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MXPA03006687A - Un metodo para preparar una esponja de colageno, un dispositivo para extraer una parte de una espuma de colageno y una de colageno alargada. - Google Patents

Un metodo para preparar una esponja de colageno, un dispositivo para extraer una parte de una espuma de colageno y una de colageno alargada.

Info

Publication number
MXPA03006687A
MXPA03006687A MXPA03006687A MXPA03006687A MXPA03006687A MX PA03006687 A MXPA03006687 A MX PA03006687A MX PA03006687 A MXPA03006687 A MX PA03006687A MX PA03006687 A MXPA03006687 A MX PA03006687A MX PA03006687 A MXPA03006687 A MX PA03006687A
Authority
MX
Mexico
Prior art keywords
collagen
sponge
foam
collagen sponge
extracting
Prior art date
Application number
MXPA03006687A
Other languages
English (en)
Inventor
Alfred Schaufler
Original Assignee
Nycomed Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Pharma As filed Critical Nycomed Pharma As
Publication of MXPA03006687A publication Critical patent/MXPA03006687A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/36—Surgical swabs, e.g. for absorbency or packing body cavities during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/046—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00463—Plasters use haemostatic
    • A61F2013/00472—Plasters use haemostatic with chemical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un metodo para preparar una esponja de colageno que comprende mezclar aire en un gel de colageno y asi obtener una espuma de colageno, la cual se seca. A partir del producto seco asi obtenido, la esponja de colageno se obtiene mediante el aislamiento de partes de esponja con un diametro de camara de mas de 0.75 mm y menos de 4 mm o partes con una dimension diagonal media de la camara de 3 mm. La esponja puede ser usada como un material para cerrar una lesion, posiblemente con un recubrimiento que comprende un adhesivo de fibrina, tal como una combinacion de fibrinogeno, trombina y aprotinina. Se describe un dispositivo para la extraccion de una parte de una espuma de colageno y para la degeneracion de otra parte de la espuma de colageno para un gel de colageno. Una esponja de colageno alargada que tiene un orificio o perforacion de paso a traves y una pared flexible se puede usar para restablecer paredes en un conducto gastrointestinal o un sistema de traquea de mamiferos.
MXPA03006687A 2001-01-25 2002-01-25 Un metodo para preparar una esponja de colageno, un dispositivo para extraer una parte de una espuma de colageno y una de colageno alargada. MXPA03006687A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200100135 2001-01-25
DKPA200100235 2001-02-13
PCT/IB2002/001452 WO2002070594A2 (en) 2001-01-25 2002-01-25 A method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge

Publications (1)

Publication Number Publication Date
MXPA03006687A true MXPA03006687A (es) 2004-03-12

Family

ID=26068956

Family Applications (3)

Application Number Title Priority Date Filing Date
MXPA03006689A MXPA03006689A (es) 2001-01-25 2002-01-25 Una suspension que comprende fibrinogeno, trombina y alcohol, un metodo para preparar dicha suspension, un metodo para recubrir un soporte con dicha suspension, un metodo de secado de un recubrimiento de un soporte, y una esponja de colageno recubier
MXPA03006687A MXPA03006687A (es) 2001-01-25 2002-01-25 Un metodo para preparar una esponja de colageno, un dispositivo para extraer una parte de una espuma de colageno y una de colageno alargada.
MXPA03006688A MXPA03006688A (es) 2001-01-25 2002-01-25 Portador con fibrinogeno solido y trombina solida.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MXPA03006689A MXPA03006689A (es) 2001-01-25 2002-01-25 Una suspension que comprende fibrinogeno, trombina y alcohol, un metodo para preparar dicha suspension, un metodo para recubrir un soporte con dicha suspension, un metodo de secado de un recubrimiento de un soporte, y una esponja de colageno recubier

Family Applications After (1)

Application Number Title Priority Date Filing Date
MXPA03006688A MXPA03006688A (es) 2001-01-25 2002-01-25 Portador con fibrinogeno solido y trombina solida.

Country Status (37)

Country Link
EP (4) EP1368419B1 (es)
JP (4) JP2004521115A (es)
KR (2) KR100830294B1 (es)
CN (3) CN1264578C (es)
AR (3) AR032800A1 (es)
AT (2) ATE310044T1 (es)
AU (3) AU2002307809B2 (es)
BG (3) BG66439B1 (es)
BR (3) BRPI0206708B8 (es)
CA (3) CA2434964C (es)
CL (1) CL2015003111A1 (es)
CR (1) CR7034A (es)
CZ (3) CZ20032199A3 (es)
DE (2) DE60203364T2 (es)
DK (2) DK1368419T3 (es)
EA (4) EA005697B1 (es)
EE (3) EE05685B1 (es)
EG (2) EG26417A (es)
ES (2) ES2253523T3 (es)
HK (2) HK1058319A1 (es)
HR (1) HRP20030648B1 (es)
HU (3) HU228810B1 (es)
IL (6) IL157096A0 (es)
IS (1) IS6885A (es)
ME (1) ME00587B (es)
MX (3) MXPA03006689A (es)
NO (3) NO327386B1 (es)
NZ (3) NZ527167A (es)
PL (3) PL206197B1 (es)
PT (1) PT1343542E (es)
RS (1) RS50866B (es)
SI (2) SI1343542T1 (es)
SK (3) SK288120B6 (es)
TW (2) TWI255726B (es)
UA (1) UA73028C2 (es)
UY (1) UY27136A1 (es)
WO (3) WO2002070594A2 (es)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020131933A1 (en) * 1996-01-16 2002-09-19 Yves Delmotte Biopolymer membrane and methods for its preparation
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US7252837B2 (en) 2002-06-28 2007-08-07 Ethicon, Inc. Hemostatic wound dressing and method of making same
US7279177B2 (en) 2002-06-28 2007-10-09 Ethicon, Inc. Hemostatic wound dressings and methods of making same
WO2004041254A1 (en) * 2002-11-04 2004-05-21 Nycomed Danmark Aps Coating of a particulate material with an organic solvent-based coating composition
JP4769578B2 (ja) * 2003-01-20 2011-09-07 一般財団法人化学及血清療法研究所 止血用材料
ATE455563T1 (de) 2003-04-04 2010-02-15 Tissuemed Ltd Zusammensetzungen für die gewebeadhäsion
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US20040265371A1 (en) 2003-06-25 2004-12-30 Looney Dwayne Lee Hemostatic devices and methods of making same
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US7186684B2 (en) 2003-08-07 2007-03-06 Ethicon, Inc. Hemostatic device containing a protein precipitate
RU2396985C2 (ru) 2004-08-03 2010-08-20 Тиссьюмед Лимитед Материалы, обладающие адгезией к тканям
US9358318B2 (en) 2004-10-20 2016-06-07 Ethicon, Inc. Method of making a reinforced absorbable multilayered hemostatic wound dressing
AU2005295367B2 (en) 2004-10-20 2010-12-02 Ethicon, Inc. A reinforced absorbable multilayered fabric for use in medical devices and method of manufacture
BRPI0516761B8 (pt) * 2004-10-20 2021-05-25 Ethicon Inc curativo hemostático de múltiplas camadas absorvível reforçado e método para a produção do mesmo
KR20060040329A (ko) * 2004-11-05 2006-05-10 나건 내시경을 통하여 도포 가능한 체내 지혈제 및 그 도포 방법
CN101267831B (zh) 2005-04-25 2013-04-24 麻省理工学院 用于促进止血和其它生理活动的组合物和方法
JP4864348B2 (ja) * 2005-05-27 2012-02-01 川澄化学工業株式会社 神経再生チューブ
US8133336B2 (en) 2006-02-03 2012-03-13 Tissuemed Limited Tissue-adhesive materials
WO2007092998A1 (en) 2006-02-14 2007-08-23 Commonwealth Scientific And Industrial Research Organisation Joining and/or sealing tissues through photo-activated cross-linking of matrix proteins
EP2012842B1 (en) 2006-04-25 2018-04-04 Massachusetts Institute of Technology Compositions and methods for affecting movement of contaminants, bodily fluids or other entities and/or affecting other physiological conditions
CA2651941C (en) 2006-05-31 2015-02-17 Baxter International Inc. Method for directed cell in-growth and controlled tissue regeneration in spinal surgery
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
US20080033331A1 (en) * 2006-08-04 2008-02-07 Macphee Martin Solid dressing for treating wounded tissue
GB0623607D0 (en) 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
CN101053679B (zh) * 2007-04-17 2010-05-26 浙江大学 一种纤维蛋白凝胶填充的聚合物多孔支架的制备方法
DE102007037053A1 (de) 2007-07-24 2009-01-29 Aesculap Ag Hämostyptikum für die minimal-invasive Operation
DE102007037056A1 (de) 2007-07-24 2009-01-29 Aesculap Ag Hämostyptikum
DE102007045066A1 (de) 2007-09-20 2009-04-02 Mike Ehrlich Material zur Blutstillung enthaltend synthetische Peptide oder Polysaccharide
DE102007000574A1 (de) 2007-10-25 2009-04-30 FILK Forschungsinstitut für Leder- und Kunstbahnen gGmbH Biologisch resorbierbares Schwammmaterial und Verfahren zu dessen Herstellung
CA2703103C (en) 2007-10-30 2017-05-09 Baxter Healthcare S.A. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
CN101214391B (zh) * 2007-12-27 2010-05-19 广州倍绣生物技术有限公司 一种高效生物胶封闭剂及其应用
WO2009109194A2 (en) 2008-02-29 2009-09-11 Ferrosan A/S Device for promotion of hemostasis and/or wound healing
WO2010002435A2 (en) * 2008-07-03 2010-01-07 Kulinets Irina B Hemostatic pouch and method to stabilize hemostatic components
ES2624484T3 (es) 2008-10-06 2017-07-14 3-D Matrix, Ltd. Tapón de tejido
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
ES2532428T3 (es) 2009-06-16 2015-03-26 Baxter International Inc Esponja hemostática
WO2011035020A1 (en) 2009-09-18 2011-03-24 Bioinspire Technologies, Inc. Free-standing biodegradable patch
US9271925B2 (en) 2013-03-11 2016-03-01 Bioinspire Technologies, Inc. Multi-layer biodegradable device having adjustable drug release profile
US9439941B2 (en) 2009-12-14 2016-09-13 The University Of Hong Kong Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells
MX2012007056A (es) 2009-12-16 2012-09-28 Baxter Healthcare Sa Esponja hemostatica.
RU2556960C2 (ru) 2010-01-28 2015-07-20 Омрикс Биофармасьютикалс Лтд. Способ обеспечения улучшенного уплотнения с помощью фибрина
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
CN103037845B (zh) 2010-06-01 2015-11-25 巴克斯特国际公司 用于制备干燥、稳定的止血组合物的方法
CA2801120C (en) 2010-06-01 2019-08-20 Baxter International Inc. Process for making dry and stable hemostatic compositions
BR112012030455B1 (pt) 2010-06-01 2021-08-17 Baxter Healthcare S.A. Processo para fabricar uma composição hemostática seca e estável, recipiente acabado final, e, kit para administrar uma composição hemostática
US20130183366A1 (en) 2010-07-20 2013-07-18 The Chemo-Sero-Therapeutic Research Institute Sheet preparation for tissue adhesion
ME02830B (me) * 2011-05-24 2018-01-20 Takeda As Umotani kolagenski nosač
RU2013155713A (ru) * 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран
CN102357259A (zh) 2011-07-28 2012-02-22 王珊珊 一种生物蛋白海绵及其制备方法
US20130041406A1 (en) * 2011-08-10 2013-02-14 Brian W. Bear Surgical staple with localized adjunct coating
EP2556842A1 (en) 2011-08-11 2013-02-13 Bioftalmik, S.L. Composition in the form of film comprising fibrinogen and a fibrinogen activator and the applications thereof
EP4137165A1 (en) 2011-10-11 2023-02-22 Baxter International Inc. Hemostatic compositions
EP4137164A1 (en) 2011-10-11 2023-02-22 Baxter International Inc. Hemostatic compositions
SA112330957B1 (ar) 2011-10-27 2015-08-09 باكستر انترناشونال انك. تركيبات لإيقاف النزف
RU2657955C2 (ru) 2012-03-06 2018-06-18 Ферросан Медикал Дивайсиз А/С Контейнер под давлением, содержащий гемостатическую пасту
AR091031A1 (es) * 2012-05-14 2014-12-30 Teijin Ltd Producto en planchas y material hemostatico
CA2871697C (en) * 2012-05-24 2020-08-25 Takeda Nycomed As Apparatus and process for providing a coiled collagen carrier
US10485715B2 (en) 2012-05-24 2019-11-26 Takeda As Packaging for form-stable coiled collagen carrier
CN104349797B (zh) 2012-06-12 2017-10-27 弗罗桑医疗设备公司 干止血组合物
US10793307B2 (en) 2012-07-06 2020-10-06 3-D Matrix, Ltd. Fill-finish process for peptide solutions
DE102013004420A1 (de) 2012-08-20 2014-02-20 Alexander Kopp Stützkörper und Verfahren zu seiner Herstellung
US10307509B2 (en) * 2012-12-07 2019-06-04 Baxter International Inc. Hemostatic foam
KR101401944B1 (ko) * 2012-12-11 2014-05-30 세원셀론텍(주) 콜라겐과 피브린이 혼합된 조직 실란트 및 그 제조방법
AU2014283170B2 (en) 2013-06-21 2017-11-02 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US10765774B2 (en) * 2013-07-09 2020-09-08 Ethicon, Inc. Hemostatic pad assembly kit and method
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ／エス 押し出し増強因子を含んでいる乾燥組成物
US10369237B2 (en) 2014-03-10 2019-08-06 3-D Matrix, Ltd. Sterilization and filtration of peptide compositions
KR20160127827A (ko) 2014-03-10 2016-11-04 가부시끼가이샤 쓰리디 매트릭스 자가-조립 펩타이드 조성물
EP3116524B1 (en) 2014-03-10 2018-11-28 3-D Matrix Ltd. Autoassembling peptides for the treatment of pulmonary bulla
JP6726852B2 (ja) 2014-10-13 2020-07-22 フェッローサン メディカル ディバイス エー／エス 止血および創傷治癒に使用するための乾燥組成物
US10653837B2 (en) 2014-12-24 2020-05-19 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
WO2017005590A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
US10814038B2 (en) 2016-01-06 2020-10-27 3-D Matrix, Ltd. Combination compositions
CN106267328B (zh) * 2016-09-20 2019-04-12 安徽思维特生物科技有限公司 一种聚己内酯-胎牛皮胶原纤维复合止血凝胶的制备方法
CN106730031A (zh) * 2016-12-30 2017-05-31 清华大学 一种用于脊髓损伤修复的仿生纤维蛋白水凝胶束及其制备方法
US11324703B2 (en) 2017-12-15 2022-05-10 3-D Matrix, Ltd. Surfactant peptide nanostructures and uses thereof in drug delivery
ES2968412T3 (es) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Método para preparar una composición hemostática
RU2679616C1 (ru) * 2018-07-02 2019-02-12 Государственное бюджетное учреждение здравоохранения города Москвы Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы Способ приготовления тромбофибринового сгустка, обладающего ростстимулирующими свойствами
JP7481008B2 (ja) * 2018-12-14 2024-05-10 株式会社ビーエムジー ２反応剤型のシート状組織接着補強材
CN112225937B (zh) * 2020-10-14 2022-11-01 中山大学 一种温敏型大孔生物水凝胶及其制备方法和应用
CN113117158B (zh) * 2021-03-10 2022-07-26 复旦大学 表面变性蛋白生物功能化修饰的材料及其制备方法和应用
CN114246974B (zh) * 2021-12-24 2023-11-03 中国人民解放军军事科学院军事医学研究院 一种止血贴的制备方法
CN114177346B (zh) * 2021-12-24 2023-05-26 中国人民解放军军事科学院军事医学研究院 一种止血组合物及止血贴与其应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1596789A (es) * 1968-11-27 1970-06-22
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
BR8102435A (pt) * 1981-04-15 1982-11-30 Campos Vidal Benedicto Colageno i microfibrilar e microcristalino para aplicacao em medicina e farmacia
DE3214337C2 (de) * 1982-04-19 1984-04-26 Serapharm - Michael Stroetmann, 4400 Münster Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung
US4626286A (en) 1983-10-31 1986-12-02 Schmid Laboratories, Inc. Collagen gel and the process of making said gel
US5318524A (en) * 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
FR2668936B1 (fr) * 1990-11-09 1993-01-15 Eberlin Jean Luc Greffon a base de collagene et de colle de fibrine pour la reconstruction osteo-cartilagineuse et son procede de preparation.
CA2107473A1 (en) * 1991-04-08 1992-10-09 Keiji Fujioka Porous solid formulations containing proteinaceous physiologically active substances
AT410754B (de) * 1993-03-31 2003-07-25 Nycomed Austria Gmbh Vorrichtung zum gleichmässigen auftragen einer suspension auf einen kollagenträger
US6177126B1 (en) * 1993-03-31 2001-01-23 Nycomed Arzneimittel Gmbh Process for the production of a material for sealing and healing wounds
JPH0759812A (ja) * 1993-08-27 1995-03-07 Koken Co Ltd 創傷カバ−材及びその製造方法
CN1159206A (zh) * 1994-09-02 1997-09-10 纽约血库公司 由酵母生产和分泌重组血纤维蛋白原
CA2245585A1 (en) * 1996-02-06 1997-08-14 David P. Kosow Composition for sealing wounds
WO1997037694A1 (en) * 1996-04-04 1997-10-16 Immuno Aktiengesellschaft Hemostatic sponge based on collagen
WO1999056797A1 (en) * 1998-05-01 1999-11-11 Zymogenetics, Inc. Fully recombinant tissue sealant compositions
CA2295609C (en) * 1998-05-19 2009-09-29 The American National Red Cross Hemostatic sandwich bandage
JP2002524110A (ja) * 1998-08-10 2002-08-06 フィブロジェン， インコーポレイテッド 血管密封材および創傷被覆材として用いるためのｉ型コラーゲンおよびｉｉｉ型コラーゲン止血性組成物
EP1140235B2 (de) * 1998-12-23 2007-12-19 ZLB Behring GmbH Fibrinklebergranulat und verfahren zu dessen herstellung
DE19922078A1 (de) * 1999-05-15 2000-11-23 Weitzel Kage Doris Gewebekonstrukt für die Transplantationschirurgie

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