OA12501A - Pyrazole derivatives for treating HIV. - Google Patents

Pyrazole derivatives for treating HIV. Download PDF

Info

Publication number: OA12501A
Authority: OA; OAPI
Prior art keywords: pyrazol; methyl; oxy; diethyl; dichlorophenoxy
Prior art date: 2001-04-10

Application number

OA1200300258A

Other languages

English (en)

Inventor

Lyn Howard Jones

Charles Eric Mowbray

David Anthony Price

Matthew Duncan Selby

Paul Anthony Stupple

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-10

Filing date

2002-04-04

Publication date

2006-05-26

2001-04-10 Priority claimed from GB0108999A external-priority patent/GB0108999D0/en

2001-11-15 Priority claimed from GB0127426A external-priority patent/GB0127426D0/en

2002-04-04 Application filed by Pfizer filed Critical Pfizer

2006-05-26 Publication of OA12501A publication Critical patent/OA12501A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

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Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Virology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

OA1200300258A 2001-04-10 2002-04-04 Pyrazole derivatives for treating HIV. OA12501A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0108999A GB0108999D0 (en)	2001-04-10	2001-04-10	Pyrazole derivatives
GB0127426A GB0127426D0 (en)	2001-11-15	2001-11-15	Pyrazole derivatives

Publications (1)

Publication Number	Publication Date
OA12501A true OA12501A (en)	2006-05-26

Family

ID=26245955

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200300258A OA12501A (en)	2001-04-10	2002-04-04	Pyrazole derivatives for treating HIV.

Country Status (43)

Country	Link
US (4)	US7109228B2 (de)
EP (2)	EP1762567B1 (de)
JP (1)	JP3806090B2 (de)
KR (1)	KR100569324B1 (de)
CN (1)	CN100408564C (de)
AR (2)	AR037319A1 (de)
AT (2)	ATE556059T1 (de)
AU (1)	AU2002242926B2 (de)
BG (1)	BG66349B1 (de)
BR (1)	BRPI0208811B8 (de)
CA (1)	CA2443449C (de)
CR (1)	CR7069A (de)
CY (2)	CY1107626T1 (de)
CZ (1)	CZ305099B6 (de)
DE (1)	DE60219292T2 (de)
DK (2)	DK1762567T3 (de)
DO (1)	DOP2002000378A (de)
EA (1)	EA007184B1 (de)
EE (1)	EE05400B1 (de)
ES (2)	ES2385659T3 (de)
GE (1)	GEP20053619B (de)
HK (1)	HK1063781A1 (de)
HR (1)	HRP20030783B1 (de)
HU (1)	HU229025B1 (de)
IL (2)	IL157875A0 (de)
IS (1)	IS2734B (de)
MA (1)	MA27009A1 (de)
ME (1)	ME00558A (de)
MX (1)	MXPA03009380A (de)
MY (1)	MY146669A (de)
NO (1)	NO326518B1 (de)
NZ (1)	NZ529403A (de)
OA (1)	OA12501A (de)
PA (1)	PA8543601A1 (de)
PE (1)	PE20021056A1 (de)
PL (3)	PL217224B1 (de)
PT (2)	PT1762567E (de)
RS (1)	RS51166B (de)
SI (2)	SI1762567T1 (de)
SK (1)	SK287858B6 (de)
TW (1)	TWI333488B (de)
UY (1)	UY27248A1 (de)
WO (1)	WO2002085860A1 (de)

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2002
- 2002-04-04 MX MXPA03009380A patent/MXPA03009380A/es active IP Right Grant
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- 2002-04-04 DK DK06126433.9T patent/DK1762567T3/da active
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- 2002-04-04 AT AT06126433T patent/ATE556059T1/de active
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2003
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2004
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2005
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2007
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2008
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2010
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2011
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Also Published As

Publication number	Publication date
NO326518B1 (no)	2008-12-22
CA2443449A1 (en)	2002-10-31
BR0208811A (pt)	2004-03-09
BRPI0208811B8 (pt)	2021-05-25
PL365026A1 (en)	2004-12-27
PT1377556E (pt)	2007-06-06
US20060020012A1 (en)	2006-01-26
RS51166B (sr)	2010-10-31
AR037319A1 (es)	2004-11-03
US7435728B2 (en)	2008-10-14
CR7069A (es)	2007-12-17
NZ529403A (en)	2005-06-24
HUP0303735A3 (en)	2004-07-28
BRPI0208811B1 (pt)	2018-03-13
ME00558A (en)	2011-12-20
EA007184B1 (ru)	2006-08-25
PL216985B1 (pl)	2014-06-30
AR076259A2 (es)	2011-06-01
IS6939A (is)	2003-09-04
US20090215712A1 (en)	2009-08-27
ATE358669T1 (de)	2007-04-15
SI1762567T1 (sl)	2012-08-31
ATE556059T1 (de)	2012-05-15
ES2283532T3 (es)	2007-11-01
CY1107626T1 (el)	2013-04-18
YU77503A (sh)	2006-05-25
BG108244A (bg)	2005-04-30
HRP20030783A2 (en)	2005-08-31
CZ20032676A3 (cs)	2004-11-10
CN100408564C (zh)	2008-08-06
EP1762567B1 (de)	2012-05-02
PL217629B1 (pl)	2014-08-29
EP1377556B1 (de)	2007-04-04
HUP0303735A2 (hu)	2004-03-01
EE05400B1 (et)	2011-04-15
DE60219292T2 (de)	2008-04-10
PL217224B1 (pl)	2014-06-30
TWI333488B (en)	2010-11-21
GEP20053619B (en)	2005-09-26
DK1762567T3 (da)	2012-06-25
SK12442003A3 (sk)	2004-12-01
AU2002242926B2 (en)	2007-10-11
US8063044B2 (en)	2011-11-22
NO20034523L (no)	2003-12-09
HRP20030783B1 (en)	2011-11-30
EP1762567A1 (de)	2007-03-14
JP3806090B2 (ja)	2006-08-09
HU229025B1 (en)	2013-07-29
MA27009A1 (fr)	2004-12-20
US7109228B2 (en)	2006-09-19
BG66349B1 (bg)	2013-08-30
CY1113515T1 (el)	2016-06-22
US20030100554A1 (en)	2003-05-29
CN1514828A (zh)	2004-07-21
PL396946A1 (pl)	2012-01-02
IS2734B (is)	2011-04-15
HK1063781A1 (en)	2005-01-14
KR100569324B1 (ko)	2006-04-07
IL157875A0 (en)	2004-03-28
PL398536A1 (pl)	2012-06-04
IL157875A (en)	2010-05-17
EA200300943A1 (ru)	2004-08-26
NO20034523D0 (no)	2003-10-09
MXPA03009380A (es)	2004-04-21
DK1377556T3 (da)	2007-07-16
US20120029192A1 (en)	2012-02-02
PE20021056A1 (es)	2002-12-03
ES2385659T3 (es)	2012-07-27
UY27248A1 (es)	2002-11-29
EE200300497A (et)	2004-02-16
CA2443449C (en)	2008-11-04
EP1377556A1 (de)	2004-01-07
DE60219292D1 (de)	2007-05-16
WO2002085860A1 (en)	2002-10-31
PA8543601A1 (es)	2002-10-31
JP2004531535A (ja)	2004-10-14
PT1762567E (pt)	2012-07-16
SI1377556T1 (sl)	2007-08-31
CZ305099B6 (cs)	2015-05-06
SK287858B6 (sk)	2012-01-04
MY146669A (en)	2012-09-14
DOP2002000378A (es)	2002-10-15
KR20040007496A (ko)	2004-01-24

Publication	Publication Date	Title
OA12501A (en)	2006-05-26	Pyrazole derivatives for treating HIV.
AU2002242926A1 (en)	2003-04-17	Pyrazole derivatives for treating HIV
US7141585B2 (en)	2006-11-28	Pyrazole derivatives
WO2000024745A1 (en)	2000-05-04	PYRAZOLOPYRIMIDINONE cGMP PDE5 INHIBITORS FOR THE TREATMENT OF SEXUAL DYSFUNCTION
MXPA05002735A (es)	2005-05-23	Derivados de pirazol.
EP1556381B1 (de)	2008-02-20	Pyrazolamide zur behandlung von hiv-infektionen
OA12920A (en)	2006-10-13	4-(3,5-dicyanophenoxy)pyrazole derivatives for useas reverse transcriptase modulators in the treatment of I.A H.I.V.
EP1556359B1 (de)	2008-06-18	Pyrazolderivate und deren verwendung als therapeutische mittel für durch hiv vermittelte krankheiten