MX2010005022A - Anticuerpos que unen celulas dendriticas y epiteliales 205 (dec-205) humanas. - Google Patents
Anticuerpos que unen celulas dendriticas y epiteliales 205 (dec-205) humanas.Info
- Publication number
- MX2010005022A MX2010005022A MX2010005022A MX2010005022A MX2010005022A MX 2010005022 A MX2010005022 A MX 2010005022A MX 2010005022 A MX2010005022 A MX 2010005022A MX 2010005022 A MX2010005022 A MX 2010005022A MX 2010005022 A MX2010005022 A MX 2010005022A
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- dec
- epithelial cell
- bind human
- human dendritic
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
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- C—CHEMISTRY; METALLURGY
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Communicable Diseases (AREA)
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- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
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- Transplantation (AREA)
- Reproductive Health (AREA)
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Abstract
Se describen anticuerpos monoclonales aislados que se unen a células DEC-205 humanas y las composiciones a base de anticuerpos y moléculas relacionadas. También se describen las composiciones farmacéuticas que contienen los anticuerpos, así como métodos terapéuticos y diagnósticos para utilizar los anticuerpos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US225307P | 2007-11-07 | 2007-11-07 | |
US19155108P | 2008-09-10 | 2008-09-10 | |
PCT/US2008/082745 WO2009061996A2 (en) | 2007-11-07 | 2008-11-07 | Antibodies that bind human dendritic and epithelial cell 205 (dec-205) |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010005022A true MX2010005022A (es) | 2010-06-02 |
Family
ID=40257038
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010005022A MX2010005022A (es) | 2007-11-07 | 2008-11-07 | Anticuerpos que unen celulas dendriticas y epiteliales 205 (dec-205) humanas. |
Country Status (18)
Country | Link |
---|---|
US (4) | US8236318B2 (es) |
EP (2) | EP2570137A3 (es) |
JP (3) | JP5701606B2 (es) |
KR (2) | KR101811965B1 (es) |
CN (1) | CN101888856B (es) |
AU (1) | AU2008323848B2 (es) |
BR (1) | BRPI0820270A2 (es) |
CA (1) | CA2704583A1 (es) |
DK (1) | DK2224954T3 (es) |
EA (2) | EA201692127A1 (es) |
ES (1) | ES2445755T3 (es) |
HK (1) | HK1146898A1 (es) |
IL (1) | IL205393A (es) |
MX (1) | MX2010005022A (es) |
NZ (2) | NZ585556A (es) |
SG (2) | SG187482A1 (es) |
WO (1) | WO2009061996A2 (es) |
ZA (1) | ZA201003101B (es) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2933334B1 (en) | 2003-02-18 | 2019-09-18 | Baylor College of Medicine | Induced activation in dendritic cells |
WO2006069198A1 (en) | 2004-12-22 | 2006-06-29 | Cleveland Clinic Foundation | Flagellin related polypeptides and uses thereof |
US8691210B2 (en) * | 2006-10-19 | 2014-04-08 | David M Spencer | Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptors and adaptors thereof |
EP2115002B1 (en) * | 2007-02-02 | 2014-08-20 | Baylor Research Institute | Vaccines based on targeting antigen to dcir expressed an antigen-presenting cells |
WO2008104803A2 (en) | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
MX2010005022A (es) | 2007-11-07 | 2010-06-02 | Celldex Therapeutics Inc | Anticuerpos que unen celulas dendriticas y epiteliales 205 (dec-205) humanas. |
JP5577337B2 (ja) | 2008-08-01 | 2014-08-20 | クリーブランド バイオラブス, インコーポレイテッド | 再灌流傷害を治療するための方法 |
US20100203067A1 (en) | 2008-09-22 | 2010-08-12 | Baylor College Of Medicine | Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters |
BR112012004546A8 (pt) | 2009-08-29 | 2017-12-05 | Abbott Lab | Terapêutica por proteínas ligantes dll4-ligantes |
CN102711824A (zh) * | 2009-09-14 | 2012-10-03 | 贝勒研究院 | 针对朗格汉斯细胞的疫苗 |
CA2813494A1 (en) * | 2009-10-08 | 2011-04-14 | President And Fellows Of Harvard College | Methods and compositions for amelioration of autoimmune disease using fusion proteins of anti-dendritic cell receptor antibody to peptide sequences |
EP2501724B1 (en) | 2009-11-18 | 2015-11-18 | MannKind Corporation | Monoclonal antibodies and diagnostic uses thereof |
CN105037543B (zh) | 2010-03-02 | 2020-11-03 | Abbvie 公司 | 治疗性dll4结合蛋白 |
AU2011239706B2 (en) | 2010-04-13 | 2015-08-20 | Celldex Therapeutics Inc. | Antibodies that bind human CD27 and uses thereof |
JP5975983B2 (ja) * | 2010-04-16 | 2016-08-23 | ベリカム ファーマシューティカルズ, インコーポレイテッド | 固形腫瘍を処置するための方法 |
WO2011146862A1 (en) | 2010-05-21 | 2011-11-24 | Bellicum Pharmaceuticals, Inc. | Methods for inducing selective apoptosis |
DE102010039019B4 (de) | 2010-08-06 | 2014-08-07 | Technische Universität Dresden | Antikörper gegen 6-sulfo LacNAc positive humane dendritische Zellen und deren Verwendung |
WO2012021834A1 (en) * | 2010-08-13 | 2012-02-16 | Baylor Research Institute | Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells |
WO2015095745A1 (en) | 2010-10-20 | 2015-06-25 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
US11207109B2 (en) | 2010-10-20 | 2021-12-28 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
WO2012097012A1 (en) | 2011-01-10 | 2012-07-19 | Cleveland Biolabs, Inc. | Use of toll-like receptor agonist for treating cancer |
PL2663580T3 (pl) * | 2011-01-10 | 2017-08-31 | Ct Atlantic Ltd. | Terapia skojarzona obejmująca przeciwciała wiążące antygen związany z nowotworem |
US20130017151A1 (en) * | 2011-07-11 | 2013-01-17 | Baylor Research Institute | SUBSETS OF ANTIGEN-PRESENTING CELLS (APCs) IN THE HUMAN VAGINA AND THEIR DISTINCT FUNCTIONS |
TW201311895A (zh) * | 2011-07-27 | 2013-03-16 | Baylor Res Inst | 用於胰臟癌之樹突細胞(dc)-疫苗療法 |
MX361874B (es) * | 2012-03-28 | 2018-12-18 | Sanofi Sa | Anticuerpos frente a los ligandos del receptor b1 de bradicinina. |
GB201220010D0 (en) * | 2012-11-07 | 2012-12-19 | Oxford Biotherapeutics Ltd | Therapeutic amd diagnostic target |
CN103044552B (zh) * | 2012-12-11 | 2019-01-29 | 中国医学科学院病原生物学研究所 | 人源化的抗树突状细胞表面dec-205分子的单克隆抗体 |
US9434935B2 (en) | 2013-03-10 | 2016-09-06 | Bellicum Pharmaceuticals, Inc. | Modified caspase polypeptides and uses thereof |
JP6541639B2 (ja) | 2013-03-14 | 2019-07-10 | ベリカム ファーマシューティカルズ, インコーポレイテッド | T細胞増殖をコントロールするための方法 |
US20140302037A1 (en) * | 2013-03-15 | 2014-10-09 | Amgen Inc. | BISPECIFIC-Fc MOLECULES |
EP3569253A1 (en) | 2013-06-05 | 2019-11-20 | Bellicum Pharmaceuticals, Inc. | Methods for inducing partial apoptosis using caspase polypeptides |
MX346878B (es) * | 2013-06-26 | 2017-03-28 | Univ Nac Autónoma De México | Nuevos anticuerpos monoclonales contra el receptor dec-205 de celulas dendriticas de pollo. |
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