NO892476L - Fremgangsmaate for fremstilling av benzazepinderivater. - Google Patents

Fremgangsmaate for fremstilling av benzazepinderivater.

Info

Publication number: NO892476L
Authority: NO; Norway
Prior art keywords: bridge; procedure; alkyl; benzazepine derivatives; halogen
Prior art date: 1988-06-15

Application number

NO89892476A

Other languages

English (en)

Other versions

NO173865B (no

NO892476D0 (no

NO173865C (no

Inventor

Frederik Christian Groenvald

Peter Hoengaard Andersen

Peter Faarup

Erling Guddal

Kristian Tage Hansen

Louis Brammer Hansen

Erik Bardum Nielsen

Original Assignee

Novo Industri As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-06-15

Filing date

1989-06-14

Publication date

1989-12-18

1989-06-14 Application filed by Novo Industri As filed Critical Novo Industri As

1989-06-14 Publication of NO892476D0 publication Critical patent/NO892476D0/no

1989-12-18 Publication of NO892476L publication Critical patent/NO892476L/no

1993-11-08 Publication of NO173865B publication Critical patent/NO173865B/no

1994-02-16 Publication of NO173865C publication Critical patent/NO173865C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO892476A 1988-06-15 1989-06-14 Analogifremgangsmaate for fremstilling av terapeutisk aktive 2,3,4,5-tetrahydro-1h-3-benzazepiner NO173865C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK325188A DK325188D0 (da)	1988-06-15	1988-06-15	Hidtil ukendte benzazepinderivater

Publications (4)

Publication Number	Publication Date
NO892476D0 NO892476D0 (no)	1989-06-14
NO892476L true NO892476L (no)	1989-12-18
NO173865B NO173865B (no)	1993-11-08
NO173865C NO173865C (no)	1994-02-16

Family

ID=8120790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO892476A NO173865C (no)	1988-06-15	1989-06-14	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2,3,4,5-tetrahydro-1h-3-benzazepiner

Country Status (15)

Country	Link
US (2)	US5010074A (no)
EP (1)	EP0347672B1 (no)
JP (1)	JP2769718B2 (no)
AT (1)	ATE102188T1 (no)
AU (1)	AU622911B2 (no)
CA (1)	CA1317938C (no)
DE (1)	DE68913367T2 (no)
DK (1)	DK325188D0 (no)
ES (1)	ES2061794T3 (no)
FI (1)	FI93354C (no)
IE (1)	IE891932L (no)
IL (1)	IL90533A (no)
NO (1)	NO173865C (no)
NZ (1)	NZ229521A (no)
PT (1)	PT90883B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK67489D0 (da) *	1989-02-14	1989-02-14	Novo Industri As	Nye benzazepinderivater
US5158948A (en) *	1990-11-16	1992-10-27	Abbott Laboratories	Tetracyclic spirobenzazepine dopamine antagonists
DK23392D0 (da) *	1992-02-24	1992-02-24	Novo Nordisk As	Heterocykliske forbindelser, deres anvendelse og fremstilling
US5470850A (en) *	1992-02-24	1995-11-28	Novo Nordisk A/S	2,3,4,5-tetrahydro-1H-3-benzazepines
ATE245986T1 (de) *	1997-03-12	2003-08-15	Addex Pharmaceuticals Sa	Verwendung von 8-nitro-2,3,4,5-tetrahydro-1h-3- benzazepinen zur herstellung von pharmazeutischen zusammenstellungen zur behandlung von schlafstörungen
US6277844B1 (en)	1998-09-14	2001-08-21	Sydney Spector	Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis
GB0130576D0 (en) *	2001-12-20	2002-02-06	Cenes Ltd	Dopamine D1 receptor agonist pro-drug compounds & derivatives
US7211574B2 (en) *	2002-08-29	2007-05-01	Schering Corporation	Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders
NZ540148A (en)	2002-12-20	2007-11-30	Glaxo Group Ltd	Benzazepine derivatives for the treatment of neurological disorders
CN1823059A (zh) *	2003-05-22	2006-08-23	先灵公司	作为治疗肥胖和CNS疾病的选择性D<sub>1</sub>/D<sub>5</sub>受体拮抗剂的5－H－苯并[D]萘并[2,1－B]氮杂䓬衍生物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1268243A (en) *	1968-03-11	1972-03-22	Wallace & Tiernan Inc	0,2,4,5,-tetrahydro-3h,3-benzazepines
US4210749A (en) *	1974-11-12	1980-07-01	Pennwalt Corporation	Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines
ZA792044B (en) *	1978-05-08	1980-05-28	Scherico Ltd	Substituted 1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof,and pharmaceutical compositions containing them
US4284556A (en) *	1980-01-31	1981-08-18	Smithkline Corporation	7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4327023A (en) *	1980-01-31	1982-04-27	Smithkline Corporation	Intermediates for preparing 7,8-amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
DK180485D0 (da) *	1985-04-22	1985-04-23	Novo Industri As	Nitrogenholdige forbindelser
HU199805B (en) *	1986-01-16	1990-03-28	Schering Corp	Process for producing condensed benzazepine derivatives and pharmaceutical compositions comprising such compounds
EP0244088A3 (en) *	1986-04-03	1989-03-15	Smithkline Beecham Corporation	1-phenyl-3-benzazepine compounds and medicaments containing these compounds for treating gastrointestinal motility disorders

1988
- 1988-06-15 DK DK325188A patent/DK325188D0/da not_active Application Discontinuation
1989
- 1989-06-05 IL IL9053389A patent/IL90533A/en unknown
- 1989-06-09 ES ES89110490T patent/ES2061794T3/es not_active Expired - Lifetime
- 1989-06-09 DE DE68913367T patent/DE68913367T2/de not_active Expired - Lifetime
- 1989-06-09 EP EP89110490A patent/EP0347672B1/en not_active Expired - Lifetime
- 1989-06-09 AT AT89110490T patent/ATE102188T1/de not_active IP Right Cessation
- 1989-06-12 US US07/365,250 patent/US5010074A/en not_active Expired - Lifetime
- 1989-06-13 CA CA000602684A patent/CA1317938C/en not_active Expired - Lifetime
- 1989-06-13 NZ NZ229521A patent/NZ229521A/en unknown
- 1989-06-14 NO NO892476A patent/NO173865C/no not_active IP Right Cessation
- 1989-06-14 AU AU36359/89A patent/AU622911B2/en not_active Expired
- 1989-06-15 IE IE891932A patent/IE891932L/xx not_active IP Right Cessation
- 1989-06-15 FI FI892946A patent/FI93354C/fi active IP Right Grant
- 1989-06-15 PT PT90883A patent/PT90883B/pt not_active IP Right Cessation
- 1989-06-15 JP JP1150662A patent/JP2769718B2/ja not_active Expired - Lifetime
1990
- 1990-02-07 US US07/477,450 patent/US5025009A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NZ229521A (en)	1991-12-23
FI892946A0 (fi)	1989-06-15
JP2769718B2 (ja)	1998-06-25
IL90533A0 (en)	1990-01-18
DK325188D0 (da)	1988-06-15
PT90883B (pt)	1994-12-30
US5025009A (en)	1991-06-18
US5010074A (en)	1991-04-23
DE68913367D1 (de)	1994-04-07
FI892946A (fi)	1989-12-16
FI93354B (fi)	1994-12-15
IE891932L (en)	1989-12-15
AU622911B2 (en)	1992-04-30
PT90883A (pt)	1989-12-29
CA1317938C (en)	1993-05-18
FI93354C (fi)	1995-03-27
AU3635989A (en)	1989-12-21
DE68913367T2 (de)	1994-06-01
NO173865B (no)	1993-11-08
NO892476D0 (no)	1989-06-14
NO173865C (no)	1994-02-16
ATE102188T1 (de)	1994-03-15
EP0347672A1 (en)	1989-12-27
EP0347672B1 (en)	1994-03-02
ES2061794T3 (es)	1994-12-16
IL90533A (en)	1994-05-30
JPH0240364A (ja)	1990-02-09

Publication	Publication Date	Title
AU5752194A (en)	1994-09-29	Benzimidazole compounds, their use and preparation
AU635575B2 (en)	1993-03-25	4- and 6-carbamates related to physostigmine, a process and intermediates for their preparation and their use as medicaments
ATE263771T1 (de)	2004-04-15	Totalsynthese von acylfulvenen mit antitumorwirkung
IE883003L (en)	1989-04-05	Pyridine derivatives and related intermediates
AU8405891A (en)	1992-03-30	Indole derivative and medicine
NO892476L (no)	1989-12-18	Fremgangsmaate for fremstilling av benzazepinderivater.
NO161564C (no)	1989-08-30	Analogifremgangsmaate ved fremstilling av terapeutisk aktive beta-carbolin-3-oxadiazolylderivater.
ZA887399B (en)	1990-05-30	4-aminopyridine derivatives
DK0430201T3 (no)	1997-06-16
HU9201887D0 (en)	1992-08-28	Process for the production of //aralkyl-piperidine-4-yl/-methyl/-2a,3,4,5-tetrahydro-1-/2h/-acenaphtylene-1-on derivatives and of medical preparations containing them as active agents
EP0285284A3 (en)	1989-03-29	N-phenethylaminoalkyl-benzamide anti-arrhythmia agents
NO173991C (no)	1994-03-02	Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,5-ditiazocin-derivater
NO894384L (no)	1990-05-07	Forbindelser for behandling av urininkontinens.
NO914192L (no)	1992-04-27	8-azabicyklo(3.2.1)oktylalkylthiazolidinoner, fremgangsmaate for fremstilling og anvendelse som medikamenter
GR3006108T3 (no)	1993-06-21
ATE283269T1 (de)	2004-12-15	5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems
DK424888D0 (da)	1988-07-29	Naphthothiazepinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende saadanne derivater
ATE56432T1 (de)	1990-09-15	Substituierte 1,3,4,9-tetrahydropyrano(3,4b>indole-1-essigs\|ure.
EP0381114A3 (en)	1991-11-13	Exo-3',4'-0-benzylidene-3"-demethylchartreusin and its salts
DK294389A (da)	1989-12-16	Nye benzazepin derivater
PH24971A (en)	1990-12-26	N2-thiocylcarbazate compounds and derivatives thereof

Legal Events

Date	Code	Title	Description
2009-07-06	MK1K	Patent expired