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SE453091B - Nya cefalosporinderivat, forfarande for framstellning derav samt kompositioner derav - Google Patents

Nya cefalosporinderivat, forfarande for framstellning derav samt kompositioner derav

Info

Publication number
SE453091B
SE453091B SE8301178A SE8301178A SE453091B SE 453091 B SE453091 B SE 453091B SE 8301178 A SE8301178 A SE 8301178A SE 8301178 A SE8301178 A SE 8301178A SE 453091 B SE453091 B SE 453091B
Authority
SE
Sweden
Prior art keywords
methyl
compound
cephem
carboxylate
pharmaceutically acceptable
Prior art date
Application number
SE8301178A
Other languages
English (en)
Swedish (sv)
Other versions
SE8301178D0 (sv
SE8301178L (sv
Inventor
S Aburaki
H Kamachi
Y Narita
J Okumura
T Naito
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/354,851 external-priority patent/US4406899A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8301178D0 publication Critical patent/SE8301178D0/xx
Publication of SE8301178L publication Critical patent/SE8301178L/
Publication of SE453091B publication Critical patent/SE453091B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8301178A 1982-03-04 1983-03-03 Nya cefalosporinderivat, forfarande for framstellning derav samt kompositioner derav SE453091B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/354,851 US4406899A (en) 1982-03-04 1982-03-04 Cephalosporins
US35753482A 1982-03-12 1982-03-12

Publications (3)

Publication Number Publication Date
SE8301178D0 SE8301178D0 (sv) 1983-03-03
SE8301178L SE8301178L (sv) 1983-09-05
SE453091B true SE453091B (sv) 1988-01-11

Family

ID=26998584

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8301178A SE453091B (sv) 1982-03-04 1983-03-03 Nya cefalosporinderivat, forfarande for framstellning derav samt kompositioner derav

Country Status (29)

Country Link
KR (1) KR870001986B1 (de)
AT (2) AT382155B (de)
AU (1) AU562776B2 (de)
BE (1) BE896086A (de)
CA (1) CA1213882A (de)
CH (1) CH654313A5 (de)
CS (1) CS249512B2 (de)
DD (1) DD210280A5 (de)
DE (1) DE3307550A1 (de)
DK (1) DK156900C (de)
EG (1) EG15934A (de)
ES (2) ES520224A0 (de)
FI (1) FI74973C (de)
FR (1) FR2522659B1 (de)
GB (1) GB2116180B (de)
GR (1) GR77916B (de)
HU (1) HU193158B (de)
IE (1) IE56647B1 (de)
IL (1) IL68011A0 (de)
IT (1) IT1170307B (de)
LU (1) LU84674A1 (de)
MY (1) MY8700943A (de)
NL (2) NL193284C (de)
NZ (1) NZ203312A (de)
PH (1) PH18002A (de)
PT (1) PT76330B (de)
SE (1) SE453091B (de)
SU (1) SU1250173A3 (de)
YU (2) YU43822B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3404906A1 (de) * 1984-02-11 1985-08-14 Bayer Ag, 5090 Leverkusen 1-oxadethiacephalosporinderivate sowie verfahren zu ihrer herstellung
DE3419013A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
US4698336A (en) * 1985-01-30 1987-10-06 Eisai Co., Ltd. 3-(pyrrolidinio)methyl-3-cephem derivatives
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
CA1284994C (en) * 1985-08-05 1991-06-18 Murray Arthur Kaplan Cephalosporin salts and injectable compositions
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
EP0237735B1 (de) * 1986-03-17 1994-03-30 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituierte-3-Cephemverbindungen und Verfahren zu ihrer Herstellung
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
EP0503453B1 (de) 1991-03-08 2001-05-09 Biochemie Gesellschaft M.B.H. Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
IL103110A (en) * 1991-09-10 1997-04-15 Bristol Myers Squibb Co Anhydrous process for preparing cefepime dihydrochloride hydrate
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
CN100543027C (zh) * 2003-12-23 2009-09-23 桑多斯有限公司 制备用于合成头孢菌素的中间体的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
GB1591439A (en) * 1976-10-01 1981-06-24 Glaxo Operations Ltd 7-syn (oxyimino -acylamido) cephalosporins
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
GB2040921B (en) * 1978-10-27 1982-12-22 Glaxo Group Ltd Cephalosporin antibiotics
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics

Also Published As

Publication number Publication date
ES8403919A1 (es) 1984-04-01
FI830689A0 (fi) 1983-03-01
ES520224A0 (es) 1984-04-01
AT382155B (de) 1987-01-26
CH654313A5 (de) 1986-02-14
DK156900C (da) 1990-03-12
ATA228285A (de) 1987-05-15
FI830689L (fi) 1983-09-05
PT76330B (en) 1986-02-04
NL193284B (nl) 1999-01-04
AT384612B (de) 1987-12-10
ATA76183A (de) 1986-06-15
YU52383A (en) 1986-02-28
GB8305940D0 (en) 1983-04-07
BE896086A (fr) 1983-09-05
AU562776B2 (en) 1987-06-18
DK86283A (da) 1983-09-05
SE8301178D0 (sv) 1983-03-03
FR2522659B1 (fr) 1986-10-24
IE830455L (en) 1983-09-04
ES526397A0 (es) 1985-09-16
ES8507557A1 (es) 1985-09-16
DD210280A5 (de) 1984-06-06
PH18002A (en) 1985-02-28
NL990039I1 (nl) 2000-01-03
CS249512B2 (en) 1987-03-12
MY8700943A (en) 1987-12-31
DK86283D0 (da) 1983-02-24
NL193284C (nl) 1999-05-06
GB2116180A (en) 1983-09-21
FI74973B (fi) 1987-12-31
IE56647B1 (en) 1991-10-23
NL990039I2 (nl) 2000-04-03
DE3307550C2 (de) 1988-11-24
CA1213882A (en) 1986-11-12
IT8347826A0 (it) 1983-03-01
IL68011A0 (en) 1983-06-15
FI74973C (fi) 1988-04-11
DK156900B (da) 1989-10-16
EG15934A (en) 1987-10-30
FR2522659A1 (fr) 1983-09-09
LU84674A1 (fr) 1983-11-17
YU44777B (en) 1991-02-28
NL8300755A (nl) 1983-10-03
PT76330A (en) 1983-04-01
GR77916B (de) 1984-09-25
KR870001986B1 (ko) 1987-10-24
SE8301178L (sv) 1983-09-05
NZ203312A (en) 1985-12-13
AU1130483A (en) 1983-09-08
HU193158B (en) 1987-08-28
KR840004118A (ko) 1984-10-06
YU43822B (en) 1989-12-31
YU149685A (en) 1986-02-28
GB2116180B (en) 1985-09-18
SU1250173A3 (ru) 1986-08-07
IT1170307B (it) 1987-06-03
DE3307550A1 (de) 1983-09-15

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