Osmosis Jones

2001
PG
1h 35m

IMDb RATING

6.3/10

39K

YOUR RATING

Home Video Trailer from Warner Home Video

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Buddy Cop Dark Comedy Hand-Drawn Animation High-Concept Comedy Police Procedural Slapstick Action Adventure Animation Comedy

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

Directors
- Bobby Farrelly
- Peter Farrelly
Writer
- Marc Hyman
Stars

See production info at IMDbPro

IMDb RATING

6.3/10

39K

YOUR RATING

Directors
- Bobby Farrelly
- Peter Farrelly
Writer
- Marc Hyman
Stars

See production info at IMDbPro

Awards
- 1 win & 8 nominations

Thrax
(voice)

Chris Rock

Osmosis Jones
(voice)

David Hyde Pierce

Drix
(voice)

Brandy Norwood

Leah
(voice)

William Shatner

Mayor Phlegmming
(voice)

Ron Howard

Tom Colonic
(voice)

Kid Rock

Kidney Rock
(voice)

Kenny Olson

Kidney Rock
(voice)

Jason Krause

Kidney Rock
(voice)

Joe C.

Kidney Rock
(voice)

Stefanie Eulinberg

Kidney Rock
(voice)

Jimmie Bones

Kidney Rock
(voice)

Uncle Kracker

Kidney Rock
(voice)

Jonathan Adams

Additional Character Voice
(voice)

Carlos Alazraqui

Additional Character Voice
(voice)

Keith Anthony

Additional Character Voice
(voice)

Eddie Barth

Additional Character Voice
(voice)

Sally Brooks

Additional Character Voice
(voice)
(as Sally Ann Brooks)

Directors
- Bobby Farrelly
- Peter Farrelly
Writer
- Marc Hyman
All cast & crew
Production, box office & more at IMDbPro

Storyline

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Did you know

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Trivia
Bill Murray's character mentions a "National Chicken Wing Festival" in Buffalo, New York. While the festival did not exist during the filming of the movie, this mention caused organizers to create an annual festival in Buffalo. The festival has been held annually on Labor Day weekend since 2002.

Goofs
Chill was sent into Frank as a flu vaccine. While he could have been a live, weakened virus had he been administered via LAIV (FluMist), this variety of the vaccine was not introduced until 2 years after the film was released. So Chill would have had to come from an injection, meaning he would be a dead virus.

Quotes
Thrax: Ebola? Let me tell you something about Ebola, baby. Ebola is a case of DANDRUFF compared to me!

Crazy credits
The title appears as bubbles, which then pop after 5 seconds.

Alternate versions
On some streaming services, the score plays on the soundtrack as opposed to a pop song during the opening scene.

Connections
Edited into Ozzy & Drix: Home with Hector (2002)

Soundtracks
Turn It Out
Written by Kelvin Mercer, Trugoy the Dove (as David Jolicoeur) and Richard Morninglane
Produced by R. Thentic and De La Soul
Performed by De La Soul featuring Yummy Bingham (as Elizabeth "Yummy" Bingham)
De La Soul appears courtesy of Tommy Boy Music

User reviews178

Review

Featured review

God help me, I really liked this film.

As an aesthete, this movie goes against everything I stand for, but I found it nonetheless very entertaining. It was like a peculiar yet satisfying mix between the Incredible Journey, Toy Story, and Lethal Weapon or Rush Hour (the whole loose-cannon, loner cop with a new partner bit).

I found the idea rather original: the human body is like a body of government, the cop is a white blood cell, the "president" was the cell whose will was that of the man (Bill Murray), the villain is a virus who hangs out in seedy areas of the body with shady characters, the bladder is a sort of train station/airport... clever stuff.

I did have issues with the "What a zit- I mean, what is it?" part, though: it landed on her lip! Wrong! I could have gone the rest of my life without seeing that. Molly Shannon is quite a sport. 7/10