WO2023233398A1

WO2023233398A1 - Herbicidal mixture, herbicidal composition, method, use, and kits for controlling undesirable vegetation

Info

Publication number: WO2023233398A1
Application number: PCT/IL2023/050549
Authority: WO
Inventors: Eti SHARON; Shani SPERLING; Rob BAHRY
Original assignee: Adama Agan Ltd.
Priority date: 2022-05-30
Filing date: 2023-05-29
Publication date: 2023-12-07
Also published as: AR129475A1

Abstract

The present disclosure relates to an herbicidal mixture comprising a first herbicide selected from the group consisting of a photosynthesis inhibitor and a second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor. The present disclosure also relates to an herbicidal composition comprising the herbicidal mixture of the present disclosure and at least one agricultural carrier. The present disclosure also relates to a method, a use, and kits for controlling undesirable vegetation.

Description

HERBICIDAL MIXTURE, HERBICIDAL COMPOSITION, METHOD, USE, AND KITS FOR

CONTROLLING UNDESIRABLE VEGETATION

TECHNICAL FIELD

The present disclosure relates to an herbicidal mixture comprising a first herbicide selected from the group consisting of a photosynthesis inhibitor and a second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor. The present disclosure also relates to an herbicidal composition, which comprises the herbicidal mixture disclosed in the present disclosure, and an agricultural carrier. The present disclosure discloses a method for controlling undesirable vegetation, which includes applying an herbicidally effective amount of the herbicidal mixture or the herbicidal composition disclosed herein to the undesirable vegetation or its locus. The present disclosure also discloses the use of the herbicidal mixture or the herbicidal composition disclosed herein for controlling undesired vegetation. The present disclosure also discloses a kit comprising the herbicidal mixture or the herbicidal composition disclosed herein.

BACKGROUND

In order to obtain high crop efficiency, the control of undesirable vegetation is extremely important. In many cases, although herbicides have an effect on a certain weed spectrum, they do not exhibit efficacy against other types of weeds which are also present in the crops to be protected. Therefore, there is an urgent need to mix two, three or more herbicides. In addition, the application of two, three or more active ingredients of herbicide with different functioning manners may bring about many advantages, such as expanded weed spectrum, reduced application rate, reduced number of applications, and in some cases synergy effect (in which the efficacy increases).

Compared with applying a single herbicide, a mixture of selected herbicides may also have the following advantages, including: (a) enlarging the spectrum of the weeds to be controlled, or extending the control of weeds for a longer period of time; (b) improving crop safety by applying the lowest dosage of the selected multiple herbicides in a combination instead of a single high dosage of one herbicide, and (c) delaying sprouting of the weed species resistant to the selected multiple herbicides (Int. J. Agri. Biol., Vol. 6, No. l, 2004, pp. 209-212).

However, the activity and selectivity of any specific mixture is difficult to predict, since the performance of each single herbicide in the mixture is often affected by the presence of the other herbicide(s). Moreover, the activity of the mixture may also vary significantly depending on chemical properties, plant species, growth stage, environmental conditions, application rate, and so on.

The chemical name of Diquat is 9,10-dihydro-8a,10a-diazoniaphenanthrene, with the following structural

The CAS registry number of Diquat is 2764-72-9, and it is a photosynthesis inhibitor herbicide, and may be used as the dibromide or dichloride salt, to control broad-leaved weeds and grasses.

The chemical name of Glufosinate is 2-amino-4-[hydroxy(methyl)phosphinoyl]butyric acid, and has the following structural formula

and its CAS registry number is 51276-47-2. Glufosinate is an organophosphate herbicide, a glutamine synthetase inhibitor, and may be used as an ammonium salt.

The chemical name of Saflufenacil is

N'-{2-chloro-4-fluoro-5-[l,2,3,6-tetrahydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-l-yl] benzoyl}-N-isopropyl-N-methylsulfamide, and has the following structural formula

and its CAS registry number is 372137-35-4. Saflufenacil is an uracil herbicide, and a PPO inhibitor.

The chemical name of Diuron is 3 -(3, 4-dichlorophenyl)- 1,1 -dimethylurea, and has the following structural formula

and its CAS registry number is 330-54-1. Diuron is an urea herbicide, and a Photosystem II inhibitor.

The chemical name of Amitrole is lH-l,2,4-triazol-3-amine, and has the following structural formula

and its CAS registry number is 61-82-5. Amitrole is a triazole herbicide, and a root elongation inhibitor, and may be used as the HCL salt.

The chemical name of Asulam is methyl sulfanilylcarbamate, and has the following structural formula

and its CAS registry number is 3337-71-1. Asulam is a carbamate herbicide, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, and may be used as the sodium salt.

The chemical name of Imazamox is

2-[(RS)-4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl]-5-methoxymethylnicotinic acid, and has the following structural formula

and its CAS registry number is 114311-32-9. Imazamox is an imidazolinone herbicide, and an Acetolactate Synthase inhibitor, and may be used as a salt.

The chemical name of Pelargonic acid is 1-octanecarboxyic acid, and has the following structural formula

and its CAS registry number is 112-05-0. Pelargonic acid is a fatty acid herbicide.

The chemical name of S-metolachlor is

2-chloro-N-(2-ethyl-6-methylphenyl)-N-((lS)-2-methoxy-l-methylethyl)acetamide, and has the following structural formula

and its CAS registry number is 87392-12-9. S-metolachlor is an acetamide herbicide, and a VLCFA inhibitor.

The chemical name of Flumioxazin is

N-(7-fluoro-3, 4-dihydro-3-oxo-4-prop-2-ynyl-2H-l,4-benzoxazin-6-yl)cy cl ohex-l-ene-l,2-di carbo xamide, and has the following structural formula

and its CAS registry number is 103361-09-7. Flumioxazin is a dicarboximide herbicide, and a PPO inhibitor.

Copper preparation is a multi-site herbicide.

The chemical name of Metribuzin is

4-amino-6-tert-butyl-4,5-dihydro-3-methylthio-l,2,4-triazin-5-one, and has the following structural formula

and its CAS registry number is 21087-64-9. Metribuzin is a triazinone herbicide, and a Photosystem II inhibitor.

The chemical name of Clethodim is

(5RS)-2-{(E)-l-[(2E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylthio)propyl]-3-hydroxycycl ohex-2-en-l-one, and has the following structural formula

and its CAS registry number is 99129-21-2. Clethodim is a cyclohexanedione herbicide, and an ACCase inhibitor.

The chemical name of Propaquizafop is 2-isopropylideneaminooxyethyl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate, and has the following structural formula

and its CAS registry number is 111479-05-1. Propaquizafop is an aryl oxy phenoxy propionate herbicide, and an ACCase inhibitor.

There is a continuing need in the art for herbicidal mixtures, herbicidal compositions, methods, use, and kits for controlling growth of undesirable vegetation.

SUMMARY

According to one aspect, the present disclosure provides an herbicidal mixture comprising a first herbicide selected from the group consisting of a photosynthesis inhibitor and a second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor.

According to another aspect, the present disclosure relates to an herbicidal composition comprising the herbicidal mixture of the present disclosure and at least one agricultural carrier.

According to another aspect, the present disclosure provides a method for controlling undesirable vegetation, which includes applying an herbicidally effective amount of the herbicidal mixture or the herbicidal composition of the present disclosure to the undesirable vegetation or its locus.

According to another aspect, the present disclosure provides a use of the herbicidal mixture or the herbicidal composition of the present disclosure for controlling undesired vegetation.

According to another aspect, the present disclosure provides a kit comprising the herbicidal mixture or the herbicidal composition of the present disclosure. According to another aspect, the present disclosure provides a method for desiccating a crop, which includes applying an herbicidally effective amount of the herbicidal mixture or the herbicidal composition of the present disclosure to the crop.

According to another aspect, the present disclosure provides a use of the herbicidal mixture or the herbicidal composition of the present disclosure for desiccating a crop.

More particularly, the present disclosure provides the following embodiments:

1. A herbicidal mixture comprising a first herbicide selected from the group consisting of a photosynthesis inhibitor and a second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor.

2. The herbicidal mixture of embodiment 1, wherein the first herbicide is selected from the group consisting of Diquat or a salt thereof and Paraquat.

3. The herbicidal mixture of embodiment 2, wherein the first herbicide is Diquat or a salt thereof.

4. The herbicidal mixture of any one of embodiments 1 to 3, wherein Diquat or a salt thereof is in a form of a dichloride or a dibromide.

5. The herbicidal mixture of any one of embodiments 1 to 4, wherein the glutamine synthetase inhibitor is selected from the group consisting of Glufosinate or a salt thereof, bilanafos or phosphinothricin.

6. The herbicidal mixture of embodiment 5, wherein the glutamine synthetase inhibitor is selected from the group consisting of Glufosinate or a salt thereof.

7. The herbicidal mixture of any one of embodiments 1 to 6, wherein the PPO inhibitor is selected from the group consisting of Saflufenacil, Sulfentrazone, Carfentrazone, Trifludimoxazin, Flumioxazin, and Flumipropyn.

8. The herbicidal mixture of embodiment 7, wherein the PPO inhibitor is selected from the group consisting of Saflufenacil and Flumioxazin. 9. The herbicidal mixture of any one of embodiments 1 to 8, wherein the Photosystem II inhibitor is selected from the group consisting of Diuron, Chlorotoluron, Linuron, Isoproturon, Fluometuron, metribuzine, Metamitron, Atrazine, and Simazine.

10. The herbicidal mixture of embodiment 9, wherein the Photosystem II inhibitor is selected from the group consisting of Diuron and metribuzine.

11. The herbicidal mixture of any one of embodiments 1 to 10, wherein the root elongation inhibitor is Amitrole or a salt thereof.

12. The herbicidal mixture of any one of embodiments 1 to 11, wherein the herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate is selected from the group consisting of Asulam or a salt thereof and Carbetamide.

13. The herbicidal mixture of embodiment 12, wherein the herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate is Asulam or a salt thereof.

14. The herbicidal mixture of any one of embodiments 1 to 13, wherein the Acetolactate Synthase inhibitor is selected from the group consisting of Imazamox, Imazapic, Imazaquin, Imazapyr, Imazethapyr, and Imazosulfuron.

15. The herbicidal mixture of embodiment 14, wherein the Acetolactate Synthase inhibitor is Imazamox.

16. The herbicidal mixture of any one of embodiments 1 to 15, wherein the fatty acid is Pelargonic acid.

17. The herbicidal mixture of any one of embodiments 1 to 16, wherein the VLCFA inhibitor is selected from the group consisting of S-metolachlor, Metolachlor, Pyroxasulfone, Flufenacet, Metazachlor, and Dimethenamid.

18. The herbicidal mixture of embodiment 14, wherein the VLCFA inhibitor is S-metolachlor.

19. The herbicidal mixture of any one of embodiments 1 to 18, wherein the multi-site herbicide is a copper preparation.

20. The herbicidal mixture of any one of embodiments 1 to 19, wherein the ACCase inhibitor is selected from the group consisting of Clethodim, Sethoxydim, Propaquizafop, and quizalofop. 21. The herbicidal mixture of embodiment 14, wherein the ACCase inhibitor is selected from the group consisting of Clethodim and Propaquizafop.

22. The herbicidal mixture of embodiment 1, wherein the first herbicide is Diquat or a salt thereof, and the second herbicide is selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop.

23. The herbicidal mixture of any one of embodiments 1 to 22, wherein the weight ratio of the first herbicide to the second herbicide is 1 :400 to 400: 1.

24. The herbicidal mixture of embodiment 23, wherein the weight ratio of the first herbicide to the second herbicide is 1 :200 to 200: 1.

25. The herbicidal mixture of embodiment 23, wherein the weight ratio of the first herbicide to the second herbicide is 1 : 100 to 100: 1.

26. The herbicidal mixture of embodiment 23, wherein the weight ratio of the first herbicide to the second herbicide is 1 :50 to 50: 1.

27. The herbicidal mixture of embodiment 23, wherein the weight ratio of the first herbicide to the second herbicide is 1 :20 to 20: 1.

28. The herbicidal mixture of embodiment 23, wherein the weight ratio of the first herbicide to the second herbicide is 1 : 10 to 10: 1.

29. The herbicidal mixture of embodiment 23, wherein the weight ratio of the first herbicide to the second herbicide is 1 :5 to 5: 1.

30. The herbicidal mixture of embodiment 23, wherein the weight ratio of the first herbicide to the second herbicide is 1 : 1.

31. The herbicidal mixture of any one of embodiments 1 to 30 wherein the first herbicide and the second herbicide are applied jointly or in a succession.

32. The herbicidal mixture of any one of embodiments 1 to 31, wherein the total application rate of the first and second herbicides are 1-20000 g ai/ha.

33. The herbicidal mixture of any one of embodiments 1 to 32, wherein the herbicidal mixture is synergistic.

34. The herbicidal mixture of any one of embodiments 1 to 33, wherein the herbicidal mixture is consisted of the first herbicide and the second herbicide. 35. The herbicidal mixture of embodiment 34, wherein the herbicidal mixture is consisted of the first herbicide Diquat or a salt thereof and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop.

36. A herbicidal composition comprising the herbicidal mixture of any one of embodiments 1 to 35, and an agriculturally acceptable carrier.

37. The herbicidal composition of embodiment 36, further comprising at least one surfactant.

38. A method of controlling undesired vegetation comprising applying to the undesirable vegetation or its locus a herbicidally effective amount of the herbicidal mixture of any one of embodiments 1 to 35 or the herbicidal composition of any one of embodiments 36-37.

39. The method of embodiment 38 wherein the undesired vegetation is controlled in a crop selected from the group consisting of potatoes, soybean, corn, cereals, cotton, OSR, Field Pea, Faba/Broad Bean, Chickpea, Lentil, and Lupin.

40. The method of embodiment 38 or 39 wherein the undesired vegetation is selected from the group consisting of Fleabane (Conyza bonariensis), Indian hedge mustard (Sisymbrium orientale), Sowthistle/ Milk thistle (Sonchus oleraceus), Prickly lettuce (Lactuca serriola), Amaranthus, Barley Grass, Barnyard Grass, Capeweed, Cobbler s ’ , and the combination thereof

41. Use of the herbicidal mixture of any one of embodiments 1 to 35 or the herbicidal composition of any one of embodiments 36-37 for controlling undesired vegetation.

42. A kit comprising the herbicidal mixture of any one of embodiments 1 to 35 or the herbicidal composition of any one of embodiments 36-37.

43. A method of desiccating a crop comprising applying to the crop an effective amount of the herbicidal mixture of any one of embodiments 1 to 35 or the herbicidal composition of any one of embodiments 36-37.

44. The method of embodiment 43 wherein the crop selected from the group consisting of canola, potatoes, field peas, and lentils.

45. Use of the herbicidal mixture of any one of embodiments 1 to 35 or the herbicidal composition of any one of embodiments 36-37 for desiccating a crop. DETAILED DESCRIPTION

Before elaborating the present disclosure in detail, it may be helpful to provide definitions of some terms used herein. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the art to which the present disclosure belongs.

As used herein, the phrase "an agriculturally acceptable carrier " refers to a carrier known in the art and accepted for forming a variety of formulations for agricultural or horticultural application.

As used herein, the term "plant" or "crop" includes whole plants, plant organs (e.g., leaves, stems, branches, roots, trunks, wickers, twigs, fruits, etc.), plant cells or plant seeds. This term also includes plant crops such as fruits. In another embodiment, the term "plant" or "vegetation" may include the propagation materials of the plant, and the propagation materials may include all reproductive parts of the plant, e.g., seeds and vegetative plant materials, such as cuttings and various tubers that may be used for plant propagation. The plants include seed, tuber, spore, carmus, bulb, rhizome, sprout, stolon, bud and other parts of plants including seedling and young plant which are transplanted after germinating or sprouting from the soil.

As used herein, the term "locus" includes not only places where undesirable vegetation (e.g., weeds) may have grown, but also places where undesirable vegetation (e.g., weeds) has not yet appeared, and the cultivation areas.

As used herein, the term " post-emergence" refers to the application of an herbicidal mixture or a herbicidal composition to undesirable vegetation (e.g., weeds) sprouting from the soil, and the term "pre-emergence " refers to the application of an herbicidal mixture or a herbicidal composition to the locus, weeds, or soil before the undesirable vegetation (e.g., weeds) sprouting from the soil.

As used herein, the term "controlling undesirable vegetation" refers to disturbing the normal growth and development of undesirable vegetation. Various examples of controlling activities include, but are not limited to: inhibiting root growth, inhibiting sprout growth, inhibiting sprouting, inhibiting seed production, or reducing the biomass of weeds.

As used herein, the term "effective amount" means that the amount of the active ingredient is sufficient to achieve a good level of control when it is ingested, contacted, or perceived. As used herein, the term "herbicidally effective amount" refers to the amount of the active ingredient that produces herbicidal effect. As used herein, the term "herbicidally effective application rate" refers to the application rate of the active ingredient that produces herbicidal effect.

As used herein, the term "synergistic" means the combined effect of the active ingredients is greater than the sum of the effects of each individual ingredient. The term "synergistically effective amount" is an amount exhibiting an herbicidal activity greater than the sum of the herbicidal activities of the individual components.

As used herein, the term "mixture" or "composition" refers to but not limited to any combination of physical forms, e.g., blends, solutions, or alloys.

As used herein, the term "ha" refers to hectares.

As used herein, the term "ai" refers to active ingredient.

The term "surfactant" as used herein refers to an agriculturally acceptable material providing emulsification, stability, spreading, wetting, dispersibility, or other surface modification properties.

Unless otherwise indicated, the singular forms "a" and "an" as used herein include both the singular and the plural forms. Therefore, the terms "a", "an" or "at least one" may be used interchangeably in the present disclosure.

Throughout the application, the description of various embodiments uses the term "include (or comprise)"; however, those skilled in the art will understand that in some specific cases, the language "substantially consists of' or "consists of' may be used interchangeably to describe embodiments. The term "consisting of' means that the mixture or composition before the term comprises only the components listed after the term and no longer comprises other components, but may comprise impurities, and the impurities are only allowed to exist in a usual amount.

In order to better understand the teachings of the present disclosure, and in no way limiting the scope of the teachings, unless otherwise specified, all the numerical values, percentages or ratios, reaction conditions, and other numerical values used in the specification and schemes will be understood as being modified by the term "about" in all cases. Therefore, unless there is an indication to the contrary, the numerical parameters proposed in the following description and solutions are approximate values, and may be changed depending on the desired properties to be obtained. At the very least, each numerical parameter should be interpreted at least based on the value of the reported significant figures and by applying the usual rounding technique. In this regard, the use of the term "about" as used herein specifically comprises a range value of ±10% of the specified value. In addition, all ranges related to the same composition or characteristic of the present disclosure formed by end points (including the end points, and also including all intermediate points and ranges), may be independently combined.

First Aspect

In the first aspect, the present disclosure provides a herbicidal mixture comprising a first herbicide selected from the group consisting of a photosynthesis inhibitor and a second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor. It is found that, compared to the weed control expected to be observed on the basis of two individual herbicides, the herbicidal mixture may provide a broader spectrum of weed control, a reduced dosage of individual herbicide, or a synergistic herbicidal effect.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is selected from the group consisting of Diquat or a salt thereof and Paraquat, more specifically Diquat or a salt thereof. In one embodiment of the present disclosure, in the herbicidal mixture, Diquat or a salt thereof is in a form of a dichloride or a dibromide salt.

In one embodiment of the present disclosure, in the herbicidal mixture, the glutamine synthetase inhibitor is selected from the group consisting of Glufosinate or a salt thereof, bilanafos or phosphinothricin, more specifically Glufosinate or a salt thereof. In one embodiment of the present disclosure, in the herbicidal mixture, Glufosinate or a salt thereof is in a form of an ammonium salt.

In one embodiment of the present disclosure, in the herbicidal mixture, the PPO inhibitor is selected from the group consisting of Saflufenacil, Sulfentrazone, Carfentrazone, Trifludimoxazin, Flumioxazin, and Flumipropyn. In one embodiment of the present disclosure, in the herbicidal mixture, the PPO inhibitor is selected from the group consisting of Saflufenacil and Flumioxazin.

In one embodiment of the present disclosure, in the herbicidal mixture, the Photosystem II inhibitor is selected from the group consisting of Diuron, Chlorotoluron, Linuron, Isoproturon, Fluometuron, metribuzine, Metamitron, Atrazine, and Simazine. In one embodiment of the present disclosure, in the herbicidal mixture, the Photosystem II inhibitor is selected from the group consisting of Diuron and metribuzine. In one embodiment of the present disclosure, in the herbicidal mixture, the root elongation inhibitor is Amitrole or a salt thereof. In one embodiment of the present disclosure, in the herbicidal mixture, Amitrole or a salt thereof is in a form of an HCL salt.

In one embodiment of the present disclosure, in the herbicidal mixture, the herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate is selected from the group consisting of Asulam or a salt thereof and Carbetamide, more specifically Asulam or a salt thereof. In one embodiment of the present disclosure, in the herbicidal mixture, Asulam or a salt thereof is in a form of sodium salt.

In one embodiment of the present disclosure, in the herbicidal mixture, the Acetolactate Synthase inhibitor is selected from the group consisting of Imazamox, Imazapic, Imazaquin, Imazapyr, Imazethapyr, and Imazosulfuron, more specifically Imazamox.

In one embodiment of the present disclosure, in the herbicidal mixture, the fatty acid is Pelargonic acid.

In one embodiment of the present disclosure, in the herbicidal mixture, the VLCFA inhibitor is selected from the group consisting of S-metolachlor, Metolachlor, Pyroxasulfone, Flufenacet, Metazachlor, and Dimethenamid, more specifically S-metolachlor.

In one embodiment of the present disclosure, in the herbicidal mixture, the multi-site herbicide is a copper preparation. In one embodiment of the present disclosure, in the herbicidal mixture, the copper preparation may be: a: Copper Ethanolamine Complex, for example those from AGROS; b.

Bordeaux mixture, for example those made by adding copper sulfate and calcium hydroxide to water; c. Fixed Copper Sulfate; d. Copper Hydroxide; e. Copper Oxide; f. Copper Octanoate; g.

Copper Ammonium Carbonate; h. Copper Oxychloride, and combinations thereof.

In one embodiment of the present disclosure, in the herbicidal mixture, the ACCase inhibitor is selected from the group consisting of Clethodim, Sethoxydim, Propaquizafop, and quizalofop. In one embodiment of the present disclosure, in the herbicidal mixture, the ACCase inhibitor is selected from the group consisting of Clethodim and Propaquizafop.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, and the second herbicide is selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide and the second herbicide are present in synergistic herbicidally effective amounts. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 :400 to 400: 1. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 :200 to 200:1. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 : 100 to 100: 1. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 :50 to 50: 1. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 :20 to 20: 1. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 : 10 to 10:1. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 :5 to 5: 1. In one embodiment of the present disclosure, in the herbicidal mixture, the weight ratio of the first herbicide to the second herbicide is 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Glufosinate or a salt thereof, and the weight ratio of Diquat or a salt thereof to Glufosinate or a salt thereof is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Glufosinate or a salt thereof is 1 :200 to 200:1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20: 1, l : 10 to 10:1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Glufosinate or a salt thereof, and the weight ratio of Diquat or a salt thereof to Glufosinate or a salt thereof is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Glufosinate or a salt thereof is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Glufosinate or a salt thereof is (1-400): (1-400), in the relative amount range (1-400) for Glufosinate or a salt thereof, the relative amount of Glufosinate or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Glufosinate or a salt thereof may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Saflufenacil, and the weight ratio of Diquat or a salt thereof to Saflufenacil is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Saflufenacil is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1:50 to 50: 1, 1 :20 to 20:1, 1: 10 to 10:1, 1:5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Saflufenacil, and the weight ratio of Diquat or a salt thereof to Saflufenacil is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Saflufenacil is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Saflufenacil is (1-400): (1-400), in the relative amount range (1-400) for Saflufenacil, the relative amount of Saflufenacil may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Saflufenacil may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180). In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Diuron, and the weight ratio of Diquat or a salt thereof to Diuron is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Diuron is 1 :200 to 200:1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20:1, 1 : 10 to 10: 1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Diuron, and the weight ratio of Diquat or a salt thereof to Diuron is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Diuron is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Diuron is (1-400): (1-400), in the relative amount range (1-400) for Diuron, the relative amount of Diuron may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Diuron may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Amitrole or a salt thereof, and the weight ratio of Diquat or a salt thereof to Amitrole or a salt thereof is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Amitrole or a salt thereof is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20: 1, l : 10 to 10:1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Amitrole or a salt thereof, and the weight ratio of Diquat or a salt thereof to Amitrole or a salt thereof is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Amitrole or a salt thereof is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Amitrole or a salt thereof is (1-400): (1-400), in the relative amount range (1-400) for Amitrole or a salt thereof, the relative amount of Amitrole or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Amitrole or a salt thereof may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Asulam or a salt thereof, and the weight ratio of Diquat or a salt thereof to Asulam or a salt thereof is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Asulam or a salt thereof is 1 :200 to 200:1, 1: 100 to 100:1, 1 :50 to 50: 1, 1 :20 to 20: 1, l : 10 to 10: 1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Asulam or a salt thereof, and the weight ratio of Diquat or a salt thereof to Asulam or a salt thereof is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Asulam or a salt thereof is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Asulam or a salt thereof is (1-400): (1-400), in the relative amount range (1-400) for Asulam or a salt thereof, the relative amount of Asulam or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Asulam or a salt thereof may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Imazamox, and the weight ratio of Diquat or a salt thereof to Imazamox is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Imazamox is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20: 1, 1 : 10 to 10: 1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Imazamox, and the weight ratio of Diquat or a salt thereof to Imazamox is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Imazamox is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Imazamox is (1-400): (1-400), in the relative amount range (1-400) for Imazamox, the relative amount of Imazamox may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Imazamox may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Pelargonic acid, and the weight ratio of Diquat or a salt thereof to Pelargonic acid is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Pelargonic acid is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1 :50 to 50:1, 1:20 to 20:1, 1: 10 to 10: 1, l :5 to 5: l, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Pelargonic acid, and the weight ratio of Diquat or a salt thereof to Pelargonic acid is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Pelargonic acid is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Pelargonic acid is (1-400): (1-400), in the relative amount range (1-400) for Pelargonic acid, the relative amount of Pelargonic acid may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Pelargonic acid may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is S-metolachlor, and the weight ratio of Diquat or a salt thereof to S-metolachlor is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to S-metolachlor is 1 :200 to 200: 1, 1 :100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20: 1, 1 : 10 to 10:1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is S-metolachlor, and the weight ratio of Diquat or a salt thereof to S-metolachlor is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to S-metolachlor is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to S-metolachlor is (1-400): (1-400), in the relative amount range (1-400) for S-metolachlor, the relative amount of S-metolachlor may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to S-metolachlor may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Flumioxazin, and the weight ratio of Diquat or a salt thereof to Flumioxazin is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Flumioxazin is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20: 1, 1 : 10 to 10: 1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Flumioxazin, and the weight ratio of Diquat or a salt thereof to Flumioxazin is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Flumioxazin is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Flumioxazin is (1-400): (1-400), in the relative amount range (1-400) for Flumioxazin, the relative amount of Flumioxazin may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Flumioxazin may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is a Copper preparation, and the weight ratio of Diquat or a salt thereof to a Copper preparation is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to a Copper preparation is 1 :200 to 200: 1, 1 :100 to 100:1, 1:50 to 50:1, 1:20 to 20: 1, l : 10 to 10: 1, l :5 to 5: l, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is a Copper preparation, and the weight ratio of Diquat or a salt thereof to a Copper preparation is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to a Copper preparation is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to a Copper preparation is (1-400): (1-400), in the relative amount range (1-400) for a Copper preparation, the relative amount of a Copper preparation may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to a Copper preparation may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Metribuzin, and the weight ratio of Diquat or a salt thereof to Metribuzin is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Metribuzin is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20: 1, 1 : 10 to 10: 1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Metribuzin, and the weight ratio of Diquat or a salt thereof to Metribuzin is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Metribuzin is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Metribuzin is (1-400): (1-400), in the relative amount range (1-400) for Metribuzin, the relative amount of Metribuzin may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Metribuzin may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Clethodim, and the weight ratio of Diquat or a salt thereof to Clethodim is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Clethodim is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20: 1, 1 : 10 to 10: 1, 1 :5 to 5: 1, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Clethodim, and the weight ratio of Diquat or a salt thereof to Clethodim is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Clethodim is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Clethodim is (1-400): (1-400), in the relative amount range (1-400) for Clethodim, the relative amount of Clethodim may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Clethodim may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Propaquizafop, and the weight ratio of Diquat or a salt thereof to Propaquizafop is 1 :400 to 400: 1. In this embodiment, the weight ratio of Diquat or a salt thereof to Propaquizafop is 1 :200 to 200: 1, 1 : 100 to 100: 1, 1 :50 to 50: 1, 1 :20 to 20:1, 1 : 10 to 10: 1, l :5 to 5: l, or 1 : 1.

In one embodiment of the present disclosure, in the herbicidal mixture, the first herbicide is Diquat or a salt thereof, the second herbicide is Propaquizafop, and the weight ratio of Diquat or a salt thereof to Propaquizafop is (1-400): (1-400). When the weight ratio of Diquat or a salt thereof to Propaquizafop is (1-400): (1-400), in the relative amount range (1-400) for Diquat or a salt thereof, the relative amount of Diquat or a salt thereof may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-300), (60-250), (50-290), (45-180), (60-180), etc. When the weight ratio of Diquat or a salt thereof to Propaquizafop is (1-400): (1-400), in the relative amount range (1-400) for Propaquizafop, the relative amount of Propaquizafop may be 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 100, 110, 120, 130, 140, 150, 160, 170, 180, 190, 200, 210, 220, 230, 240, 250, 260, 270, 280, 290, 300, 310, 320, 330, 340, 350, 360, 370, 380, 390, 400; and any relative amount range formed by any two of the above mentioned relative amounts as two ends, such as (15-350), (20-200), (60-250), (50-290), (45-180), (60-180), etc. For example, the weight ratio of Diquat or a salt thereof to Propaquizafop may be (15-350): (20-200), (45-180): (60-250), or (50-290): (45-180).

In one embodiment of the present disclosure, the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor are applied in combination or sequentially. In one example, the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor are separately prepared, and each of them is applied as it is, or diluted to a predetermined concentration for application. In another example, the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor are separately prepared, and after being diluted to a predetermined concentration if necessary, they are mixed and then applied. In another example, the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor are formulated together, and then applied as it is, or diluted to a predetermined concentration for application.

In one embodiment of the present disclosure, Diquat or a salt thereof as the first herbicide and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop are applied in combination or sequentially. In one example, Diquat or a salt thereof as the first herbicide and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop are separately prepared, and each of them is applied as it is, or diluted to a predetermined concentration for application. In another example, Diquat or a salt thereof as the first herbicide and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop are separately prepared, and after being diluted to a predetermined concentration if necessary, they are mixed and then applied. In another example, Diquat or a salt thereof as the first herbicide and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop are formulated together, and then applied as it is, or diluted to a predetermined concentration for application.

The herbicidally effective application rate of the first and second herbicides generally varies with various conditions, e.g., the type of formulation, weather conditions, type of crops, and type of weeds. In one embodiment of the present disclosure, the total application rate of the first and second herbicides may be 1 to 20000 grams of active ingredient per hectare (g ai/ha). In the range of 1-20000 g ai/ha, the total application rate of the first and second herbicides may be 1 g ai/ha, 2 g ai/ha, 3 g ai/ha, 4 g ai/ha, 5 g ai/ha, 6 g ai/ha, 7 g ai/ha, 8 g ai/ha, 9 g ai/ha, 10 g ai/ha, 11 g ai/ha, 12 g ai/ha, 13 g ai/ha, 14 g ai/ha, 15 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha, 2500 g ai/ha, 3000 g ai/ha, 3500 g ai/ha, 4000 g ai/ha, 4500 g ai/ha, 5000 g ai/ha, 5500 g ai/ha, 6000 g ai/ha, 6500 g ai/ha, 7000 g ai/ha, 7500 g ai/ha, 8000 g ai/ha, 8500 g ai/ha, 9000 g ai/ha, 9500 g ai/ha, 10000 g ai/ha, 10500 g ai/ha, 11000 g ai/ha, 11500 g ai/ha, 12000 g ai/ha, 13000 g ai/ha, 14000 g ai/ha, 15000 g ai/ha, 16000 g ai/ha, 17000 g ai/ha, 18000 g ai/ha, 19000 g ai/ha, 20000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends.

In one embodiment of the present disclosure, the first herbicide is Diquat or a salt thereof, and the second herbicide is selected from the group consisting of Glufosinate or a salt thereof, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, Metribuzin, Clethodim, and Propaquizafopthe, the total application rate of the first and second herbicides may be 50-2000 grams of active ingredient per hectare (g ai/ha). In the range of 50-2000 g ai/ha, the total application rate of the first and second herbicides may be 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends.

In one embodiment of the present disclosure, the first herbicide is Diquat or a salt thereof, and the second herbicide is Saflufenacil, the total application rate of the first and second herbicides may be 10-120 grams of active ingredient per hectare (g ai/ha). In the range of 10-120 g ai/ha, the total application rate of the first and second herbicides may be 10 g ai/ha, 11 g ai/ha, 12 g ai/ha, 13 g ai/ha, 14 g ai/ha, 15 g ai/ha, 20 g ai/ha, 25 g ai/ha, 30 g ai/ha, 35 g ai/ha, 40 g ai/ha, 45 g ai/ha, 50 g ai/ha, 55 g ai/ha, 60 g ai/ha, 65 g ai/ha, 70 g ai/ha, 75 g ai/ha, 80 g ai/ha, 85 g ai/ha, 90 g ai/ha, 95 ai/ha, 100 ai/ha, 105 ai/ha, 110 ai/ha, 115 ai/ha, 120 ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends.

In one embodiment of the present disclosure, the first herbicide is Diquat or a salt thereof, and the second herbicide is Copper preparation, the total application rate of the first and second herbicides may be 2000-12000 grams of active ingredient per hectare (g ai/ha). In the range of 2000-12000 g ai/ha, the total application rate of the first and second herbicides may be 2000 g ai/ha, 2500 g ai/ha, 3000 g ai/ha, 3500 g ai/ha, 4000 g ai/ha, 4500 g ai/ha, 5000 g ai/ha, 5500 g ai/ha, 6000 g ai/ha, 6500 g ai/ha, 7000 g ai/ha, 7500 g ai/ha, 8000 g ai/ha, 8500 g ai/ha, 9000 g ai/ha, 9500 g ai/ha, 10000 g ai/ha, 10500 g ai/ha, 11000 g ai/ha, 11500 g ai/ha, 12000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends.

In one embodiment of the present disclosure, the application rate of the fist herbicide is 50-2000 g ai/ha. In the range of 50-2000 g ai/ha, the application rate of the first herbicide may be 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of the fist herbicide is 100-1500 g ai/ha, 200-1000 g ai/ha, 200-800 g ai/ha, 200-500 g ai/ha, 300-500 g ai/ha, 400 g ai/ha.

In one embodiment of the present disclosure, the application rate of the second herbicide is 1-20000 g ai/ha. In the range of 1-20000 g ai/ha, the application rate of the second herbicide may be 1 g ai/ha, 2 g ai/ha, 3 g ai/ha, 4 g ai/ha, 5 g ai/ha, 6 g ai/ha, 7 g ai/ha, 8 g ai/ha, 9 g ai/ha, 10 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha, 3000 g ai/ha, 4000 g ai/ha, 4500 g ai/ha, 5000 g ai/ha, 6000 g ai/ha, 7000 g ai/ha, 8000 g ai/ha, 9000 g ai/ha, 10000 g ai/ha, 11000 g ai/ha, 12000 g ai/ha, 13000 g ai/ha, 14000 g ai/ha, 15000 g ai/ha, 16000 g ai/ha, 17000 g ai/ha, 18000 g ai/ha, 19000 g ai/ha, 20000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of the second herbicide is 100-1500 g ai/ha, 200-1000 g ai/ha, 200-800 g ai/ha, 200-500 g ai/ha, 300-500 g ai/ha, 600-18000 g ai/ha, 400 g ai/ha, 1000-15000 g ai/ha, 2000-10000 g ai/ha, 4000-5000 g ai/ha, 4500 g ai/ha.

In one embodiment of the present disclosure, the application rate of Diquat or a salt thereof is 50-2000 g ai/ha. In the range of 50-2000 g ai/ha, the application rate of Diquat or a salt thereof may be 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Diquat or a salt thereof is 100-1500 g ai/ha, 200-1000 g ai/ha, 200-800 g ai/ha, 200-500 g ai/ha, 300-500 g ai/ha, 400 g ai/ha.

In one embodiment of the present disclosure, the application rate of Glufosinate or a salt thereof is 50-2000 g ai/ha. In the range of 50-2000 g ai/ha, the application rate of Glufosinate or a salt thereof may be 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Glufosinate or a salt thereof is 100-1500 g ai/ha, 200-1000 g ai/ha, 200-800 g ai/ha, 200-500 g ai/ha, 300-500 g ai/ha, 400 g ai/ha.

In one embodiment of the present disclosure, the application rate of Saflufenacil is 1-2000 g ai/ha. In the range of 1-2000 g ai/ha, the application rate of Saflufenacil may be 1 g ai/ha, 2 g ai/ha, 3 g ai/ha, 4 g ai/ha, 5 g ai/ha, 6 g ai/ha, 7 g ai/ha, 8 g ai/ha, 9 g ai/ha, 10 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Saflufenacil is 10-1000 g ai/ha, 15-500 g ai/ha, 20-100 g ai/ha, 25 g ai/ha.

In one embodiment of the present disclosure, the application rate of Diuron is 50-4000 g ai/ha. In the range of 50-4000 g ai/ha, the application rate of Diuron may be 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha, 2100 g ai/ha, 2200 g ai/ha, 2300 g ai/ha, 2400 g ai/ha, 2500 g ai/ha, 2600 g ai/ha, 2700 g ai/ha, 2800 g ai/ha, 2900 g ai/ha, 3000 g ai/ha, 3100 g ai/ha, 3200 g ai/ha, 3300 g ai/ha, 3400 g ai/ha, 3500 g ai/ha, 3600 g ai/ha, 3700 g ai/ha, 3800 g ai/ha, 3900 g ai/ha, 4000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Diuron is 100-3000 g ai/ha, 200-2000 g ai/ha, 400-1500 g ai/ha, 700-900 g ai/ha, 800 g ai/ha. In one embodiment of the present disclosure, the application rate of Amitrole or a salt thereof or a salt is 50-2000 g ai/ha. In the range of 50-2000 g ai/ha, the application rate of Amitrole or a salt thereof or a salt may be 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Amitrole or a salt thereof is 60-2000 g ai/ha, 100-1500 g ai/ha, 200-1200 g ai/ha, 400-600 g ai/ha, 500 g ai/ha.

In one embodiment of the present disclosure, the application rate of Asulam or a salt thereof or a salt is 100-10000 g ai/ha. In the range of 100-10000 g ai/ha, the application rate of Asulam or a salt thereof or a salt may be 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha, 2500 g ai/ha, 3000 g ai/ha, 3500 g ai/ha, 4000 g ai/ha, 4500 g ai/ha, 5000 g ai/ha, 5500 g ai/ha, 6000 g ai/ha, 6500 g ai/ha, 7000 g ai/ha, 7500 g ai/ha, 8000 g ai/ha, 8500 g ai/ha, 9000 g ai/ha, 9500 g ai/ha, 10000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Asulam or a salt thereof is 200-8000 g ai/ha, 300-6400 g ai/ha, 600-3200 g ai/ha, 1300-1600 g ai/ha, 1500 g ai/ha.

In one embodiment of the present disclosure, the application rate of Imazamox is 1-2000 g ai/ha. In the range of 1-2000 g ai/ha, the application rate of Imazamox may be 1 g ai/ha, 2 g ai/ha, 3 g ai/ha, 4 g ai/ha, 5 g ai/ha, 6 g ai/ha, 7 g ai/ha, 8 g ai/ha, 9 g ai/ha, 10 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Imazamox is 15-1000 g ai/ha, 20-200 g ai/ha, 30-100 g ai/ha, 40-60 g ai/ha, 50 g ai/ha. In one embodiment of the present disclosure, the application rate of Pelargonic acid is 100-10000 g ai/ha. In the range of 100-2000 g ai/ha, the application rate of Pelargonic acid may be 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha, 2500 g ai/ha, 3000 g ai/ha, 3500 g ai/ha, 4000 g ai/ha, 4500 g ai/ha, 5000 g ai/ha, 5500 g ai/ha, 6000 g ai/ha, 6500 g ai/ha, 7000 g ai/ha, 7500 g ai/ha, 8000 g ai/ha, 8500 g ai/ha, 9000 g ai/ha, 9500 g ai/ha, 10000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Pelargonic acid is 150-8000 g ai/ha, 250-4000 g ai/ha, 500-2000 g ai/ha, 900-1100 g ai/ha, 1000 g ai/ha.

In one embodiment of the present disclosure, the application rate of S-metolachlor is 100-10000 g ai/ha. In the range of 100-10000 g ai/ha, the application rate of S-metolachlor may be 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha, 2500 g ai/ha, 3000 g ai/ha, 3500 g ai/ha, 4000 g ai/ha, 4500 g ai/ha, 5000 g ai/ha, 5500 g ai/ha, 6000 g ai/ha, 6500 g ai/ha, 7000 g ai/ha, 7500 g ai/ha, 8000 g ai/ha, 8500 g ai/ha, 9000 g ai/ha, 9500 g ai/ha, 10000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of S-metolachlor is 150-8000 g ai/ha, 250-4000 g ai/ha, 500-2000 g ai/ha, 900-1100 g ai/ha, 1000 g ai/ha.

In one embodiment of the present disclosure, the application rate of Flumi oxazin is 1-2000 g ai/ha. In the range of 1-2000 g ai/ha, the application rate of Flumioxazin may be 1 g ai/ha, 2 g ai/ha, 3 g ai/ha, 4 g ai/ha, 5 g ai/ha, 6 g ai/ha, 7 g ai/ha, 8 g ai/ha, 9 g ai/ha, 10 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Flumioxazin is 5-1000 g ai/ha, 10-600 g ai/ha, 20-300 g ai/ha, 30-150 g ai/ha, 50-70 g ai/ha, 60 g ai/ha. In one embodiment of the present disclosure, the application rate of Copper preparation is 100-20000 g ai/ha. In the range of 100-20000 g ai/ha, the application rate of Copper preparation may be 100g ai/ha, 200g ai/ha, 300g ai/ha, 400g ai/ha, 500g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1200 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 2000 g ai/ha, 3000 g ai/ha, 4000 g ai/ha, 4500 g ai/ha, 5000 g ai/ha, 6000 g ai/ha, 7000 g ai/ha, 8000 g ai/ha, 9000 g ai/ha, 10000 g ai/ha, 11000 g ai/ha, 12000 g ai/ha, 13000 g ai/ha, 14000 g ai/ha, 15000 g ai/ha, 16000 g ai/ha, 17000 g ai/ha, 18000 g ai/ha, 19000 g ai/ha, 20000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Clethodim is 600-18000 g ai/ha, 1000-15000 g ai/ha, 2000-10000 g ai/ha, 4000-5000 g ai/ha, 4500 g ai/ha.

In one embodiment of the present disclosure, the application rate of Metribuzin is 10-2000 g ai/ha. In the range of 10-2000 g ai/ha, the application rate of Metribuzin may be 10 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Metribuzin is 20-1200 g ai/ha, 30-600 g ai/ha, 50-300 g ai/ha, 100-150 g ai/ha, 120 g ai/ha.

In one embodiment of the present disclosure, the application rate of Clethodim is 1-2000 g ai/ha. In the range of 1-2000 g ai/ha, the application rate of Clethodim may be 1 g ai/ha, 2 g ai/ha, 3 g ai/ha, 4 g ai/ha, 5 g ai/ha, 6 g ai/ha, 7 g ai/ha, 8 g ai/ha, 9 g ai/ha, 10 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Clethodim is 5-400 g ai/ha, 10-200 g ai/ha, 20-120 g ai/ha, 40-60 g ai/ha, 50 g ai/ha.

In one embodiment of the present disclosure, the application rate of Propaquizafop is 1-2000 g ai/ha. In the range of 1-2000 g ai/ha, the application rate of Propaquizafop may be 1 g ai/ha, 2 g ai/ha, 3 g ai/ha, 4 g ai/ha, 5 g ai/ha, 6 g ai/ha, 7 g ai/ha, 8 g ai/ha, 9 g ai/ha, 10 g ai/ha, 20 g ai/ha, 30 g ai/ha, 40 g ai/ha, 50 g ai/ha, 60 g ai/ha, 70 g ai/ha, 80 g ai/ha, 90 g ai/ha, 100 g ai/ha, 120 g ai/ha, 140 g ai/ha, 150 g ai/ha, 200 g ai/ha, 300 g ai/ha, 400 g ai/ha, 500 g ai/ha, 600 g ai/ha, 700 g ai/ha, 800 g ai/ha, 900 g ai/ha, 1000 g ai/ha, 1100 g ai/ha, 1200 g ai/ha, 1300 g ai/ha, 1400 g ai/ha, 1500 g ai/ha, 1600 g ai/ha, 1700 g ai/ha, 1800 g ai/ha, 1900 g ai/ha, 2000 g ai/ha; and any application rate range formed by any two of the above mentioned application rates as two ends. For example, the application rate of Propaquizafop is 5-400 g ai/ha, 10-200 g ai/ha, 20-120 g ai/ha, 40-60 g ai/ha, 50 g ai/ha.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of the first herbicide to that of the second herbicide is 1:400 to 400: 1, 1:200 to 200:1, 1:100 to 100:1, 1:50 to 50:1, 1:20 to 20:1, 1:10 to 10:1, 1:5 to 5:1, 1:2 to 2:1, or 1:1.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Glufosinate or a salt thereof or a salt is 1 : 100 to 100: 1, 1:50 to 50:1, 1:20 to 20:1, 1:10 to 10:1, l:5to5:l, 1:2 to 2:1, or 1:1.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Saflufenacil is 1:100 to 400: 1, 1:50 to 200:1, 1:20 to 100:1, 1:10 to 50:1, 1:5 to 30:1, 1:1 to 20:1, 10:1 to 20:1, or 16:1.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Diuron is 1:100 to 100: 1, 1:50 to 50:1, 1:20 to 20:1, 1:10 to 10:1, l:5to5:l, l:3to3:l, 1:3 to 1:1, or 1:2.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Amitrole or a salt thereof or a salt is 1:100 to 100: 1, 1:50 to 50:1, 1:20 to 20:1, 1:10 to 10:1, l:5to5:l, 1:2 to 2:1, 1:2 to 1:1, or 1:1.25.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Asulam or a salt thereof or a salt is 1 :400 to 100: 1, 1:200 to 50:1, 1:100 to 20:1, 1:50 to 10:1, l:20to5:l, l:10to2:l, 1:8 to 1:1, or 1:4.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Imazamox is 1:100 to 400: 1, 1:50 to 200:1, 1:20 to 100:1, 1:10 to 50:1, 1:1 to 20:1, 10:1 to 20:1, or 8:1. In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Pelargonic acid is 1:100 to 100: 1, 1:50 to 50:1,

1:20 to 20:1, 1:10 to 10:1, l:5to5:l, 1:3 to 2:1, 1:3 to 1:1, or 1:2.5.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of S-metolachlor is 1:100 to 100: 1, 1:50 to 50:1, 1:20 to 20:1, 1:10 to 10:1, l:5to5:l, 1:3 to 2:1, 1:3 to 1:1, or 1:2.5.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Flumioxazin is 1:100 to 400: 1, 1:50 to 200:1, l:10to 100:1, 1:1 to 50:1, 5 :1 to 20:1, 5 :1 to 10:1, or 7:1.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Copper preparation is 1:400 to 100: 1, 1:200 to 50:1, 1:100 to 20:1, 1:50 to 10:1, 1 :30to5:l, 1:20 to 1:1, 1:20 to 1:5, or 1:12.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Metribuzin is 1:100 to 400: 1, 1:50 to 200:1, 1:20 to 100:1, l:10to50:l, 1 :5 to 20:1, 1:2 to 10:1, 1:1 to 5:1, or 3:1.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Clethodim is 1:100 to 400: 1, 1:50 to 200:1, 1:20 to 100:1, l:10to50:l, 1:1 to 20:1, 5:1 to 10:1, or8:l.

In some embodiments of the present disclosure, in the herbicidal mixture, the ratio of the application rate of Diquat or a salt thereof to that of Propaquizafop is 1 : 100 to 400: 1, 1 :50 to 200: 1, 1:20 to 100:1, l:10to50:l, 1:1 to 20:1, 5:1 to 10:1, or8:l.

In some embodiments of the present disclosure, the herbicidal mixture is synergistic, i.e., the herbicidal active ingredients are more effective when they are applied in combination than when they are applied separately. Synergy may be defined as "the interaction of two or more factors makes the effect of the combination greater than the expected effect based on the response to the individual factor applied separately" (Shaner, D.L., Ed. Herbicide Handbook, 10th ed. Lawrence: Weed Society of America, 2014). In some embodiments, the herbicidal mixture exhibits a synergistic effect as determined by Colby equation (Colby, S.R. Calculation of the synergistic and antagonistic response of herbicide combinations. Weeds 1967, 15, 20-22). The calculation of the synergistic effect through the Colby equation is described in detail in the Example section of the present disclosure.

In one embodiment of the present disclosure, the herbicidal mixture may comprise other active ingredients, such as other herbicides, insecticides, fungicides, bactericides, nematicides, molluscicides, growth regulators, biological agents, fertilizers, safeners, or mixtures thereof. However, for the avoidance of doubt, it should be understood that such other active ingredients are not necessary for the herbicidal mixture of the present invention to achieve the desired control of undesirable vegetation. In a further embodiment of the present disclosure, the premise of the presence of other active ingredients is not affecting the synergistic effect of the herbicidal mixture.

In one embodiment of the present disclosure, the herbicidal mixture does not comprise ingredients other than active ingredients, such as agricultural carriers.

In one embodiment of the present disclosure, the herbicidal mixture substantially consists of the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor. In one embodiment of the present disclosure, the herbicidal mixture substantially consists of the first herbicide Diquat or a salt thereof and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop.

In one embodiment of the present disclosure, the herbicidal mixture consists of the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor. In one embodiment of the present disclosure, the herbicidal mixture consists of the first herbicide Diquat or a salt thereof and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop.

The herbicidal mixture may be applied pre-emergence, post-emergence, or a combination thereof.

Second Aspect

In the second aspect, the present disclosure provides a herbicidal composition comprising the herbicidal mixture disclosed in the first aspect, and an agricultural carrier. It is found that, compared to the weed control expected to be observed on the basis of multiple individual herbicides, the herbicidal composition may provide a greater spectrum of weed control, or a reduced dosage of individual herbicide, or a synergistic weeding effect.

In one embodiment of the present disclosure, in the herbicidal composition, the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor are present in synergistic herbicidally effective amounts.

In one embodiment of the present disclosure, in the herbicidal composition, Diquat or a salt thereof as the first herbicide and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop are present in synergistic herbicidally effective amounts.

In one embodiment of the present disclosure, the herbicidal composition further comprises at least one surfactant.

In some embodiments of the present disclosure, the herbicidal composition is synergistic, i.e., the herbicidal active ingredients are more effective when they are applied in combination than when they are applied separately. Synergy may be defined as "the interaction of two or more factors makes the effect of the combination greater than the expected effect based on the response to the individual factor applied separately" (Shaner, D.L., Ed. Herbicide Handbook, 10th ed. Lawrence: Weed Society of America, 2014). In some embodiments, the herbicidal composition exhibits a synergistic effect as determined by Colby equation (Colby, S.R. Calculation of the synergistic and antagonistic response of herbicide combinations. Weeds 1967, 15, 20-22). The calculation of the synergistic effect through the Colby equation is described in detail in the Example section of the present disclosure.

In one embodiment of the present disclosure, the herbicidal composition may comprise other active ingredients, such as other herbicides, insecticides, fungicides, bactericides, nematicides, molluscicides, growth regulators, biological agents, fertilizers, safeners or mixtures thereof. However, for the avoidance of doubt, it should be understood that such other active ingredients are not necessary for the herbicidal composition of the present invention to achieve the desired control of undesirable vegetation. In a further embodiment of the present disclosure, the premise of the presence of other active ingredients is not affecting the synergistic effect of the herbicidal composition.

In one embodiment of the present disclosure, the active ingredients of the herbicidal composition substantially consist of the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor. In one embodiment of the present disclosure, the active ingredients of the herbicidal composition substantially consist of Diquat or a salt thereof as the first herbicide and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop.

In one embodiment of the present disclosure, the active ingredients of the herbicidal composition consist of the first herbicide selected from the group consisting of a photosynthesis inhibitor and the second herbicide selected from the group consisting of a glutamine synthetase inhibitor, a PPO inhibitor, a Photosystem II inhibitor, a root elongation inhibitor, a herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate, an Acetolactate Synthase inhibitor, a fatty acid, a VLCFA inhibitor, a multi-site herbicide, and an ACCase inhibitor. In one embodiment of the present disclosure, the active ingredients of the herbicidal composition consist of Diquat or a salt thereof as the first herbicide and the second herbicide selected from the group consisting of Glufosinate or a salt thereof, Saflufenacil, Diuron, Amitrole or a salt thereof, Asulam or a salt thereof, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, and Propaquizafop.

The agricultural carrier comprised in the herbicidal composition of the present disclosure may be a solid carrier, or a liquid carrier. Examples of suitable solid carriers include: mineral soils such as silica gel, silicate, talc, kaolin, activated clay (attaclay), limestone, lime, chalk, red basalt, loess, clay, dolomite, diatomite, calcium sulfate, magnesium sulfate, magnesium oxide, a mixture of ground materials of sodium carbonate and sodium bicarbonate, and sodium sulfate, ground synthetic materials; fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea; and plant-derived products such as grain flour, bark powder, wood powder and nut shell powder, cellulose powder, and other solid carriers. Examples of suitable liquid carriers include: water, alcohols such as methanol, cyclohexanol and decanol, ethylene glycol and propylene glycol, N,N-dimethylformamide, dimethyl sulfoxide, N-alkylpyrrolidone, aromatic hydrocarbons such as alkylbenzene and alkylnaphthalene, paraffin, olive oil, castor oil, linseed oil, tung oil, sesame oil, corn oil, peanut oil, cottonseed oil, soybean oil, rapeseed oil and coconut oil, aliphatic esters, ketones such as cyclohexanone, 2-heptanone, isophorone, 4-hydroxy-4-methyl-2-pentanone, etc.

In one embodiment of the present disclosure, the herbicidal composition of the present disclosure further comprises at least one surfactant. Examples of suitable surfactants comprised in the herbicidal composition of the present disclosure include, but are not limited to: nonionic, anionic, cationic and amphoteric types, such as alkoxylated fatty alcohol, ethoxylated polysorbate (e.g. Tween 20), ethoxylated castor oil, lignin sulfonate, fatty acid sulfonate (e.g. dodecyl sulfonate), phosphate ester such as phosphate ester of alcohol alkoxylate, phosphate ester of alkylphenol alkoxylate and phosphate ester of styrylphenol ethoxylate, sulfonated naphthalene and condensate of naphthalene derivative and formaldehyde, condensate of naphthalene or naphthalenesulfonic acid with phenol and formaldehyde, alkylarylsulphonate, ethoxylated alkylphenol and arylphenol, polyalkylene glycol, sorbitol ester, alkali metal (for example, sodium) lignosulfonate, tri styrylphenol ethoxylated phosphate ester, aliphatic alcohol ethoxylate, alkylphenol ethoxylate, ethylene oxide/propylene oxide block copolymer, graft copolymer, and polyvinyl alcohol-vinyl acetate copolymer. Other surfactants known in the art may be used as needed.

The herbicidal composition of the present disclosure may also comprise other ingredients, such as wetting agent, defoamer, adhesive, neutralizer, thickener, binder, chelating agent, stabilizer, buffer, or antifreezing agent, so as to increase the stability, density, viscosity, and so on of the composition.

Without departing from the scope of the present disclosure, the herbicidal composition of the present disclosure may also be applied together with one or more other herbicides to control a wider variety of undesirable vegetation. When being used in combination with other herbicides, the composition may be formulated with the other herbicides, tank mixed with the other herbicides, or applied sequentially with the other herbicides. Some of the other herbicides that may be used with the herbicidal composition of the present disclosure include, but are not limited to: chlorophenoxyacetic acid (4-CPA), chlorophenoxybutyric acid (4-CPB), chlorophenoxy propyl acid (4-CPP), 2,4-D, 2,4-D choline salt, 2,4-D ester and 2,4-D amine, 2,4-DB, 3,4-DA, 3,4-DB, 2,4-DEB, 2,4-DEP, 3,4-DP, 2,3,6-TBA, 2,4, 5-T, 2,4,5-TB, acetochlor, acifluorfen, aclonifen, acrolein, alachlor, allidochlor, alloxydim, allylalcohol, pentachloropentanonic acid (alorac), ametridione, ametryn, amibuzin, amicarbazone, amidosulfuron, aminocyclopyrachlor, aminopyralid, amiprofos-methyl, Amitrole or a salt thereof, ammonium sulfamate, anilofos, anisuron, Asulam or a salt thereof, atraton, atrazine, azafenidin, azimsulfuron, aziprotryne, barban, isopropyl m-chlorophenylcarbamate (BCPC), beflubutamid, benazolin, bencarbazone, benfuresate, bensulfuron-methyl, bensulide, benthiocarb, bentazon-sodium, benzadox, benzfendizone, benzipram, benzobicyclon, benzfendizone, benzofenap, benzofluor, benzoylprop, benzthiazuron, bialaphos, bicyclopyrone, bifenox, bilanafos, bispyribac-sodium, borax, bromacil, bromobonil, bromobutide, bromofenoxim, bromoxynil, brompyrazon, butachlor, butafenacil, butenachlor, buthidazole, buthiuron, butroxydim, buturon, butyrate, cacodylic acid, cafenstrole, calcium chlorate, calcium cyanamide, cambendichlor, carbAsulam or a salt thereof, carboxazole, chlorprocarb, carfentrazone-ethyl, CDEA, CEPC, chlomethoxyfen, chloramben, chloranocryl, chlorazifop, chlorazine, chlorbromuron, chlorbufam, chloreturon, chlorfenac, chlorfenprop, chlorflurazole, chlorflurenol, chloridazon, chlorimuron, chlornitrofen, chloropon, chlorotoluron, chloroxuron, chloroxynil, chlorsulfuron, chlorthal, chlorthiamid, cinidon-ethyl, cinmethylin, cinosulfuron, cisanilide, clethodim, cliodinate, clodinafop-propargyl, clofop, clomazone, clomeprop, cloprop, cloproxydim, clopyralid, cloransulam-methyl, CMA, copper sulfate, CPMF, CPPC, credazine, cresol, cumyluron, cyanatryn, cyanazine, cycloate, cyclopyrimorate, cyclosulfamuron, cycloxydim, cycluron, cyhalofop-butyl, cyperquat, cyprazine, cyprazole, cypromid, daimuron, dalapon, dazomet, delachlor, desmedipham, desmetryn, di-allate, dicamba, dichlobenil, dichloralurea, dichlormate, 2-(2,4-dichlorophenoxy)propionic acid (dichlorprop), dichlorprop-P, diclofop-methyl, diclosulam, diethamquat, diethatyl, difenopenten, difenoxuron, difenzoquat, diflufenzopyr, dimefuron, dimepiperate, dimethachlor, dimethametryn, dimexano, dimidazon, dinofenate, dinoprop, dinosam, dinoseb, dinoterb, diphenamid, dipropetryn, Diquat or a salt thereof, disul, diuron, DMPA, DNOC, DSMA, EBEP, eglinazine, endothal, epronaz, EPTC, erbon, esprocarb, ethbenzamide, ethametsulfuron, ethidimuron, ethiolate, etobenzamid, ethofumesate, ethoxyfen, ethoxysulfuron, etinofen, etnipromid, etobenzanid, EXD, fenAsulam or a salt thereof, fenoprop, fenoxaprop, fenoxaprop-P-ethyl, fenoxaprop-P-ethyl+isoxadifen-ethyl, fenoxasulfone, fenteracol, fenthiaprop, fentrazamide, fenuron, ferrous sulfate, flamprop, flamprop-M, flazasulfuron, florAsulam or a salt thereof, fluazifop, fluazifop-P -butyl, fluazolate, flucarbazone, flucetosulfuron, fluchloralin, flufenacet, flufenican, flufenpyr-ethyl, flumetsulam, flumezin, flumiclorac-pentyl, flumioxazin, flumipropyn, fluometuron, fluorodifen, fluoroglycofen, fluoromidine, fluoronitrofen, fluothiuron, flupoxam, flupropacil, flupropanate, flupyrsulfuron, fluridone, flurochloridone, fluroxypyr, fluroxypyr-meptyl, flurtamone, fluthiacet, fomesafen, foramsulfuron, fosamine, fumiclorac, furyloxyfen, Glufosinate or a salt thereof, Glufosinate or a salt thereof salts and esters, Glufosinate or a salt thereof-ammonium, Glufosinate or a salt thereof-P-ammonium, glyphosate, glyphosate salts and esters, halauxifen, halauxifen-methyl, halosafen, halosulfuron-methyl, haloxydine, haloxyfop-methyl, haloxyfop-P-methyl, hexachloroacetone, hexaflurate, hexazinone, imazamethabenz, imazamox, imazapic, imazapyr, imazaquin, imazosulfuron, imazethapyr, indanofan, indaziflam, iodobonil, iodomethane, iodosulfuron, iodosulfuron-ethyl-sodium, iofensulfuron, ioxynil, ipazine, ipfencarbazone, iprymidam, isocarbamid, isocil, isomethiozin, isonoruron, isopolinate, isopropalin, isoproturon, isouron, isoxachlortole, isoxaflutole, isoxapyrifop, karbutilate, ketospiradox, lactofen, lenacil, linuron, MAA, MAMA, ester and amine of MCPA, MCPA-thioethyl, MCPB, mecoprop, mecoprop-P, medinoterb, mefenacet, mefluidide, mesoprazine, mesosulfuron, mesotrione, metam, metamifop, metamitron, metazachlor, metazosulfuron, metflurazon, methabenzthiazuron, methalpropalin, methazole, methiobencarb, methiozolin, methiuron, methometon, metoprotryne, methyl bromide, methyl isothiocyanate, methyldymron, metobenzuron, metobromuron, metolachlor, metosulam, metoxuron, metribuzin, metsulfuron, metsulfuron-methyl, molinate, monalide, monisouron, monochloroacetic acid, monolinuron, monuron, morfamquat, MSMA, naproanilide, napropamide, naptalam, neburon, nicosulfuron, nipyraclofen, nitralin, nitrofen, nitrofluorfen, norflurazon, noruron, OCH, orbencarb, ortho-di chlorobenzene, orthosulfamuron, oxadiargyl, oxadiazon, oxapyrazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paraflufen-ethyl, parafluron, paraquat, pebulate, pelargonic acid, penoxsulam, pentachlorophenol, pentanochlor, pentoxazone, perfluidone, pethoxamid, phenisopham, phenmedipham, phenmedipham-ethyl, phenob enzuron, phenylmercury acetate, picloram, picolinafen, pinoxaden, piperophos, potassium arsenite, potassium azide, potassium cyanate, pretilachlor, primisulfuron-methyl, procyazine, prodiamine, profluazol, profluralin, profoxydim, proglinazine, prohexadione-calcium, prometon, prometryn, pronamide, propachlor, propanil, propaquizafop, propazine, propisochlor, propoxy carb azone, propyrisulfuron, propyzamide, prosulfalin, prosulfocarb, prosulfuron, proxan, prynachlor, pydanon, pyraclonil, pyraflufen-ethyl, pyrasulfotole, pyrazogyl, pyrazolynate, pyrazosulfuron-ethyl, pyrazoxyfen, pyribenzoxim, pyributicarb, pyriclor, pyridafol, pyridate, pyriftalid, pyriminobac, pyrimisulfan, pyrithiobac-sodium, pyroxasulfone, pyroxsulam, quinclorac, quinmerac, quinoclamine, quinonamid, quizalofop, quizalofop-P-ethyl, rhodethanil, rimsulfuron, saflufenacil, S-metolachlor, sebuthylazine, secbumeton, sethoxydim, siduron, simazine, simeton, simetryn, SMA, sodium arsenite, sodium azide, sodium chlorate, sulcotrione, sulfallate, sulfentrazone, sulfometuron, sulfosate, sulfosulfuron, sulfuric acid, sulgly capin, swep, SYN-523, trichloroacetic acid (TCA), tebutam, tebuthiuron, tefuryltrione, tembotrione, tepraloxydim, terbacil, terbucarb, terbuchlor, terbumeton, terbuthylazine, terbutryn, tetrafluoron, thiazafluron, thidiazimin, thidiazuron, thiencarbazone-methyl, thifensulfuron, thifensulfuron-methyl, thiobencarb, tiocarbazil, tioclorim, topramezone, tralkoxydim, triafamone, tri-allate, triasulfuron, triaziflam, tribenuron, tribenuron-methyl, tricamba, triclopyr choline salt, ester and salt of triclopyr, tridiphane, trietazine, trifloxysulfuron, trifluralin, triflusulfuron, trifop, trifopsime, trihydroxytriazine, trimeturon, tripropindan, tritac, tritosulfuron, vernolate, xylachlor, and salt, ester, optically active isomer, and mixture thereof.

The herbicidal composition of the present disclosure may be prepared or diluted during use. The herbicidal composition of the present disclosure may also be a concentrated composition, or a so-called "ready-to-use" composition, i.e., a composition for immediate use. Alternatively, the herbicidal composition of the present disclosure may be applied as a combined spray mixture composed of separate formulations of single active ingredients, for example, a "tank mixing" form.

The herbicidal composition of the present disclosure may be used or prepared in any conventional form, for example: a two-package form, or for example: wettable powder (WP), emulsifiable concentrate (EC), microemulsifiable concentrate (MEC), water-soluble powder (SP), water-soluble concentrate (SL), suspoemulsion (SE), oil dispersions (OD), concentrated emulsion (BW), for example: oil-in-water and water-in-oil emulsions, sprayable solution or emulsion, capsule suspension (CS), suspension concentrations (SC), dried powder (DP), oil miscible solution (OL), seed dressing products, granules in the form of microparticles (GR), spray granules, coated granules and absorbent granules, granules used for applying or spreading in soil, water-soluble granules (SG), water-dispersible granules (WDG), ultra-low volume (ULV) formulations, microcapsules or waxes, these individual formulation types are known in the art.

Such an herbicidal composition may be formulated by using agricultural carrier, surfactant, or other application-promoting auxiliaries conventionally used in formulation techniques and formulation processes known in the art.

In one embodiment of the present disclosure, the total amount of active ingredients in the herbicidal composition may be about 0.1-99 wt.%, about 0.1-95 wt.%, or about 0.1-90 wt.%, based on the total weight of the herbicidal composition. In another embodiment, the total amount of active ingredients in the herbicidal composition accounts for about 20-40 wt.% of the total weight of the composition. In another embodiment, the total amount of active ingredients in the composition accounts for about 0.1%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5% to about 90%, 93%, 95%, 98%, 99% of the total weight of the composition.

Aqueous forms for use may be prepared from emulsion concentrate, suspension, paste, wettable powder, or water-dispersible granule by adding water. In order to prepare emulsion, paste or oil dispersion, the components of the herbicidal composition may be taken by themselves or dissolved in an oil or solvent, and it may be homogenized in water by means of wetting agent, tackifier, dispersant or emulsifier. Alternatively, a concentrate may also be prepared, the concentrate comprises: active ingredients, wetting agent, tackifier, dispersant or emulsifier and, if necessary, a solvent or oil suitable for dilution with water.

The herbicidal composition may be applied pre-emergence, post- emergence, or a combination thereof.

In the present disclosure, unless otherwise indicated, all the specific descriptions made in the first aspect apply to the second aspect as all relevant descriptions have been copied here. For example, unless otherwise indicated, all the specific descriptions on the herbicidal mixture, the first herbicide, the second herbicide, the weight ratio of the first herbicide to the second herbicide, the application rates of the first herbicide and the second herbicide, the ratio of the application rates of the first herbicide to that of the second herbicide, etc., in the first aspect apply to the second aspect as all relevant specific descriptions have been copied here.

Third Aspect

In the third aspect, the present disclosure provides a method for controlling undesirable vegetation, which includes applying a herbicidally effective amount of the herbicidal mixture disclosed in the first aspect or the herbicidal composition disclosed in the second aspect of the present disclosure to the undesirable vegetation or its locus.

In one embodiment of the present disclosure, the undesirable vegetation is controlled in crops, e.g., potatoes, soybean, corn, cereals, cotton, OSR, Field Pea, Faba/Broad Bean, Chickpea, Lentil, or Lupin, orchards, TNV, sugar cane, or non-crop area.

In one embodiment of the present disclosure, the undesirable vegetation is selected from the group consisting of: Fleabane (Conyza bonariensis), Indian hedge mustard (Sisymbrium orientale), Sowthistle/ Milk thistle (Sonchus oleraceus), Prickly lettuce (Lactuca serriola), Amaranthus, Barley Grass, Barnyard Grass, Capeweed, Cobbler s ’ , and the combination thereof.

In one embodiment of the present disclosure, the herbicidal mixture or the herbicidal composition may be applied pre- emergence.

In one embodiment of the present disclosure, the herbicidal mixture or the herbicidal composition may be applied post- emergence.

In one embodiment of the present disclosure, the following undesirable vegetation may also be expected to be controlled: Medicago sativa, Amsinckia spp., Arctotheca calendula, Sinapis arvensis, Stellaria media, Buglossoides arvensis, Agropyron repens, Mentha arvensis, Crassula L., Cirsium arvense, Calystegia sepium, Tripleurospermum maritimum, Convolvulus arvensis, Aethusa cynapium, Galinsoga parviflora, Lamium amplexicaule, Sisymbrium officinale, Lythrum hyssopifolia, Sisymbrium orientale, Lolium multiflorum, Malva parviflora, Cerastium glomeratum, Matthiola longipetala, Echium plantagineum, Adonis microcarpa, Matricaria discoidea, Euphorbia pulcherrima, Lactuca serriola, Lamium purpureum, Papaver hybridum, Capsella bursa-pastoris, Chondrilla juncea, Rumex acetosella, Veronica hederifolia, Urtica urens, Juncus bufonius, Rapistrum rugosum, Raphanus raphanistrum, Brassica tournefo rtii, Polygonum aviculare, Mercurialis annua, Datura ferox, Neslia paniculata, Echinochloa crusgalli, sugarbeet, Fallopia convolvulus, Alopecurus myosuroides, Trianthema portulacastrum, Hirschfeldia incana, Tribulus terrestris, Abutilon theophrasti, Hypochaerisradicata, Galium aparine, Anthusa arvensis, Boragio officinales, Cotula australis, Senecio vulgaris, Galeopsis tetrahit, Urtica dioica, Spergula arvensis, Veronica filiformis, Verbesina encelioides, Eleusine indica, Rumex spp., Emex australis, Atriplex prostrata, Sherardia arvensis, Viola arvensis, Thlaspi arvense, Holcus lanatus, Fumaria L., Fumaria officinalis, Geranium spp., Geranium dissectum, Bromus diandrus, Plantago major, Digitaria ciliaris, Conringia orientalis, Heliotropium spp., Galeopsis spp., Marrubium vulgare, Sisymbrium orientals, Coronopusdidy mus, Matricaria spp., Matricaria recutita, Matricaria inodor a, Calandrinia ciliata, Brassica juncea, Urtica fissa E. Pritz., Urtica spp., Solanum nigrum, Persicaria lapathifolia, Sonchus arvensis, Veronica persica, Chenopodium spp., Chenopodium album, Amaranthus powellii, Galeopsis intermedia, Persicaria maculosa, Amaranthus retroflexus, Anagallis arvensis, Urtica incisa, Sonchus oleraceus, Emex australis, Atriplex patula, Stachys arvensis, Erodium cicutarium, summer grass, Euphorbia helioscopia, Juncus bufonius, Polygonum convolvulus, Polygonum spp., Viola tricolor, Poa Annua, Avena fatua, Brassica napus, and Amsinckia calycina.

The herbicidal mixture or the herbicidal composition of the present disclosure may be applied to undesirable vegetation or its locus by using conventional ground or aerial dusters, sprayers, and pellet applicators, and by other conventional methods known to those skilled in the art.

In one embodiment, the method for controlling undesirable vegetation of the present disclosure achieves a synergistic weeding effect. In a further embodiment, the method of controlling undesirable vegetation of the present disclosure achieves a synergistic effect on Fleabane (Conyza bonariensis), Indian hedge mustard (Sisymbrium orientals), Sowthistle/ Milk thistle (Sonchus oleraceus), Prickly lettuce (Lactuca serriola), Amaranthus, Barley Grass, Barnyard Grass, Capeweed, Cobbler s ’ , or the combination thereof.

In this disclosure, unless otherwise specified, the above descriptions on herbicidal mixture in the first aspect and herbicidal composition disclosed in the second aspect are applicable to the descriptions about the method for controlling undesirable vegetation in the third aspect, as if all the relevant descriptions are repeated herein. Similarly, where appropriate, the descriptions in this section regarding the method for controlling undesirable vegetation in the third aspect may also be applied to the herbicidal mixture in the first aspect and the herbicidal composition in the second aspect, as if all the relevant descriptions are repeated in the corresponding part above. For example, unless otherwise indicated, all the specific descriptions on the herbicidal mixture, the first herbicide, the second herbicide, the weight ratio of the first herbicide to the second herbicide, the application rates of the first herbicide and the second herbicide, the ratio of the application rate of the first herbicide to that of the second herbicide, etc., in the first aspect apply to the third aspect as all relevant specific descriptions have been copied here. For another example, similar to the description of the herbicidal mixture in the first aspect and the herbicidal composition in the second part of the present disclosure, in one embodiment of the method for controlling undesirable vegetation of the present disclosure, the first herbicide and the second herbicide are applied in combination or sequentially. In one example, the first herbicide and the second herbicide are separately prepared, and each of them is applied as it is, or diluted to a predetermined concentration for application. In another example, the first herbicide and the second herbicide are separately prepared, and after being diluted to a predetermined concentration if necessary, they are mixed and then applied. In another example, the first herbicide and the second herbicide are formulated together, and then applied as it is, or diluted to a predetermined concentration for application.

Fourth Aspect

In the fourth aspect, the present disclosure provides an use of the herbicidal mixture disclosed in the first aspect or the herbicidal composition disclosed in the second aspect for controlling undesired vegetation.

In this disclosure, unless otherwise specified, the above descriptions on herbicidal mixture in the first aspect, herbicidal composition disclosed in the second aspect and the method for controlling undesirable vegetation in the third aspect are applicable to the use in the fourth aspect, as if all the relevant descriptions are repeated herein. For example, unless otherwise indicated, all the specific descriptions on the herbicidal mixture, the first herbicide, the second herbicide, the weight ratio of the first herbicide to the second herbicide, the application rates of the first herbicide and the second herbicide, the ratio of the application rate of the first herbicide to that of the second herbicide, etc., in the first aspect apply to the fourth aspect as all relevant specific descriptions have been copied here.

Fifth Aspect

In the fifth aspect, the present disclosure provides a kit comprising the herbicidal mixture disclosed in the first aspect or the herbicidal composition disclosed in the second aspect of the present disclosure. In this disclosure, unless otherwise specified, the above descriptions on herbicidal mixture in the first aspect and herbicidal composition disclosed in the second aspect are applicable to the kit in the fifth aspect, as if all the relevant descriptions are repeated herein. For example, unless otherwise indicated, all the specific descriptions on the herbicidal mixture, the first herbicide, the second herbicide, the weight ratio of the first herbicide to the second herbicide, the application rates of the first herbicide and the second herbicide, the ratio of the application rate of the first herbicide to that of the second herbicide, etc., in the first aspect apply to the fifth aspect as all relevant specific descriptions have been copied here.

In addition to the active ingredients (i.e., the first and second herbicides) comprised in the herbicidal mixture or the herbicidal composition described herein, the kit of the present disclosure may also comprise one or more other active ingredients and/or inactive ingredients, the active ingredients and the inactive ingredients may be provided in the herbicidal mixture or provided independently.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the first herbicide and the second herbicide, and they are contained in the same container and optionally combined with a carrier.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicidal mixture of the present disclosure, which is contained in a container.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicidal mixture of the present disclosure, which is optionally combined with a carrier.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicidal composition of the present disclosure, which is contained in a container.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the first herbicide and the second herbicide, and each of them is contained in a separate container and optionally combined with a carrier.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicidal mixture of the present disclosure, and the first herbicide and the second herbicide are each contained in a separate container and optionally combined with a carrier.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicidal composition of the present disclosure, and the first herbicide and the second herbicide and the agricultural carrier are each contained in a separate container.

In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicidal composition of the present disclosure, and the first herbicide and the second herbicide are each contained in a separate container, and the agricultural carrier is contained in a container.

In one embodiment of the present disclosure, the kit of the present disclosure also comprises instructions on how to apply the first herbicide and the second herbicide, the herbicidal mixture of the present disclosure, or the herbicidal composition of the present disclosure to the undesirable vegetation or its locus.

It should be recognized that, one or more features, aspects, or embodiments of the present disclosure may be combined with one or more other features, aspects, or embodiments of the present disclosure.

It should be recognized that, all embodiments of the present disclosure, including those specifically described for different aspects of the present disclosure, may be combined with any other embodiments of the present disclosure as appropriate.

Sixth Aspect

In the sixth aspect, the present disclosure provides a method for desiccating a crop, which includes applying a herbicidally effective amount of the herbicidal mixture disclosed in the first aspect or the herbicidal composition disclosed in the second aspect of the present disclosure to the crop.

In one embodiment of the present disclosure, the crop is selected from the group consisting of beans (e.g. white beans or red kidney beans), soybean, canola, chickpeas, flax, legumes (e.g. alfalfa, birdsfoot trefoil, red clover and white clover), lentils, mustard, oats, field peas, dry peas, potatoes, lupins (e.g. sweet white lupins), sunflower, for example, canola, potatoes, field peas, or lentils.

The herbicidal mixture or the herbicidal composition of the present disclosure may be applied to the crop by using conventional ground or aerial dusters, sprayers, and pellet applicators, and by other conventional methods known to those skilled in the art.

In one embodiment, the method for desiccating a crop of the present disclosure achieves a synergistic desiccating effect.

In this disclosure, unless otherwise specified, the above descriptions on herbicidal mixture in the first aspect and herbicidal composition disclosed in the second aspect are applicable to the descriptions about the method for desiccating a crop in the sixth aspect, as if all the relevant descriptions are repeated herein. Similarly, where appropriate, the descriptions in this section regarding the method of desiccating a crop in the sixth aspect may also be applied to the herbicidal mixture in the first aspect and the herbicidal composition in the second aspect, as if all the relevant descriptions are repeated in the corresponding part above. For example, unless otherwise indicated, all the specific descriptions on the herbicidal mixture, the first herbicide, the second herbicide, the weight ratio of the first herbicide to the second herbicide, the application rates of the first herbicide and the second herbicide, the ratio of the application rate of the first herbicide to that of the second herbicide, etc., in the first aspect apply to the sixth aspect as all relevant specific descriptions have been copied here. For another example, similar to the description of the herbicidal mixture in the first aspect and the herbicidal composition in the second part of the present disclosure, in one embodiment of the method for desiccating a crop of the present disclosure, the first herbicide and the second herbicide are applied in combination or sequentially. In one example, the first herbicide and the second herbicide are separately prepared, and each of them is applied as it is, or diluted to a predetermined concentration for application. In another example, the first herbicide and the second herbicide are separately prepared, and after being diluted to a predetermined concentration, if necessary, they are mixed and then applied. In another example, the first herbicide and the second herbicide are formulated together, and then applied as it is, or diluted to a predetermined concentration for application.

Seventh Aspect

In the seventh aspect, the present disclosure provides the use of the herbicidal mixture disclosed in the first aspect or the herbicidal composition disclosed in the second aspect for desiccating a crop.

In this disclosure, unless otherwise specified, the above descriptions on herbicidal mixture in the first aspect, herbicidal composition disclosed in the second aspect and the method for controlling undesirable vegetation in the third aspect are applicable to the use in the seventh aspect, as if all the relevant descriptions are repeated herein. For example, unless otherwise indicated, all the specific descriptions on the herbicidal mixture, the first herbicide, the second herbicide, the weight ratio of the first herbicide to the second herbicide, the application rates of the first herbicide and the second herbicide, the ratio of the application rate of the first herbicide to that of the second herbicide, etc., in the first aspect apply to the seventh aspect as all relevant specific descriptions have been copied here.

EXAMPLES

The following examples do not limit the present disclosure, but merely illustrate how the present disclosure is implemented.

Referring to an article of Colby, S.R. i.e., Calculation of the synergistic and antagonistic response of herbicide combinations. Weeds 1967, 15, pp.20-22 (which is incorporated herein in its entirety by reference), the theoretical value E0 of a given mixture of two active ingredients may be predicted according to the following equation, then evaluating whether there is a synergy.

E0=X+Y-(X*YM00) wherein:

E0 is the theoretical fresh weight survival rate for the mixture of the first herbicide and the second herbicide;

X is the measured fresh weight survival rate for the first herbicide used alone at the same dosage as that in the mixture; and

Y is the measured fresh weight survival rate for the second herbicide used alone at the same dosage as that in the mixture.

There is synergy whenever the value of E-EO is greater than 0, wherein E is the measured fresh weight survival rate for the mixture of the first herbicide and the second herbicide.

Field trial 1

Three tank mixes were prepared as described below:

1. Diquat at 300 g a.i. per hectare (from commercial product Armory 240EC), was mix in a tank with agitation water and Agral 90 as a wetting agent (0.1% v/v).

2. Saflufenacil at 36 g a.i. per hectare as SL solution was mix with Addit as an adjuvant (0.5% v/v). 3. A tank mix of Diquat and Saflufenacil :

Diquat at 300 g a.i. per hectare (commercial product Armory 240EC)

Saflufenacil at 36 g a.i. per hectare as SL solution

Addit as an adjuvant (0.5% v/v).

The above tank mixtures were applied to the field containing peas and CHEAL (Chenopodium album) according to the directions on the label of Armory 240EC. Specifically, we sprayed 1.477 L/ha (1250 mL of treatment 1 + 227 mL of treatment 2) of the tank mix for treatment 3, 1250 mL/ha of treatment 1, and 227 mL/ha of treatment 2. Table 1 shows the grams of active ingredient per hectare (a.i./ha) for each treatment. We measured CHEAL dry down two days after application, comparing it to an untreated field, and recorded the amounts and results for each treatment in Table 1.

Table 1 :

Colby’s Equation:

We wanted to test whether mixing Diquat and Saflufencil would produce a greater effect than expected. To do this, we used Colby's equation. If the observed value of the mixture was greater than the expected value (i.e., E>E0), we could prove that the two chemicals had a synergistic effect when combined.

The efficacy of Diquat on CHEAL dry down was 55%, while the efficacy of Saflufenacil on CHEAL was 0%. When we mixed Diquat and Saflufenacil in a tank, we observed an efficacy of 92%. The expected (E ) of the mix calculated to be 55%. Table 2:

The results clearly demonstrate that when Diquat and Saflufenacil are mixed in a tank (treatment 3, table 1), they provide synergistic control over broad leaf weeds (such as CHEAL and other), as compared to using either active ingredient alone (treatments 1 or 2, table 1), without increasing the phytotoxicity towards peas.

Field trial 2

Three tank mixes were prepared as described in treatments 1, 2, and 3, and then applied the tank mix to the field according to the directions on the label of Armory 240EC, with the objective of desiccating canola crop prior to harvesting. Specifically, we sprayed 1.477 L/ha (1250 mL of treatment 1 + 227 mL of treatment 2) of the tank mix for treatment 3, 1250 mL/ha of treatment 1, and 227 mL/ha of treatment 2. Table 3 shows the grams of active ingredient per hectare (a.i./ha) for each treatment. We measured % of dry canola (crop desiccation) three days after application, comparing it to an untreated field, and recorded the amounts and results for each treatment in Table 3.

Colby’s Equation: We wanted to test whether mixing Diquat and Saflufencil would produce a greater effect than expected. To do this, we used Colby's equation. If the observed value of the mixture was greater than the expected value (i.e., E>E0), we could prove that the two chemicals had a synergistic effect when combined.

We utilized an herbicide harvest aid kit to facilitate drying of the field through application. The parameter we measured was the percentage of dry field. After applying Diquat, the field was 24% dry compared to the control, while the crop was 40% dry after applying Saflufenacil. When we mixed Diquat and Saflufenacil in a tank, the entire crop in the field was 100% dry. Additionally, the expected efficacy (E) of the mix was calculated to be 54.5%.

Table 4:

Our results clearly demonstrate that when Diquat and Saflufenacil are mixed in a tank (treatment 3, table 3), they provide synergistic desiccation of canola crop, as compared to using either Al alone (treatments 1 or 2, table 3).

Field trial 3

We prepared three tank mixes as described in treatments 1, 4, and 5,

4. Glufosinate ammonium at 300 g a.i. per hectare as SL solution was mix in a tank.

5. A tank mix of 2 a.i. and adjuvant:

Diquat at 300 g a.i. per hectare (commercial product Armory 240EC) Glufosinate ammonium at 300 g a.i. per hectare as SL solution.

Agral 90 as a wetting agent (0.1% v/v). Treatments were then applied the tank mix to the field containing peas and CHEAL (Chenopodium album) according to the directions on the label of Armory 240EC. Specifically, we sprayed 2.106 L/ha (1250 mL of treatment 1 + 856 mL of treatment 4) of the tank mix for treatment 5, 1250 mL/ha of treatment 1, and 856 mL/ha of treatment 2. Table 5 shows the grams of active ingredient per hectare (a.i./ha) for each treatment. We measured CHEAL dry down two days after application, comparing it to an untreated field, and recorded the amounts and results for each treatment in Table 5.

Table 5:

Colby’s Equation:

We wanted to test whether mixing Diquat and Glufosinate ammonium would produce a greater effect than expected. To do this, we used Colby's equation. If the observed value of the mixture was greater than the expected value (i.e., E>E0), we could prove that the two chemicals had a synergistic effect when combined.

In trial 3, we measured the efficacy of Diquat on CHEAL dry down to be 55%, while the efficacy of Glufosinate ammonium on CHEAL was 66%. When we mixed Diquat and Glufosinate ammonium in a tank, we observed an efficacy of 97%. The expected (E0) of the mix calculated to be 84.7%.

Table 6:

Our results clearly demonstrate that when Diquat and Glufosinate ammonium are mixed in a tank (treatment 5, table 5), they provide synergistic control over hard-to-kill weeds, as compared to using either Al alone (treatments 1 or 4, table 5).

Claims

2. The herbicidal mixture of claim 1, wherein the photosynthesis inhibitor is selected from the group consisting of Diquat, Paraquat, mixtures or salts thereof.

3. The herbicidal mixture of claim 2, wherein the photosynthesis inhibitor is Diquat or a salt thereof.

4. The herbicidal mixture of any one of claims 1 to 3, wherein Diquat or a salt thereof is Diquat dichloride or Diquat dibromide.

5. The herbicidal mixture of any one of claims 1 to 4, wherein the glutamine synthetase inhibitor is selected from the group consisting of Glufosinate, bilanafos or phosphinothricin or a salt thereof.

6. The herbicidal mixture of claim 5, wherein the glutamine synthetase inhibitor is selected from the group consisting of Glufosinate or a salt thereof.

7. The herbicidal mixture of any one of claims 1 to 6, wherein the PPO inhibitor is selected from the group consisting of Saflufenacil, Sulfentrazone, Carfentrazone, Trifludimoxazin, Flumioxazin, and Flumipropyn.

8. The herbicidal mixture of claim 7, wherein the PPO inhibitor is selected from the group consisting of Saflufenacil and Flumioxazin.

9. The herbicidal mixture of any one of claims 1 to 8, wherein the Photosystem II inhibitor is selected from the group consisting of Diuron, Chlorotoluron, Linuron, Isoproturon, Fluometuron, metribuzine, Metamitron, Atrazine, and Simazine.

10. The herbicidal mixture of claim 9, wherein the Photosystem II inhibitor is selected from the group consisting of Diuron and metribuzine.

11. The herbicidal mixture of any one of claims 1 to 10, wherein the root elongation inhibitor is Amitrol e or a salt thereof.

12. The herbicidal mixture of any one of claims 1 to 11, wherein the herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate is selected from the group consisting of Asulam, Carbetamide and salts thereof.

13. The herbicidal mixture of claim 12, wherein the herbicide inhibiting enzyme activity blocking the conversion of 4-aminobenzoic acid plus 7,8-dihydropteroate derivatives to 7,8-dihydropteroate is Asulam or a salt thereof.

14. The herbicidal mixture of any one of claims 1 to 13, wherein the Acetolactate Synthase inhibitor is selected from the group consisting of Imazamox, Imazapic, Imazaquin, Imazapyr, Imazethapyr, and Imazosulfuron.

15. The herbicidal mixture of claim 14, wherein the Acetolactate Synthase inhibitor is Imazamox.

16. The herbicidal mixture of any one of claims 1 to 15, wherein the fatty acid is Pelargonic acid.

17. The herbicidal mixture of any one of claims 1 to 16, wherein the VLCFA inhibitor is selected from the group consisting of S-metolachlor, Metolachlor, Pyroxasulfone, Flufenacet, Metazachlor, and Dimethenamid.

18. The herbicidal mixture of claim 14, wherein the VLCFA inhibitor is S-metolachlor.

19. The herbicidal mixture of any one of claims 1 to 18, wherein the multi-site herbicide is a copper preparation.

20. The herbicidal mixture of any one of claims 1 to 19, wherein the ACCase inhibitor is selected from the group consisting of Clethodim, Sethoxydim, Propaquizafop, and quizalofop.

21. The herbicidal mixture of claim 14, wherein the ACCase inhibitor is selected from the group consisting of Clethodim and Propaquizafop.

22. The herbicidal mixture of claim 1, wherein the photosynthesis inhibitor is Diquat or a salt thereof, and the second herbicide is selected from the group consisting of Glufosinate, Saflufenacil, Diuron, Amitrole, Asulam, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, Propaquizafop, and salts or esters thereof.

23. The herbicidal mixture of any one of claims 1 to 22, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 :400 to 400: 1.

24. The herbicidal mixture of claim 23, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 :200 to 200: 1.

25. The herbicidal mixture of claim 23, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 : 100 to 100: 1.

26. The herbicidal mixture of claim 23, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 :50 to 50: 1.

27. The herbicidal mixture of claim 23, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 :20 to 20: 1.

28. The herbicidal mixture of claim 23, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 : 10 to 10: 1.

29. The herbicidal mixture of claim 23, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 :5 to 5: 1.

30. The herbicidal mixture of claim 23, wherein the weight ratio of the photosynthesis inhibitor to the second herbicide is 1 : 1.

31. The herbicidal mixture of any one of claims 1 to 30 wherein the photosynthesis inhibitor and the second herbicide are applied jointly or in a succession.

32. The herbicidal mixture of any one of claims 1 to 31, wherein the total application rate of the photosynthesis inhibitor and second herbicide are 1-20000 g ai/ha.

33. The herbicidal mixture of any one of claims 1 to 32, wherein the herbicidal mixture is synergistic.

34. The herbicidal mixture of any one of claims 1 to 33, wherein the herbicidal mixture consists of the photosynthesis inhibitor and the second herbicide.

35. The herbicidal mixture of claim 34, wherein the herbicidal mixture consists of the photosynthesis inhibitor Diquat or a salt thereof and the second herbicide selected from the group consisting of Glufosinate, Saflufenacil, Diuron, Amitrole, Asulam, Imazamox, Pelargonic acid, S-metolachlor, Flumioxazin, a Copper preparation, Metribuzin, Clethodim, Propaquizafop, and salts or esters thereof.

36. A herbicidal composition comprising the herbicidal mixture of any one of claims 1 to 35, and an agriculturally acceptable carrier.

37. The herbicidal composition of claim 36, further comprising at least one surfactant.

38. A method of controlling undesired vegetation comprising applying to the undesirable vegetation or its locus a herbicidally effective amount of the herbicidal mixture of any one of claims 1 to 35 or the herbicidal composition of any one of claims 36-37.

39. The method of claim 38 wherein the undesired vegetation is controlled in a crop selected from the group consisting of Potatoes, soybean, corn, cereals, cotton, OSR, Field Pea, Faba/Broad Bean, Chickpea, Lentil, and Lupin.

40. The method of claim 38 or 39 wherein the undesired vegetation is selected from the group consisting of Fleabane (Conyza bonariensis), Indian hedge mustard (Sisymbrium orientale), Sowthistle/ Milk thistle (Sonchus oleraceus), Prickly lettuce (Lactuca serriola), Amaranthus, Barley Grass, Barnyard Grass, Capeweed, Cobbler s ’ , and the combination thereof

41. Use of the herbicidal mixture of any one of claims 1 to 35 or the herbicidal composition of any one of claims 36-37 for controlling undesired vegetation.

42. A kit comprising the herbicidal mixture of any one of claims 1 to 35 or the herbicidal composition of any one of claims 36-37.

43. A method of desiccating a crop comprising applying to the crop an effective amount of the herbicidal mixture of any one of claims 1 to 35 or the herbicidal composition of any one of claims 36-37.

44. The method of claim 43 wherein the crop selected from the group consisting of canola, potatoes, field peas, and lentils.

45. Use of the herbicidal mixture of any one of claims 1 to 35 or the herbicidal composition of any one of claims 36-37 for desiccating a crop.