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Valent et al., 2017 - Google Patents

Midostaurin: a magic bullet that blocks mast cell expansion and activation

Valent et al., 2017

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Document ID
2658060868181019160
Author
Valent P
Akin C
Hartmann K
George T
Sotlar K
Peter B
Gleixner K
Blatt K
Sperr W
Manley P
Hermine O
Kluin-Nelemans H
Arock M
Horny H
Reiter A
Gotlib J
Publication year
Publication venue
Annals of Oncology

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Snippet

Clinically relevant features in patients with systemic mastocytosis (SM) include the cosmetic burden of lesional skin, mediator-related symptoms, and organ damage resulting from mast cell (MC) infiltration in advanced forms of SM. Regardless of the SM variant, expansion of …
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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