Nothing Special   »   [go: up one dir, main page]

ATA70981A - Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der - Google Patents

Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der

Info

Publication number
ATA70981A
ATA70981A AT0070981A AT70981A ATA70981A AT A70981 A ATA70981 A AT A70981A AT 0070981 A AT0070981 A AT 0070981A AT 70981 A AT70981 A AT 70981A AT A70981 A ATA70981 A AT A70981A
Authority
AT
Austria
Prior art keywords
dichloranilino
phenylacetic acid
producing new
new salts
salts
Prior art date
Application number
AT0070981A
Other languages
English (en)
Other versions
AT370721B (de
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10519933&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATA70981(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to AT136582A priority Critical patent/AT380166B/de
Publication of ATA70981A publication Critical patent/ATA70981A/de
Application granted granted Critical
Publication of AT370721B publication Critical patent/AT370721B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
AT0070981A 1981-02-16 1981-02-16 Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der AT370721B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT136582A AT380166B (de) 1981-02-16 1982-04-06 Verfahren zur herstellung topisch applizierbarer pharmazeutischer praeparate, enthaltend salze von alkancarbonsaeuren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8105822A GB2093693B (en) 1981-02-24 1981-02-24 Pharmaceutical preparations for topical application which contain salts of alkanecarboxylic acids novel carboxylic acid salts and the production thereof

Publications (2)

Publication Number Publication Date
ATA70981A true ATA70981A (de) 1982-09-15
AT370721B AT370721B (de) 1983-04-25

Family

ID=10519933

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0070981A AT370721B (de) 1981-02-16 1981-02-16 Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der

Country Status (12)

Country Link
US (4) US4407824A (de)
AT (1) AT370721B (de)
CA (1) CA1180008A (de)
CY (2) CY1444A (de)
FR (2) FR2500751A1 (de)
GB (2) GB2093693B (de)
HK (1) HK83888A (de)
KE (1) KE3820A (de)
LU (1) LU83945A1 (de)
NL (1) NL193216C (de)
SE (2) SE448088B (de)
SG (1) SG33388G (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU83138A1 (de) * 1981-02-16 1981-09-11 T Eckert Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung
FR2526427A1 (fr) * 1982-05-04 1983-11-10 Bouchara Emile Nouveau sel d'indometacine, son procede de preparation et les compositions pharmaceutiques en renfermant
US4437053A (en) * 1982-05-10 1984-03-13 Diasonics (Nmr) Inc. Gradient power supply
CH655656B (de) * 1982-10-07 1986-05-15
ES8407042A1 (es) * 1982-10-08 1984-09-01 Espinos & Bofill Lab Sa Procedimiento para la obtencion de un nuevo derivado del sulpiride.
JPS59137408A (ja) * 1983-01-27 1984-08-07 Taisho Pharmaceut Co Ltd 軟膏
JPS59139315A (ja) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd クリ−ム剤
CH643138A5 (de) * 1983-08-29 1984-05-30 Mepha Ag Indomethacin enthaltende, gelartige salbe.
EP0147476B1 (de) * 1983-12-08 1990-07-11 Toko Yakuhin Industry Co., Ltd. Gelpräparate zur externen Applikation
US4670254A (en) * 1983-12-09 1987-06-02 Toko Yakuhin Industry Co., Ltd. Gel preparations for topical application of diclofenac sodium
DE3423589A1 (de) * 1984-06-27 1986-01-09 Wella Ag, 6100 Darmstadt Oxidationshaarfaerbemittel auf basis einer niedrigviskosen traegermasse
IT1178411B (it) * 1984-09-06 1987-09-09 Sigma Tau Ind Farmaceuti Sale di d,l-lisina dell'acido 1-(4-clorobenzoil)-5-metossi-2-metil-1h-indol-3 acetico, procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
CA1265288A (en) * 1984-11-22 1990-01-30 E. I. Du Pont De Nemours And Company Curable fluoroelastomer composition
US4980084A (en) * 1985-09-11 1990-12-25 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Water rinsable petroleum jelly compositions
US4690774A (en) * 1985-09-11 1987-09-01 Chesebrough Pond's Inc. Novel translucent water in oil emulsions
US4832858A (en) * 1987-02-19 1989-05-23 Chesebrough-Pond's Inc. Water dispersible petroleum jelly compositions
US4960892A (en) * 1988-06-10 1990-10-02 American Home Products Corporation Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
TW225536B (de) * 1990-08-23 1994-06-21 Ciba Geigy Ag
US5444076A (en) * 1990-11-26 1995-08-22 Roemmers S.A.I.C.F. Pharmaceutical preparation for topical application
EP0592569A1 (de) * 1991-07-03 1994-04-20 Sano Corporation Zusammensetzung und verfahren zur transdermalen verabreichung von diclofenac
US6117907A (en) * 1993-04-14 2000-09-12 Sher; Neal A. Topical treatment of ocular pain after corneal surgery
JP3526887B2 (ja) * 1993-04-23 2004-05-17 帝國製薬株式会社 消炎鎮痛外用貼付剤
FI100692B (fi) * 1994-05-24 1998-02-13 Leiras Oy Menetelmä farmaseuttisten koostumusten valmistamiseksi, jolloin koostu mukset pohjautuvat mikroemulsiogeeleihin sekä uusia mikroemulsioihin p ohjautuvia geelejä
JPH11505503A (ja) * 1994-06-29 1999-05-21 ノバルティス アクチェンゲゼルシャフト 有機塩基カチオンとの２−〔（２，６−ジクロロフェニル）アミン〕フェニルアセトキシ酢酸の新規の塩類
US20030060657A1 (en) * 1998-04-28 2003-03-27 Russinsky Limited Process for the preparation of Aceclofenac
TWI290464B (en) 2000-09-01 2007-12-01 Novartis Consumer Health Sa Treatment of burns
DE10114561A1 (de) * 2001-03-24 2002-09-26 Wella Ag Verwendung von Mitteln enthaltend Kreatin, Kreatin und/oder deren Derivaten zur Verstärkung und Strukturverbesserung von keratinischen Fasern
ITMI20020986A1 (it) * 2002-05-10 2003-11-10 Acraf Composizione a base di diclofenac per il trattamento topico di affezioni del cavo orofaringeo
PE20040844A1 (es) 2002-11-26 2004-12-30 Novartis Ag Acidos fenilaceticos y derivados como inhibidores de la cox-2
ITMI20030269A1 (it) * 2003-02-14 2004-08-15 Advance Holdings Ltd Sale di cetilpiridino di un agente antiinfiammatorio
FR2854802B1 (fr) * 2003-05-12 2005-06-24 Galderma Res & Dev Procede de preparation d'une formulation contenant un principe actif microdose
EP2055298A1 (de) 2007-10-30 2009-05-06 Novartis AG Topische Zusammensetzung
WO2016038553A1 (en) 2014-09-10 2016-03-17 Novartis Consumer Health S.A. Topical diclofenac sodium compositions
CN116143647A (zh) * 2023-03-03 2023-05-23 长沙晶易医药科技股份有限公司 双氯芬酸二乙胺的新晶型及其制备方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US514839A (en) * 1894-02-13 sergeant
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren
US3558690A (en) * 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
CH470349A (de) * 1966-10-07 1969-03-31 Geigy Ag J R Verfahren zur Herstellung von neuen substituierten Phenylessigsäuren
CA960689A (en) * 1967-01-13 1975-01-07 Syntex Corporation 2-naphthyl acetic acid derivatives and compositions
US4048330A (en) * 1967-01-13 1977-09-13 Syntex Corporation Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia
US3896157A (en) * 1967-01-13 1975-07-22 Syntex Corp Dihydo 2-naphthylacetic acid derivatives
FR1546478A (fr) * 1967-01-27 1968-11-22 Rhone Poulenc Sa Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation
US3592902A (en) * 1967-04-13 1971-07-13 Sumitomo Chemical Co Injection
NO125724B (de) * 1967-12-20 1972-10-23 Ciba Geigy Ag
US3641040A (en) * 1968-03-27 1972-02-08 Ciba Geigy Corp Tertiary amino phenyl acetic acids
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
BR6915470D0 (pt) * 1969-03-24 1973-03-13 Syntex Corp Processo para preparar derivados de acido 2-(6'substituido 2'naftil)propionico e de seus sais
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
US3647858A (en) * 1970-05-01 1972-03-07 Merck & Co Inc Process for preparing 1-benzylidene-3-indenyl acetic acids
US4033816A (en) 1973-06-18 1977-07-05 The Upjohn Company Process for inhibiting platelet aggregation
US3936528A (en) * 1974-02-13 1976-02-03 Syntex Corporation Analgesic formulations having enhanced therapeutic activity
ES423834A1 (es) * 1974-03-02 1976-06-01 Roger Lab Procedimiento de obtencion de una nueva sal de piperacina del acido (1 - p - clorobenzoil - 2 - metil - 5 - metoxi - 3- indolil) acetico.
US4031243A (en) * 1975-07-03 1977-06-21 Juste, S.A. Quimico-Farmaceutica 2-(4-Isobutyl phenyl)butyric acid, salts thereof, and pharmaceutical compositions containing the same
PT66660B (en) * 1976-06-12 1978-11-13 Ciba Geigy Ag Process for the production of a derivative of phenylacetic
LU77316A1 (de) * 1977-05-11 1979-01-19
JPS549240A (en) * 1977-06-23 1979-01-24 Asahi Chem Ind Co Ltd New derivative of phenylglycolic acid, its preparation and analgesic and antiinflammatory agent contining it as effective component
GB2023000B (en) * 1978-06-17 1982-10-13 Kowa Co Antinflammatory analgesic gelled ointments
BE871335A (fr) * 1978-10-18 1979-04-18 Bago Sa Labor Derives solubles des acides 2-anilino-aryl-carboxyliques substitues utiles par la voie buccale comme agents anti-inflammatoires.
LU83138A1 (de) * 1981-02-16 1981-09-11 T Eckert Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
LU83945A1 (de) 1982-12-13
CY1444A (en) 1989-03-10
SE8203228L (sv) 1982-08-18
SG33388G (en) 1988-09-30
SE448088B (sv) 1987-01-19
CA1180008A (en) 1984-12-27
NL8100917A (nl) 1982-09-16
HK83888A (en) 1988-10-21
US4551475A (en) 1985-11-05
GB2143528A (en) 1985-02-13
US4619926A (en) 1986-10-28
FR2514348B1 (de) 1984-12-14
CY1443A (en) 1989-03-10
US4407824A (en) 1983-10-04
GB2093693A (en) 1982-09-08
FR2514348A1 (fr) 1983-04-15
US4784808A (en) 1988-11-15
FR2500751A1 (fr) 1982-09-03
AT370721B (de) 1983-04-25
FR2500751B1 (de) 1984-12-28
NL193216C (nl) 1999-03-03
SE8101064L (sv) 1982-08-18
GB2093693B (en) 1985-10-02
GB2143528B (en) 1985-10-02
NL193216B (nl) 1998-11-02
KE3820A (en) 1988-09-09
GB8418021D0 (en) 1984-08-22

Similar Documents

Publication Publication Date Title
AT370721B (de) Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der
AT382373B (de) Verfahren zur herstellung von neuen 2-(4-(4,4dialkyl-2,6-piperidin-dion-1-yl)-butyl)-1piperazinyl)-pyrimidinen
AT372371B (de) Verfahren zur herstellung von neuen salzen der 3-acetylaminopropansulfonsaeure
AT382150B (de) Verfahren zur herstellung von neuen 3-amino-2-oxo-azetidin-1-sulfonsaeurederivaten
AT375637B (de) Verfahren zur herstellung von neuen salzen der 5,5'-azobis-salicylsaeure
AT374781B (de) Verfahren zur herstellung der neuen 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapenta n-saeure
ATA443282A (de) Verfahren zur herstellung des neuen n-methyl-dglucamin-salzes von (+)-2-(2-fluor-4-biphenylyl)- propionsaeure
AT367432B (de) Verfahren zur herstellung von neuen 3",4"diacyltylosinderivaten
AT372382B (de) Verfahren zur herstellung von neuen oxiranylisocyanursaeureverbindungen
AT375943B (de) Verfahren zur herstellung von neuen mitosanverbindungen
AT354421B (de) Verfahren zur herstellung von neuen substituierten 3-(3'-amino-2'-hydroxy- propoxyphenyl)-acrylsaeurederivaten
AT376222B (de) Verfahren zur herstellung von neuen azinorifamycinverbindungen
AT374203B (de) Verfahren zur herstellung von neuen 2'-desoxy-3', 5'-di-o-alkylcarbonyl-5-fluoruridinderivaten
AT381314B (de) Verfahren zur herstellung des neuen n-methyl-d -glucaminsalzes der 3,4-dihydro-5-methyl-6
AT377975B (de) Verfahren zur herstellung von neuen nitrilotriessigsaeureamiden
AT368129B (de) Verfahren zur herstellung neuer salze von o-(2,6- dichloranilino)-phenylessigsaeure
AT358026B (de) Verfahren zur herstellung der neuen 2-(4- thenoyl-(3')-phenyl)-propionsaeure und ihrer salze
AT368155B (de) Verfahren zur herstellung von neuen vincamonsalzen
ATA260385A (de) Verfahren zur herstellung des neuen d,l-lysinsalzes der 1-(4-chlorbenzoyl)-5-methoxy2-methyl-1h-indol-3-essigs|ure
AT374795B (de) Verfahren zur herstellung von neuen derivaten der pyrrol-2-essigsaeure
ATA351081A (de) Verfahren zur herstellung von neuen cephalosporan-saeurederivaten
ATA229583A (de) Verfahren zur herstellung der neuen 3,7,11,15tetramethyl-2,4,6,10,14-hexadecapentaensaeure
AT343636B (de) Verfahren zur herstellung der neuen 2-(2'-n,n-diathylaminoathoxy)-3- propionylbenzoesaure
AT362877B (de) Verfahren zur herstellung von neuen 3,7disubstituierten 3-cephem-4-carbonsaeureverbindungen
ATA160879A (de) Verfahren zur herstellung von neuen 3,7-di- substituierten 3-cephem-4-carbonsaeurever- bindungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee
ELA Expired due to lapse of time