, wetting agent, dispersant, stabilizer, antifreezing agent, increasing One or more in thick dose, disintegrating agent, defoamer, penetrating agent, synergist, preservative and filler Combination, above material is in pesticidal preparations conventional known substance, according to being prepared as different pesticide agents Type and be varied from, but be not particularly limited.

Bactericidal composition of the present invention can with known method can be prepared as being suitable for using in agricultural production any A kind of dosage form, reasonable dosage form has water dispersible granules, suspending agent.

The frequency of administration of compounded preparation of pesticide of the present invention and amount of application are with crops, insect, weather condition change And have small variations, can reach, by using suitable dosage, the purpose effectively prevented and treated.

Compared with prior art, it is an advantage of the current invention that:

1, the present invention has obvious synergistic function, is used alone than single dose and improves prevention effect.

2, dual function mechanism, delays the generation of disease drug resistance.

3, two kinds of effective ingredient compound, and reduce Pesticide use amount, reduce use cost and the dirt to environment Dye.

Detailed description of the invention

In order to be more fully understood that the essence of the present invention, below in conjunction with embodiment, present disclosure is made further Illustrate, but limitation of the present invention can not be considered as.

Embodiment 1: toxicity determination test (wheat powdery mildew indoor colony growth inhibition test).

Test method is carried out with reference to Wu Wenjun " chemical protection of plant experimental technique introduction " (1993).By 95% Fluorine bacterium azoles, 95.4% CGA-173506 former medicine folding hundred after make 9.6 μ g/mL mother solutions with acetone, tween 80 respectively, Utilizing mother liquor to become CGA-173506, fluorine bacterium azoles mass ratio to be respectively 1:10 10:1, gradient is respectively 0.6 μ g/mL, 1.2 μ g/mL, 2.4 μ g/mL, the medicinal liquid of 4.8 μ g/mL carry out field spray test.Examination Test the concrete data of result such as table 1.

Table 1, CGA-173506 and the indoor antibacterial test data of fluorine bacterium azoles combination.

Calculate toxicity index and the co-toxicity coefficient (CTC value) of mixture of each medicament according to the abundant method of Sun Yun, work as CTC ≤ 80 is antagonism, and 80 CTC 120 are summation action, and CTC >=120 are potentiation.

Being found by indoor bacterium colony Developing restraint test, CGA-173506, fluorine bacterium azoles are according to the ratio of 1:10 10:1 After Fu Pei, wheat powdery mildew is born and long be respectively provided with potentiation or be added inhibitory action, wherein fluorine bacterium azoles, cough up Bacterium nitrile is the most obvious with 1:1 potentiation, and co-toxicity coefficient is 147.82, and the two compound synergic is notable, it is possible to more Add the effective extension suppressing bacterium colony.

According to indoor preparation research, bactericidal composition of the present invention can be processed into water dispersible granules, suspending agent uses.

Embodiment 2: prepare 24% fluorine bacterium azoles CGA-173506 suspending agent.

Weigh 12% fluorine bacterium azoles, 12% CGA-173506,2% agriculture breast 602,4% agriculture breast 2201,3% lignosulfonates, 0.2% xanthan gum, 4% ethylene glycol, 0.5% organic silicon defoamer, add deionized water and mend to 100%.By above-mentioned former After material mixing, prepare 24% fluorine bacterium azoles CGA-173506 suspending agent through high speed shear emulsifying.

Embodiment 3: prepare 50% fluorine bacterium azoles CGA-173506 water dispersible granules.

Weigh 25% fluorine bacterium azoles, 25% CGA-173506,4% sodium lauryl sulphate, 12% sodium lignin sulfonate, 6% Naphthalene sulfonate, 1.2% disintegrating agent, bentonite complement to 100%.After above-mentioned raw materials is mixed, through air-flow powder Broken machine pulverizing pelletize, prepares 50% fluorine bacterium azoles CGA-173506 water dispersible granules.

Embodiment 4: fluorine bacterium azoles and the field control effectiveness test of CGA-173506 mixture composition for preventing and controlling wheat powdery mildew.

Reagent agent and dispenser dosage:

(1) 24% fluorine bacterium azoles CGA-173506 suspending agent (effective ingredient mass ratio: 1:1), 120 grams of preparation of mu

(2) 50% fluorine bacterium azoles CGA-173506 water dispersible granules (effective ingredient mass ratio: 1:1), 60 grams of preparation of mu Comparison medicament and dispenser dosage:

(3) 20% triflumizole wettable powders, 25 grams of preparation of mu.

(4) 80% CGA-173506 wettable powders, 30 grams of preparation of mu.

Spraying time and application method: wheat powdery mildew their early stage dispenser, be watered even spraying.

Table 2, the field control effectiveness test result of preventing and treating wheat powdery mildew.

Result of the test: be shown in Table 2, as can be seen from the test results: after dispenser 7 days, the fluorine bacterium azoles of the present invention with CGA-173506 mixture compositions to wheat powdery mildew preventive effect all more than 70%, hence it is evident that be better than the single dose of comparison；Dispenser Latter 14 days, the fluorine bacterium azoles of the present invention and CGA-173506 mixture compositions to wheat powdery mildew preventive effect all more than 80%, Also significantly better than the single dose of comparison；In process of the test, each medicament is showed no poisoning generation, to crop safety.Say The fluorine bacterium azoles of the bright present invention and CGA-173506 mixture compositions are better than single dose, improve actual prevention effect, reduce and use Dose, reduces cost, reduces the medicament adverse effect to environment, delays the generation of disease drug resistance, to agriculture Industry comprehensive control has great significance.

Claims (2)

1. one kind contains fluorine bacterium azoles and the bactericidal composition of CGA-173506, it is characterised in that: its effective ingredient includes fluorine bacterium azoles and CGA-173506, and the mass fraction of fluorine bacterium azoles and CGA-173506 ratio is for 1:10,1:5 or 1:1.

2. the purposes in preventing and treating wheat powdery mildew of a kind of bactericidal composition containing fluorine bacterium azoles and CGA-173506 described in claim 1.