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UA104849C2 - 4-піразоліл-n-арилпіримідин-2-аміни і 4-піразоліл-n-гетероарилпіримідин-2-аміни як інгібітори кіназ janus - Google Patents

4-піразоліл-n-арилпіримідин-2-аміни і 4-піразоліл-n-гетероарилпіримідин-2-аміни як інгібітори кіназ janus

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Publication number
UA104849C2
UA104849C2 UAA201007505A UAA201007505A UA104849C2 UA 104849 C2 UA104849 C2 UA 104849C2 UA A201007505 A UAA201007505 A UA A201007505A UA A201007505 A UAA201007505 A UA A201007505A UA 104849 C2 UA104849 C2 UA 104849C2
Authority
UA
Ukraine
Prior art keywords
pyrazolyl
amines
heteroarylpyrimidin
arylpyrimidin
inhibitors
Prior art date
Application number
UAA201007505A
Other languages
English (en)
Russian (ru)
Inventor
Юнь-Лун Лі
Веньцин Яо
Джеймс Д. Роджерс
Original Assignee
Інсайт Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40380038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA104849(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Інсайт Корпорейшн filed Critical Інсайт Корпорейшн
Publication of UA104849C2 publication Critical patent/UA104849C2/uk

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Abstract

Даний винахід стосується заміщених біциклічних гетероарильних сполук формули (І), включаючи, наприклад, 4-піразоліл-N-арилпіримідин-2-аміни і 4-піразоліл-N-гетероарилпіримідин-2-аміни, які модулюють активність кіназ і застосовні при лікуванні захворювань, пов'язаних з активністю кіназ, включаючи, наприклад, хвороби, пов'язані з імунітетом, шкірні розлади, мієлоїднопроліферативні розлади, рак і інші захворювання.I
UAA201007505A 2007-11-16 2008-11-13 4-піразоліл-n-арилпіримідин-2-аміни і 4-піразоліл-n-гетероарилпіримідин-2-аміни як інгібітори кіназ janus UA104849C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98860607P 2007-11-16 2007-11-16
PCT/US2008/083319 WO2009064835A1 (en) 2007-11-16 2008-11-13 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors

Publications (1)

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UA104849C2 true UA104849C2 (uk) 2014-03-25

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Families Citing this family (106)

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Publication number Priority date Publication date Assignee Title
US20060106020A1 (en) * 2004-04-28 2006-05-18 Rodgers James D Tetracyclic inhibitors of Janus kinases
MX346183B (es) 2005-12-13 2017-03-10 Incyte Holdings Corp Pirrolo[2,3-b]piridinas y pirrolo[2,3-b]pirimidinas heteroarilo-sustituidas como inhibidores de cinasas janus.
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