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ATE459341T1 - Nanoteilchenförmige imatinib-mesylat- formulierungen - Google Patents

Nanoteilchenförmige imatinib-mesylat- formulierungen

Info

Publication number
ATE459341T1
ATE459341T1 AT06772091T AT06772091T ATE459341T1 AT E459341 T1 ATE459341 T1 AT E459341T1 AT 06772091 T AT06772091 T AT 06772091T AT 06772091 T AT06772091 T AT 06772091T AT E459341 T1 ATE459341 T1 AT E459341T1
Authority
AT
Austria
Prior art keywords
imatinib mesylate
nanoparticle
shaped
mesylate formulations
nanoparticulate
Prior art date
Application number
AT06772091T
Other languages
English (en)
Inventor
Scott Jenkins
Gary Liversidge
Original Assignee
Elan Pharma Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharma Int Ltd filed Critical Elan Pharma Int Ltd
Application granted granted Critical
Publication of ATE459341T1 publication Critical patent/ATE459341T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06772091T 2005-06-03 2006-06-05 Nanoteilchenförmige imatinib-mesylat- formulierungen ATE459341T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68714605P 2005-06-03 2005-06-03
PCT/US2006/021657 WO2006133046A2 (en) 2005-06-03 2006-06-05 Nanoparticulate imatinib mesylate formulations

Publications (1)

Publication Number Publication Date
ATE459341T1 true ATE459341T1 (de) 2010-03-15

Family

ID=37498974

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06772091T ATE459341T1 (de) 2005-06-03 2006-06-05 Nanoteilchenförmige imatinib-mesylat- formulierungen

Country Status (18)

Country Link
US (1) US20060275372A1 (de)
EP (1) EP1895984B8 (de)
JP (1) JP2008542397A (de)
KR (1) KR20080017067A (de)
CN (1) CN101232870A (de)
AT (1) ATE459341T1 (de)
AU (1) AU2006255177A1 (de)
BR (1) BRPI0613540A2 (de)
CA (1) CA2610448A1 (de)
DE (1) DE602006012671D1 (de)
EA (2) EA201100022A1 (de)
ES (1) ES2341996T3 (de)
HK (1) HK1118467A1 (de)
IL (1) IL187841A0 (de)
MX (1) MX2007015309A (de)
NO (1) NO20076691L (de)
WO (1) WO2006133046A2 (de)
ZA (1) ZA200710763B (de)

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CN104739785A (zh) * 2013-12-25 2015-07-01 辰欣药业股份有限公司 一种具高溶出行为的甲磺酸伊马替尼片的组成及制备方法
CN106856249B (zh) * 2016-12-19 2019-07-09 河南超威电源有限公司 一种以阿拉伯胶作为稳定剂制备胶体电解液的方法
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CN108904809A (zh) * 2018-08-20 2018-11-30 黎庆有 一种靶向抗肿瘤药物
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BRPI0613540A2 (pt) 2011-01-18
EP1895984B1 (de) 2010-03-03
EA015102B1 (ru) 2011-06-30
US20060275372A1 (en) 2006-12-07
WO2006133046A2 (en) 2006-12-14
DE602006012671D1 (de) 2010-04-15
JP2008542397A (ja) 2008-11-27
NO20076691L (no) 2008-02-25
EP1895984B8 (de) 2010-05-12
MX2007015309A (es) 2008-03-05
CN101232870A (zh) 2008-07-30
KR20080017067A (ko) 2008-02-25
IL187841A0 (en) 2008-03-20
EA201100022A1 (ru) 2011-06-30
WO2006133046A3 (en) 2007-07-26
ES2341996T3 (es) 2010-06-30
EP1895984A2 (de) 2008-03-12
AU2006255177A1 (en) 2006-12-14
HK1118467A1 (en) 2009-02-13
ZA200710763B (en) 2009-09-30
CA2610448A1 (en) 2006-12-14

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