Osmosis Jones

2001
PG
1h 35m

IMDb RATING

6.3/10

40K

YOUR RATING

POPULARITY

Play trailer1:10

Buddy Cop Dark Comedy Hand-Drawn Animation High-Concept Comedy Police Procedural Slapstick Action Adventure Animation Comedy

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

Directors
- Bobby Farrelly
- Peter Farrelly
Writer
- Marc Hyman
Stars

See production info at IMDbPro

IMDb RATING

6.3/10

40K

YOUR RATING

POPULARITY

4,986

766

Directors
- Bobby Farrelly
- Peter Farrelly
Writer
- Marc Hyman
Stars

See production info at IMDbPro

Awards
- 1 win & 8 nominations total

Thrax
(voice)

Chris Rock

Osmosis Jones
(voice)

David Hyde Pierce

Drix
(voice)

Brandy Norwood

Leah
(voice)

William Shatner

Mayor Phlegmming
(voice)

Ron Howard

Tom Colonic
(voice)

Kid Rock

Kidney Rock
(voice)

Kenny Olson

Kidney Rock
(voice)

Jason Krause

Kidney Rock
(voice)

Joe C.

Kidney Rock
(voice)

Stefanie Eulinberg

Kidney Rock
(voice)

Jimmie Bones

Kidney Rock
(voice)

Uncle Kracker

Kidney Rock
(voice)

Jonathan Adams

Additional Character Voice
(voice)

Carlos Alazraqui

Additional Character Voice
(voice)

Keith Anthony

Additional Character Voice
(voice)

Eddie Barth

Additional Character Voice
(voice)

Sally Brooks

Additional Character Voice
(voice)
(as Sally Ann Brooks)

Directors
- Bobby Farrelly
- Peter Farrelly
Writer
- Marc Hyman
All cast & crew
Production, box office & more at IMDbPro

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Storyline

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Did you know

Edit

Trivia
Bill Murray's character mentions a "National Chicken Wing Festival" in Buffalo, New York. While the festival did not exist during the filming of the movie, this mention caused organizers to create an annual festival in Buffalo. The festival has been held annually on Labor Day weekend since 2002.

Goofs
Chill was sent into Frank as a flu vaccine. While he could have been a live, weakened virus had he been administered via LAIV (FluMist), this variety of the vaccine was not introduced until 2 years after the film was released. So Chill would have had to come from an injection, meaning he would be a dead virus.

Quotes
Thrax: Ebola? Let me tell you something about Ebola, baby. Ebola is a case of DANDRUFF compared to me!

Crazy credits
The title appears as bubbles, which then pop after 5 seconds.

Alternate versions
On some streaming services, the score plays on the soundtrack as opposed to a pop song during the opening scene.

Connections
Edited into Ozzy & Drix: Home with Hector (2002)

Soundtracks
Turn It Out
Written by Kelvin Mercer, Trugoy the Dove (as David Jolicoeur) and Richard Morninglane
Produced by R. Thentic and De La Soul
Performed by De La Soul featuring Yummy Bingham (as Elizabeth "Yummy" Bingham)
De La Soul appears courtesy of Tommy Boy Music

User reviews179

Review

Featured review

6/10

animation good, but live action gross and boring

The Farrelly brothers are dipping into the animation pool. It's colorful and primitive animation. It's pretty good, but that's not really the problem. Surprisingly the problem is Bill Murray and live action stuff.

Frank Detomello is a slob. He eats a hard boiled egg covered with a deadly germ. And we travel inside Frank to see white blood cell policeman Osmosis Jones (Chris Rock) battle evil virus Thrax (Laurence Fishburne) with the help of Drix (David Hyde Pierce).

Bill Murray looks awful as he gets sicker and sicker. I have to ask if we're supposed to laugh at Bill? It's just gross. Not the gross out humor that the Farrellys are known for. It isn't funny at all.

The animated sections are much better. In fact I prefer they cut out the live action stuff. Chris Rock does a good voice. He has good chemistry with David Hyde Pierce's Drix. They need a few more jokes, but I like the City of Frank.