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NO20091989L - Forbindelser som modulerer c-fms og/eller C-kit aktivitet og deres anvendelse - Google Patents

Forbindelser som modulerer c-fms og/eller C-kit aktivitet og deres anvendelse

Info

Publication number
NO20091989L
NO20091989L NO20091989A NO20091989A NO20091989L NO 20091989 L NO20091989 L NO 20091989L NO 20091989 A NO20091989 A NO 20091989A NO 20091989 A NO20091989 A NO 20091989A NO 20091989 L NO20091989 L NO 20091989L
Authority
NO
Norway
Prior art keywords
fms
compounds
modulate
kit activity
kit
Prior art date
Application number
NO20091989A
Other languages
English (en)
Other versions
NO342175B1 (no
Inventor
Dean R Artis
Chao Zhang
Guoxian Wu
Hongyao Zhu
Ryan Bremer
Marika Nespi
Prabha N Ibrahim
Jiazhong Zhang
Original Assignee
Plexxikon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39322825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20091989(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Plexxikon Inc filed Critical Plexxikon Inc
Publication of NO20091989L publication Critical patent/NO20091989L/no
Publication of NO342175B1 publication Critical patent/NO342175B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
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  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
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Abstract

Det tilveiebringes herved forbindelser som er aktive på reseptorprotein-tyrosinkinasene c-kit og/eller c-fms. Det tilveiebringes herved også preparater anvendelige for behandling av c-kit-medierte sykdommer eller lidelser og/eller c-fms-medierte sykdommer eller lidelser, og metoder for anvendelsen derav.
NO20091989A 2006-11-22 2009-05-22 Kjemiske forbindelser, preparater omfattende slike forbindelser, slike forbindelser og preparater for behandling av sykdom samt sett omfattende slike forbindelser NO342175B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86074906P 2006-11-22 2006-11-22
PCT/US2007/085289 WO2008064255A2 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor

Publications (2)

Publication Number Publication Date
NO20091989L true NO20091989L (no) 2009-06-19
NO342175B1 NO342175B1 (no) 2018-04-09

Family

ID=39322825

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091989A NO342175B1 (no) 2006-11-22 2009-05-22 Kjemiske forbindelser, preparater omfattende slike forbindelser, slike forbindelser og preparater for behandling av sykdom samt sett omfattende slike forbindelser

Country Status (35)

Country Link
US (8) US7893075B2 (no)
EP (1) EP2086972B1 (no)
JP (4) JP2010510321A (no)
KR (1) KR101506044B1 (no)
CN (2) CN103497188B (no)
AR (1) AR063878A1 (no)
AU (1) AU2007323644B2 (no)
BR (1) BRPI0721137B8 (no)
CA (1) CA2670362C (no)
CL (1) CL2007003326A1 (no)
CO (1) CO6180438A2 (no)
CR (1) CR10817A (no)
DK (1) DK2086972T3 (no)
EC (1) ECSP099357A (no)
ES (1) ES2447779T3 (no)
GT (1) GT200700101A (no)
HK (1) HK1133649A1 (no)
IL (1) IL198624A (no)
MX (1) MX2009005428A (no)
MY (1) MY158447A (no)
NI (1) NI200900093A (no)
NO (1) NO342175B1 (no)
NZ (1) NZ577011A (no)
PE (1) PE20081226A1 (no)
PL (1) PL2086972T3 (no)
PT (1) PT2086972E (no)
RU (1) RU2452738C2 (no)
SG (1) SG176511A1 (no)
SI (1) SI2086972T1 (no)
SV (1) SV2007002813A (no)
TW (1) TWI432431B (no)
UA (1) UA97816C2 (no)
UY (1) UY30732A1 (no)
WO (3) WO2008063888A2 (no)
ZA (1) ZA200903458B (no)

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US7498342B2 (en) * 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
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EP2245033B1 (en) * 2008-02-25 2011-08-31 F. Hoffmann-La Roche AG Pyrrolopyrazine kinase inhibitors
WO2009143018A2 (en) 2008-05-19 2009-11-26 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
US8119637B2 (en) * 2008-06-10 2012-02-21 Plexxikon Inc. Substituted pyrrolo[2,3-b]pyrazines and methods for kinase modulation, and indications therefor
EP2356116A1 (en) * 2008-11-20 2011-08-17 OSI Pharmaceuticals, Inc. Substituted pyrroloý2,3-b¨-pyridines and-pyrazines
CA2747784C (en) * 2008-12-24 2018-07-31 Bial - Portela & Ca, S.A. Imidazole compounds for use as enzyme inhibitors
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CN102753549A (zh) 2009-12-23 2012-10-24 普莱希科公司 用于激酶调节的化合物和方法及其适应症
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