The film is based on the real-life story of Amanda Knox who was accused of the murder of Meredith Kercher in 2007.
The title "The Face of an Angel" is inspired by the book "Angel Face", drawn from crime coverage by Newsweek/Daily Beast writer Barbie Latza Nadeau.
Both Daniel Brühl and Cara Delevigne have appeared as villains in superhero films with Brühl appearing in the Marvel Cinematic Universe film Captain America: Civil War (2016) as Zemo while Delevigne appears in the DC Extended Universe film Suicide Squad (2016) as June Moone / Enchantress.
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