SK4772003A3 - Estrogen receptor modulators - Google Patents

Estrogen receptor modulators Download PDF

Info

Publication number: SK4772003A3
Authority: SK; Slovakia
Prior art keywords: alkyl; group; mhz; nmr; ppm
Prior art date: 2000-10-19

Application number

SK477-2003A

Other languages

English (en)

Slovak (sk)

Inventor

Frank P Dininno

Helen Y Chen

Seongkon Kim

Jane Y Wu

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-19

Filing date

2001-10-15

Publication date

2003-08-05

2001-10-15 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2003-08-05 Publication of SK4772003A3 publication Critical patent/SK4772003A3/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Obesity (AREA)
Neurology (AREA)
Child & Adolescent Psychology (AREA)
Psychiatry (AREA)
Oncology (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

SK477-2003A 2000-10-19 2001-10-15 Estrogen receptor modulators SK4772003A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24158200P	2000-10-19	2000-10-19
PCT/US2001/042735 WO2002032377A2 (en)	2000-10-19	2001-10-15	Estrogen receptor modulators

Publications (1)

Publication Number	Publication Date
SK4772003A3 true SK4772003A3 (en)	2003-08-05

Family

ID=22911282

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK477-2003A SK4772003A3 (en)	2000-10-19	2001-10-15	Estrogen receptor modulators

Country Status (20)

Country	Link
EP (1)	EP1333827A2 (is)
JP (1)	JP2004511502A (is)
KR (1)	KR20030042020A (is)
CN (1)	CN1469743A (is)
AU (2)	AU2002232381B2 (is)
BG (1)	BG107676A (is)
BR (1)	BR0114689A (is)
CA (1)	CA2424729A1 (is)
EA (1)	EA200300474A1 (is)
EC (1)	ECSP034558A (is)
EE (1)	EE200300153A (is)
HU (1)	HUP0303563A2 (is)
IL (1)	IL154984A0 (is)
IS (1)	IS6761A (is)
MX (1)	MXPA03003485A (is)
NO (1)	NO20031737L (is)
PE (1)	PE20021083A1 (is)
PL (1)	PL361053A1 (is)
SK (1)	SK4772003A3 (is)
WO (1)	WO2002032377A2 (is)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030225132A1 (en) *	2002-04-11	2003-12-04	Dininno Frank P.	Estrogen receptor modulators
JP4554219B2 (ja) *	2002-04-24	2010-09-29	メルク・シャープ・エンド・ドーム・コーポレイション	エストロゲン受容体調節剤
EP1577288B1 (en) *	2002-12-26	2014-07-23	Eisai R&D Management Co., Ltd.	Selective estrogen receptor modulators
JP5368792B2 (ja) *	2005-07-29	2013-12-18	レスバーロジックスコーポレイション	複合疾患の予防および処置のための薬学的組成物および挿入可能な医療用デバイスによるその送達
US8163770B2 (en) *	2005-10-27	2012-04-24	Msd. K. K.	Benzoxathiin derivative
US8053440B2 (en)	2007-02-01	2011-11-08	Resverlogix Corporation	Compounds for the prevention and treatment of cardiovascular diseases
NZ594332A (en)	2009-01-08	2013-09-27	Resverlogix Corp	Compounds for the prevention and treatment of cardiovascular disease
CA3146333A1 (en)	2009-03-18	2010-09-23	Resverlogix Corp.	Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
PL2421533T3 (pl)	2009-04-22	2019-05-31	Resverlogix Corp	Nowe środki przeciwzapalne
DK2580210T5 (en)	2010-06-10	2017-06-19	Seragon Pharmaceuticals Inc	ESTROGEN RECEPTOR MODULATORS AND APPLICATIONS THEREOF
WO2011159769A2 (en)	2010-06-17	2011-12-22	Aragon Pharmaceuticals, Inc.	Indane estrogen receptor modulators and uses thereof
AU2012330885B2 (en)	2011-11-01	2016-10-06	Resverlogix Corp.	Oral immediate release formulations for substituted quinazolinones
EP2791132A4 (en)	2011-12-14	2015-08-05	Seragon Pharmaceuticals Inc	ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
US9073878B2 (en)	2012-11-21	2015-07-07	Zenith Epigenetics Corp.	Cyclic amines as bromodomain inhibitors
US9765039B2 (en)	2012-11-21	2017-09-19	Zenith Epigenetics Ltd.	Biaryl derivatives as bromodomain inhibitors
US9271978B2 (en)	2012-12-21	2016-03-01	Zenith Epigenetics Corp.	Heterocyclic compounds as bromodomain inhibitors
US10111885B2 (en)	2015-03-13	2018-10-30	Resverlogix Corp.	Compositions and therapeutic methods for the treatment of complement-associated diseases

2001
- 2001-10-15 WO PCT/US2001/042735 patent/WO2002032377A2/en not_active Application Discontinuation
- 2001-10-15 IL IL15498401A patent/IL154984A0/xx unknown
- 2001-10-15 MX MXPA03003485A patent/MXPA03003485A/es unknown
- 2001-10-15 PL PL01361053A patent/PL361053A1/xx not_active Application Discontinuation
- 2001-10-15 EE EEP200300153A patent/EE200300153A/xx unknown
- 2001-10-15 SK SK477-2003A patent/SK4772003A3/sk unknown
- 2001-10-15 HU HU0303563A patent/HUP0303563A2/hu unknown
- 2001-10-15 AU AU2002232381A patent/AU2002232381B2/en not_active Ceased
- 2001-10-15 KR KR10-2003-7005518A patent/KR20030042020A/ko not_active Application Discontinuation
- 2001-10-15 AU AU3238102A patent/AU3238102A/xx active Pending
- 2001-10-15 EP EP01987654A patent/EP1333827A2/en not_active Withdrawn
- 2001-10-15 JP JP2002535616A patent/JP2004511502A/ja not_active Withdrawn
- 2001-10-15 CN CNA018176720A patent/CN1469743A/zh active Pending
- 2001-10-15 EA EA200300474A patent/EA200300474A1/ru unknown
- 2001-10-15 BR BR0114689-0A patent/BR0114689A/pt not_active Application Discontinuation
- 2001-10-15 CA CA002424729A patent/CA2424729A1/en not_active Abandoned
2002
- 2002-04-15 PE PE2002000308A patent/PE20021083A1/es not_active Application Discontinuation
2003
- 2003-03-26 BG BG107676A patent/BG107676A/bg unknown
- 2003-03-27 IS IS6761A patent/IS6761A/is unknown
- 2003-04-15 NO NO20031737A patent/NO20031737L/no unknown
- 2003-04-17 EC EC2003004558A patent/ECSP034558A/es unknown

Also Published As

Publication number	Publication date
NO20031737D0 (no)	2003-04-15
IL154984A0 (en)	2003-10-31
WO2002032377A2 (en)	2002-04-25
EP1333827A2 (en)	2003-08-13
AU3238102A (en)	2002-04-29
WO2002032377A3 (en)	2002-08-22
IS6761A (is)	2003-03-27
PL361053A1 (en)	2004-09-20
BR0114689A (pt)	2003-07-01
JP2004511502A (ja)	2004-04-15
BG107676A (bg)	2003-11-28
MXPA03003485A (es)	2003-07-14
ECSP034558A (es)	2003-06-25
HUP0303563A2 (hu)	2004-03-01
KR20030042020A (ko)	2003-05-27
EA200300474A1 (ru)	2003-10-30
EE200300153A (et)	2003-06-16
CA2424729A1 (en)	2002-04-25
NO20031737L (no)	2003-06-19
PE20021083A1 (es)	2002-12-16
AU2002232381B2 (en)	2004-11-18
CN1469743A (zh)	2004-01-21

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