ZA200805658B - Prodrugs of ER-beta-selective substances method for production thereof and pharmaceutical compositions comprising the same - Google Patents

Prodrugs of ER-beta-selective substances method for production thereof and pharmaceutical compositions comprising the same

Info

Publication number: ZA200805658B
Authority: ZA; South Africa
Prior art keywords: prodrugs; beta; production; same; pharmaceutical compositions
Prior art date: 2005-11-29

Application number

ZA200805658A

Other languages

English (en)

Inventor

Olaf Peters

Gudrun Reddersen

Ralf Wyrwa

Alexander Hillisch

Walter Elger

Katja Prelle

Peter Droescher

Original Assignee

Bayer Schering Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-29

Filing date

2008-06-27

Publication date

2010-01-27

2008-06-27 Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag

2010-01-27 Publication of ZA200805658B publication Critical patent/ZA200805658B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200805658A 2005-11-29 2008-06-27 Prodrugs of ER-beta-selective substances method for production thereof and pharmaceutical compositions comprising the same ZA200805658B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE102005057225A DE102005057225A1 (de)	2005-11-29	2005-11-29	Prodrugs ERß-selektiver Substanzen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number	Publication Date
ZA200805658B true ZA200805658B (en)	2010-01-27

Family

ID=37909446

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200805658A ZA200805658B (en)	2005-11-29	2008-06-27	Prodrugs of ER-beta-selective substances method for production thereof and pharmaceutical compositions comprising the same

Country Status (14)

Country	Link
EP (1)	EP1957514A1 (fr)
JP (1)	JP2009517426A (fr)
KR (1)	KR20080072087A (fr)
CN (1)	CN101316856A (fr)
AU (1)	AU2006319382A1 (fr)
BR (1)	BRPI0619237A2 (fr)
CA (1)	CA2630438A1 (fr)
CR (1)	CR9997A (fr)
DE (1)	DE102005057225A1 (fr)
EA (1)	EA200801272A1 (fr)
EC (1)	ECSP088482A (fr)
NO (1)	NO20082918L (fr)
WO (1)	WO2007062876A1 (fr)
ZA (1)	ZA200805658B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2016539954A (ja)	2013-12-05	2016-12-22	カロファーマエービーＫａｒｏＰｈａｒｍａＡｂ	中皮腫の処置で使用するためのエストロゲン受容体ベータアゴニスト

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL207488B1 (pl) *	2000-04-12	2010-12-31	Schering Ag	Pochodne estra-1,3,5(10)-trienu podstawione w pozycji 8ß, ich zastosowanie oraz kompozycja farmaceutyczna je zawierająca
DE10027887A1 (de) *	2000-05-31	2001-12-13	Jenapharm Gmbh	Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
DE102004025966A1 (de) *	2004-05-21	2005-12-15	Schering Ag	Estradiol-Prodrugs
US7534780B2 (en) *	2004-05-21	2009-05-19	Bayer Schering Pharma Aktiengesellschaft	Estradiol prodrugs

2005
- 2005-11-29 DE DE102005057225A patent/DE102005057225A1/de not_active Ceased
2006
- 2006-11-27 CA CA002630438A patent/CA2630438A1/fr not_active Abandoned
- 2006-11-27 WO PCT/EP2006/011728 patent/WO2007062876A1/fr active Application Filing
- 2006-11-27 CN CNA2006800447926A patent/CN101316856A/zh active Pending
- 2006-11-27 AU AU2006319382A patent/AU2006319382A1/en not_active Abandoned
- 2006-11-27 EA EA200801272A patent/EA200801272A1/xx unknown
- 2006-11-27 BR BRPI0619237-8A patent/BRPI0619237A2/pt not_active Application Discontinuation
- 2006-11-27 JP JP2008542680A patent/JP2009517426A/ja active Pending
- 2006-11-27 KR KR1020087015777A patent/KR20080072087A/ko not_active Application Discontinuation
- 2006-11-27 EP EP06829356A patent/EP1957514A1/fr not_active Withdrawn
2008
- 2008-05-20 CR CR9997A patent/CR9997A/xx not_active Application Discontinuation
- 2008-05-29 EC EC2008008482A patent/ECSP088482A/es unknown
- 2008-06-27 ZA ZA200805658A patent/ZA200805658B/xx unknown
- 2008-06-27 NO NO20082918A patent/NO20082918L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ECSP088482A (es)	2008-06-30
CR9997A (fr)	2008-09-22
DE102005057225A1 (de)	2007-05-31
KR20080072087A (ko)	2008-08-05
WO2007062876A1 (fr)	2007-06-07
NO20082918L (no)	2008-06-27
JP2009517426A (ja)	2009-04-30
BRPI0619237A2 (pt)	2011-09-20
CN101316856A (zh)	2008-12-03
AU2006319382A1 (en)	2007-06-07
EA200801272A1 (ru)	2008-10-30
EP1957514A1 (fr)	2008-08-20
CA2630438A1 (fr)	2007-06-07

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