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ATE164589T1 - Neue steroid-ester - Google Patents

Neue steroid-ester

Info

Publication number
ATE164589T1
ATE164589T1 AT92904423T AT92904423T ATE164589T1 AT E164589 T1 ATE164589 T1 AT E164589T1 AT 92904423 T AT92904423 T AT 92904423T AT 92904423 T AT92904423 T AT 92904423T AT E164589 T1 ATE164589 T1 AT E164589T1
Authority
AT
Austria
Prior art keywords
steroid esters
new steroid
esters
new
steroid
Prior art date
Application number
AT92904423T
Other languages
English (en)
Inventor
Bengt Axelsson
Ralph Brattsand
Leif Kaellstroem
N Arne Thal
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of ATE164589T1 publication Critical patent/ATE164589T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT92904423T 1991-02-04 1992-01-29 Neue steroid-ester ATE164589T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters

Publications (1)

Publication Number Publication Date
ATE164589T1 true ATE164589T1 (de) 1998-04-15

Family

ID=20381807

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92904423T ATE164589T1 (de) 1991-02-04 1992-01-29 Neue steroid-ester

Country Status (38)

Country Link
US (1) US5614514A (de)
EP (1) EP0572451B1 (de)
JP (1) JP2947933B2 (de)
KR (1) KR100205835B1 (de)
CN (3) CN1039329C (de)
AP (1) AP365A (de)
AT (1) ATE164589T1 (de)
BG (1) BG61816B1 (de)
CA (1) CA2100453A1 (de)
CZ (1) CZ282057B6 (de)
DE (1) DE69224982T2 (de)
DK (1) DK0572451T3 (de)
DZ (1) DZ1554A1 (de)
EE (1) EE03110B1 (de)
ES (1) ES2114931T3 (de)
FI (1) FI933451A (de)
HK (1) HK1004335A1 (de)
HU (1) HU221168B1 (de)
IE (1) IE920167A1 (de)
IL (1) IL100542A (de)
IS (1) IS1653B (de)
MA (1) MA22407A1 (de)
MX (1) MX9200374A (de)
MY (1) MY111502A (de)
NO (1) NO304074B1 (de)
NZ (1) NZ241211A (de)
PL (1) PL170383B1 (de)
PT (1) PT100087B (de)
RO (1) RO111272B1 (de)
RU (1) RU2112775C1 (de)
SE (1) SE9100342D0 (de)
SK (1) SK281802B6 (de)
TN (1) TNSN92008A1 (de)
TW (1) TW287166B (de)
UA (1) UA43825C2 (de)
WO (1) WO1992013873A1 (de)
YU (1) YU48893B (de)
ZA (1) ZA92234B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
RU95115547A (ru) * 1993-01-08 1997-06-10 Астра Актиеболаг (SE) Стероидные соединения, способы их получения и фармацевтический препарат
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
EP1180017B8 (de) 1999-05-27 2010-05-19 Euro-Celtique S.A. Formulierungen mit povidon-iod zur behandlung von wunden
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
US20050009798A1 (en) 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
AU2003217535A1 (en) 2002-02-20 2003-09-09 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids
NZ537717A (en) 2002-07-08 2006-04-28 Pliva Istrazivacki Inst D New compounds, compositions and methods for treatment of inflammatory diseases and conditions
US7157433B2 (en) 2002-07-08 2007-01-02 Glaxosmithkline Istrazivacki Centar Zagreb Compounds, compositions as carriers for steroid/nonsteroid anti-inflammatory; antienoplastic and antiviral active molecules
AU2003265576A1 (en) * 2002-08-23 2004-03-11 The Mclean Hospital Corporation Corticosteroid conjugates and uses thereof
US20040235811A1 (en) * 2002-10-08 2004-11-25 Sepracor Inc. Fatty acid modified forms of glucocorticoids
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
AU2003257154A1 (en) * 2003-08-05 2005-03-07 Sepracor Inc. AMINO ACID AND PEPTIDE-MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH ss2 ADRENERGIC AGONISTS
ES2337915T3 (es) 2004-10-27 2010-04-30 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Conjugados con adtividad antiinflamatoria.
CA2608144C (en) 2005-04-28 2012-11-13 Proteus Biomedical, Inc. Pharma-informatics system
EP1945240B1 (de) 2005-09-16 2016-12-28 Raptor Pharmaceutical Inc Zusammensetzungen mit rezeptor-assoziierten protein (rap) varianten, die für cr-haltige proteine spezifisch sind und ihre verwendungen
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
AU2010245823B2 (en) 2009-05-06 2016-11-24 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US8737506B1 (en) 2010-12-29 2014-05-27 Sprint Communications Company L.P. Determination of transmit diversity transmission delays
US8437713B1 (en) 2011-02-16 2013-05-07 Sprint Communications Company L.P. Wireless transmit diversity control by location of a wireless communication device
US8565686B2 (en) 2011-06-30 2013-10-22 Sprint Communications Company L.P. Power status multipath search window sizing for wireless communications
TR201808592T4 (tr) 2012-02-10 2018-07-23 Taiwan Liposome Co Ltd Oküler steroi̇d kompli̇kasyonlarinin azaltimina yöneli̇k farmasöti̇k bi̇leşi̇mler.
JP5965187B2 (ja) * 2012-03-30 2016-08-03 小林製薬株式会社 油性軟膏剤
CN109985048B (zh) * 2017-12-29 2021-06-29 广州市赛普特医药科技股份有限公司 2β,3α,5α-三羟基雄甾-6-酮用于炎症反应的治疗

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3197469A (en) * 1958-08-06 1965-07-27 Pharmaceutical Res Products In 16, 17-acetals and ketals of 6-halo-16, 17-dihydroxy steroids of the pregnane seriesand intermediates therefor
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378109B (de) * 1972-05-19 1975-08-18 Bofors Ab
US3796701A (en) * 1973-02-26 1974-03-12 Squibb & Sons Inc 5alpha,9-oxazino steroids and 9-carboxamido steroids
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4304727A (en) * 1980-12-05 1981-12-08 The Upjohn Company 9α-Debromination
JPS58176485A (ja) * 1982-04-08 1983-10-15 Nippon Denso Co Ltd 可変容量圧縮機
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6067496A (ja) * 1983-09-26 1985-04-17 Ota Seiyaku Kk フルオシノロン16,17−アセトニド21−ブチレ−トおよびその製造法
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters

Also Published As

Publication number Publication date
RO111272B1 (ro) 1996-08-30
CN1076606C (zh) 2001-12-26
RU2112775C1 (ru) 1998-06-10
EE03110B1 (et) 1998-08-17
IS3809A (is) 1992-08-05
AP365A (en) 1994-10-21
SK79793A3 (en) 1994-03-09
WO1992013873A1 (en) 1992-08-20
YU6492A (sh) 1994-12-28
NO304074B1 (no) 1998-10-19
AP9200354A0 (en) 1992-01-31
ZA92234B (en) 1992-10-28
CN1064078A (zh) 1992-09-02
PT100087A (pt) 1993-05-31
BG61816B1 (bg) 1998-06-30
AU661472B2 (en) 1995-07-27
US5614514A (en) 1997-03-25
AU1235892A (en) 1992-09-07
CN1158726A (zh) 1997-09-10
SK281802B6 (sk) 2001-08-06
IS1653B (is) 1997-06-20
CN1155418A (zh) 1997-07-30
BG98011A (bg) 1994-04-29
NZ241211A (en) 1993-08-26
MA22407A1 (fr) 1992-10-01
JP2947933B2 (ja) 1999-09-13
UA43825C2 (uk) 2002-01-15
CZ149593A3 (en) 1994-03-16
ES2114931T3 (es) 1998-06-16
CN1076607C (zh) 2001-12-26
HK1004335A1 (en) 1998-11-20
CZ282057B6 (cs) 1997-05-14
YU48893B (sh) 2002-10-18
IL100542A (en) 1997-02-18
KR100205835B1 (ko) 1999-07-01
IL100542A0 (en) 1992-09-06
HU9302243D0 (en) 1993-10-28
FI933451A0 (fi) 1993-08-03
DE69224982D1 (de) 1998-05-07
PT100087B (pt) 1999-09-30
HUT64972A (en) 1994-03-28
TW287166B (de) 1996-10-01
TNSN92008A1 (fr) 1993-06-08
IE920167A1 (en) 1992-08-12
EP0572451B1 (de) 1998-04-01
JPH06505233A (ja) 1994-06-16
CN1039329C (zh) 1998-07-29
FI933451A (fi) 1993-08-03
HU221168B1 (en) 2002-08-28
DK0572451T3 (da) 1998-10-19
DZ1554A1 (fr) 2002-02-17
CA2100453A1 (en) 1992-08-05
EP0572451A1 (de) 1993-12-08
PL170383B1 (pl) 1996-12-31
NO932762L (no) 1993-08-02
SE9100342D0 (sv) 1991-02-04
DE69224982T2 (de) 1998-07-30
NO932762D0 (no) 1993-08-02
MY111502A (en) 2000-07-31
MX9200374A (es) 1992-08-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee