- When he accepted the Golden Globe award for Best Director in 2014 for Gravity (2013), Cuaron apologized for his poor English, especially to his star Sandra Bullock, for scaring her on location during production when he said what sounded like, " I'm going to give you herpes" when he actually had said, in his thick Spanish accent, "I'm going to give you [an] ear piece.".
- He is the first Mexican-born director to win the Oscar for Best Director, achieving the feat for Gravity (2013).
- He is friends with directors Guillermo del Toro, Mira Nair, Alejandro G. Iñárritu, Terry George and Terry Gilliam.
- He's a fan of Tim Burton.
- He is one of 10 directors to win the Golden Globe, Director's Guild, BAFTA, and Oscar for the same film, and the first to have done this twice - for Gravity (2013) and then Roma (2018). The others to achieve this are Mike Nichols for The Graduate (1967), Milos Forman for One Flew Over the Cuckoo's Nest (1975), Richard Attenborough for Gandhi (1982), Oliver Stone for Platoon (1986), Steven Spielberg for Schindler's List (1993), Ang Lee for Brokeback Mountain (2005), Danny Boyle for Slumdog Millionaire (2008), Guillermo del Toro for The Shape of Water (2017), and Alejandro G. Iñárritu for The Revenant (2015).
- He has never read the novel 'The Children of Men' by P.D. James in which is film Children of Men (2006) is based on.
- He had never read any of the Harry Potter books when he was offered to direct the third film.
- Alfonso Cuarón becomes the first person in Oscar history to be nominated for the Academy Awards for both Best Director and Best Cinematography in the same year and for the same film. He was nominated in both categories for his work on Roma (2018). He received additional nominations for Best Original Screenplay and Best Picture for the film as well.
- After divorcing from his ex-wife, Annalisa Bugliani, he moved from New York where they lived with their children, and now lives in London.
- Member of the jury at the Cannes Film Festival in 2008.
- He was attached to direct Life of Pi (2012), but due to the production of Children of Men (2006), he had to step aside the director's chair. Jean-Pierre Jeunet and then finally Ang Lee replaced him.
- Was attached to direct Speed Racer (2008) with Johnny Depp in lead, but the job went to Wachowski sisters.
- In 2007, he was one of 10 Mexican Oscar-nominees. The others were Alejandro G. Iñárritu, Guillermo Arriaga, Guillermo del Toro, Adriana Barraza, Guillermo Navarro, Emmanuel Lubezki, Eugenio Caballero, Pilar Revuelta and Fernando Cámara.
- Cuarón is one of the few directors who has directed films that have received all five modern MPAA ratings: G (A Little Princess), PG (Harry Potter and the Prisoner of Azkaban), PG-13 (Gravity), R (Great Expectations, Children of Men, Paris, je t'aime and Roma) and NC-17 (Y Tu Mamá También). In the last case, the film surrendered said rating and was released unrated in the United States.
- Was considered to direct The Hunger Games: Catching Fire (2013).
- He was set to write/direct the film Hart's War (2002) but when production was about to begin he decided to do Y tu mamá también (2001) instead.
- He became attached to direct the film Runaway Jury (2003) but after a few months he left the project.
- To date, only one of four people to have won the Best Director Oscar more than once without any of those films having won the Oscar for Best Picture. His two wins are for Gravity (2013) and Roma (2018). The other three individuals are Frank Borzage for directing 7th Heaven (1927) and Bad Girl (1931), George Stevens for directing A Place in the Sun (1951) and Giant (1956), and Ang Lee for directing Brokeback Mountain (2005) and Life of Pi (2012).
- Was considered to direct Pirates of the Caribbean: Dead Men Tell No Tales (2017).
- One of Time Magazine's 100 Most Influential People in the World. [April 2014].
- He turned down the chance to direct Addicted to Love (1997) to work instead on A Little Princess (1995).
- He is friends with singer Ian Brown and offered to direct one of his future videos.
- Won the 2019 Academy Award in the Best Director category for his work on Roma (2018).
- He was the mentor of actor/director Dean Paraskevopoulos.
- Alfonso Cuarón won the 2019 Academy Award in the Best Cinematography category for his work on Roma (2018).
- He was the original director of the film The Perez Family (1995), but pulled out before production started.
- Brother of Carlos Cuarón.
- Has been nominated in six different categories at the Academy Awards: Best Director, Best Film Editing, Best Cinematography, Best Picture, Best Adapted Screenplay and Best Original Screenplay, winning Oscars in the first three categories.
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