Special Issue - 2021 International Journal of Engineering Research & Technology (IJERT)

ISSN: 2278-0181
NCCDS - 2021 Conference Proceedings

Anti-Diabetic Ayurvedic Fruit -Noni

Noni Which Helps Mankind
Amareshwar Karatagi 1 Priyanka Karatagi2
School of Electronics and Communication MSc in Bio.Technology, PGD in CR & PHV
REVA University KSOU, Sysplex Bio & Clinical Solutions
Bangalore, India Bangalore, India

Vasudha.R3
B.com
Bangalore, India

Abstract—Morinda citrifolia which is commercially familiar mankind. especially the fruit of noni has nutritional and
with the name of noni, commonly found in Polynesia and healing morals, noni is also used in industries as natural
utilizes more than 2000 years. Morinda. citrifolia is a teeny preservatives, chemical reagents [2]. In olden dyes, noni was
bushy tree 6cmn tall which grows fruit with yellow and it used to make some dyes, for example, red and yellow. Noni
belongs to the coffee family of Rubiaceae. noni has its own
fruits are abundantly used in the preparation of juice for
therapeutic and nutritional values. Noni is also used in the
preparation of chemical reagents, dyes, and preservatives. diabetics and also curing flu, cold, high blood pressure, fear,
Noni has a very effective healing power to heal a cold, flu, and and sadness. not only the fruit of a noni plant the timber is
high blood pressure. Noni is used in the manufacturing of used in the building light constructions. cosmetics are also
cosmetics. noni also has its application in the cooking field like made from the leaves and fruit of the noni. Noni is also used
in the preparation of jam, jellies, sauce, and curries. Noni has in the treatment of burns, anti-aging, stomach ulcers, stroke,
its curing benefits like anti-inflammatory, anti-bacterial, anti- and indigestion. noni helps in the preparation of jam, sauces,
tumor, anti-viral, and also in the reduction of cholesterol. The and curries.
root of a noni plant can be used in the curing of swelling. Every
part of noni is very effectively used in the field of medicine.
Noni leaves have a strong antidiabetic and effective II. LITERATURE SURVEY
antioxidant. noni is mainly used in the treatment of Diabetes In an authoritative CRC guide, James Duke reported 23
mellitus commonly known as Diabetes. The commonly seen 3 distinct phytochemicals present in Noni, as well as 5
types of diabetes are type 1, type 2, and Gestational diabetes.
vitamins and 3 minerals.[3]
noni is very effectively used in the treatment of type 2 diabetes
which is a lifetime disease, cells fail to respond to insulin When Polynesians came from Southeast Asia 2000 years
[insulin resistance ].In this paper, we are going to analyze the ago, they are said to have taken numerous plants with them
phytochemical properties and antidiabetic activity of the noni as food and medicine[4].
fruit, leaf, and leaves that are available in the market. The main Noni was the second most popular plant utilized in herbal
objective is a quantitative analysis of phytochemical medicines to cure many common ailments and maintain
compounds present in noni. fruit and juice which is available general good health, out of the 12 most common medicinal
in the local market. The methods and materials used are plants they brought.[5]
collection and extraction of the noni fruit, leaves, and juice; the Noni, also known as Indian Mulberry, Ba Ji Tian, Nono, or
phytochemical components are found by phytochemical
Nono, is the popular name for Morinda citrifolia L. In many
screening c done by Nweze et.al [2004]and Senthilkumar and
Reetha[2009]. The anti dietary assay was also carried out by 2 civilizations, Nonu, Cheese Fruit, and Nhau are used. All
tests namely [1]inhibition assay of alpha-amylase [2]Glucose around the globe, It's been said that it has a wide variety of
diffusion assay. Noni[Morinda citrifolia] can be implemented health advantages for cancer, infection, and other diseases
as a healthy daily supplement that offers various benefits. Noni Arthritis, diabetes, asthma, hypertension, and pain are all
is also recommended for diabetic patients for treatment. conditions that affect people.[6]
The Polynesians used the whole Noni plant for medical
Keywords—Noni: Morinda citrifolia, diabetes, medicinal plant, purposes and as a dye for some of thei
antioxidant, photochemical r traditional clothing. The roots, stems, bark, leaves, flowers,
I. INTRODUCTION and other parts of the plant. The fruits of the Noni plant are
Noni is scientifically known as morinda citrifolia; it is found used in almost 40 herbal treatments that are recognized and
in the pacific island, Australia, the southeast, and India and documented.[7]
absorbed over 2000 years.m.citrifolia is a yellow fruit- The roots were also used to make a yellow or red dye for
bearing plant with a height of 6m.[1]. Marinda citrifolia tapa textiles and fala (mats), and the fruit was consumed for
belongs to the coffee family rubiaceae[nelson,2006]. Each health and nutrition. Noni was utilized by many heroes and
part of Morinda citrifolia has its beneficial value for heroines in Polynesian legends to help them escape hunger.

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Special Issue - 2021 International Journal of Engineering Research & Technology (IJERT)
ISSN: 2278-0181
NCCDS - 2021 Conference Proceedings

There is a legend about Kamapua'a, the pig deity, who fell 1. AIM
in love with Pele, the volcano goddess.“I have seen the To analyze the physicochemical properties and anti-diabetic
woman gathering Noni/scratching Noni/pounding Noni,” he activity of M.citrifolia leaf and fruit and extract in
teased Pele. According to legend, the song alluded to Pele's commercially available noni juice.
eyes becoming by the application of Noni leaves to his 2. OBJECTIVE
body.[8] To study the antidiabetic activities in the extraction of noni
The fruit of the Morinda citrifolia has a long history of usage fruit, leaf, and juice
as a meal in tropical places all over the world. Written To study the qualitative analysis of phytochemicals present
evidence of this fruit’s use as a food source dates back to in commercial noni fruit and juice extract.
before the nineteenth century. The fruit was consumed in
Tahiti, according to Captain James Cook of the British Navy 3. MATERIALS AND METHODS
in crimson, and she got so enraged that she fought him.
According to a Tongan legend, the deity Maui was brought II.Collection of noni fruit
back to life in the late 1700s [9]. The fresh fruits are collected from plants and washed with
distilled water, wiped, and stored in a closed container.
squeeze the fruit and collect the extract and use it
III. METHODOLOGY as a sample.
Noni a well-known Indian mulberry or Indian noni. The III.Collection of commercial noni juice
scientific name of the noni is Morinda Citrifolia found in The commercially available fruit juice of noni from the
Polynesians. It is an evergreen shrub that bears fruits and market
flowers for a whole year.M.citrifolia belongs to the coffee IV.Processing of leaf samples
family Rubiaceae. Each part of noni is very essential The fresh leaves were collected and washed with normal
.M.citrifolia is a folk remedy for many diseases. Fruit of noni tap water and rinsed with distilled water. The
has very many essential therapeutic values like washed plant material was shade dried and crushed into
antiviral,anti-bacterial, anti-tumor, anti-inflammatory, a mechanical blender. powdered plant
reducing the cholesterol level from the extraction of noni material is used for aqueous, chloroform,
plant root swelling can be reduced. The leaves of the noni ethanol, and acetone extracts.
have strong antidiabetic and a very strong antioxidant V.Preparations of leaf extracts
activity. leaves are directly applied to the wounds for better
healing. In the noni plant, about 160 phytochemical
compounds are found. Diabetes is also known as diabetes 1g of powdered leaf material is taken
mellitus which is relevant to chronic metabolic disorder.
.most commonly can see 3 types of diabetics
● Type 1 diabetes.
● Type 2 diabetes.
● Gestational diabetes. Dissolved in 10 ml of sterile distilled
water,chloroform,acetone,ethanol,sepearatly.

Kept it in the shaker for 24hrs

Contents were filtered and allow for evaporation

A. Fig:01, Noni Fruit

Final sample was weighed and dissolved in the
In type 2 diabetes the cells fail to respond to insulin (insulin required volume of respective solvents.
resistance does not produce insulin).so the receptor present
on the layer of the muscles and the liver will reduce their Fig:02 flow chart of preparation of leaf extracts
capacity to respond to the glucose. In this case, noni
extraction is very useful to treat type 2 diabetes 1 gram of powdered leaf material was dissolved in 10ml of
sterile distilled water, chloroform, acetone, ethanol
separately and kept in the shaker for 24 hours. The
contents were filtered and allowed for evaporation.

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 Special Issue - 2021 International Journal of Engineering Research & Technology (IJERT)
ISSN: 2278-0181
NCCDS - 2021 Conference Proceedings

The final sample was weighed and 5. SUMMARY AND CONCLUSION

dissolved in the required volume of respective ● The recent approval of noni fruit puree as a novel
solvents. food ingredient, as well as the growing popularity of this
VI.Screening For Phytochemical Constituents fruit in health beverages, will greatly increase its use in
The Phytochemical screening of the sample was carried out foodstuffs and consequently, its consumption among the
as described by Nweze et al.,(2004) and Senthilkumar and general population.
Reetha (2009).The samples(fruit flavonoids, Phyto steroids ● The proximate nutritional, vitamin, mineral, and
phytosterols and steroids, anthocyanin and betacyanin, amino acid contents were determined. The processed noni
phenols and tannins, saponins, glycosides, and proteins. fruit puree is a potential dietary source of vitamin C, vitamin
A, niacin, manganese, and selenium. The major
VII.ANTIDIABETIC ASSAY phytochemicals in the puree are iridoids, especially diacetyl
The antidiabetic assay was carried out using the following asperuloside acid, which are present in higher
tests concentrations than vitamin C (Brette et al., 2018).
1. Inhibition assay for α-amylase activity ● The present study analyzed the phytochemical
2. Glucose diffusion assay constituents and antidiabetic activity of noni leaf extracts,
noni fruit extract, and commercial noni juice.
VIII.DISCUSSION AND RESULTS ● We found that the extracts of noni at minimum
Phytochemical screening concentration could be exploited in the treatment of type 2
The present study reveals that the noni fruit extracts diabetes mellitus and can be used as a dietary source as they
contain carbohydrates, tannis, saponins, alkaloids, proteins, possess essential phytochemicals. Although the effects of
steroids, and phytosterols whereas commercial noni juice M.citrifolia extract have been established in vitro, the results
was found to contain only carbohydrates and tannin. indicate that M.citrifolia has the potential to be used as a
crude drug and a dietary health supplement.
IV.ANTIDIABETIC ACTIVITY ● Further studies on antidiabetic activity have to be
Inhibition assay of alpha-amylase activity carried out to confirm the test results.
The results of leaf extraction in different solvents showed
variations in glucose utilization. The lower value of 13% 6. REFERENCE
enzyme activity was found in ethanol extract of leaf samples. [1] Edipo.S Almeida , Debora de oliveira and Dachamin Hortza on

•
At all concentrations, noni fruit extract showed maximum “Properties And Applications of Morinda Citrifolia [Noni]
enzyme activity with the highest value of 84% at 1ml [2] ReemAbou AssiaYusridaDarwisaIbrahim M.Abdulbaqi Arshad
A.khanaLimVuanghaobM.H.LaghariaSchool of Pharmaceutical
concentration of fruit extract. Sciences, Universiti Sains Malaysia, 11800 Pulau Penang, Malaysia

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Ethanol extract of noni leaf showed minimum enzyme Integrative Medicine Cluster, Advanced Medical and Dental
activity compared to control and noni fruit extract at low Institute, Universiti Sains Malaysia, Bertam 13200 Kepala Batas,
concentrations. there was a dose-dependent increase in Penang, Malaysia
[3] Duke JA. Handbook of phytochemicals. Boca Raton, FL:
percentage activity of an α-amylase enzyme. CRCPublishing; 1992.

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The ethanol extract of the plant exhibited low amylase [4] Tabrah FL, Eveleth BM. Evaluation of the effectiveness of ancient
activity( 13%-68%) than control, noni fruit extract, and Hawaiian medicine. Hawaii Med J 1966; 25: 223-30
commercial noni juice. [5] Krauss B. Plants in Hawaiian culture. Honolulu: University of Hawaii
Press; 1993. p103, p252.
[6] Whistler W. Tongan herbal medicine. Isle Botanica, Honolulu,
We suggest that you use a text box to insert a graphic (which is Hawaii, 1992. p 89-90
ideally a 300 dpi resolution TIFF or EPS file with all fonts [7] Bruggnecate JT. Native plants can heal your wounds. Honolulu Star-
embedded) because this method is somewhat more stable than Bulletin Local News 1992 Feb 2.
directly inserting a picture. [8] Neal M. Gardens of Hawaii. Honolulu, Hawaii: Bishop Museum
Press; 1965. p 804.
To have non-visible rules on your frame, use the MSWord
[9] Cheeseman TF. The flora of rarotonga, the chief island of the cook
“Format” pull-down menu, select Text Box > Colors and Lines to group. v 6. London: Linnean Soc;1903. p 261-313
choose No Fill and No Line.

•activity.
Acarbose as control shows (23%-77%) of α-amylase

•highα- amylase enzyme inhibition compared with other

Hence the ethanol extract of noni leaf was found to have

extracts of noni.

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