Data from electro-anatomical mapping (EAM) systems are playing an increasingly important role in computational modeling studies for the patient-specific calibration of digital twin models. However, data exported from ...

• An open-source framework for managing electro-anatomical mapping data.
• Access and interrogate mapping data exported from clinical mapping systems.
• Conversion to modeling formats according to the openCARP standard.
• Make the ...

Simulation of cardiac electrophysiology (CEP) is an important research tool that is increasingly being adopted in industrial and clinical applications. Typical workflows for CEP simulation consist of a sequence of ...

• Open-source framework for standardizing cardiac electrophysiology simulations.
• Built upon cardiac electrophysiology modeling community standard software, the openCARP simulator and the carputils framework.
• Simplifies model ...

Mechanoelectric feedback (MEF) in the heart operates through several mechanisms which serve to regulate cardiac function. Stretch activated channels (SACs) in the myocyte membrane open in response to cell lengthening, while tension generation ...

• The role of mechanoelectric feedback mechanisms in the cardiac function is explored.
• An in-silico study using a biventricular canine cardiac geometry is conducted.
• The study uses 3D-0D fluid-electromechanical framework implemented ...

A key factor governing the mechanical performance of the heart is the bidirectional coupling with the vascular system, where alterations in vascular properties modulate the pulsatile load imposed on the heart. Current models of cardiac ...

Image-based computational models of the heart represent a powerful tool to shed new light on the mechanisms underlying physiological and pathological conditions in cardiac function and to improve diagnosis and therapy planning. However,...

• Novel fitting method to find personalized passive material parameters.
• The ...

• We present the openCARP simulation environment as a solution that could foster the needs of large parts of the computational cardiac electrophysiology ...

Background and Objective: Cardiac electrophysiology is a medical specialty with a long and rich tradition of computational modeling. Nevertheless, no community standard for cardiac electrophysiology simulation software has evolved yet. ...

Cardiac output is dependent on the tight coupling between atrial and ventricular function. The study of such interaction mechanisms is hindered by their complexity, and therefore requires a systematic approach. We have developed a four-chamber ...${}^{}$${}^{}$${}^{}$${}^{}$${}^{}$${}^{}$