ZA200802225B - Interleukin-1 conjugates and uses thereof - Google Patents
Interleukin-1 conjugates and uses thereofInfo
- Publication number
- ZA200802225B ZA200802225B ZA200802225A ZA200802225A ZA200802225B ZA 200802225 B ZA200802225 B ZA 200802225B ZA 200802225 A ZA200802225 A ZA 200802225A ZA 200802225 A ZA200802225 A ZA 200802225A ZA 200802225 B ZA200802225 B ZA 200802225B
- Authority
- ZA
- South Africa
- Prior art keywords
- conjugates
- interleukin
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/06—Antipsoriatics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
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- A61K2039/5258—Virus-like particles
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
-
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18123—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72110605P | 2005-09-28 | 2005-09-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200802225B true ZA200802225B (en) | 2009-10-28 |
Family
ID=37497973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200802225A ZA200802225B (en) | 2005-09-28 | 2006-09-28 | Interleukin-1 conjugates and uses thereof |
Country Status (13)
Country | Link |
---|---|
US (3) | US20110027220A1 (xx) |
EP (2) | EP2431468A1 (xx) |
JP (1) | JP5312028B2 (xx) |
KR (1) | KR20080047564A (xx) |
CN (2) | CN103230590A (xx) |
AU (1) | AU2006298767B2 (xx) |
BR (1) | BRPI0616446A2 (xx) |
CA (1) | CA2623287A1 (xx) |
IL (1) | IL189245A0 (xx) |
NZ (1) | NZ566971A (xx) |
RU (1) | RU2441067C2 (xx) |
WO (1) | WO2007039552A1 (xx) |
ZA (1) | ZA200802225B (xx) |
Families Citing this family (31)
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ES2335979T3 (es) | 2001-09-14 | 2010-04-07 | Cytos Biotechnology Ag | Empaquetamiento de cpg inmunoestimuladores en particulas similares a virus: metodo de preparacion y su uso. |
US8187817B2 (en) | 2005-08-02 | 2012-05-29 | Xbiotech, Inc. | Diagnosis, treatment, and prevention of vascular disorders using IL-1 autoantibodies |
US20110008282A1 (en) * | 2006-05-15 | 2011-01-13 | Xbiotech, Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
AU2007251239B2 (en) * | 2006-05-15 | 2013-08-22 | Xbiotech Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
KR101552227B1 (ko) | 2006-06-12 | 2015-09-10 | 사이토스 바이오테크놀로지 아게 | 올리고뉴클레오티드를 rna 박테리오파지의 바이러스-유사 입자로 패키징하는 방법 |
WO2008071774A1 (en) * | 2006-12-14 | 2008-06-19 | Cytos Biotechnology Ag | Purification process for coat protein of rna bacteriophages |
EP2195016A1 (en) * | 2007-09-25 | 2010-06-16 | Intervet International B.V. | Vaccine for the treatment of osteoarthritis |
CN101959526A (zh) * | 2008-03-05 | 2011-01-26 | 赛托斯生物技术公司 | 白介素-1偶联物在糖尿病治疗中的用途 |
MX2010012963A (es) | 2008-05-30 | 2011-04-05 | Xbiotech Inc | Anticuerpos de interleucina-1 alfa y metodos de uso. |
US8242074B2 (en) | 2008-09-12 | 2012-08-14 | Xbiotech, Inc. | Modulation of the amount or function of pathogenic CD14+CD16+ monocytes |
PL222496B1 (pl) * | 2009-04-10 | 2016-08-31 | Inst Biochemii I Biofizyki Pan | Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania oraz kompozycja farmaceutyczna zawierająca wektorową cząsteczkę wirusopodobną |
US8993715B2 (en) * | 2009-07-06 | 2015-03-31 | Canon Kabushiki Kaisha | Labeled protein and method for obtaining the same |
CA2773426A1 (en) * | 2009-09-10 | 2011-03-17 | Cytos Biotechnology Ag | Use of interleukin-1 beta mutein conjugates in the treatment of diabetes |
CN102946904A (zh) | 2010-06-18 | 2013-02-27 | 埃克斯生物科技公司 | 关节炎治疗 |
KR101910760B1 (ko) | 2010-08-23 | 2018-10-22 | 엑스바이오테크, 인크. | 종양성 질병들에 대한 치료 |
US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
CA2849710C (en) | 2011-09-23 | 2020-04-28 | Xbiotech Inc. | Cachexia treatment |
WO2013124474A2 (en) | 2012-02-23 | 2013-08-29 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
GB201300684D0 (en) | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
US11168306B2 (en) | 2014-02-25 | 2021-11-09 | The Regents Of The University Of California | Phage wrapping |
CA3010975A1 (en) | 2015-01-15 | 2016-07-21 | University Of Copenhagen | Virus-like particle with efficient epitope display |
MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
CN108474002B (zh) * | 2015-10-22 | 2023-05-23 | 朱诺治疗学有限公司 | 用于转导的方法、反应剂盒、反应剂和设备 |
ES2854726T3 (es) | 2015-10-30 | 2021-09-22 | The Univ Of Copenhagen | Partícula similar a virus con presentación eficiente de epítopos |
MX2019009798A (es) | 2017-02-16 | 2020-01-30 | Xbiotech Inc | Tratamiento de la hidradenitis supurativa. |
WO2018197949A1 (en) | 2017-04-27 | 2018-11-01 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
EP3775218A1 (en) | 2018-04-09 | 2021-02-17 | Checkmate Pharmaceuticals | Packaging oligonucleotides into virus-like particles |
EP3845556A1 (fr) * | 2019-12-31 | 2021-07-07 | Peptinov SAS | Conjugue immunogene destine a induire une reponse immunitaire dirigee contre l interleukine-6 |
US20240358826A1 (en) * | 2021-07-08 | 2024-10-31 | Orionis Biosciences, Inc. | Interleukin-1 alpha chimeric protein |
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US5374426A (en) | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
AU5171890A (en) * | 1989-02-27 | 1990-09-26 | Massachusetts Institute Of Technology | Il-1 biological activity inhibitors |
AU9052091A (en) | 1990-12-20 | 1992-07-22 | Smithkline Beecham Biologicals (Sa) | Vaccines based on hepatitis b surface antigen |
GB9101550D0 (en) | 1991-01-24 | 1991-03-06 | Mastico Robert A | Antigen-presenting chimaeric protein |
FR2677654B1 (fr) | 1991-06-17 | 1995-11-17 | Pasteur Merieux Serums Vacc | Composes a effet immunogene anti-cytokine, a effet immunogene anticytostatique ou a effet vaccinal anti-infection a hiv. |
GB9114003D0 (en) | 1991-06-28 | 1991-08-14 | Mastico Robert A | Chimaeric protein |
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DE10004232A1 (de) | 2000-02-01 | 2001-08-02 | Megamat Gmbh Buero Und Lagerte | Antriebseinrichtung für eine Lagervorrichtung |
WO2001057219A2 (en) * | 2000-02-02 | 2001-08-09 | Schering Corporation | Mammalian interleukin-1-delta and -epsilon. their use in therapeutic and diagnostic methods |
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ES2335979T3 (es) | 2001-09-14 | 2010-04-07 | Cytos Biotechnology Ag | Empaquetamiento de cpg inmunoestimuladores en particulas similares a virus: metodo de preparacion y su uso. |
NZ531534A (en) * | 2001-10-05 | 2005-10-28 | Cytos Biotechnology Ag | Angiotensin peptides conjugated with a carrier comprising a virus-like particle |
RU2322258C2 (ru) * | 2001-11-07 | 2008-04-20 | Цитос Байотекнолоджи Аг | Антигенные матрицы для лечения заболевания костей |
RU2319503C2 (ru) * | 2001-11-07 | 2008-03-20 | Цитос Байотекнолоджи Аг | Композиция для иммунизации (варианты), способ ее получения и применение для лечения аллергических эозинофильных заболеваний |
CA2466492A1 (en) * | 2001-11-07 | 2003-05-15 | Cytos Biotechnology Ag | Antigen arrays presenting il-5, il-13 or eotaxin for treatment of allergic eosinophilic diseases |
FR2838444B1 (fr) | 2002-04-10 | 2016-01-01 | Neovacs | Nouveaux peptides et leur application en therapeutique |
CN1668637B (zh) * | 2002-07-17 | 2010-05-26 | 希托斯生物技术股份公司 | 使用衍生自ap205外壳蛋白的病毒样颗粒的分子抗原阵列 |
WO2004009116A2 (en) * | 2002-07-18 | 2004-01-29 | Cytos Biotechnology Ag | Hapten-carrier conjugates comprising virus like particles and uses thereof |
BR0311800A (pt) * | 2002-07-19 | 2005-03-22 | Cytos Biotechnology Ag | Conjugados ghrelina-veìculo |
AU2005205181A1 (en) * | 2004-01-20 | 2005-07-28 | Cytos Biotechnology Ag | Particle-induced ghrelin immune response |
CA2580208A1 (en) | 2004-09-21 | 2006-03-30 | Cytos Biotechnology Ag | Virus-like particles comprising a fusion protein of the coat protein of ap205 and an antigenic polypeptide |
EP1812051A2 (en) | 2004-10-05 | 2007-08-01 | Cytos Biotechnology AG | Vlp-antigen conjugates and their uses as vaccines |
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2006
- 2006-09-28 CN CN2013101441929A patent/CN103230590A/zh active Pending
- 2006-09-28 EP EP11175319A patent/EP2431468A1/en not_active Withdrawn
- 2006-09-28 US US11/992,731 patent/US20110027220A1/en not_active Abandoned
- 2006-09-28 ZA ZA200802225A patent/ZA200802225B/xx unknown
- 2006-09-28 JP JP2008532788A patent/JP5312028B2/ja not_active Expired - Fee Related
- 2006-09-28 AU AU2006298767A patent/AU2006298767B2/en not_active Ceased
- 2006-09-28 WO PCT/EP2006/066866 patent/WO2007039552A1/en active Application Filing
- 2006-09-28 CN CN2006800343698A patent/CN101267834B/zh not_active Expired - Fee Related
- 2006-09-28 CA CA002623287A patent/CA2623287A1/en not_active Abandoned
- 2006-09-28 NZ NZ566971A patent/NZ566971A/en not_active IP Right Cessation
- 2006-09-28 BR BRPI0616446-3A patent/BRPI0616446A2/pt not_active IP Right Cessation
- 2006-09-28 EP EP06793894A patent/EP1931383A1/en not_active Withdrawn
- 2006-09-28 KR KR1020087006840A patent/KR20080047564A/ko not_active Application Discontinuation
- 2006-09-28 RU RU2008116323/10A patent/RU2441067C2/ru not_active IP Right Cessation
-
2007
- 2007-03-29 US US12/443,344 patent/US8449874B2/en not_active Expired - Fee Related
-
2008
- 2008-02-04 IL IL189245A patent/IL189245A0/en unknown
-
2012
- 2012-08-01 US US13/564,576 patent/US20130230484A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101267834B (zh) | 2013-06-05 |
US8449874B2 (en) | 2013-05-28 |
CA2623287A1 (en) | 2007-04-12 |
AU2006298767A1 (en) | 2007-04-12 |
JP2009510025A (ja) | 2009-03-12 |
EP2431468A1 (en) | 2012-03-21 |
RU2008116323A (ru) | 2009-11-10 |
CN103230590A (zh) | 2013-08-07 |
CN101267834A (zh) | 2008-09-17 |
IL189245A0 (en) | 2008-08-07 |
BRPI0616446A2 (pt) | 2011-06-21 |
EP1931383A1 (en) | 2008-06-18 |
RU2441067C2 (ru) | 2012-01-27 |
US20130230484A1 (en) | 2013-09-05 |
WO2007039552A1 (en) | 2007-04-12 |
KR20080047564A (ko) | 2008-05-29 |
US20110027220A1 (en) | 2011-02-03 |
US20110091411A1 (en) | 2011-04-21 |
NZ566971A (en) | 2011-06-30 |
JP5312028B2 (ja) | 2013-10-09 |
AU2006298767B2 (en) | 2013-01-10 |
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