SAFETY DATA SHEET Version 6.

0
Revision Date 29.08.2019
Print Date 04.10.2019

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Iron(III) chloride
Product Number : 451649
Brand : Aldrich
CAS-No. : 7705-08-0
1.2 Other means of identification
Ferric chloride
1.3 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : For R&D use only. Not for pharmaceutical, household or other
uses.
1.4 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich (M) Sdn. Bhd.
A-07-11 Empire Office, Empire Subang
47500 SUBANG JAYA, SELANGOR DARUL EHSAN
MALAYSIA
Telephone : +60 603 563-53321
Fax : +60 603 563-54116
1.5 Emergency telephone number
Emergency Phone # : +62 08001401253

SECTION 2: Hazards identification

2.1 GHS Classification

Classification according to CLASS regulations 2013
Acute toxicity, Oral (Category 4), H302
Skin corrosion/irritation (Category 2), H315
Serious eye damage/eye irritation (Category 1), H318
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 GHS Label elements, including precautionary statements
Labelling according to CLASS regulations 2013
Pictogram

Signal word Danger

Hazard statement(s)
H302 Harmful if swallowed.
H315 Causes skin irritation.
H318 Causes serious eye damage.
Aldrich- 451649 Page 1 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
 Precautionary statement(s)
Prevention
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/ eye protection/ face protection.
Response
P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if
you feel unwell. Rinse mouth.
P305 + P351 + P338 + IF IN EYES: Rinse cautiously with water for several minutes.
P310 Remove contact lenses, if present and easy to do. Continue
rinsing. Immediately call a POISON CENTER or doctor/
physician.
Disposal
P501 Dispose of contents/ container to an approved waste disposal
plant.
2.3 Other hazards - none

SECTION 3: Composition/information on ingredients

Substance / Mixture : Substance

3.1 Substances
Synonyms : Ferric chloride

Formula : Cl3Fe
Molecular weight : 162.20 g/mol
CAS-No. : 7705-08-0
EC-No. : 231-729-4
Hazardous components
Component Classification Concentration
Iron trichloride
Acute Tox. 4; 2; 1; <= 100 %
H302, H315, H318
For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

Aldrich- 451649 Page 2 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
 If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult
a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Hydrogen chloride gas, Iron oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist
or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing
dust.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Discharge into the environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in
suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store under inert gas. Keep container tightly closed in a dry and well-ventilated place.
Keep in a dry place.

Aldrich- 451649 Page 3 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Components with workplace control parameters
Component CAS-No. Value Control Basis
parameters
Iron trichloride 7705-08-0 TWA 1 mg/m3 Malaysia. Occupational Safety
and Health (Use and Standards
of Exposure of Chemicals
Hazardous to Health)
Regulations 2000.
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands
before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU)
2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail
sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which
differ from EN 374, contact the supplier of the CE approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist
and safety officer familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
scenario.

Aldrich- 451649 Page 4 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
 Body Protection
Complete suit protecting against chemicals, The type of protective equipment must
be selected according to the concentration and amount of the dangerous substance
at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-
face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as
a backup to engineering controls. If the respirator is the sole means of protection,
use a full-face supplied air respirator. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN
(EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Discharge into the environment must be avoided.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

a) Appearance Form: powder
b) Odour pungent
c) Odour Threshold No data available
d) pH No data available
e) Melting Melting point/range: 304 °C
point/freezing point
f) Initial boiling point 316 °C
and boiling range
g) Flash point Not applicable
h) Evaporation rate No data available
i) Flammability (solid, No data available
gas)
j) Upper/lower No data available
flammability or
explosive limits
k) Vapour pressure < 1 hPa at 20 °C
1 hPa at 194 °C
l) Vapour density 5.60 - (Air = 1.0)
m) Relative density 2.800 g/cm3
n) Water solubility No data available
o) Partition coefficient: No data available
n-octanol/water
p) Auto-ignition No data available
temperature
q) Decomposition No data available
temperature

Aldrich- 451649 Page 5 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
 r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Relative vapour 5.60 - (Air = 1.0)
density

SECTION 10: Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Strong oxidizing agents, Potassium, Alkali metals, Bases, Exothermic in contact with water,
Forms shock-sensitive mixtures with certain other materials.
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Hydrogen chloride gas,
Iron oxides
Other decomposition products - No data available
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity
LD50 Oral - Mouse - female - 1,300 mg/kg
Remarks: (ECHA)
LD50 Dermal - Rat - male and female - > 2,000 mg/kg
(OECD Test Guideline 402)
Remarks: (in analogy to similar products)
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 4 h
(OECD Test Guideline 404)
Remarks: (in analogy to similar products)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye damage.
(OECD Test Guideline 405)
Remarks: (in analogy to similar products)
Respiratory or skin sensitisation
Local lymph node assay (LLNA) - Mouse

Aldrich- 451649 Page 6 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
 Result: negative
(OECD Test Guideline 429)
Remarks: (in analogy to similar products)
Germ cell mutagenicity
In vitro mammalian cell gene mutation test
mouse lymphoma cells
Result: negative
Mutagenicity (mammal cell test): micronucleus.
Chinese hamster lung cells
Result: negative

Mouse - female
Result: negative
(ECHA)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
Repeated dose toxicity - Rat - male - Oral - 98 d - No observed adverse effect level - 277
mg/kg
RTECS: LJ9100000

spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the
bronchi, pneumonitis, pulmonary edema, Overdose of iron compounds may have a
corrosive effect on the gastrointestinal mucosa and be followed by necrosis, perforation,
and stricture formation. Several hours may elapse before symptoms that can include
epigastric pain, diarrhea, vomiting, nausea, and hematemesis occur. After apparent
recovery a person may experience metabolic acidosis, convulsions, and coma hours or days
later. Further complications may develop leading to acute liver necrosis that can result in
death due to hepatic coma.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.

SECTION 12: Ecological information

12.1 Toxicity
No data available
Toxicity to daphnia Immobilization EC50 - Daphnia magna (Water flea) - 9.6 mg/l - 48 h
and other aquatic (OECD Test Guideline 202)
invertebrates

Aldrich- 451649 Page 7 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
 Toxicity to algae ErC50 - Pseudokirchneriella subcapitata (green algae) - 6.9 mg/l -
72 h
(OECD Test Guideline 201)
NOEC - Pseudokirchneriella subcapitata (green algae) - 2.4 mg/l -
72 h
(OECD Test Guideline 201)
12.2 Persistence and degradability
Biodegradability Result: - Readily biodegradable.
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Other adverse effects
Toxic to aquatic life.
No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or
mix the material with a combustible solvent and burn in a chemical incinerator equipped
with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information

14.1 UN number
ADR/RID: 1773 IMDG: 1773 IATA-DGR: 1773
14.2 UN proper shipping name
ADR/RID: FERRIC CHLORIDE, ANHYDROUS
IMDG: FERRIC CHLORIDE, ANHYDROUS
IATA-DGR: Ferric chloride, anhydrous
14.3 Transport hazard class(es)
ADR/RID: 8 IMDG: 8 IATA-DGR: 8
14.4 Packaging group
ADR/RID: III IMDG: III IATA-DGR: III
14.5 Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA-DGR: no
14.6 Special precautions for user
None

Aldrich- 451649 Page 8 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada
14.7 Incompatible materials
Strong oxidizing agents, Potassium, Alkali metals, Bases, Exothermic in contact with water,
Forms shock-sensitive mixtures with certain other materials.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the

substance or mixture
Notification status
AICS: On the inventory, or in compliance with the inventory
DSL: All components of this product are on the Canadian DSL
ENCS: On the inventory, or in compliance with the inventory
ISHL: On the inventory, or in compliance with the inventory
KECI: On the inventory, or in compliance with the inventory
NZIoC: On the inventory, or in compliance with the inventory
PICCS: On the inventory, or in compliance with the inventory

SECTION 16: Other information

Full text of H-Statements referred to under sections 2 and 3.

H302 Harmful if swallowed.
H315 Causes skin irritation.
H318 Causes serious eye damage.
Further information
Copyright 2018 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.

The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the
information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact mlsbranding@sial.com.

Aldrich- 451649 Page 9 of 9

The life science business of Merck operates as MilliporeSigma in

the US and Canada