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DK325188D0 - Hidtil ukendte benzazepinderivater - Google Patents

Hidtil ukendte benzazepinderivater

Info

Publication number
DK325188D0
DK325188D0 DK325188A DK325188A DK325188D0 DK 325188 D0 DK325188 D0 DK 325188D0 DK 325188 A DK325188 A DK 325188A DK 325188 A DK325188 A DK 325188A DK 325188 D0 DK325188 D0 DK 325188D0
Authority
DK
Denmark
Prior art keywords
bridge
unknown
alkyl
benzazepine derivatives
halogen
Prior art date
Application number
DK325188A
Other languages
English (en)
Inventor
Frederik Christian Groenvald
Peter Hoengaard Andersen
Peter Faarup
Erling Guddal
Kristian Tage Hansen
Louis Brammer Hansen
Erik Bardrum Nielsen
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of DK325188D0 publication Critical patent/DK325188D0/da
Priority to DK325188A priority Critical patent/DK325188D0/da
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to IL9053389A priority patent/IL90533A/en
Priority to DE68913367T priority patent/DE68913367T2/de
Priority to ES89110490T priority patent/ES2061794T3/es
Priority to AT89110490T priority patent/ATE102188T1/de
Priority to EP89110490A priority patent/EP0347672B1/en
Priority to US07/365,250 priority patent/US5010074A/en
Priority to NZ229521A priority patent/NZ229521A/en
Priority to CA000602684A priority patent/CA1317938C/en
Priority to NO892476A priority patent/NO173865C/no
Priority to AU36359/89A priority patent/AU622911B2/en
Priority to JP1150662A priority patent/JP2769718B2/ja
Priority to IE891932A priority patent/IE891932L/xx
Priority to DK294389A priority patent/DK163993C/da
Priority to FI892946A priority patent/FI93354C/fi
Priority to PT90883A priority patent/PT90883B/pt
Priority to US07/477,450 priority patent/US5025009A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK325188A 1988-06-15 1988-06-15 Hidtil ukendte benzazepinderivater DK325188D0 (da)

Priority Applications (17)

Application Number Priority Date Filing Date Title
DK325188A DK325188D0 (da) 1988-06-15 1988-06-15 Hidtil ukendte benzazepinderivater
IL9053389A IL90533A (en) 1988-06-15 1989-06-05 History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing them
DE68913367T DE68913367T2 (de) 1988-06-15 1989-06-09 Benzazepinderivate.
ES89110490T ES2061794T3 (es) 1988-06-15 1989-06-09 Nuevos derivados de benzazepina.
AT89110490T ATE102188T1 (de) 1988-06-15 1989-06-09 Benzazepinderivate.
EP89110490A EP0347672B1 (en) 1988-06-15 1989-06-09 Benzazepine derivatives
US07/365,250 US5010074A (en) 1988-06-15 1989-06-12 Novel benzazepine derivatives
NZ229521A NZ229521A (en) 1988-06-15 1989-06-13 2,3,4,5-tetrahydro-1h-3-benzazepines and pharmaceutical compositions
CA000602684A CA1317938C (en) 1988-06-15 1989-06-13 Benzazapin derivatives
NO892476A NO173865C (no) 1988-06-15 1989-06-14 Analogifremgangsmaate for fremstilling av terapeutisk aktive 2,3,4,5-tetrahydro-1h-3-benzazepiner
AU36359/89A AU622911B2 (en) 1988-06-15 1989-06-14 Novel benzazepine derivatives
JP1150662A JP2769718B2 (ja) 1988-06-15 1989-06-15 新規ベンズアセピン誘導体
IE891932A IE891932L (en) 1988-06-15 1989-06-15 Novel benzazepine derivatives
DK294389A DK163993C (da) 1988-06-15 1989-06-15 5,7,8-substituerede 2,3,4,5-tetrahydro-1h-3-benzazepiner, fremstilling af disse, samt farmaceutiske praeparater indeholdende disse
FI892946A FI93354C (fi) 1988-06-15 1989-06-15 Menetelmä uusien terapeuttisesti käyttökelpoisten 2,3,4,5-tetrahydro-1H-3-bentsoatsepiinijohdannaisten valmistamiseksi
PT90883A PT90883B (pt) 1988-06-15 1989-06-15 Processo de preparacao de 2,3,4,5-tetra-hidro-ih-3-benzazepinas e de composicoes farmaceuticas que as contem
US07/477,450 US5025009A (en) 1988-06-15 1990-02-07 Novel benzazepine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK325188A DK325188D0 (da) 1988-06-15 1988-06-15 Hidtil ukendte benzazepinderivater

Publications (1)

Publication Number Publication Date
DK325188D0 true DK325188D0 (da) 1988-06-15

Family

ID=8120790

Family Applications (1)

Application Number Title Priority Date Filing Date
DK325188A DK325188D0 (da) 1988-06-15 1988-06-15 Hidtil ukendte benzazepinderivater

Country Status (15)

Country Link
US (2) US5010074A (da)
EP (1) EP0347672B1 (da)
JP (1) JP2769718B2 (da)
AT (1) ATE102188T1 (da)
AU (1) AU622911B2 (da)
CA (1) CA1317938C (da)
DE (1) DE68913367T2 (da)
DK (1) DK325188D0 (da)
ES (1) ES2061794T3 (da)
FI (1) FI93354C (da)
IE (1) IE891932L (da)
IL (1) IL90533A (da)
NO (1) NO173865C (da)
NZ (1) NZ229521A (da)
PT (1) PT90883B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater
US5158948A (en) * 1990-11-16 1992-10-27 Abbott Laboratories Tetracyclic spirobenzazepine dopamine antagonists
DK23392D0 (da) * 1992-02-24 1992-02-24 Novo Nordisk As Heterocykliske forbindelser, deres anvendelse og fremstilling
US5470850A (en) * 1992-02-24 1995-11-28 Novo Nordisk A/S 2,3,4,5-tetrahydro-1H-3-benzazepines
ATE245986T1 (de) * 1997-03-12 2003-08-15 Addex Pharmaceuticals Sa Verwendung von 8-nitro-2,3,4,5-tetrahydro-1h-3- benzazepinen zur herstellung von pharmazeutischen zusammenstellungen zur behandlung von schlafstörungen
US6277844B1 (en) 1998-09-14 2001-08-21 Sydney Spector Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
US7211574B2 (en) * 2002-08-29 2007-05-01 Schering Corporation Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders
NZ540148A (en) 2002-12-20 2007-11-30 Glaxo Group Ltd Benzazepine derivatives for the treatment of neurological disorders
CN1823059A (zh) * 2003-05-22 2006-08-23 先灵公司 作为治疗肥胖和CNS疾病的选择性D<sub>1</sub>/D<sub>5</sub>受体拮抗剂的5－H－苯并[D]萘并[2,1－B]氮杂䓬衍生物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268243A (en) * 1968-03-11 1972-03-22 Wallace & Tiernan Inc 0,2,4,5,-tetrahydro-3h,3-benzazepines
US4210749A (en) * 1974-11-12 1980-07-01 Pennwalt Corporation Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines
ZA792044B (en) * 1978-05-08 1980-05-28 Scherico Ltd Substituted 1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof,and pharmaceutical compositions containing them
US4284556A (en) * 1980-01-31 1981-08-18 Smithkline Corporation 7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4327023A (en) * 1980-01-31 1982-04-27 Smithkline Corporation Intermediates for preparing 7,8-amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
HU199805B (en) * 1986-01-16 1990-03-28 Schering Corp Process for producing condensed benzazepine derivatives and pharmaceutical compositions comprising such compounds
EP0244088A3 (en) * 1986-04-03 1989-03-15 Smithkline Beecham Corporation 1-phenyl-3-benzazepine compounds and medicaments containing these compounds for treating gastrointestinal motility disorders

Also Published As

Publication number Publication date
NZ229521A (en) 1991-12-23
FI892946A0 (fi) 1989-06-15
JP2769718B2 (ja) 1998-06-25
IL90533A0 (en) 1990-01-18
PT90883B (pt) 1994-12-30
US5025009A (en) 1991-06-18
NO892476L (no) 1989-12-18
US5010074A (en) 1991-04-23
DE68913367D1 (de) 1994-04-07
FI892946A (fi) 1989-12-16
FI93354B (fi) 1994-12-15
IE891932L (en) 1989-12-15
AU622911B2 (en) 1992-04-30
PT90883A (pt) 1989-12-29
CA1317938C (en) 1993-05-18
FI93354C (fi) 1995-03-27
AU3635989A (en) 1989-12-21
DE68913367T2 (de) 1994-06-01
NO173865B (no) 1993-11-08
NO892476D0 (no) 1989-06-14
NO173865C (no) 1994-02-16
ATE102188T1 (de) 1994-03-15
EP0347672A1 (en) 1989-12-27
EP0347672B1 (en) 1994-03-02
ES2061794T3 (es) 1994-12-16
IL90533A (en) 1994-05-30
JPH0240364A (ja) 1990-02-09

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment