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TR201307748A2 - Design of Terbinafine Hydrochloride Loaded Liposome Included Pullulan Film System For Ungual Treatment of Onychomycosis - Google Patents

Design of Terbinafine Hydrochloride Loaded Liposome Included Pullulan Film System For Ungual Treatment of Onychomycosis

Info

Publication number
TR201307748A2
TR201307748A2 TR2013/07748A TR201307748A TR201307748A2 TR 201307748 A2 TR201307748 A2 TR 201307748A2 TR 2013/07748 A TR2013/07748 A TR 2013/07748A TR 201307748 A TR201307748 A TR 201307748A TR 201307748 A2 TR201307748 A2 TR 201307748A2
Authority
TR
Turkey
Prior art keywords
onychomycosis
treatment
ungual
design
terbinafine hydrochloride
Prior art date
Application number
TR2013/07748A
Other languages
Turkish (tr)
Inventor
Özgen Özer Kevser
Tuncay Tanriverdi̇ Saki̇ne
Original Assignee
Ege Ueniversitesi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ege Ueniversitesi filed Critical Ege Ueniversitesi
Priority to TR2013/07748A priority Critical patent/TR201307748A2/en
Priority to PCT/TR2014/000228 priority patent/WO2014209246A1/en
Publication of TR201307748A2 publication Critical patent/TR201307748A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)

Abstract

Onikomikoz sistemik olarak kullanılan Terbinafin hidroklomr ile tedavi edilebilmektedir Fakat sistemik tedavi sonucu ortaya çıkan yan etkiler topikal tedaviyi gerekli kılmaktadır Tırnak plağının güçlü bariyer yapısı topikal tedavinin etkinliğini azaltmaktadır Bu çalışmada, onikomikozun ungual tedavisi için Terbinafin hidroklorür içeren lipozom formulasyonun yüklü olduğu Pullulan film formülasyonu tasarlanmıştır.Onychomycosis can be treated systemically with Terbinafine hydrochloride, but side effects resulting from systemic treatment necessitate topical treatment.

TR2013/07748A 2013-06-27 2013-06-27 Design of Terbinafine Hydrochloride Loaded Liposome Included Pullulan Film System For Ungual Treatment of Onychomycosis TR201307748A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2013/07748A TR201307748A2 (en) 2013-06-27 2013-06-27 Design of Terbinafine Hydrochloride Loaded Liposome Included Pullulan Film System For Ungual Treatment of Onychomycosis
PCT/TR2014/000228 WO2014209246A1 (en) 2013-06-27 2014-06-27 Design of terbinafine hydrochloride loaded liposome included pullulan film system for ungual treatment of onychomycosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2013/07748A TR201307748A2 (en) 2013-06-27 2013-06-27 Design of Terbinafine Hydrochloride Loaded Liposome Included Pullulan Film System For Ungual Treatment of Onychomycosis

Publications (1)

Publication Number Publication Date
TR201307748A2 true TR201307748A2 (en) 2014-09-22

Family

ID=51398840

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2013/07748A TR201307748A2 (en) 2013-06-27 2013-06-27 Design of Terbinafine Hydrochloride Loaded Liposome Included Pullulan Film System For Ungual Treatment of Onychomycosis

Country Status (2)

Country Link
TR (1) TR201307748A2 (en)
WO (1) WO2014209246A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018253392B2 (en) 2017-04-14 2023-11-02 Capsugel Belgium Nv Process for making pullulan
CN110678170A (en) 2017-04-14 2020-01-10 比利时胶囊公司 Pullulan polysaccharide capsule
RU2706115C1 (en) * 2018-11-19 2019-11-14 Николай Андреевич Комиссаренко Antifungal and antimicrobial agent of complex action
CN113262310A (en) * 2021-03-02 2021-08-17 宿迁市第一人民医院 Pullulan-modified ginsenoside Rg3Nanostructured lipid carriers and methods of making the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012516320A (en) * 2009-01-30 2012-07-19 イッスム リサーチ デベロプメント カンパニー オブ ザ ヘブライ ユニバーシティ オブ エルサレム リミテッド Composition for treating nails and skin

Also Published As

Publication number Publication date
WO2014209246A1 (en) 2014-12-31

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