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TR200101507T2 - Geniş antibakteriyel spektrumu olan imidazo[4,5-b] piridinyummetil-içerikli sefem bileşimleri - Google Patents

Geniş antibakteriyel spektrumu olan imidazo[4,5-b] piridinyummetil-içerikli sefem bileşimleri

Info

Publication number
TR200101507T2
TR200101507T2 TR2001/01507T TR200101507T TR200101507T2 TR 200101507 T2 TR200101507 T2 TR 200101507T2 TR 2001/01507 T TR2001/01507 T TR 2001/01507T TR 200101507 T TR200101507 T TR 200101507T TR 200101507 T2 TR200101507 T2 TR 200101507T2
Authority
TR
Turkey
Prior art keywords
hydrogen
pyridiniummethyl
cefem
imidazo
compositions
Prior art date
Application number
TR2001/01507T
Other languages
English (en)
Inventor
Nishitani Yasuhiro
Itani Hikaru
Irie Tadashi
Original Assignee
Shionogi & Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co., Ltd. filed Critical Shionogi & Co., Ltd.
Publication of TR200101507T2 publication Critical patent/TR200101507T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

X'in N veya CY ve Y'nin H veya halojen; R1'in amino veya korumali amino; R'nin hidrojen, tercihe göre ikameli alt alkil, vs; R3'ün hidrojen vs; R4'ün hidrojen, tercihe göre ikameli alt alkil veya tercihe göre ikameli N-içeren heterosiklik grup vs; R5'in hidrojen vs; ve kivrimli çizginin bir sin-veya antiizomerizmi, veya bir karisimi oldugu bir formül (1); sefem bilesimi, MRSA dahil, çesitli patojenik bakterilere karsi genis antibakteriyel spektrum göstermektedir.
TR2001/01507T 1998-11-27 1999-11-25 Geniş antibakteriyel spektrumu olan imidazo[4,5-b] piridinyummetil-içerikli sefem bileşimleri TR200101507T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33670798 1998-11-27

Publications (1)

Publication Number Publication Date
TR200101507T2 true TR200101507T2 (tr) 2001-09-21

Family

ID=18301969

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/01507T TR200101507T2 (tr) 1998-11-27 1999-11-25 Geniş antibakteriyel spektrumu olan imidazo[4,5-b] piridinyummetil-içerikli sefem bileşimleri

Country Status (23)

Country Link
US (2) US6518263B1 (tr)
EP (1) EP1134222B1 (tr)
JP (1) JP3636663B2 (tr)
KR (1) KR100692169B1 (tr)
CN (1) CN100436456C (tr)
AT (1) ATE293114T1 (tr)
AU (1) AU758662B2 (tr)
BR (1) BR9915743A (tr)
CA (1) CA2350905C (tr)
CZ (1) CZ20011719A3 (tr)
DE (1) DE69924751T2 (tr)
ES (1) ES2241374T3 (tr)
HU (1) HUP0200450A3 (tr)
ID (1) ID28740A (tr)
IL (1) IL143314A0 (tr)
NO (1) NO20012554L (tr)
NZ (1) NZ511619A (tr)
PL (1) PL347897A1 (tr)
RU (1) RU2223964C2 (tr)
TR (1) TR200101507T2 (tr)
TW (1) TW526202B (tr)
WO (1) WO2000032606A1 (tr)
ZA (1) ZA200103850B (tr)

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Also Published As

Publication number Publication date
ID28740A (id) 2001-06-28
US20030149014A1 (en) 2003-08-07
WO2000032606A1 (fr) 2000-06-08
NO20012554L (no) 2001-07-27
CN1333776A (zh) 2002-01-30
US6800621B2 (en) 2004-10-05
CN100436456C (zh) 2008-11-26
JP3636663B2 (ja) 2005-04-06
EP1134222A4 (en) 2003-01-29
BR9915743A (pt) 2001-08-21
HUP0200450A2 (hu) 2002-07-29
NZ511619A (en) 2002-11-26
CA2350905A1 (en) 2000-06-08
KR100692169B1 (ko) 2007-03-12
KR20010086058A (ko) 2001-09-07
NO20012554D0 (no) 2001-05-23
US6518263B1 (en) 2003-02-11
AU758662B2 (en) 2003-03-27
DE69924751D1 (de) 2005-05-19
ZA200103850B (en) 2002-05-13
DE69924751T2 (de) 2006-03-09
EP1134222A1 (en) 2001-09-19
HUP0200450A3 (en) 2004-04-28
RU2223964C2 (ru) 2004-02-20
EP1134222B1 (en) 2005-04-13
PL347897A1 (en) 2002-04-22
TW526202B (en) 2003-04-01
ATE293114T1 (de) 2005-04-15
CA2350905C (en) 2007-10-23
AU1409000A (en) 2000-06-19
IL143314A0 (en) 2002-04-21
CZ20011719A3 (cs) 2001-12-12
ES2241374T3 (es) 2005-10-16

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