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- research-articleJuly 2022
Role of astrocytes in the self-repairing characteristics of analog neural networks
Neurocomputing (NEUROC), Volume 496, Issue CPages 158–165https://doi.org/10.1016/j.neucom.2022.01.077AbstractSelf-repair is fundamental to biological neural networks. In a neural network with a large number of elements, the probability of failure of each component increases. With the breakdown of each part, there may be a significant ...
- research-articleJuly 2022
Solving subset sum by spiking neural P systems with astrocytes producing calcium
Natural Computing: an international journal (NATC), Volume 22, Issue 1Pages 3–12https://doi.org/10.1007/s11047-022-09900-7AbstractWe consider spiking neural P systems with astrocytes producing calcium that differs from the standard spiking neural P systems in several ways: we have a new type of resources called calcium unit alongside the standard spike, we have a new type of ...
- research-articleJune 2022
Astrocytes mediate analogous memory in a multi-layer neuron–astrocyte network
- Yuliya Tsybina,
- Innokentiy Kastalskiy,
- Mikhail Krivonosov,
- Alexey Zaikin,
- Victor Kazantsev,
- Alexander N. Gorban,
- Susanna Gordleeva
Neural Computing and Applications (NCAA), Volume 34, Issue 11Pages 9147–9160https://doi.org/10.1007/s00521-022-06936-9AbstractModeling the neuronal processes underlying short-term working memory remains the focus of many theoretical studies in neuroscience. In this paper, we propose a mathematical model of a spiking neural network (SNN) which simulates the way a fragment ...
- research-articleSeptember 2021
An investigation on neuron–astrocyte interaction system: network behavior and synchronization
Analog Integrated Circuits and Signal Processing (KLU-ALOG), Volume 108, Issue 3Pages 569–576https://doi.org/10.1007/s10470-020-01735-5AbstractAstrocytes, also described as astroglia, are characteristic star-shaped glial cells in the brain. The important roles of astrocyte such as extracellular regulation, synaptic information regulation, neuronal synchronization and feedback to neural ...
- research-articleMarch 2019
Introducing Astrocytes on a Neuromorphic Processor: Synchronization, Local Plasticity and Edge of Chaos
NICE '19: Proceedings of the 7th Annual Neuro-inspired Computational Elements WorkshopArticle No.: 12, Pages 1–9https://doi.org/10.1145/3320288.3320302While there is still a lot to learn about astrocytes and their neuromodulatory role in the spatial and temporal integration of neuronal activity, their introduction to neuromorphic hardware is timely, facilitating their computational exploration in ...
- articleApril 2018
Circuit modelling of 2-AG indirect pathway via astrocyte as a catalyst for synaptic self repair
Analog Integrated Circuits and Signal Processing (KLU-ALOG), Volume 95, Issue 1Pages 127–139https://doi.org/10.1007/s10470-018-1106-8Recent neurophysiological findings illustrate that the brain detects the faulty synapses and is able to repair them to some extent. It was shown that retrograde signaling via astrocytes leads to modulation of synaptic activity. Specifically, indirect ...
- research-articleJanuary 2018
A neuromorphic real-time VLSI design of Ca2+ dynamic in an astrocyte
Neurocomputing (NEUROC), Volume 272, Issue CPages 197–203https://doi.org/10.1016/j.neucom.2017.06.071Neurophysiological experiments have illustrated that astrocytes, the most abundant subtype of the glial cells, have the potential to dynamically regulate and control synaptic transmissions in neural networks. As these cells are able to provide energy ...
- articleMay 2017
On the role of astrocyte analog circuit in neural frequency adaptation
Neural Computing and Applications (NCAA), Volume 28, Issue 5Pages 1109–1121https://doi.org/10.1007/s00521-015-2112-8In the present study, we develop an analog neuromorphic circuit to implement the astrocyte dynamics. The intracellular calcium waves produced by astrocytes are modeled by a simplified dynamical model which considers the main pathways of neuron---...
- articleJuly 2015
On String Languages Generated by Spiking Neural P Systems with Astrocytes
Fundamenta Informaticae (FUNI), Volume 136, Issue 3Pages 231–240Spiking neural P systems with astrocytes (SNPA systems, for short) are a class of distributed parallel computing devices inspired from the way spikes pass along the synapses between neurons. In this work, we investigate the computational power of SNPA ...
- articleJuly 2015
Reversible Spiking Neural P Systems with Astrocytes
Fundamenta Informaticae (FUNI), Volume 136, Issue 3Pages 219–230Spiking neural P systems with astrocytes (SNPA systems, for short) are a class of distributed parallel computing devices inspired from the way neurons communicate by means of spikes. In this work, we investigate the reversibility in SNPA systems as well ...
- articleJune 2013
Astrocyte- neuron interaction as a mechanism responsible for generation of neural synchrony: a study based on modeling and experiments
Journal of Computational Neuroscience (SPJCN), Volume 34, Issue 3Pages 489–504https://doi.org/10.1007/s10827-012-0432-6Neural synchronization is considered as an important mechanism for information processing. In addition, based on recent neurophysiologic findings, it is believed that astrocytes regulate the synaptic transmission of neuronal networks. Therefore, the ...
- articleNovember 2011
Functional modeling of astrocytes in epilepsy: a feedback system perspective
Neural Computing and Applications (NCAA), Volume 20, Issue 8Pages 1131–1139https://doi.org/10.1007/s00521-010-0479-0Astrocytes, a subtype of glial cells, in the brain provide structural and metabolic supports to the nervous system. They are also active partners in synaptic transmission and neuronal activities. In the present study, a biologically plausible ...
- research-articleSeptember 2011
A neuron-astrocyte transistor-like model for neuromorphic dressed neurons
Experimental evidences on the role of the synaptic glia as an active partner together with the bold synapse in neuronal signaling and dynamics of neural tissue strongly suggest to investigate on a more realistic neuron-glia model for better ...
- articleMarch 2007
Long-term neuronal behavior caused by two synaptic modification mechanisms
Neurocomputing (NEUROC), Volume 70, Issue 7-9Pages 1482–1488https://doi.org/10.1016/j.neucom.2006.05.011We report the first results of simulating the coupling of neuronal, astrocyte, and cerebrovascular activity. It is suggested that the dynamics of the system is different from systems that only include neurons. In the neuron-vascular coupling, ...
- articleJune 2005
Modeling calcium wave oscillations in astrocytes
Calcium wave oscillations are utilized by astrocytes as a method of cellular communication. These waves are dependent on both an intracellular gap junction pathway involving [Ca^+^+]"i and [IP"3]"i and an extracellular pathway involving [ATP]"o and [Glu]...