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ZA92234B - Novel steroid esters - Google Patents

Novel steroid esters

Info

Publication number
ZA92234B
ZA92234B ZA92234A ZA92234A ZA92234B ZA 92234 B ZA92234 B ZA 92234B ZA 92234 A ZA92234 A ZA 92234A ZA 92234 A ZA92234 A ZA 92234A ZA 92234 B ZA92234 B ZA 92234B
Authority
ZA
South Africa
Prior art keywords
novel steroid
steroid esters
esters
novel
steroid
Prior art date
Application number
ZA92234A
Other languages
English (en)
Inventor
Bengt Ingemar Axelsson
Ralph Lennart Brattsand
Leif Arne Kaellstroem
Arne Bror Thalen
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA92234B publication Critical patent/ZA92234B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA92234A 1991-02-04 1992-01-13 Novel steroid esters ZA92234B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters

Publications (1)

Publication Number Publication Date
ZA92234B true ZA92234B (en) 1992-10-28

Family

ID=20381807

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA92234A ZA92234B (en) 1991-02-04 1992-01-13 Novel steroid esters

Country Status (38)

Country Link
US (1) US5614514A (es)
EP (1) EP0572451B1 (es)
JP (1) JP2947933B2 (es)
KR (1) KR100205835B1 (es)
CN (3) CN1039329C (es)
AP (1) AP365A (es)
AT (1) ATE164589T1 (es)
BG (1) BG61816B1 (es)
CA (1) CA2100453A1 (es)
CZ (1) CZ282057B6 (es)
DE (1) DE69224982T2 (es)
DK (1) DK0572451T3 (es)
DZ (1) DZ1554A1 (es)
EE (1) EE03110B1 (es)
ES (1) ES2114931T3 (es)
FI (1) FI933451A (es)
HK (1) HK1004335A1 (es)
HU (1) HU221168B1 (es)
IE (1) IE920167A1 (es)
IL (1) IL100542A (es)
IS (1) IS1653B (es)
MA (1) MA22407A1 (es)
MX (1) MX9200374A (es)
MY (1) MY111502A (es)
NO (1) NO304074B1 (es)
NZ (1) NZ241211A (es)
PL (1) PL170383B1 (es)
PT (1) PT100087B (es)
RO (1) RO111272B1 (es)
RU (1) RU2112775C1 (es)
SE (1) SE9100342D0 (es)
SK (1) SK281802B6 (es)
TN (1) TNSN92008A1 (es)
TW (1) TW287166B (es)
UA (1) UA43825C2 (es)
WO (1) WO1992013873A1 (es)
YU (1) YU48893B (es)
ZA (1) ZA92234B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
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SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
BR9307746A (pt) * 1993-01-08 1995-11-14 Astra Ab Derivados de esteróides especificos para otratamento de cólon e ileo
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
US6372712B1 (en) 1998-05-22 2002-04-16 The Board Of Trustees Of The Leland Stanford Jr. University Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand
IL146132A0 (en) 1999-05-27 2002-07-25 Euro Celtique Sa Preparations for the application of anti-infective and/or anti-inflammatory agents to external or internal parts of the human or animal body in functional and cosmetic tissue remodelling and repair treatments
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
US20050009798A1 (en) 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
AU2003217535A1 (en) * 2002-02-20 2003-09-09 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids
CA2489402A1 (en) 2002-07-08 2004-01-15 Pliva-Istrazivacki Institut D.O.O. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
JP4530851B2 (ja) 2002-07-08 2010-08-25 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ ステロイド/非ステロイド抗炎症活性分子、抗新生物活性分子および抗ウイルス活性分子用担体としての新規な化合物、組成物
US20040157810A1 (en) * 2002-08-23 2004-08-12 Teicher Martin H. Corticosteroid conjugates and uses thereof
WO2004033478A2 (en) * 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
WO2005016352A1 (en) * 2003-08-05 2005-02-24 Sepracor Inc. AMINO ACID AND PEPTIDE-MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH ß2 ADRENERGIC AGONISTS
MX2007005073A (es) 2004-10-27 2007-06-25 Glaxosmithkline Zagreb Conjugados con actividad antiinflamtoria.
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US8737506B1 (en) 2010-12-29 2014-05-27 Sprint Communications Company L.P. Determination of transmit diversity transmission delays
US8437713B1 (en) 2011-02-16 2013-05-07 Sprint Communications Company L.P. Wireless transmit diversity control by location of a wireless communication device
US8565686B2 (en) 2011-06-30 2013-10-22 Sprint Communications Company L.P. Power status multipath search window sizing for wireless communications
TWI620578B (zh) 2012-02-10 2018-04-11 台灣微脂體股份有限公司 用以減少眼用類固醇的倂發症之藥學組成物
JP5965187B2 (ja) * 2012-03-30 2016-08-03 小林製薬株式会社 油性軟膏剤
CN109985048B (zh) * 2017-12-29 2021-06-29 广州市赛普特医药科技股份有限公司 2β,3α,5α-三羟基雄甾-6-酮用于炎症反应的治疗

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3197469A (en) * 1958-08-06 1965-07-27 Pharmaceutical Res Products In 16, 17-acetals and ketals of 6-halo-16, 17-dihydroxy steroids of the pregnane seriesand intermediates therefor
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378109B (es) * 1972-05-19 1975-08-18 Bofors Ab
US3796701A (en) * 1973-02-26 1974-03-12 Squibb & Sons Inc 5alpha,9-oxazino steroids and 9-carboxamido steroids
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4304727A (en) * 1980-12-05 1981-12-08 The Upjohn Company 9α-Debromination
JPS58176485A (ja) * 1982-04-08 1983-10-15 Nippon Denso Co Ltd 可変容量圧縮機
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6067496A (ja) * 1983-09-26 1985-04-17 Ota Seiyaku Kk フルオシノロン16,17−アセトニド21−ブチレ−トおよびその製造法
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters

Also Published As

Publication number Publication date
EE03110B1 (et) 1998-08-17
TW287166B (es) 1996-10-01
CN1039329C (zh) 1998-07-29
MX9200374A (es) 1992-08-01
CZ149593A3 (en) 1994-03-16
AP9200354A0 (en) 1992-01-31
CZ282057B6 (cs) 1997-05-14
WO1992013873A1 (en) 1992-08-20
IS3809A (is) 1992-08-05
DE69224982T2 (de) 1998-07-30
CN1064078A (zh) 1992-09-02
AU661472B2 (en) 1995-07-27
UA43825C2 (uk) 2002-01-15
YU6492A (sh) 1994-12-28
JPH06505233A (ja) 1994-06-16
DE69224982D1 (de) 1998-05-07
FI933451A0 (fi) 1993-08-03
ES2114931T3 (es) 1998-06-16
PT100087A (pt) 1993-05-31
AP365A (en) 1994-10-21
YU48893B (sh) 2002-10-18
CN1076606C (zh) 2001-12-26
EP0572451B1 (en) 1998-04-01
SK79793A3 (en) 1994-03-09
NO932762D0 (no) 1993-08-02
DK0572451T3 (da) 1998-10-19
BG61816B1 (bg) 1998-06-30
RO111272B1 (ro) 1996-08-30
PL170383B1 (pl) 1996-12-31
MY111502A (en) 2000-07-31
US5614514A (en) 1997-03-25
MA22407A1 (fr) 1992-10-01
CN1158726A (zh) 1997-09-10
HU221168B1 (en) 2002-08-28
IL100542A0 (en) 1992-09-06
HUT64972A (en) 1994-03-28
RU2112775C1 (ru) 1998-06-10
HK1004335A1 (en) 1998-11-20
SK281802B6 (sk) 2001-08-06
JP2947933B2 (ja) 1999-09-13
BG98011A (bg) 1994-04-29
NO304074B1 (no) 1998-10-19
FI933451A (fi) 1993-08-03
PT100087B (pt) 1999-09-30
DZ1554A1 (fr) 2002-02-17
ATE164589T1 (de) 1998-04-15
IE920167A1 (en) 1992-08-12
IL100542A (en) 1997-02-18
TNSN92008A1 (fr) 1993-06-08
HU9302243D0 (en) 1993-10-28
CN1155418A (zh) 1997-07-30
NO932762L (no) 1993-08-02
CN1076607C (zh) 2001-12-26
EP0572451A1 (en) 1993-12-08
NZ241211A (en) 1993-08-26
CA2100453A1 (en) 1992-08-05
AU1235892A (en) 1992-09-07
IS1653B (is) 1997-06-20
SE9100342D0 (sv) 1991-02-04
KR100205835B1 (ko) 1999-07-01

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