호모 사피엔스 종의 단백질 코드 유전자
나트륨/수소 교환기 6은 SLC9A6 유전자에 의해 인체 내에서 부호화되는 일체형 막단백질이다.그것은 원래 미토콘드리아 표적 단백질로 생각되었지만, 후속 연구는 혈장막 과 재활용 된 [5] [6] [7] [8]
기능 상실은 크리스티안슨 [9]
「 」를 참조해 주세요. 레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000198689 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000060681 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Numata M, Petrecca K, Lake N, Orlowski J (Mar 1998). "Identification of a mitochondrial Na+/H+ exchanger" . The Journal of Biological Chemistry . 273 (12): 6951–9. doi :10.1074/jbc.273.12.6951 PMID 9507001 . ^ Brett CL, Wei Y, Donowitz M, Rao R (May 2002). "Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria". American Journal of Physiology. Cell Physiology . 282 (5): C1031–41. doi :10.1152/ajpcell.00420.2001 . PMID 11940519 . ^ Deane EC, Ilie AE, Sizdahkhani S, Das Gupta M, Orlowski J, McKinney RA (Jan 2013). "Enhanced recruitment of endosomal Na+/H+ exchanger NHE6 into Dendritic spines of hippocampal pyramidal neurons during NMDA receptor-dependent long-term potentiation" . The Journal of Neuroscience . 33 (2): 595–610. doi :10.1523/JNEUROSCI.2583-12.2013 . PMC 6704919 PMID 23303939 . ^ Ohgaki R, Matsushita M, Kanazawa H, Ogihara S, Hoekstra D, van Ijzendoorn SC (Apr 2010). "The Na+/H+ exchanger NHE6 in the endosomal recycling system is involved in the development of apical bile canalicular surface domains in HepG2 cells" . Molecular Biology of the Cell . 21 (7): 1293–304. doi :10.1091/mbc.E09-09-0767 . PMC 2847532 PMID 20130086 . ^ "Angelman Syndrome - NORD (National Organization for Rare Disorders)" . NORD (National Organization for Rare Disorders) . 2015. Retrieved 28 April 2017 .
추가 정보 Brett CL, Wei Y, Donowitz M, Rao R (May 2002). "Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria". American Journal of Physiology. Cell Physiology . 282 (5): C1031–41. doi :10.1152/ajpcell.00420.2001 . PMID 11940519 . Cheng J, Moyer BD, Milewski M, Loffing J, Ikeda M, Mickle JE, Cutting GR, Li M, Stanton BA, Guggino WB (Feb 2002). "A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression" . The Journal of Biological Chemistry . 277 (5): 3520–9. doi :10.1074/jbc.M110177200 PMID 11707463 . Miyazaki E, Sakaguchi M, Wakabayashi S, Shigekawa M, Mihara K (Dec 2001). "NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell" . The Journal of Biological Chemistry . 276 (52): 49221–7. doi :10.1074/jbc.M106267200 PMID 11641397 . Numata M, Orlowski J (May 2001). "Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network" . The Journal of Biological Chemistry . 276 (20): 17387–94. doi :10.1074/jbc.M101319200 PMID 11279194 . Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (Oct 1996). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain" . DNA Research . 3 (5): 321–9, 341–54. doi :10.1093/dnares/3.5.321 PMID 9039502 . 이 기사에는 미국 국립 의학 도서관 (미국 국립 의학 도서관 )의 공공 도메인 텍스트가 포함되어 있습니다.
그룹별
SLC1 ~ 10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21~30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31~40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41~48
(41): (42): (43): (44): (45): (46): (47): (48):
