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Nghiem et al., 2002 - Google Patents

Tacrolimus and pimecrolimus: from clever prokaryotes to inhibiting calcineurin and treating atopic dermatitis

Nghiem et al., 2002

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Document ID
4955745837054859473
Author
Nghiem P
Pearson G
Langley R
Publication year
Publication venue
Journal of the American Academy of Dermatology

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Snippet

Tacrolimus ointment, a topical inhibitor of the phosphatase calcineurin, has recently been approved in the United States for use in the treatment of atopic dermatitis. It is the first topical immune suppressant that is not one of the hydrocortisone derivatives, important allies in …
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
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