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UY32174A - Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones - Google Patents

Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones

Info

Publication number
UY32174A
UY32174A UY0001032174A UY32174A UY32174A UY 32174 A UY32174 A UY 32174A UY 0001032174 A UY0001032174 A UY 0001032174A UY 32174 A UY32174 A UY 32174A UY 32174 A UY32174 A UY 32174A
Authority
UY
Uruguay
Prior art keywords
heterocicles
applications
pharmaceutical compositions
compositions containing
preparation procedures
Prior art date
Application number
UY0001032174A
Other languages
English (en)
Inventor
Barvian Kevin
Gregory Steven Basarab
Madhusudhan Ready Gowravaram
Sheila Irene Hauck
Zhou Fei
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY32174A publication Critical patent/UY32174A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a compuestos de Fórmula (I): Formula (I) a sales faramcéuticamente aceptables del mismo, a métodos para usarlos para tratar infecciones bacterianas y a métodos para su preparación.
UY0001032174A 2008-10-14 2009-10-13 Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones UY32174A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10518908P 2008-10-14 2008-10-14

Publications (1)

Publication Number Publication Date
UY32174A true UY32174A (es) 2010-05-31

Family

ID=41668347

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032174A UY32174A (es) 2008-10-14 2009-10-13 Nuevos heterociclos sustituidos, composiciones farmaceuticas conteniendolos, procedimientos de preparacion y aplicaciones

Country Status (24)

Country Link
US (1) US8658641B2 (es)
EP (1) EP2350077B1 (es)
JP (2) JP5749169B2 (es)
KR (1) KR101676886B1 (es)
CN (2) CN102245605B (es)
AR (1) AR073862A1 (es)
AU (1) AU2009305203B2 (es)
BR (1) BRPI0920180B1 (es)
CA (1) CA2736335C (es)
CL (1) CL2011000838A1 (es)
CO (1) CO6382126A2 (es)
CR (1) CR20110195A (es)
CU (1) CU20110083A7 (es)
DO (1) DOP2011000102A (es)
EA (1) EA201100613A1 (es)
EC (1) ECSP11010980A (es)
ES (1) ES2565611T3 (es)
HK (2) HK1160127A1 (es)
IL (1) IL211728A0 (es)
MX (1) MX2011003598A (es)
TW (1) TW201020258A (es)
UY (1) UY32174A (es)
WO (1) WO2010043893A1 (es)
ZA (1) ZA201103533B (es)

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ES2926662T3 (es) 2012-08-21 2022-10-27 Janssen Pharmaceutica Nv Anticuerpos contra haptenos de risperidona y uso de los mismos
PT2888286T (pt) 2012-08-21 2018-05-09 Janssen Pharmaceutica Nv Anticorpos para haptenos de quetiapina e sua utilização
US9394354B2 (en) 2012-08-21 2016-07-19 Janssen Pharmaceutica Nv Haptens of paliperidone
ES2807902T3 (es) 2012-08-21 2021-02-24 Janssen Pharmaceutica Nv Anticuerpos para olanzapina y uso de los mismos
JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
EP2888277A4 (en) 2012-08-21 2016-05-18 Ortho Clinical Diagnostics Inc ANTIBODIES AGAINST PALIPERIDONE AND USE THEREOF
JP6242893B2 (ja) 2012-08-21 2017-12-06 ヤンセン ファーマシューティカ エヌ．ベー． クエチアピンに対する抗体及びその使用
PL2888269T3 (pl) 2012-08-21 2019-06-28 Janssen Pharmaceutica Nv Hapteny olanzapiny
EP2888593B1 (en) 2012-08-21 2018-09-19 Janssen Pharmaceutica NV Antibodies to risperidone and use thereof
ES2652641T3 (es) 2012-08-21 2018-02-05 Janssen Pharmaceutica Nv Haptenos de aripiprazol y su uso en inmunoensayos
JP6131415B2 (ja) 2012-08-21 2017-05-24 ヤンセン ファーマシューティカ エヌ．ベー． イムノアッセイに使用するためのクエチアピンのハプテン
JP6389177B2 (ja) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ．ベー． オランザピンハプテンに対する抗体及びその使用
CN104755479B (zh) 2012-08-21 2016-11-09 詹森药业有限公司 利培酮和帕潘立酮的半抗原
EP2888285B1 (en) 2012-08-21 2024-04-17 Janssen Pharmaceutica NV Antibodies to aripiprazole haptens and use thereof
CN102911188B (zh) * 2012-08-22 2015-01-07 中国科学院南海海洋研究所 含硫双吲哚二酮哌嗪类化合物及其在制备抗肿瘤药物中的应用
US8889671B2 (en) 2013-01-23 2014-11-18 Astrazeneca Ab Compounds and methods for treating bacterial infections
MX365261B (es) 2014-05-29 2019-05-27 Entasis Therapeutics Ltd Compuestos heteroaromaticos espirociclicos, fusionados para el tratamiento de infecciones bacterianas.
US10139729B2 (en) * 2014-08-25 2018-11-27 Nissan Chemical Industries, Ltd. Coating composition for pattern reversal on soc pattern
HUE066864T2 (hu) 2014-11-06 2024-09-28 Bial R&D Invest S A Helyettesített pirazolo(1,5-a)pirimidinek és alkalmazásuk orvosi rendellenességek kezelésében
AU2015342883B2 (en) 2014-11-06 2020-07-02 Bial - R&D Investments, S.A. Substituted pyrrolo(1,2-a)pyrimidines and their use in the treatment of medical disorders
WO2016073889A1 (en) 2014-11-06 2016-05-12 Lysosomal Therapeutics Inc. Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders
TW201629026A (zh) 2015-02-02 2016-08-16 佛瑪治療公司 作為ｈｄａｃ抑制劑的３－烷基雙環［４，５，０］異羥肟酸
WO2016126726A1 (en) 2015-02-02 2016-08-11 Forma Therapeutics, Inc. Bicyclic [4,6,0] hydroxamic acids as hdac6 inhibitors
US9637453B2 (en) 2015-04-17 2017-05-02 Forma Therapeutics, Inc. 3-spirocyclic-6-hydroxamic acid tetralins as HDAC inhibitors
WO2017024455A1 (zh) * 2015-08-07 2017-02-16 苏州大学张家港工业技术研究院 一种螺环羟吲哚咪唑啉并氧氮杂卓化合物及其合成方法
CN105152962B (zh) * 2015-09-30 2017-06-16 淄博亿丰高分子材料科技股份有限公司 N‑异丙基羟胺的制备方法
CN108368180B (zh) 2015-12-17 2022-07-26 詹森药业有限公司 喹硫平的抗体及其用途
US10444250B2 (en) 2015-12-17 2019-10-15 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof
EP3440083A4 (en) 2016-04-06 2019-09-18 Lysosomal Therapeutics Inc. IMIDAZO [1,5-A] PYRIMIDINYL-CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDER
CA3020310A1 (en) 2016-04-06 2017-10-12 Lysosomal Therapeutics Inc. Pyrrolo[1,2-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders
BR112018070586A8 (pt) 2016-04-06 2023-03-14 Lysosomal Therapeutics Inc Compostos de pirazol[1,5-a]pirimidinil carboxamida e seu uso no tratamento de distúrbios médicos
MX2018013529A (es) 2016-05-05 2019-07-04 Lysosomal Therapeutics Inc Imidazo[1,2-b]piridazinas sustituidas, imidazo[1,5-b]piridazinas sustituidas, compuestos relacionados y su uso en el tratamiento de trastornos médicos.
WO2017192931A1 (en) 2016-05-05 2017-11-09 Lysosomal Therapeutics Inc. SUBSTITUTED IMDAZO[1,2-α]PYRIDINES, SUBSTITUTED IMIDAZO[1,2-α]PYRAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
WO2017218950A1 (en) 2016-06-17 2017-12-21 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as hdac inhibitors
CN109111465B (zh) * 2017-06-22 2021-01-12 中国科学院上海药物研究所 噻唑烷酮螺嘧啶三酮类化合物及制备方法和用途
CN107827887B (zh) * 2017-11-21 2019-01-08 上海博栋化学科技有限公司 具有抗细菌活性的三氮唑甲酯链接螺环类化合物及其制备方法和应用
US11905286B2 (en) 2018-08-09 2024-02-20 Antabio Sas Diazabicyclooctanones as inhibitors of serine beta-lactamases
CN111925370B (zh) * 2020-09-01 2023-07-21 湖北科苑生物药业有限公司 一种吡嗪并吡唑并萘啶类化合物及其制备方法与应用

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US7208490B2 (en) * 2002-10-07 2007-04-24 Pharmacia & Upjohn Company Llc Tricyclic tetrahydroquinoline antibacterial agents
WO2005016929A1 (en) * 2003-08-15 2005-02-24 Astrazeneca Ab Fused heterocylcles as inhibitors of glutamate racemase (muri)
EP1888597A2 (en) * 2005-05-09 2008-02-20 Warner-Lambert Company LLC Antibacterial agents
DOP2006000268A (es) * 2005-12-22 2007-07-31 Pfizer Prod Inc Agentes antibacterianos
US8658641B2 (en) 2008-10-14 2014-02-25 Astrazeneca Ab Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections

Also Published As

Publication number Publication date
EP2350077B1 (en) 2016-01-27
HK1160127A1 (zh) 2012-08-10
CL2011000838A1 (es) 2011-10-21
WO2010043893A1 (en) 2010-04-22
BRPI0920180B1 (pt) 2021-10-26
TW201020258A (en) 2010-06-01
ES2565611T3 (es) 2016-04-05
ECSP11010980A (es) 2011-05-31
JP2015178510A (ja) 2015-10-08
CU20110083A7 (es) 2013-05-31
CA2736335C (en) 2017-05-09
BRPI0920180A2 (pt) 2020-12-29
KR101676886B1 (ko) 2016-11-16
CN104086565A (zh) 2014-10-08
JP5749169B2 (ja) 2015-07-15
US8658641B2 (en) 2014-02-25
EP2350077A1 (en) 2011-08-03
US20110245224A1 (en) 2011-10-06
CN102245605B (zh) 2016-01-27
AU2009305203A1 (en) 2010-04-22
CN102245605A (zh) 2011-11-16
AR073862A1 (es) 2010-12-09
KR20110090895A (ko) 2011-08-10
HK1203483A1 (en) 2015-10-30
CR20110195A (es) 2011-06-08
MX2011003598A (es) 2011-04-27
JP2012505261A (ja) 2012-03-01
EA201100613A1 (ru) 2011-12-30
AU2009305203B2 (en) 2013-03-07
ZA201103533B (en) 2012-01-25
CA2736335A1 (en) 2010-04-22
CO6382126A2 (es) 2012-02-15
DOP2011000102A (es) 2011-05-15
IL211728A0 (en) 2011-06-30

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Legal Events

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Effective date: 20180919