Nothing Special   »   [go: up one dir, main page]

TW200639173A - Substituted pyrazolopyridines, compositions containing same, manufacturing process therefor and use thereof - Google Patents

Substituted pyrazolopyridines, compositions containing same, manufacturing process therefor and use thereof

Info

Publication number
TW200639173A
TW200639173A TW095101823A TW95101823A TW200639173A TW 200639173 A TW200639173 A TW 200639173A TW 095101823 A TW095101823 A TW 095101823A TW 95101823 A TW95101823 A TW 95101823A TW 200639173 A TW200639173 A TW 200639173A
Authority
TW
Taiwan
Prior art keywords
compositions containing
manufacturing process
containing same
process therefor
substituted pyrazolopyridines
Prior art date
Application number
TW095101823A
Other languages
English (en)
Inventor
Baptiste Ronan
Michel Tabart
Franck Halley
Eric Bacque
Catherine Souaille
Antonio Ugolini
Fabrice Viviani
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36593766&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200639173(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR0500555A external-priority patent/FR2880891B1/fr
Priority claimed from FR0507505A external-priority patent/FR2888579A1/fr
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of TW200639173A publication Critical patent/TW200639173A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW095101823A 2005-01-19 2006-01-18 Substituted pyrazolopyridines, compositions containing same, manufacturing process therefor and use thereof TW200639173A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0500555A FR2880891B1 (fr) 2005-01-19 2005-01-19 Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation
FR0507505A FR2888579A1 (fr) 2005-07-13 2005-07-13 Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
TW200639173A true TW200639173A (en) 2006-11-16

Family

ID=36593766

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095101823A TW200639173A (en) 2005-01-19 2006-01-18 Substituted pyrazolopyridines, compositions containing same, manufacturing process therefor and use thereof

Country Status (24)

Country Link
US (2) US8008322B2 (zh)
EP (1) EP1845978B1 (zh)
JP (1) JP2008527025A (zh)
KR (1) KR20070098923A (zh)
AR (1) AR052357A1 (zh)
AT (1) ATE477799T1 (zh)
AU (1) AU2006207442A1 (zh)
BR (1) BRPI0606504A2 (zh)
CA (1) CA2595041A1 (zh)
CY (1) CY1110926T1 (zh)
DE (1) DE602006016233D1 (zh)
DK (1) DK1845978T3 (zh)
HR (1) HRP20100624T8 (zh)
IL (1) IL184524A0 (zh)
MX (1) MX2007008790A (zh)
PA (1) PA8660301A1 (zh)
PE (1) PE20061119A1 (zh)
PL (1) PL1845978T3 (zh)
PT (1) PT1845978E (zh)
RU (1) RU2375360C2 (zh)
SI (1) SI1845978T1 (zh)
TW (1) TW200639173A (zh)
UY (1) UY29341A1 (zh)
WO (1) WO2006077319A1 (zh)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2871158A1 (fr) 2004-06-04 2005-12-09 Aventis Pharma Sa Indazoles substitues, compositions les contenant, procede de fabrication et utilisation
FR2889526B1 (fr) 2005-08-04 2012-02-17 Aventis Pharma Sa 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation
EP1870410A1 (en) * 2006-06-13 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
TW200815438A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
WO2008071456A2 (en) * 2006-12-15 2008-06-19 Bayer Schering Pharma Aktiengesellschaft 3-h-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
EP1932845A1 (en) * 2006-12-15 2008-06-18 Bayer Schering Pharma Aktiengesellschaft 3-H-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
EP2042500A1 (en) * 2007-09-21 2009-04-01 Bayer Schering Pharma Aktiengesellschaft N-[4-(1-H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-N'-[(hetero)aryl]-urea compounds, pharmaceutical compositions comprising them, their preparation and their use as Tie2-kinase inhibitors
WO2009046448A1 (en) 2007-10-04 2009-04-09 Intellikine, Inc. Chemical entities and therapeutic uses thereof
ES2389992T3 (es) * 2007-11-02 2012-11-05 Vertex Pharmaceuticals Incorporated Derivados de [1H-pirazolo[3,4-b]piridin-4-il]-fenilo o -piridin-2-ilo como proteína cinasa c-theta
EP2070929A1 (en) 2007-12-11 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
CA2711614A1 (en) 2008-01-08 2009-07-16 Array Biopharma Inc. Pyrrolopyridines as kinase inhibitors
US8372842B2 (en) 2008-01-09 2013-02-12 Array Biopharma Inc. Pyrazolopyridines as kinase inhibitors
JP5547099B2 (ja) * 2008-03-14 2014-07-09 インテリカイン， エルエルシー キナーゼ阻害剤および使用方法
WO2009114874A2 (en) 2008-03-14 2009-09-17 Intellikine, Inc. Benzothiazole kinase inhibitors and methods of use
MX2011000216A (es) 2008-07-08 2011-03-29 Intellikine Inc Inhibidores de cinasa y metodos para su uso.
US8476431B2 (en) * 2008-11-03 2013-07-02 Itellikine LLC Benzoxazole kinase inhibitors and methods of use
CN102428084B (zh) * 2009-03-19 2016-05-18 医疗技术研究局 化合物
EP2789615B1 (en) 2009-08-11 2017-05-03 Bristol-Myers Squibb Company Azaindazoles as Btk kinase modulators and use thereof
US8222416B2 (en) * 2009-12-14 2012-07-17 Hoffmann-La Roche Inc. Azaindole glucokinase activators
GB201008134D0 (en) * 2010-05-14 2010-06-30 Medical Res Council Technology Compounds
JP2013532688A (ja) 2010-07-26 2013-08-19 ブリストル−マイヤーズ スクイブ カンパニー Ｃｙｐ１７阻害剤として有用なスルホンアミド化合物
GB201015949D0 (en) * 2010-09-22 2010-11-03 Medical Res Council Technology Compounds
EP2638041B1 (en) 2010-11-12 2015-07-22 Bristol-Myers Squibb Company Substituted azaindazole compounds
WO2012148540A1 (en) 2011-02-23 2012-11-01 Intellikine, Llc Combination of kanase inhibitors and uses threof
US20140161720A1 (en) * 2011-05-26 2014-06-12 The General Hospital Corporation Treatment of angiogenic- or vascular-associated diseases
MX355852B (es) * 2011-08-12 2018-05-02 Hoffmann La Roche Compuestos de pirazolo [3,4-c] piridina y métodos de uso.
US9085578B2 (en) 2012-02-20 2015-07-21 Takeda Pharmaceutical Company Limited Heterocyclic compound
EP2900241B1 (en) * 2012-09-28 2018-08-08 Merck Sharp & Dohme Corp. Novel compounds that are erk inhibitors
ES2696700T3 (es) * 2012-12-28 2019-01-17 Crystalgenomics Inc Derivado de 2,3-dihidro-isoindol-1-on como supresor de quinasa BTK y composición farmacéutica que incluye el mismo
TWI629275B (zh) * 2013-03-13 2018-07-11 賽諾菲公司 Ｎ－（４－（氮雜吲唑－６－基）－苯基）－磺醯胺及其作為醫藥之用途
CN103524421B (zh) * 2013-09-29 2015-04-01 镇江蓝德特药业科技有限公司 新型萘脲类衍生物及其医疗应用
US11873303B2 (en) 2018-04-05 2024-01-16 Merck Patent Gmbh Substituted pyrazoles as type II IRAK inhibitors
UY38349A (es) 2018-08-30 2020-03-31 Array Biopharma Inc Compuestos de pirazolo[3,4-b]piridina como inhibidores de cinasas tam y met
KR20240150419A (ko) * 2021-12-22 2024-10-15 아낙시스 파마 피티와이 엘티디 아릴설폰아미드 화합물

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1182896B (de) * 1963-04-02 1964-12-03 Merck Ag E Fungizide Mittel
PL354241A1 (en) 1999-09-17 2003-12-29 Abbott Gmbh & Co.Kgabbott Gmbh & Co.Kg Kinase inhibitors as therapeutic agents
CA2415899A1 (en) * 2000-07-18 2003-01-13 Chikashi Saitoh Medicine comprising dicyanopyridine derivative
PL213199B1 (pl) * 2000-08-10 2013-01-31 Pharmacia Italia Spa Zwiazek bicyklo-pirazolowy, sposób wytwarzania go, jego kompozycja farmaceutyczna, oraz kombinatoryczna biblioteka chemiczna
JP4272338B2 (ja) * 2000-09-22 2009-06-03 バイエル アクチェンゲゼルシャフト ピリジン誘導体
FR2827603B1 (fr) 2001-07-18 2003-10-17 Oreal Composes derives de diaminopyrazole substitues par un radical heteroaromatique et leur utilisation en teinture d'oxydation des fibres keratiniques
GB0128287D0 (en) * 2001-11-26 2002-01-16 Smithkline Beecham Plc Novel method and compounds
AU2003254051A1 (en) * 2002-07-23 2004-02-09 Smithkline Beecham Corporation Pyrazolopyrimidines as kinase inhibitors
US7186716B2 (en) * 2002-08-12 2007-03-06 Sugen, Inc. 3-Pyrrol-pyridopyrazoles and 3-pyrrolyl-indazoles as novel kinase inhibitors
WO2004076450A1 (en) * 2003-02-27 2004-09-10 J. Uriach Y Compañia S.A. Pyrazolopyridine derivates
US7638530B2 (en) 2003-04-24 2009-12-29 Merck & Co., Inc. Inhibitors of Akt activity
ATE469888T1 (de) * 2003-05-22 2010-06-15 Abbott Lab Indazol-, benzisoxazol- und benzisothiazol- kinaseinhibitoren
CA2532800C (en) 2003-07-23 2013-06-18 Exelixis, Inc. Anaplastic lymphoma kinase modulators and methods of use
JP2005325099A (ja) * 2004-04-12 2005-11-24 Sankyo Co Ltd チエノピリジン誘導体
MXPA06013250A (es) * 2004-05-14 2007-02-28 Abbott Lab Inhibidores de quinasa como agentes terapeuticos.
FR2871158A1 (fr) * 2004-06-04 2005-12-09 Aventis Pharma Sa Indazoles substitues, compositions les contenant, procede de fabrication et utilisation
EP1807424B1 (en) * 2004-10-29 2012-04-18 Abbott Laboratories Novel kinase inhibitors
US7563781B2 (en) 2005-01-14 2009-07-21 Janssen Pharmaceutica Nv Triazolopyrimidine derivatives
EP1683796A1 (en) * 2005-01-24 2006-07-26 Schering Aktiengesellschaft Pyrazolopyridines, their preparation and their medical use
EP1863766B1 (en) 2005-03-10 2015-05-20 Gilead Connecticut, Inc. Certain substituted amides, method of making, and method of use thereof
FR2889526B1 (fr) 2005-08-04 2012-02-17 Aventis Pharma Sa 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation
CN101316849A (zh) 2005-11-09 2008-12-03 记忆药物公司 1h-吲唑、苯并噻唑、1,2-苯并异噁唑、1,2-苯并异噻唑和色酮及其制备和用途
EP1870410A1 (en) * 2006-06-13 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
TW200815437A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted aminopyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
TW200815438A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same

Also Published As

Publication number Publication date
JP2008527025A (ja) 2008-07-24
EP1845978A1 (fr) 2007-10-24
PT1845978E (pt) 2010-11-29
PL1845978T3 (pl) 2011-02-28
KR20070098923A (ko) 2007-10-05
CA2595041A1 (fr) 2006-07-27
ATE477799T1 (de) 2010-09-15
PA8660301A1 (es) 2006-09-08
AU2006207442A1 (en) 2006-07-27
SI1845978T1 (sl) 2010-12-31
RU2007131274A (ru) 2009-02-27
IL184524A0 (en) 2007-10-31
HRP20100624T1 (hr) 2010-12-31
DE602006016233D1 (de) 2010-09-30
CY1110926T1 (el) 2015-06-10
US20110190337A1 (en) 2011-08-04
AR052357A1 (es) 2007-03-14
PE20061119A1 (es) 2006-11-27
BRPI0606504A2 (pt) 2009-06-30
US20080039491A1 (en) 2008-02-14
WO2006077319A1 (fr) 2006-07-27
RU2375360C2 (ru) 2009-12-10
EP1845978B1 (fr) 2010-08-18
HRP20100624T8 (en) 2011-01-31
US8008322B2 (en) 2011-08-30
DK1845978T3 (da) 2010-12-13
MX2007008790A (es) 2007-09-11
UY29341A1 (es) 2006-08-31

Similar Documents

Publication Publication Date Title
TW200639173A (en) Substituted pyrazolopyridines, compositions containing same, manufacturing process therefor and use thereof
TW200718701A (en) Substituted pyrrolopyridines, compositions containing same, manufacturing process therefor and use thereof
UA94417C2 (ru) Замещенные 7-азаиндазолы, композиция, которая их содержит, и применение
TW200800999A (en) Novel compounds
TW200801003A (en) Novel compounds
TW200738659A (en) Novel compounds
TW200626593A (en) Novel compounds
TW200745084A (en) Novel compounds
MX2009010047A (es) Compuestos quimicos.
TW200640857A (en) Substituted pyrroles and imidazoles, compositions containing same, manufacturing process therefor and use thereof
TW200745114A (en) Novel compounds
MX2009010045A (es) Compuestos quimicos.
TW200732340A (en) Novel forms of tiotropium bromide and processes for preparation thereof
TW200621777A (en) New dihydropteridione derivatives, process for their manufacture and their use as medicament
TW200800967A (en) Benzimidazole thiophene compounds
TW200700391A (en) Pyridine-2-carboxamide derivatives as mglur5 antagonists
TW200745122A (en) New compounds I
TW200726758A (en) New pyridine analogues
TW200508197A (en) Indolone-acetamide derivatives, processes for preparing them and their uses
DE602004024213D1 (en) Aminopropanolderivate
TW200510344A (en) Aryl-heteroaromatic products, compositions comprising them and use
MX2010009927A (es) Derivados de espiroindolinona.
TW200726763A (en) Novel compound
DOP2006000015A (es) Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricación
MX2009000768A (es) Lactamas macrociclicas.