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SG11201805166PA - Light-mediated polymerase chain reaction amplification and product detection system and methods of use - Google Patents

Light-mediated polymerase chain reaction amplification and product detection system and methods of use

Info

Publication number
SG11201805166PA
SG11201805166PA SG11201805166PA SG11201805166PA SG11201805166PA SG 11201805166P A SG11201805166P A SG 11201805166PA SG 11201805166P A SG11201805166P A SG 11201805166PA SG 11201805166P A SG11201805166P A SG 11201805166PA SG 11201805166P A SG11201805166P A SG 11201805166PA
Authority
SG
Singapore
Prior art keywords
international
iowa
reaction
rule
methods
Prior art date
Application number
SG11201805166PA
Other languages
English (en)
Inventor
Ronald L Biro
Beau Hunt
Original Assignee
Pioneer Hi Bred Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pioneer Hi Bred Int filed Critical Pioneer Hi Bred Int
Publication of SG11201805166PA publication Critical patent/SG11201805166PA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50851Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/021Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a flexible chain, e.g. "cartridge belt", conveyor for reaction cells or cuvettes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/142Preventing evaporation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0812Bands; Tapes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1838Means for temperature control using fluid heat transfer medium
    • B01L2300/1844Means for temperature control using fluid heat transfer medium using fans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1861Means for temperature control using radiation
    • B01L2300/1872Infrared light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/08Optical fibres; light guides
    • G01N2201/0826Fibre array at source, distributing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/08Optical fibres; light guides
    • G01N2201/0833Fibre array at detector, resolving

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Clinical Laboratory Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Peptides Or Proteins (AREA)
  • Dispersion Chemistry (AREA)
SG11201805166PA 2016-03-10 2017-03-08 Light-mediated polymerase chain reaction amplification and product detection system and methods of use SG11201805166PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662306432P 2016-03-10 2016-03-10
PCT/US2017/021359 WO2017156126A1 (fr) 2016-03-10 2017-03-08 Amplification en chaîne par polymérase médiée par la lumière et système de détection de produit et procédés d'utilisation

Publications (1)

Publication Number Publication Date
SG11201805166PA true SG11201805166PA (en) 2018-07-30

Family

ID=58361164

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201805166PA SG11201805166PA (en) 2016-03-10 2017-03-08 Light-mediated polymerase chain reaction amplification and product detection system and methods of use

Country Status (9)

Country Link
US (1) US11369965B2 (fr)
EP (1) EP3426399B1 (fr)
CN (1) CN108778511A (fr)
BR (1) BR112018068139B1 (fr)
CA (1) CA3009080C (fr)
ES (1) ES2871861T3 (fr)
MX (1) MX2018010108A (fr)
SG (1) SG11201805166PA (fr)
WO (1) WO2017156126A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10465495B2 (en) * 2017-10-02 2019-11-05 Petrolog Automation, Inc Polished-rod thermal imaging system for preventing failures in the operation of a sucker rod pump
JP2021518158A (ja) 2018-03-15 2021-08-02 クリプトス バイオテクノロジーズ,インコーポレイテッド 熱支援生化学反応を実施するための方法およびシステム
JP2022504858A (ja) * 2018-10-16 2022-01-13 クリプトス バイオテクノロジーズ,インコーポレイテッド 生化学反応容器の温度監視のための方法およびシステム
WO2020132131A1 (fr) * 2018-12-21 2020-06-25 Kryptos Biotechnologies, Inc. Procédé et système de chauffage et de mesure de la température à l'aide de films minces à motif
EP3903109A4 (fr) * 2018-12-28 2023-03-08 Beckman Coulter, Inc. Diagnostic de système automatisé d'analyseur clinique
GB2586453B (en) * 2019-08-13 2024-04-10 Causeway Sensors Ltd Analyzing system for multi-well sample carriers
WO2021178893A2 (fr) 2020-03-06 2021-09-10 Singular Genomics Systems, Inc. Séquençage de brin apparié lié
EP4208710A4 (fr) * 2020-09-04 2024-10-09 Univ Boston Microscope photothermique à infrarouge moyen codé par fluorescence
CN112285108B (zh) * 2020-10-20 2023-11-21 深圳技术大学 一种基于红外热成像技术的便携式贵金属层间掺假无损检测装置
CN112626185A (zh) * 2020-12-31 2021-04-09 郑州大学第一附属医院 一种快速、便携式荧光定量pcr检测装置及方法
WO2023154897A1 (fr) * 2022-02-11 2023-08-17 Singular Genomics Systems, Inc. Amplification d'acide nucléique et rétention de motif de méthylation
US20230301354A1 (en) * 2022-03-24 2023-09-28 Derek Kyle King Quantum Lit Vaping System
CN115449471B (zh) * 2022-11-10 2023-06-02 南方科技大学 扩增结构、快速核酸检测芯片、装置与方法
KR20240135207A (ko) * 2023-03-03 2024-09-10 한국광기술원 유전자 증폭 검사장치 및 이를 이용하는 검사방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US7081226B1 (en) * 1996-06-04 2006-07-25 University Of Utah Research Foundation System and method for fluorescence monitoring
WO1996041864A1 (fr) 1995-06-13 1996-12-27 The Regents Of The University Of California Chambre de microreaction chauffee par laser a diode dotee d'un moyen de detection d'echantillons
CA2658290C (fr) 1996-06-04 2012-04-10 University Of Utah Research Foundation Controle de l'hybridation pendant la pcr en utilisant un colorant fluorescent specifique a un adn a double brin
US5972667A (en) * 1998-05-19 1999-10-26 Cell Robotics, Inc. Method and apparatus for activating a thermo-enzyme reaction with electromagnetic energy
EP1173284B1 (fr) * 1999-03-25 2010-05-19 AlphaHelix Molecular Diagnostics AB Homogeneisation de petits volumes de melanges de reactions chimiques par centrifugation et chauffage
US6720187B2 (en) * 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices
US7232547B2 (en) * 2002-03-22 2007-06-19 Marshfield Clinic Apparatus and method for testing and continuously reading low-volume samples
US6833536B2 (en) * 2002-05-22 2004-12-21 Applera Corporation Non-contact radiant heating and temperature sensing device for a chemical reaction chamber
AU2003302264A1 (en) * 2002-12-20 2004-09-09 Biotrove, Inc. Assay apparatus and method using microfluidic arrays
EP1541237A3 (fr) * 2003-12-10 2006-02-01 Samsung Electronics Co., Ltd. Module por la pcr et systeme pour la pcr multiple utilisant le dit
US7122799B2 (en) * 2003-12-18 2006-10-17 Palo Alto Research Center Incorporated LED or laser enabled real-time PCR system and spectrophotometer
BRPI0712655A2 (pt) * 2006-06-08 2012-11-20 Koninkl Philips Electronics Nv dispositivo de sensor microeletrânico, mÉtodo para investigaÇço de pelo menos uma substÂncia alvo biolàgica, e, uso do dispositivo de sensor microeletrânico
CN101711257A (zh) * 2007-01-22 2010-05-19 瓦弗根公司 用于高通量化学反应的装置
US9475051B2 (en) * 2007-02-27 2016-10-25 Sony Corporation Nucleic acid amplifier
JP5279481B2 (ja) * 2008-12-25 2013-09-04 株式会社日立ハイテクノロジーズ 核酸分析装置
CN105964312A (zh) * 2010-07-22 2016-09-28 基因细胞生物系统有限公司 复合液体池

Also Published As

Publication number Publication date
CN108778511A (zh) 2018-11-09
EP3426399B1 (fr) 2021-03-10
BR112018068139A2 (pt) 2019-01-15
EP3426399A1 (fr) 2019-01-16
WO2017156126A1 (fr) 2017-09-14
US11369965B2 (en) 2022-06-28
CA3009080C (fr) 2023-10-10
ES2871861T3 (es) 2021-11-02
US20180361379A1 (en) 2018-12-20
BR112018068139B1 (pt) 2022-12-06
CA3009080A1 (fr) 2017-09-14
MX2018010108A (es) 2018-12-17

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