Fritz Albert Lipmann

Fritz Albert Lipmann

ForMemRS
Portrait of Fritz Albert Lipmann (1899-1986), Biochemist (2551001689).jpg
Born(1899-06-12)June 12, 1899
Königsberg, German Empire (present-day Kaliningrad, Russia)
DiedJuly 24, 1986(1986-07-24) (aged 87)
Poughkeepsie, New York, U.S.
NationalityGerman-American
Other namesFritz Lippmann
Alma mater
Known forCo-discoverer in 1945 of coenzyme A
Spouse(s)Elfreda M. Hall Lipmann (m. 1931)
Children1
Awards
Scientific career
FieldsBiochemistry
Institutions

Fritz Albert Lipmann (German pronunciation: [fʁɪt͡s ˈalbɛʁt ˈlɪpˌman] (About this soundlisten); June 12, 1899 – July 24, 1986) was a German-American biochemist and a co-discoverer in 1945 of coenzyme A. For this, together with other research on coenzyme A, he was awarded the Nobel Prize in Physiology or Medicine in 1953 (shared with Hans Adolf Krebs).[1]

Early life and education

Lipmann was born in Königsberg, Germany, to a Jewish family. His parents were Gertrud (Lachmanski) and Leopold Lipmann, an attorney.[2]

Lipmann studied medicine at the University of Königsberg, Berlin, and Munich, graduating in Berlin in 1924. He returned to Königsberg to study chemistry under Professor Hans Meerwein. In 1926 he joined Otto Meyerhof at the Kaiser Wilhelm Institute for Biology, Dahlem, Berlin, for his doctoral thesis.[3] After that he followed Meyerhof to Heidelberg to the Kaiser Wilhelm Institute for Medical Research.

Career

From 1939 on, Lipmann lived and worked in the United States. He was a Research Associate in the Department of Biochemistry, Cornell University Medical College, New York from 1939 to 1941. He joined the research staff of the Massachusetts General Hospital in Boston in 1941, first as a Research Associate in the Department of Surgery, then heading his own group in the Biochemical Research Laboratory of the hospital. From 1949 to 1957 he was professor of biological chemistry at Harvard Medical School. From 1957 onwards, he taught and conducted research at Rockefeller University, New York City.

1953년 립만은 "코엔자임 A의 발견과 중간대사에 대한 중요성"으로 노벨 생리의학상 절반의 상을 받았다. 나머지 절반은 한스 아돌프 크렙스가 수상했다.[4] 립만은 1966년에 국가 과학 훈장을 받았다. 그는 현재 팬테신이라고 알려진 공동효소 A의 변종을 발견함으로써 자신의 발견에 더 깊이 뛰어들려고 할 것이다.

립먼은 논문 '인산염 결합 에너지의 메타볼릭 생성과 활용'에서 ATP와 같이 에너지가 풍부한 생체분자 속에 에너지가 풍부한 인산염을 나타내기 위해 구체적인 스퀴글 지정(~)을 소개했다.[5] 그는 자신의 작품에 대해 "생합성 분야에서 우리는 간소화로 이어지는 진보를 보여주는 보기 드문 사례가 있다"[6]고 말했다.

사생활

1953년 스톡홀름에서 아내와 함께한 립만

1931년 립만은 엘프레다 M과 결혼했다. 홀,[2] 아들 하나가 있었어 립만은 1986년 뉴욕에서 사망했다.[7] 그의 미망인은 2008년 101세의 나이로 세상을 떠났다.

참고 항목

참조

  1. ^ Jencks, W. P.; Wolfenden, R. V. (2000). "Fritz Albert Lipmann. 12 June 1899 -- 24 July 1986: Elected For.Mem.R.S. 1962". Biographical Memoirs of Fellows of the Royal Society. 46: 333. doi:10.1098/rsbm.1999.0088.
  2. ^ a b "Fritz Lipmann – Biographical". Nobel Prize.
  3. ^ Krebs, Hans A.; Lipmann, Fritz (1974). "Dahlem in the Late Nineteen Twenties". In Richter, Dietmar (ed.). Lipmann Symposium. Energy transformation in biological systems. Berlin: Walter De Gruyter. pp. 7–27.
  4. ^ "The Nobel Prize in Physiology or Medicine 1953". NobelPrize.org. Retrieved August 7, 2019.
  5. ^ "Fritz Lipmann Facts". biography.yourdictionary.com. Retrieved August 7, 2019.
  6. ^ The Rockefeller University (January 1, 1950). "Fritz Lipmann, 1948". Harvey Society Lectures.
  7. ^ 프리츠 A. LIPMAN, 생화학자, 죽는다 뉴욕타임스(1986년 8월 16일)

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