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UA103335C2 - Способ изготовления добавки для ферментативного расщепления микотоксинов, добавка и ее применение - Google Patents

Способ изготовления добавки для ферментативного расщепления микотоксинов, добавка и ее применение

Info

Publication number
UA103335C2
UA103335C2 UAA201104622A UAA201104622A UA103335C2 UA 103335 C2 UA103335 C2 UA 103335C2 UA A201104622 A UAA201104622 A UA A201104622A UA A201104622 A UAA201104622 A UA A201104622A UA 103335 C2 UA103335 C2 UA 103335C2
Authority
UA
Ukraine
Prior art keywords
additive
mycotoxins
producing
enzymatically decomposing
sequence
Prior art date
Application number
UAA201104622A
Other languages
English (en)
Ukrainian (uk)
Inventor
Вульф-Дитер МОЛЛЬ
Дорис ХАРТИНГЕР
Карин ГРИССЛЕР
Ева Мария БИНДЕР
Герд Шатцмайр
Original Assignee
Эрбер Акциенгезельшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эрбер Акциенгезельшафт filed Critical Эрбер Акциенгезельшафт
Publication of UA103335C2 publication Critical patent/UA103335C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01087—Fumonisin B1 esterase (3.1.1.87)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Изобретение относится к способу изготовления добавки для ферментативного расщепления фумонизинов в растительном сырье. Согласно изобретению, обеспечивают как минимум одну нуклеиновокислотную последовательность генов, которая соответствует последовательностям SEQ ID NOs:8, 18 и 24, как минимум, одну последовательность нуклеиновых кислот экспрессируют в прокариотических или эукариотических клетках и используют, как минимум, один приготовленный таким способом фермент, который соответствует последовательностям SEQ ID NOs:9, 19 и 25 вместе с кофактором для расщепления фумонизинов в растительном сырье.
UAA201104622A 2008-09-18 2009-09-18 Способ изготовления добавки для ферментативного расщепления микотоксинов, добавка и ее применение UA103335C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT5012008 2008-09-18
PCT/AT2009/000364 WO2010031101A1 (de) 2008-09-18 2009-09-18 Verfahren zur herstellung eines zuatzstoffes für den enzymatischen abbau von mykotoxinen sowie zusatzstoff und verwendung desselben

Publications (1)

Publication Number Publication Date
UA103335C2 true UA103335C2 (ru) 2013-10-10

Family

ID=41549865

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201104622A UA103335C2 (ru) 2008-09-18 2009-09-18 Способ изготовления добавки для ферментативного расщепления микотоксинов, добавка и ее применение

Country Status (16)

Country Link
US (1) US8703460B2 (ru)
EP (2) EP2326713B8 (ru)
JP (1) JP5833442B2 (ru)
CN (1) CN102159706B (ru)
AR (1) AR073602A1 (ru)
BR (1) BRPI0919406B1 (ru)
CA (1) CA2736566C (ru)
DK (2) DK2326713T3 (ru)
ES (2) ES2643541T3 (ru)
HU (2) HUE033878T2 (ru)
MX (1) MX2011002742A (ru)
PL (2) PL2326713T3 (ru)
RU (1) RU2481397C2 (ru)
UA (1) UA103335C2 (ru)
WO (1) WO2010031101A1 (ru)
ZA (1) ZA201102068B (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102827881B (zh) * 2012-09-11 2013-11-27 国家粮食局科学研究院 一种粮食和/或其副产物中真菌毒素的生物降解方法
HUE046772T2 (hu) * 2015-02-24 2020-03-30 Erber Ag Fuzáriumtoxint hasító polipeptid-variánsok, ezt tartalmazó adalékok, alkalmazásuk és eljárások fuzáriumtoxinok hasítására
JP6646680B2 (ja) * 2015-03-27 2020-02-14 エルベル・アクチエンゲゼルシヤフト トリコテセン変換アルコールデヒドロゲナーゼの使用、トリコテセンの変換方法およびトリコテセン変換添加物
CN108251399B (zh) * 2016-12-29 2020-08-21 中粮营养健康研究院有限公司 伏马毒素降解酶、编码基因、重组载体、细胞、添加剂及其应用
CN108251405B (zh) * 2016-12-29 2020-08-21 中粮营养健康研究院有限公司 复合酶和添加剂及它们的应用以及脱除真菌毒素的方法
ES2847202T3 (es) 2017-07-20 2021-08-02 Tolsa Sa Composición para la unión de micotoxinas y su uso
CN109337886B (zh) * 2018-10-09 2021-07-20 天津科技大学 伏马毒素降解酶FumDXA及其基因和应用
CN109439640B (zh) * 2018-10-09 2021-07-20 天津科技大学 伏马毒素降解酶FumDSB及其基因和应用
CN109439639B (zh) * 2018-10-09 2021-07-20 天津科技大学 伏马毒素降解酶FumDPS及其基因和应用
US20210403841A1 (en) 2020-03-12 2021-12-30 Poet Research, Inc. Enzymatic degradation of mycotoxins during grain processing
CN111549007B (zh) * 2020-04-07 2022-10-04 天津科技大学 一种转氨酶tsta、制备方法和应用
CN111607575B (zh) * 2020-04-07 2022-10-04 天津科技大学 一种转氨酶phta、制备方法和应用
CN113774040B (zh) * 2020-11-24 2022-05-31 中国科学院上海营养与健康研究所 B族伏马菌素降解酶、其构建方法及其应用
WO2023144753A2 (en) * 2022-01-26 2023-08-03 Danstar Ferment Ag Recombinant expression of fumonisin esterase, compositions and uses thereof
EP4357460A1 (en) 2022-10-21 2024-04-24 Consejo Superior De Investigaciones Científicas Fumonisin enzymatic degradation
KR102699553B1 (ko) * 2022-12-29 2024-08-28 씨제이제일제당 주식회사 신규한 푸모니신 분해 효소 및 그의 용도
WO2024180045A1 (en) 2023-02-28 2024-09-06 Dsm Ip Assets B.V. Means and methods for modifying fumonisins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151290C2 (de) * 1981-12-24 1986-08-14 Ernst Leitz Wetzlar Gmbh, 6330 Wetzlar Lamelle für lichtoptische Verschlüsse optischer Geräte
FR2529064B1 (fr) * 1982-06-28 1986-11-07 Guinard Michel Vitrine d'exposition d'objets precieux tels que des bijoux
AU733307B2 (en) 1997-07-07 2001-05-10 Pioneer Hi-Bred International, Inc. Fumonisin detoxification compositions and methods
AU4977099A (en) * 1998-07-15 2000-02-07 Curagen Corporation Amino polyol amine oxidase polynucleotides and related polypeptides and methods of use
US6538177B1 (en) * 1998-07-15 2003-03-25 Pioneer Hi-Bred International, Inc. Compositions and methods for fumonisin detoxification
WO2004085624A2 (en) 2003-03-24 2004-10-07 Diversa Corporation Transaminases, deaminases and aminomutases and compositions and methods for enzymatic detoxification
AT501359B1 (de) * 2004-11-16 2007-10-15 Erber Ag Verfahren und mikroorganismus zur entgiftung von fumonisinen sowie verwendung und futtermittelzusatz

Also Published As

Publication number Publication date
EP2896691A1 (de) 2015-07-22
CA2736566A1 (en) 2010-03-25
RU2011115100A (ru) 2012-10-27
WO2010031101A1 (de) 2010-03-25
US20110189755A1 (en) 2011-08-04
EP2326713B8 (de) 2016-02-17
ES2563084T3 (es) 2016-03-10
AR073602A1 (es) 2010-11-17
CN102159706B (zh) 2013-10-23
EP2326713B1 (de) 2015-11-25
RU2481397C2 (ru) 2013-05-10
ZA201102068B (en) 2011-12-28
JP5833442B2 (ja) 2015-12-16
US8703460B2 (en) 2014-04-22
EP2326713A1 (de) 2011-06-01
BRPI0919406B1 (pt) 2021-01-19
HUE033878T2 (hu) 2018-01-29
MX2011002742A (es) 2011-08-17
BRPI0919406A2 (pt) 2016-05-17
DK2326713T3 (da) 2016-02-29
HUE026735T2 (en) 2016-07-28
DK2896691T3 (en) 2017-10-23
CA2736566C (en) 2018-01-02
CN102159706A (zh) 2011-08-17
PL2326713T3 (pl) 2016-05-31
EP2896691B1 (de) 2017-07-12
PL2896691T3 (pl) 2018-01-31
JP2012502633A (ja) 2012-02-02
ES2643541T3 (es) 2017-11-23

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