SG11201807134RA - Transposon system and methods of use - Google Patents
Transposon system and methods of useInfo
- Publication number
- SG11201807134RA SG11201807134RA SG11201807134RA SG11201807134RA SG11201807134RA SG 11201807134R A SG11201807134R A SG 11201807134RA SG 11201807134R A SG11201807134R A SG 11201807134RA SG 11201807134R A SG11201807134R A SG 11201807134RA SG 11201807134R A SG11201807134R A SG 11201807134RA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- san diego
- california
- pct
- rule
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 210000002865 immune cell Anatomy 0.000 abstract 2
- 102000008579 Transposases Human genes 0.000 abstract 1
- 108010020764 Transposases Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004520 electroporation Methods 0.000 abstract 1
- 238000012239 gene modification Methods 0.000 abstract 1
- 230000005017 genetic modification Effects 0.000 abstract 1
- 235000013617 genetically modified food Nutrition 0.000 abstract 1
- 229910052754 neon Inorganic materials 0.000 abstract 1
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 210000002262 tip cell Anatomy 0.000 abstract 1
- 230000035899 viability Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662300387P | 2016-02-26 | 2016-02-26 | |
| PCT/US2017/019531 WO2017147538A1 (en) | 2016-02-26 | 2017-02-24 | Transposon system and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201807134RA true SG11201807134RA (en) | 2018-09-27 |
Family
ID=58314517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201807134RA SG11201807134RA (en) | 2016-02-26 | 2017-02-24 | Transposon system and methods of use |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3420090A1 (zh) |
| JP (1) | JP2019506177A (zh) |
| KR (1) | KR20180131545A (zh) |
| CN (1) | CN109312361A (zh) |
| AU (1) | AU2017224111A1 (zh) |
| BR (1) | BR112018067536A2 (zh) |
| CA (1) | CA3015642A1 (zh) |
| IL (1) | IL261343A (zh) |
| MX (1) | MX2018010288A (zh) |
| RU (1) | RU2018133691A (zh) |
| SG (1) | SG11201807134RA (zh) |
| WO (1) | WO2017147538A1 (zh) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190119636A1 (en) | 2017-10-23 | 2019-04-25 | Poseida Therapeutics, Inc. | Modified stem cell memory t cells, methods of making and methods of using same |
| US11278570B2 (en) | 2016-12-16 | 2022-03-22 | B-Mogen Biotechnologies, Inc. | Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods |
| US11111483B2 (en) | 2016-12-16 | 2021-09-07 | B-Mogen Biotechnologies, Inc. | Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems and methods |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
| US20210115453A1 (en) * | 2017-08-31 | 2021-04-22 | Poseida Therapeutics, Inc. | Transposon system and methods of use |
| JP2020532987A (ja) * | 2017-09-08 | 2020-11-19 | ポセイダ セラピューティクス，インコーポレイティド | キメラリガンド受容体（ｃｌｒ）介在性の条件遺伝子発現のための組成物および方法 |
| US10329543B2 (en) | 2017-10-23 | 2019-06-25 | Poseida Therapeutics, Inc. | Modified stem cell memory T cells, methods of making and methods of using same |
| CA3104288A1 (en) | 2018-06-21 | 2019-12-26 | B-Mogen Biotechnologies, Inc. | Enhanced hat family transposon-mediated gene transfer and associated compositions, systems, and methods |
| WO2020163755A1 (en) * | 2019-02-08 | 2020-08-13 | Dna Twopointo Inc. | Transposon-based modifications of immune cells |
| CN111926041B (zh) * | 2020-10-16 | 2020-12-25 | 广州吉妮欧生物科技有限公司 | 一种SARS-CoV-2假病毒小鼠体内包装系统及其制备方法 |
| CN114246986B (zh) * | 2021-12-29 | 2022-08-23 | 中国人民解放军陆军军医大学 | 一种基于原位调控免疫反应的心血管植入物及其制备方法 |
| CN118185901A (zh) * | 2022-12-12 | 2024-06-14 | 上海精缮生物科技有限责任公司 | 一种PBase蛋白、融合蛋白、核酸和基因整合系统及应用 |
| CN116590341A (zh) * | 2023-07-13 | 2023-08-15 | 山东维真生物科技有限公司 | 一种腺病毒-PiggyBac系统及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| JP5726522B2 (ja) | 2007-07-04 | 2015-06-03 | マックス−デルブリュック−ツェントルム フューア モレキュラーレ メディツィン | トランスポゾンシステム−スリーピングビューティーのトランスポザーゼタンパク質の機能亢進性バリアント |
| CN102421902A (zh) * | 2009-02-25 | 2012-04-18 | 约翰·霍普金斯大学 | Piggybac转座子变异及其使用方法 |
| EP4442820A2 (en) * | 2009-02-26 | 2024-10-09 | Poseida Therapeutics, Inc. | Hyperactive piggybac transposases |
| US20130045491A1 (en) * | 2011-07-19 | 2013-02-21 | Derya Unutmaz | Methods for activating t cells |
| US20150322439A1 (en) * | 2012-11-19 | 2015-11-12 | Nature Technology Corporation | Replicative minicircle vectors with improved expression |
-
2017
- 2017-02-24 CN CN201780025816.1A patent/CN109312361A/zh active Pending
- 2017-02-24 AU AU2017224111A patent/AU2017224111A1/en not_active Abandoned
- 2017-02-24 SG SG11201807134RA patent/SG11201807134RA/en unknown
- 2017-02-24 WO PCT/US2017/019531 patent/WO2017147538A1/en active Application Filing
- 2017-02-24 KR KR1020187027345A patent/KR20180131545A/ko unknown
- 2017-02-24 MX MX2018010288A patent/MX2018010288A/es unknown
- 2017-02-24 BR BR112018067536A patent/BR112018067536A2/pt not_active IP Right Cessation
- 2017-02-24 RU RU2018133691A patent/RU2018133691A/ru not_active Application Discontinuation
- 2017-02-24 JP JP2018544891A patent/JP2019506177A/ja active Pending
- 2017-02-24 CA CA3015642A patent/CA3015642A1/en not_active Abandoned
- 2017-02-24 EP EP17711046.7A patent/EP3420090A1/en not_active Withdrawn
-
2018
- 2018-08-23 IL IL261343A patent/IL261343A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2018133691A3 (zh) | 2020-07-29 |
| CN109312361A (zh) | 2019-02-05 |
| IL261343A (en) | 2018-10-31 |
| JP2019506177A (ja) | 2019-03-07 |
| RU2018133691A (ru) | 2020-03-26 |
| MX2018010288A (es) | 2019-06-06 |
| WO2017147538A1 (en) | 2017-08-31 |
| KR20180131545A (ko) | 2018-12-10 |
| AU2017224111A1 (en) | 2018-09-13 |
| EP3420090A1 (en) | 2019-01-02 |
| BR112018067536A2 (pt) | 2019-02-05 |
| CA3015642A1 (en) | 2017-08-31 |
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