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A neuron-astrocyte transistor-like model for neuromorphic dressed neurons

Published: 01 September 2011 Publication History

Abstract

Experimental evidences on the role of the synaptic glia as an active partner together with the bold synapse in neuronal signaling and dynamics of neural tissue strongly suggest to investigate on a more realistic neuron-glia model for better understanding human brain processing. Among the glial cells, the astrocytes play a crucial role in the tripartite synapsis, i.e. the dressed neuron. A well-known two-way astrocyte-neuron interaction can be found in the literature, completely revising the purely supportive role for the glia. The aim of this study is to provide a computationally efficient model for neuron-glia interaction. The neuron-glia interactions were simulated by implementing the Li-Rinzel model for an astrocyte and the Izhikevich model for a neuron. Assuming the dressed neuron dynamics similar to the nonlinear input-output characteristics of a bipolar junction transistor, we derived our computationally efficient model. This model may represent the fundamental computational unit for the development of real-time artificial neuron-glia networks opening new perspectives in pattern recognition systems and in brain neurophysiology.

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Cited By

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  • (2021)Astrocytes in modulating subcellular, cellular and intercellular molecular neuronal communicationProceedings of the Eight Annual ACM International Conference on Nanoscale Computing and Communication10.1145/3477206.3477460(1-6)Online publication date: 7-Sep-2021
  • (2018)A neuromorphic real-time VLSI design of Ca2+ dynamic in an astrocyteNeurocomputing10.1016/j.neucom.2017.06.071272:C(197-203)Online publication date: 10-Jan-2018
  • (2015)A novel digital implementation of neuron---astrocyte interactionsJournal of Computational Electronics10.1007/s10825-014-0643-314:1(227-239)Online publication date: 1-Mar-2015
  1. A neuron-astrocyte transistor-like model for neuromorphic dressed neurons

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      Published In

      cover image Neural Networks
      Neural Networks  Volume 24, Issue 7
      September, 2011
      108 pages

      Publisher

      Elsevier Science Ltd.

      United Kingdom

      Publication History

      Published: 01 September 2011

      Author Tags

      1. Astrocyte
      2. Neuron
      3. Neuron-astrocyte interaction model
      4. Synapse

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      View all
      • (2021)Astrocytes in modulating subcellular, cellular and intercellular molecular neuronal communicationProceedings of the Eight Annual ACM International Conference on Nanoscale Computing and Communication10.1145/3477206.3477460(1-6)Online publication date: 7-Sep-2021
      • (2018)A neuromorphic real-time VLSI design of Ca2+ dynamic in an astrocyteNeurocomputing10.1016/j.neucom.2017.06.071272:C(197-203)Online publication date: 10-Jan-2018
      • (2015)A novel digital implementation of neuron---astrocyte interactionsJournal of Computational Electronics10.1007/s10825-014-0643-314:1(227-239)Online publication date: 1-Mar-2015

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