CA2630438A1 - Promedicaments de substances er-beta-selectives, procedes de realisation associes et compositions pharmaceutiques contenant ces composes - Google Patents

Promedicaments de substances er-beta-selectives, procedes de realisation associes et compositions pharmaceutiques contenant ces composes Download PDF

Info

Publication number: CA2630438A1
Authority: CA; Canada
Prior art keywords: beta; trien; estra; group; sulfamoyl
Prior art date: 2005-11-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002630438A

Other languages

English (en)

Inventor

Olaf Peters

Gudrun Reddersen

Ralf Wyrwa

Alexander Hillisch

Walter Elger

Katja Prelle

Peter Droescher

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer Pharma AG

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-11-29

Filing date

2006-11-27

Publication date

2007-06-07

2006-11-27 Application filed by Individual filed Critical Individual

2007-06-07 Publication of CA2630438A1 publication Critical patent/CA2630438A1/fr

Status Abandoned legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P37/02—Immunomodulators
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Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CA002630438A 2005-11-29 2006-11-27 Promedicaments de substances er-beta-selectives, procedes de realisation associes et compositions pharmaceutiques contenant ces composes Abandoned CA2630438A1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE102005057225.1		2005-11-29
DE102005057225A DE102005057225A1 (de)	2005-11-29	2005-11-29	Prodrugs ERß-selektiver Substanzen, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
PCT/EP2006/011728 WO2007062876A1 (fr)	2005-11-29	2006-11-27	Promedicaments de substances er-beta-selectives, procedes de realisation associes et compositions pharmaceutiques contenant ces composes

Publications (1)

Publication Number	Publication Date
CA2630438A1 true CA2630438A1 (fr)	2007-06-07

Family

ID=37909446

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002630438A Abandoned CA2630438A1 (fr)	2005-11-29	2006-11-27	Promedicaments de substances er-beta-selectives, procedes de realisation associes et compositions pharmaceutiques contenant ces composes

Country Status (14)

Country	Link
EP (1)	EP1957514A1 (fr)
JP (1)	JP2009517426A (fr)
KR (1)	KR20080072087A (fr)
CN (1)	CN101316856A (fr)
AU (1)	AU2006319382A1 (fr)
BR (1)	BRPI0619237A2 (fr)
CA (1)	CA2630438A1 (fr)
CR (1)	CR9997A (fr)
DE (1)	DE102005057225A1 (fr)
EA (1)	EA200801272A1 (fr)
EC (1)	ECSP088482A (fr)
NO (1)	NO20082918L (fr)
WO (1)	WO2007062876A1 (fr)
ZA (1)	ZA200805658B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2016539954A (ja)	2013-12-05	2016-12-22	カロファーマエービーＫａｒｏＰｈａｒｍａＡｂ	中皮腫の処置で使用するためのエストロゲン受容体ベータアゴニスト

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL207488B1 (pl) *	2000-04-12	2010-12-31	Schering Ag	Pochodne estra-1,3,5(10)-trienu podstawione w pozycji 8ß, ich zastosowanie oraz kompozycja farmaceutyczna je zawierająca
DE10027887A1 (de) *	2000-05-31	2001-12-13	Jenapharm Gmbh	Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
DE102004025966A1 (de) *	2004-05-21	2005-12-15	Schering Ag	Estradiol-Prodrugs
US7534780B2 (en) *	2004-05-21	2009-05-19	Bayer Schering Pharma Aktiengesellschaft	Estradiol prodrugs

2005
- 2005-11-29 DE DE102005057225A patent/DE102005057225A1/de not_active Ceased
2006
- 2006-11-27 CA CA002630438A patent/CA2630438A1/fr not_active Abandoned
- 2006-11-27 WO PCT/EP2006/011728 patent/WO2007062876A1/fr active Application Filing
- 2006-11-27 CN CNA2006800447926A patent/CN101316856A/zh active Pending
- 2006-11-27 AU AU2006319382A patent/AU2006319382A1/en not_active Abandoned
- 2006-11-27 EA EA200801272A patent/EA200801272A1/xx unknown
- 2006-11-27 BR BRPI0619237-8A patent/BRPI0619237A2/pt not_active Application Discontinuation
- 2006-11-27 JP JP2008542680A patent/JP2009517426A/ja active Pending
- 2006-11-27 KR KR1020087015777A patent/KR20080072087A/ko not_active Application Discontinuation
- 2006-11-27 EP EP06829356A patent/EP1957514A1/fr not_active Withdrawn
2008
- 2008-05-20 CR CR9997A patent/CR9997A/xx not_active Application Discontinuation
- 2008-05-29 EC EC2008008482A patent/ECSP088482A/es unknown
- 2008-06-27 ZA ZA200805658A patent/ZA200805658B/xx unknown
- 2008-06-27 NO NO20082918A patent/NO20082918L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ZA200805658B (en)	2010-01-27
ECSP088482A (es)	2008-06-30
CR9997A (fr)	2008-09-22
DE102005057225A1 (de)	2007-05-31
KR20080072087A (ko)	2008-08-05
WO2007062876A1 (fr)	2007-06-07
NO20082918L (no)	2008-06-27
JP2009517426A (ja)	2009-04-30
BRPI0619237A2 (pt)	2011-09-20
CN101316856A (zh)	2008-12-03
AU2006319382A1 (en)	2007-06-07
EA200801272A1 (ru)	2008-10-30
EP1957514A1 (fr)	2008-08-20

Publication	Publication Date	Title
US20070197488A1 (en)	2007-08-23	Prodrugs of ERbeta-selective substances, process for their production, and pharmaceutical compositions that contain these compounds
US7534780B2 (en)	2009-05-19	Estradiol prodrugs
US5571933A (en)	1996-11-05	Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
RU2339643C2 (ru)	2008-11-27	17 бета-оксиэстратриены
JP5795312B2 (ja)	2015-10-14	１７−ヒドロキシ−１７−ペンタフルオロエチル−エストラ−４，９（１０）−ジエン−１１−アリール誘導体、その製造方法、その誘導体を利用した諸疾患の治療
CN105008382B (zh)	2018-01-30	用于抑制17β‑羟类固醇脱氢酶(AKR1 C3)的雌甾‑1,3,5(10),16‑四烯‑3‑羧酰胺
CA2768453A1 (fr)	2011-01-27	Derives 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-acyloxyalcenylphenyle, procedes de preparation et utilisation pour le traitement de maladies
JP2009215317A (ja)	2009-09-24	ステロイドスルファメート、その製造方法、及びその使用
US20070123500A1 (en)	2007-05-31	Prodrugs of ERbeta-selective substances, processes for their preparation and pharmaceutical compositions comprising these compounds
US20050026891A1 (en)	2005-02-03	Progesterone receptor modulators with increased antigonadotropic activity for female birth control and hormone replacement therapy
PL188079B1 (pl)	2004-12-31	Związek steroidowy o aktywności antykoncepcyjnej i przeciw osteoporozie, kompozycja farmaceutyczna,zastosowanie i sposób wytwarzania 16,17 anelowanych steroidów
ES2286042T3 (es)	2007-12-01	18-nor-esteroides como estrogenos eficaces selectivamente.
CA2564963A1 (fr)	2005-12-01	Promedicaments steroides a effet androgene
JP2007538025A (ja)	2007-12-27	エストラジオールプロドラッグ
CA2630438A1 (fr)	2007-06-07	Promedicaments de substances er-beta-selectives, procedes de realisation associes et compositions pharmaceutiques contenant ces composes
JP2007538027A (ja)	2007-12-27	エストリオール及びエステトロールプロドラッグ類
CA2629587A1 (fr)	2007-06-07	Promedicaments de substances er.beta.-selectives, procedes de realisation associes et compositions pharmaceutiques contenant ces composes
EA008442B1 (ru)	2007-06-29	9α-ЗАМЕЩЁННЫЕ ЭСТРАТРИЕНЫ В КАЧЕСТВЕ ЭСТРОГЕНОВ ИЗБИРАТЕЛЬНОГО ДЕЙСТВИЯ
UA79073C2 (en)	2007-05-25	8- hydrocarbyl-substituted estratrienes for use as selective estrogens, pharmaceutical composition based thereon
US20050282793A1 (en)	2005-12-22	Steroid prodrugs with androgenic action
MX2008006855A (en)	2008-09-02	Prodrugs of er-beta-selective substances method for production thereof and pharmaceutical compositions comprising the same
MX2008006856A (en)	2008-09-02	Prodrug erî²-selective substances, methods for the production thereof and pharmaceutical compositions containing said compounds
KR20070020454A (ko)	2007-02-21	안드로겐 효과를 가지는 스테로이드 프로드러그
GB2195639A (en)	1988-04-13	Polyconjugated androstenediones and process for their preparation

Legal Events

Date	Code	Title	Description
2010-11-29	FZDE	Discontinued