Nothing Special   »   [go: up one dir, main page]

ATE157987T1 - Teilweise modifizierte und retro-invertierte tetrapeptides analogue von fragmenten des c reaktiven proteins - Google Patents

Teilweise modifizierte und retro-invertierte tetrapeptides analogue von fragmenten des c reaktiven proteins

Info

Publication number
ATE157987T1
ATE157987T1 AT93908898T AT93908898T ATE157987T1 AT E157987 T1 ATE157987 T1 AT E157987T1 AT 93908898 T AT93908898 T AT 93908898T AT 93908898 T AT93908898 T AT 93908898T AT E157987 T1 ATE157987 T1 AT E157987T1
Authority
AT
Austria
Prior art keywords
pct
chain
retro
inverted
fragments
Prior art date
Application number
AT93908898T
Other languages
English (en)
Inventor
Antonio Silvio Verdini
Massimo Pinori
Silvana Cappelletti
Laura Gazerro
Flavio Leoni
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Application granted granted Critical
Publication of ATE157987T1 publication Critical patent/ATE157987T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93908898T 1992-04-16 1993-04-02 Teilweise modifizierte und retro-invertierte tetrapeptides analogue von fragmenten des c reaktiven proteins ATE157987T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920939A IT1254883B (it) 1992-04-16 1992-04-16 Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Publications (1)

Publication Number Publication Date
ATE157987T1 true ATE157987T1 (de) 1997-09-15

Family

ID=11362983

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93908898T ATE157987T1 (de) 1992-04-16 1993-04-02 Teilweise modifizierte und retro-invertierte tetrapeptides analogue von fragmenten des c reaktiven proteins

Country Status (18)

Country Link
US (2) US5521159A (de)
EP (1) EP0636140B1 (de)
JP (1) JP3036844B2 (de)
KR (1) KR100255526B1 (de)
CN (1) CN1039124C (de)
AT (1) ATE157987T1 (de)
AU (1) AU667096B2 (de)
CA (1) CA2118136C (de)
DE (1) DE69313842T2 (de)
ES (1) ES2109487T3 (de)
FI (1) FI944224A0 (de)
HU (1) HUT70179A (de)
IT (1) IT1254883B (de)
NO (1) NO943903L (de)
NZ (1) NZ251697A (de)
TW (1) TW242145B (de)
WO (1) WO1993021208A1 (de)
ZA (1) ZA932614B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254883B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.
IT1271486B (it) * 1993-10-12 1997-05-28 Italfarmaco Spa Oligopeptidi immunomodulatori derivati di frammenti della proteina c- reattiva
HUP0105437A3 (en) 1999-01-02 2003-03-28 Aventis Pharma Gmbh Novel malonic acid derivatives, processes for their preparation, their use and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253190B1 (de) * 1986-07-16 1992-12-30 ENIRICERCHE S.p.A. Teilweise retro-invertierte Analoge des Tuftsin, Methode zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
IT1254883B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Tetrapeptidi parzialmente modificati e retroinvertiti, analoghi di frammenti della proteina c-reattiva.

Also Published As

Publication number Publication date
ITMI920939A0 (it) 1992-04-16
US5578575A (en) 1996-11-26
NZ251697A (en) 1995-10-26
HU9402952D0 (en) 1995-02-28
IT1254883B (it) 1995-10-11
ITMI920939A1 (it) 1993-10-16
CN1078476A (zh) 1993-11-17
NO943903L (no) 1994-12-15
US5521159A (en) 1996-05-28
ZA932614B (en) 1993-10-26
AU667096B2 (en) 1996-03-07
DE69313842T2 (de) 1998-04-09
CN1039124C (zh) 1998-07-15
JPH07505640A (ja) 1995-06-22
DE69313842D1 (de) 1997-10-16
FI944224A (fi) 1994-09-13
EP0636140B1 (de) 1997-09-10
EP0636140A1 (de) 1995-02-01
HUT70179A (en) 1995-09-28
ES2109487T3 (es) 1998-01-16
CA2118136A1 (en) 1993-10-28
AU3951493A (en) 1993-11-18
FI944224A0 (fi) 1994-09-13
WO1993021208A1 (en) 1993-10-28
JP3036844B2 (ja) 2000-04-24
NO943903D0 (no) 1994-10-14
KR100255526B1 (ko) 2000-05-01
TW242145B (de) 1995-03-01
CA2118136C (en) 2002-03-26

Similar Documents

Publication Publication Date Title
NO911787D0 (no) Peptidaminer samt fremgangsmaate for fremstilling derav.
SE9100342D0 (sv) Novel steroid esters
MX9202287A (es) Nuevos derivados de perhidroisoindol, procedimiento para su preparacion y composicion farmaceutica que los contiene.
DE69532754D1 (de) Faktor xa inhibitoren
ATE86964T1 (de) Malonsaeurederivate und ihre synthesemethoden.
TR199901128T2 (xx) N-(aril/heteroarilasetil) amino asit esterler, bunu ihtiva eden farmas�tik bile�imler ve bu t�r bile�ikler kullanarak �-amiloit peptit sal�n�m�n� ve/veya bunun sentezlenmesini inhibe etme y�ntemleri.
DE69317772D1 (de) Peptidderivate des Carboxy-Terminalen Sequenz von Hirudin
ATE63126T1 (de) Tetra- und penta-peptide mit der sequenz lysylarginyl-aspartyl, und ihre verwendung als antithrombotika.
ATE157987T1 (de) Teilweise modifizierte und retro-invertierte tetrapeptides analogue von fragmenten des c reaktiven proteins
ATE149518T1 (de) Hexapeptide
DE69013742D1 (de) Peptide und diese Peptide enthaltende Wirkstoffe gegen Dementia.
ATE181333T1 (de) Azirdin-derivate, deren herstellung und verwendung
FI956055A (fi) Tekijä VII:sta johdettuja peptidejä
ATE194282T1 (de) L-arginin und analoge als thrombozytenaggregationshemmer
DK0513613T3 (da) Hidtil ukendte polypeptider med affinitet for lipopolysaccharider og anvendelse heraf
ATE139995T1 (de) Substituierte benzhydrylamine als anknüpfungsmoleküle bei der festphasenpeptidsynthese
ATE180679T1 (de) Neue verbesserungen hinsichtlich der radiomarkierung von proteinen
KR930701451A (ko) 디알킬아미노알킬설포닐-26 프리스티나마이신 ii_b로부터 유도되는 신규한 염
DE69833646D1 (de) (3r)-3-amino-4-carboxybutyraldehydderivate die die il-1/beta freisetzung inhibieren
IT1196502B (it) Analoghi parzialmente retro invertiti della tuftsina
MX9605037A (es) Inhibidores de factor xa.
ITMI932153A1 (it) Peptidi retroinvertiti ad attivita' immunomodulatrice