ZA884513B - Drug emulsion - Google Patents

Drug emulsion

Info

Publication number: ZA884513B
Authority: ZA; South Africa
Prior art keywords: drug; solvent; emulsion; mixing; oil
Prior art date: 1987-06-23

Application number

ZA884513A

Other languages

English (en)

Inventor

Stewart Stanley Davis

Stanley Davis Stewart

Clive Washington

Washington Clive

Original Assignee

Univ Nottingham

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-23

Filing date

1988-06-23

Publication date

1989-03-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10619376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA884513(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1988-06-23 Application filed by Univ Nottingham filed Critical Univ Nottingham

1989-03-29 Publication of ZA884513B publication Critical patent/ZA884513B/xx

Links

229940079593 drug Drugs 0.000 title abstract 7
239000003814 drug Substances 0.000 title abstract 7
239000000839 emulsion Substances 0.000 title abstract 3
239000006184 cosolvent Substances 0.000 abstract 3
239000004094 surface-active agent Substances 0.000 abstract 2
APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 abstract 1
APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 abstract 1
229960003942 amphotericin b Drugs 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000007764 o/w emulsion Substances 0.000 abstract 1
150000004291 polyenes Chemical class 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Biophysics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

ZA884513A 1987-06-23 1988-06-23 Drug emulsion ZA884513B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB878714652A GB8714652D0 (en)	1987-06-23	1987-06-23	Drug emulsion

Publications (1)

Publication Number	Publication Date
ZA884513B true ZA884513B (en)	1989-03-29

Family

ID=10619376

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA884513A ZA884513B (en)	1987-06-23	1988-06-23	Drug emulsion

Country Status (7)

Country	Link
EP (1)	EP0296845B1 (xx)
AT (1)	ATE79262T1 (xx)
AU (1)	AU1957388A (xx)
DE (1)	DE3873641T2 (xx)
GB (1)	GB8714652D0 (xx)
WO (1)	WO1988010116A1 (xx)
ZA (1)	ZA884513B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5616334A (en) *	1987-03-05	1997-04-01	The Liposome Company, Inc.	Low toxicity drug-lipid systems
US6406713B1 (en)	1987-03-05	2002-06-18	The Liposome Company, Inc.	Methods of preparing low-toxicity drug-lipid complexes
CA2013755C (en) †	1989-04-05	1993-11-30	Simon Benita	Medicinal emulsions
GB8919172D0 (en) *	1989-08-23	1989-10-04	Univ Nottingham	Useful composition
KR0151704B1 (ko) *	1989-11-27	1998-10-15	아만 히데아키	지방 유제
US5534502A (en) *	1990-11-06	1996-07-09	Nippon Shinyaku Co. Ltd.	Process for producing fat emulsion
EP0556392A4 (en) *	1990-11-06	1994-03-17	Nippon Shinyaku Co Ltd	PROCESS FOR PRODUCING A FATTY EMULSION.
US6447806B1 (en)	1999-02-25	2002-09-10	Novartis Ag	Pharmaceutical compositions comprised of stabilized peptide particles
IN188843B (xx) *	2000-06-22	2002-11-09	Vinod Daftary Gautam Dr
DE10036871A1 (de) *	2000-07-28	2002-02-14	Pharmasol Gmbh	Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
US20080124387A1 (en) *	2006-11-27	2008-05-29	Kapac, Llc	Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57501845A (xx) *	1980-11-27	1982-10-14
EP0125313A1 (en) *	1982-11-08	1984-11-21	Wm. Wrigley Jr. Company	Anhydrous chewing gum
US4707470A (en) *	1985-05-17	1987-11-17	Smithkline Beckman Corporation	Polyene antibiotic emulsion formulation
IL78929A0 (en) *	1985-07-29	1986-09-30	Abbott Lab	Microemulsion compositions for parenteral administration
US4784845A (en) *	1985-09-16	1988-11-15	American Cyanamid Company	Emulsion compostions for the parenteral administration of sparingly water soluble ionizable hydrophobic drugs

1987
- 1987-06-23 GB GB878714652A patent/GB8714652D0/en active Pending
1988
- 1988-06-22 DE DE8888305718T patent/DE3873641T2/de not_active Expired - Fee Related
- 1988-06-22 WO PCT/GB1988/000486 patent/WO1988010116A1/en unknown
- 1988-06-22 EP EP88305718A patent/EP0296845B1/en not_active Expired - Lifetime
- 1988-06-22 AT AT88305718T patent/ATE79262T1/de not_active IP Right Cessation
- 1988-06-22 AU AU19573/88A patent/AU1957388A/en not_active Abandoned
- 1988-06-23 ZA ZA884513A patent/ZA884513B/xx unknown

Also Published As

Publication number	Publication date
AU1957388A (en)	1989-01-19
DE3873641D1 (de)	1992-09-17
DE3873641T2 (de)	1993-02-11
WO1988010116A1 (en)	1988-12-29
GB8714652D0 (en)	1987-07-29
EP0296845A1 (en)	1988-12-28
ATE79262T1 (de)	1992-08-15
EP0296845B1 (en)	1992-08-12

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