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SG87056A1 - Novel tetrapeptide derivative - Google Patents

Novel tetrapeptide derivative

Info

Publication number
SG87056A1
SG87056A1 SG9905131A SG1999005131A SG87056A1 SG 87056 A1 SG87056 A1 SG 87056A1 SG 9905131 A SG9905131 A SG 9905131A SG 1999005131 A SG1999005131 A SG 1999005131A SG 87056 A1 SG87056 A1 SG 87056A1
Authority
SG
Singapore
Prior art keywords
chem
tetrapeptide derivative
novel tetrapeptide
novel
derivative
Prior art date
Application number
SG9905131A
Other languages
English (en)
Inventor
Sakakibara Kyoichi
Masaaki Gondo
Miyazaki Koichi
Original Assignee
Teikoku Hormone Mfg Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26525532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG87056(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teikoku Hormone Mfg Co Ltd filed Critical Teikoku Hormone Mfg Co Ltd
Publication of SG87056A1 publication Critical patent/SG87056A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG9905131A 1991-08-09 1992-08-06 Novel tetrapeptide derivative SG87056A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22353491 1991-08-09
JP22539191 1991-08-12

Publications (1)

Publication Number Publication Date
SG87056A1 true SG87056A1 (en) 2002-03-19

Family

ID=26525532

Family Applications (1)

Application Number Title Priority Date Filing Date
SG9905131A SG87056A1 (en) 1991-08-09 1992-08-06 Novel tetrapeptide derivative

Country Status (13)

Country Link
US (2) US6004934A (de)
EP (2) EP0934950B1 (de)
JP (1) JP2618597B2 (de)
KR (2) KR0185440B1 (de)
AT (2) ATE215962T1 (de)
AU (2) AU662551B2 (de)
CA (1) CA2115355C (de)
DE (2) DE69232552T2 (de)
DK (2) DK0934950T3 (de)
ES (2) ES2172069T3 (de)
GR (1) GR3033397T3 (de)
SG (1) SG87056A1 (de)
WO (1) WO1993003054A1 (de)

Families Citing this family (55)

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US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
UA45304C2 (uk) * 1992-05-20 2002-04-15 Басф Аг Похідні пептиду або їх солі, фармацевтична композиція
ES2151921T3 (es) * 1992-12-16 2001-01-16 Basf Ag Analogo de dolastatina.
WO1995009864A1 (fr) * 1993-10-01 1995-04-13 Teikoku Hormone Mfg. Co., Ltd. Nouveau derive peptidique
US5599902A (en) * 1994-11-10 1997-02-04 Arizona Board Of Regents Acting On Behalf Of Arizona State University Cancer inhibitory peptides
US5663149A (en) * 1994-12-13 1997-09-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
DK0831100T3 (da) * 1995-04-21 2001-01-02 Teikoku Hormone Mfg Co Ltd Nye peptidderivater
US5807984A (en) * 1995-11-09 1998-09-15 Basf Aktienegesellschaft Oligopeptides, the preparation and use thereof
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
US5939527A (en) * 1996-07-30 1999-08-17 Basf Aktiengesellschaft Tetrapeptides as antitumor agents
US5741892A (en) * 1996-07-30 1998-04-21 Basf Aktiengesellschaft Pentapeptides as antitumor agents
US5965537A (en) * 1997-03-10 1999-10-12 Basf Aktiengesellschaft Dolastatin 15 derivatives with carbonyl and heterocyclic functionalities at the C-terminus
US6103698A (en) 1997-03-13 2000-08-15 Basf Aktiengesellschaft Dolastatin-15 derivatives in combination with taxanes
US6143721A (en) * 1997-07-18 2000-11-07 Basf Aktiengesellschaft Dolastatin 15 derivatives
WO1999015130A2 (en) * 1997-09-24 1999-04-01 ARIZONA BOARD OF REGENTS, actingon behalf of ARIZ ONA STATE UNIVERSITY Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
US6686445B1 (en) 1997-09-24 2004-02-03 Arizona Board Of Regents, Acting For And On Behalf Of Arizona State University Synthetic antineoplastic agents derived from dolastatin 15 and methods of making same
US6015790A (en) * 1997-10-06 2000-01-18 Basf Aktiengesellschaft Methods and compositions for treating rheumatoid arthritis
US5985837A (en) * 1998-07-08 1999-11-16 Basf Aktiengesellschaft Dolastatin 15 derivatives
US6323315B1 (en) 1999-09-10 2001-11-27 Basf Aktiengesellschaft Dolastatin peptides
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
AU1730701A (en) * 1999-12-07 2001-06-18 Santen Pharmaceutical Co. Ltd. Rheumatism remedy containing tetrapeptide derivative as active ingredient
US6884869B2 (en) 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
US7256257B2 (en) 2001-04-30 2007-08-14 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
KR20010079252A (ko) * 2001-06-27 2001-08-22 홍진의 주름형 드럼을 갖는 드럼 필터
DE60228459D1 (de) 2001-09-20 2008-10-02 Teikoku Hormone Mfg Co Ltd Tetrapeptid-derivat-kristalle
EP2353611B1 (de) 2002-07-31 2015-05-13 Seattle Genetics, Inc. Arzneimittelkonjugate und deren Verwendung zur Behandlung von Krebs, einer Autoimmunerkrankung oder einer Infektionskrankheit
SI1725249T1 (sl) 2003-11-06 2014-04-30 Seattle Genetics, Inc. Spojine monometilvalina, sposobne konjugacije na ligande
AU2005332660A1 (en) * 2004-11-12 2006-12-14 Seattle Genetics, Inc. Auristatins having an aminobenzoic acid unit at the N terminus
EP1883627B1 (de) 2005-05-18 2018-04-18 Pharmascience Inc. An die bir-domäne bindende verbindungen
EP2722051B1 (de) 2005-07-07 2018-11-07 Seattle Genetics, Inc. Monomethylvalinverbindungen mit Phenylalaninseitenkettenmodifikationen am C-Terminus
WO2007008848A2 (en) 2005-07-07 2007-01-18 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
US7750116B1 (en) 2006-02-18 2010-07-06 Seattle Genetics, Inc. Antibody drug conjugate metabolites
JP5419685B2 (ja) 2006-05-16 2014-02-19 ファーマサイエンス・インコーポレイテッド Ｉａｐｂｉｒドメイン結合タンパク質
JP2010533495A (ja) 2007-07-16 2010-10-28 ジェネンテック， インコーポレイテッド ヒト化ＣＤ７９ｂ抗体およびイムノコンジュゲートならびにそれらの使用
CN103819560B (zh) 2007-07-16 2017-01-04 健泰科生物技术公司 抗cd79b抗体和免疫偶联物及使用方法
US20090035848A1 (en) * 2007-08-03 2009-02-05 Robert Hickey Moving bed biofilm reactor (mbbr) system for conversion of syngas components to liquid products
IL295449A (en) 2008-01-31 2022-10-01 Genentech Inc and fusion antibody-drug-cd79b engineered antibodies cysteine-
WO2009117531A1 (en) 2008-03-18 2009-09-24 Seattle Genetics, Inc. Auristatin drug linker conjugates
WO2011098904A1 (en) 2010-02-12 2011-08-18 Aegera Therapeutics, Inc. Iap bir domain binding compounds
KR101733853B1 (ko) 2011-11-17 2017-05-08 화이자 인코포레이티드 세포독성 펩티드 및 그의 항체 약물 접합체
AU2013318779B2 (en) * 2012-09-20 2016-07-28 Celltrion, Inc. Dolastatin-10 derivative, method of producing the same and anticancer drug composition containing the same
EP2922818B1 (de) 2012-11-24 2018-09-05 Hangzhou Dac Biotech Co., Ltd Hydrophile binder und deren verwendung zur konjugation von wirkstoffen an zellbindende moleküle
CA2930614A1 (en) 2013-12-17 2015-06-25 Novartis Ag Cytotoxic peptides and conjugates thereof
DK3122757T3 (da) 2014-02-28 2023-10-09 Hangzhou Dac Biotech Co Ltd Ladede linkere og anvendelse deraf til konjugering
US20170190735A1 (en) 2014-05-28 2017-07-06 Agensys, Inc. Derivatives of dolaproine-dolaisoleuine peptides
AU2015273098B2 (en) 2014-06-13 2018-05-10 Novartis Ag Auristatin derivatives and conjugates thereof
HRP20200924T8 (hr) 2014-09-23 2023-07-21 F. Hoffmann - La Roche Ag Postupak primjene imunokonjugata anti-cd79b
CN113350518A (zh) 2015-07-12 2021-09-07 杭州多禧生物科技有限公司 与细胞结合分子的共轭偶联的桥连接体
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
US10435435B2 (en) 2015-07-24 2019-10-08 The Arizona Board Of Regents On Behalf Of Arizona State University Quinstatin compounds
WO2017058808A1 (en) * 2015-10-02 2017-04-06 Sirenas Llc Anti-cancer compounds and conjugates thereof
US10792365B2 (en) 2016-03-29 2020-10-06 Toray Industries, Inc. Peptide derivative and use thereof
US20210308277A1 (en) 2016-11-14 2021-10-07 Hangzhou Dac Biotech Co., Ltd. Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers
US20230000995A1 (en) * 2019-10-28 2023-01-05 Ariel Scientific Innovations Ltd. Dolastatin 10 analog
JPWO2023033129A1 (de) 2021-09-03 2023-03-09

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5017691A (en) * 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US4978744A (en) * 1989-01-27 1990-12-18 Arizona Board Of Regents Synthesis of dolastatin 10
US6034065A (en) * 1992-12-03 2000-03-07 Arizona Board Of Regents Elucidation and synthesis of antineoplastic tetrapeptide phenethylamides of dolastatin 10
US5635483A (en) * 1992-12-03 1997-06-03 Arizona Board Of Regents Acting On Behalf Of Arizona State University Tumor inhibiting tetrapeptide bearing modified phenethyl amides

Also Published As

Publication number Publication date
JP2618597B2 (ja) 1997-06-11
ATE215962T1 (de) 2002-04-15
AU2415292A (en) 1993-03-02
DE69230824T2 (de) 2000-07-27
CA2115355A1 (en) 1993-02-18
ES2172069T3 (es) 2002-09-16
AU673487B2 (en) 1996-11-07
AU662551B2 (en) 1995-09-07
DK0934950T3 (da) 2002-07-29
EP0934950B1 (de) 2002-04-10
GR3033397T3 (en) 2000-09-29
EP0598129A1 (de) 1994-05-25
DE69232552D1 (de) 2002-05-16
KR0185440B1 (ko) 1999-04-01
WO1993003054A1 (en) 1993-02-18
EP0598129A4 (en) 1995-10-25
DE69232552T2 (de) 2002-10-31
DE69230824D1 (de) 2000-04-27
US5654399A (en) 1997-08-05
KR100202474B1 (en) 1999-06-15
ES2144421T3 (es) 2000-06-16
CA2115355C (en) 2007-09-11
ATE190983T1 (de) 2000-04-15
AU2001095A (en) 1995-07-20
DK0598129T3 (da) 2000-07-03
EP0934950A1 (de) 1999-08-11
US6004934A (en) 1999-12-21
EP0598129B1 (de) 2000-03-22

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