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Paghdal et al., 2007 - Google Patents

Sirolimus (rapamycin): from the soil of Easter Island to a bright future

Paghdal et al., 2007

Document ID
5366977795689698575
Author
Paghdal K
Schwartz R
Publication year
Publication venue
Journal of the American Academy of Dermatology

External Links

Snippet

Discovered in fungi in the remote Easter Island, sirolimus (rapamycin) shows potential beyond its obvious antiproliferative and immunosuppressant activity. Studies have demonstrated that sirolimus acts as a vascular endothelial growth factor inhibitor, providing …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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