Airway Clearance
Airway Clearance
Airway Clearance
Contents
• Functional anatomy of the Respiratory tract
• Mucus and its role in airway clearance
• Mechanism of an effective cough
• Airway clearance techniques
• Conventional
• Advanced
• literature
3
Nose
• Nose is composed of bony and cartilagenious
parts.
• The upper 1/3rd is primarily bony where as lower
2/3rd is cartilagenious
• Nasal cavity is divided into right and left halves
by nasal septum
• Nasal cavity extends from the nostrils to the
nasopharynx posteriorly
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Oral cavity
9
Oral cavity
• Anterior roof is called the hard palate and is
formed by maxillary bone
• Posterior portion is called soft palate
• Uvula
• Walls are formed by cheeks
• Floor by tongue
10
Pharynx
• Space behind oral and nasal cavity
• Divided into naso, oro and laryngopharynx
12
Larynx
• Lies between upper and lower airways in
anterior portion of the neck at the level of 4,5,6th
cervical vertebrae
Trachea
• Adult trachea is approx 12 cms long and 2-3cms
in diameter
• Cilia- sparse
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• Diameter approx 1 mm
Respiratory bronchioles
(Generation 17th – 19th)
• Transitional zone
Alveolar ducts
(generation 20th – 22nd )
Mucus
• Mucus is produced in the goblet and submucosal
glands containing 95% water, 2% glycoproteins,
1% carbohydrate, trace amt of lipids and RNA
Mucociliary escalator
Mucociliary clearance
Normal clearance requires:
1. Patent airway
2. Functional mucociliary escalator
3. Effective cough
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Mechanism of Cough
• 4 stages
• Building up of
Stage 3 Intrathoracic and intra
Glottal opening and expulsion
Stage4 abdominal pressure
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• Stimulates sensory
fibres
• Impulses transmitted to
the medulla
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• Afferent impulses
received
• Reflex stimulation of
respiratory muscles
• Initiation of inspiration
• Range 1-2L
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• Airway obstruction
• Mucus plugging
• Atelectasis
• Impaired gas exchange
• Increased work of breathing
• Infection
49
Indications
• Cystic fibrosis
Bronchiectasis
• A breakdown of the elastic tissue in bronchial wall
severe dilatation
• Inflamed mucosa and copious purulent secretions are
present
• Airway clearance has shown benefits in mobilisation
of sputum
Atelectasis
• Collapse of alveolar segments due to retained
pulmonary secretions resulting in mucus plugging
• In cases of thoracic or abdominal surgeries under GA
• ACT’s are indicated due to mucus plugging
Mechanical ventilation
• Patients who are on ventilator support or comatose
are at risk for atelectasis
• Airway clearance is a standard practice in the
management of patients on mechanical ventilation
Crane, 1995
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Conventional Advanced
1.) Positive expiratory
techniques
1.) Postural drainage
2.) Mechanical
Insufflation-exsufflation
2.) Forced expiratory
techniques
3.) HFCWO
3.) ACBT
4.) Intra pulmonary
percussive ventillation
4.) Autogenic drainage
5.) Acoustic airway
clearance
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Postural drainage
• Passive technique in which patient is placed in
positions that allows gravity to assist with the drainage
of secretions in the bronchopulmonary tree
Indication
• Cystic fibrosis
• Bronchiectasis, COPD
• Pneumonia
• Presence of foreign body in airway
• Prevent accumulation of secretions – prolong bed rest
or after general anesthesia
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Contra-
indications
Advantages Disadvantages
• Easy to learn Adherence to PD
Turning
• Rotation of the body around a longitudinal axis
Percussions
• Chest clapping
percussion
• Not to percuss on breast tissue or bony prominences
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Advantages
Disadvantages
• Not tolerated in post operative patients
• Injury to caregiver
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• Frequency of vibration – 12 to 20 Hz
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• Frequency of shaking – 2 Hz
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Advantages
• Enhances mobilization of secretions
• Better tolerated in post surgical patients
• Stretch on the muscle during expiration may
encourage deeper inspiration
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Breathing control
Thoracic expansion exercises
FET
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Rationale:
• Breathing control phase:
• This phase between the other phases is essential
to prevent bronchospasm
Advantages
• Decrease in oxygen saturation in PD and percussions
has been prevented by use of ACBT
• Easily tolerable
87
Disadvantages
• Requires caregiver to assist the patient with the
technique
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Autogenic drainage
• Introduced by Chevaillier in 1976
• Self drainage
• 3 phases
• 3 Phases
Unsticki Collectin
ng Phase g Phase
Evacuati
ng Phase
90
• No equipments required
Advantages Disadvantages
Attention and
Children above 12 years of age can
perform independently
concentration
Doesn’t require PD position Unco-operative
patients
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Low-pressure PEP
Resistance adjusted so as to
achieve pressure between 10 to
20 cm of water during active
expiration
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PEP devices
• Acapella
• TheraPEP
• Flutter
• Quake
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Acapella
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Thera-PEP
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• Mouth piece
Flutter
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Quake
• Mouth piece integrated with the outer part
• Wider range
oscillation
frequencies
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Mechanical Insufflation-Exsufflation
• This device delivers a positive breath of 30 to 50
cm of H2O over a period of 1 to 3 secs via a face
mask or tracheal airway
It consists of
Air pulse generator
Inflatable vest
Advantages
• Independently used
• No positioning required
Disadvantages
• Cost of the equipment
114
- Downs AM 2004
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Advantages:
• Comfortable and independence
• Home use
Disadvantages:
• Not tolerated well by young patients
Advantages
• Specific areas of the lug can be targeted
Disadvantages
• expensive
128
• Skills of therapists
• Fatigue
severity
• Costs
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Adjuncts to ACT
• Antibiotics
• Bronchodilators
• Anti-inflammatory drugs
• Mucolytics
• Nutrition
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Impaired
airway
clearance
Mucus Mucus
retention plugging
ACT
Lung damage
Increased mucus
Lung
production infection
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• Level of significance – 1a
• Osadnik CR et al
• Cochrane Database of Systematic Reviews 2012, Issue 3
133
Objective :
Primary
To determine whether ACTs have beneficial effects on
exacerbations, hospitalisation and HRQoL in people with
AECOPD and stable COPD.
Secondary
To assess whether:
• airway clearance techniques are effective in both
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Studies included
Randomized parallel trials and randomized cross-
over trials which compared an ACT to no treatment,
cough or sham ACT
Participants
COPD, emphysema or chronic bronchitis
135
Iterventions
Conventional techniques, breathing exercises, and
PEP or mechanical devices
Outcomes
Primary :
1. Rate of, or time to, AECOPD, defined according to the
investigators’ definition.
2. Respiratory-related hospitalisations and resource
utilisation
136
Results
• 13 randomised controlled trials (RCT) on 629
participants and 15 randomised cross-over trials
(RXT) on 278 participants.
Conclusion
• In AECOPD, ACT use is associated with a reduced
need and duration of ventilatory assistance
• Small reduction in length of hospital stay
• No effect of ACTs on future exacerbations or
hospitalisations was evident
139
• Lee AL et al
Studies included:
• Randomised controlled parallel and cross-over
trials that compared an ACT to no treatment,
sham ACT or directed coughing in participants
with bronchiectasis.
• Participants :
• Adults and children with Bronchiectasis
144
Interventions:
• Conventional techniques, breathing exercises,
and PEP or mechanical devices
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Outcomes:
• Primary outcome:
• Incidence of hospitalization
• Secondary outcome:
• Pulmonary function
• Gas exchange
• Symptoms
• Days of antibiotics
• Sputum clearance and expectoration
• Exercise tolerance
• Mortality (all-cause)
147
Results :
• 5 studies were included consisting of 51
participants
Conclusion:
• ACTs are safe for adult as well as Children with
stable bronchiectasis and there is improvement
in sputum production, select measures of lung
function and HRQOL
• Level of evidence – 1 b
• Methodology:
30 clinically stable male COPD patients were
randomly assigned to AD or the ACBT treatment
for a 20-day treatment period.
Outcome measure:
Pulmonary function tests, arterial blood gases,
6MWT, and a modified Borg Scale before, and
immediately after the walking test.
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• Result:
• AD improved FVC, FEV in 1 sec, PEFR , FEV 25
to 75%, chronic hypercapnia, arterial
oxygenation, exercise performance, and dyspnea
perception during exercise.
Conclusion
• Daiwai M et al , 2009
Study population:
Patients who had an episode of elevated ICP were
selected
Control group: 15 pts did not receive chest
percussions
Outcome measures
Heart rate, Respiratory rate, Blood pressure, Body
temperature, ICP, cerebral perfusion pressure, and
oxygen saturation, CSF drainage
Results :
• Intracranial pressures for the control group
before, during, and after the study period did not
differ significantly from pressures in the
intervention group, safe to perform
157
References:
• Cardiovascular and Pulmonary Physical therapy,
Donna Frownfelter , Elizabeth Dean
edition
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