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SE0102617D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0102617D0
SE0102617D0 SE0102617A SE0102617A SE0102617D0 SE 0102617 D0 SE0102617 D0 SE 0102617D0 SE 0102617 A SE0102617 A SE 0102617A SE 0102617 A SE0102617 A SE 0102617A SE 0102617 D0 SE0102617 D0 SE 0102617D0
Authority
SE
Sweden
Prior art keywords
sub
novel compounds
therapy
processes
formula
Prior art date
Application number
SE0102617A
Other languages
English (en)
Inventor
David Griffiths
Craig Johnstone
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0102617A priority Critical patent/SE0102617D0/sv
Publication of SE0102617D0 publication Critical patent/SE0102617D0/sv
Priority to NZ530751A priority patent/NZ530751A/en
Priority to AT02756047T priority patent/ATE353327T1/de
Priority to IL16002302A priority patent/IL160023A0/xx
Priority to KR10-2004-7001155A priority patent/KR20040018521A/ko
Priority to PCT/SE2002/001402 priority patent/WO2003010163A1/en
Priority to MXPA04000755A priority patent/MXPA04000755A/es
Priority to BR0211472-0A priority patent/BR0211472A/pt
Priority to EP02756047A priority patent/EP1421079B1/en
Priority to CA002454702A priority patent/CA2454702A1/en
Priority to US10/484,645 priority patent/US7098240B2/en
Priority to CNA028152514A priority patent/CN1538968A/zh
Priority to DE60218048T priority patent/DE60218048T2/de
Priority to ES02756047T priority patent/ES2280559T3/es
Priority to JP2003515522A priority patent/JP2004536869A/ja
Priority to ZA200400494A priority patent/ZA200400494B/en
Priority to NO20040314A priority patent/NO20040314L/no
Priority to JP2009291103A priority patent/JP2010111683A/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
SE0102617A 2001-07-25 2001-07-25 Novel compounds SE0102617D0 (sv)

Priority Applications (18)

Application Number Priority Date Filing Date Title
SE0102617A SE0102617D0 (sv) 2001-07-25 2001-07-25 Novel compounds
JP2003515522A JP2004536869A (ja) 2001-07-25 2002-07-19 新規化合物
EP02756047A EP1421079B1 (en) 2001-07-25 2002-07-19 Thiophenyl compounds as medicaments
US10/484,645 US7098240B2 (en) 2001-07-25 2002-07-19 Compounds
IL16002302A IL160023A0 (en) 2001-07-25 2002-07-19 Thiopene carboxamide derivatives, process for their preparation, pharmaceutical compositions containing them and their use in therapy
KR10-2004-7001155A KR20040018521A (ko) 2001-07-25 2002-07-19 신규 화합물
PCT/SE2002/001402 WO2003010163A1 (en) 2001-07-25 2002-07-19 Novel compounds
MXPA04000755A MXPA04000755A (es) 2001-07-25 2002-07-19 Nuevos compuestos.
BR0211472-0A BR0211472A (pt) 2001-07-25 2002-07-19 Novos compostos
NZ530751A NZ530751A (en) 2001-07-25 2002-07-19 Novel thiophene carboxamide compounds and their use as pharmaceuticals useful in the inhibition of IKK2 activity
CA002454702A CA2454702A1 (en) 2001-07-25 2002-07-19 Novel compounds
AT02756047T ATE353327T1 (de) 2001-07-25 2002-07-19 Thiophenverbindungen als arzneimittel
CNA028152514A CN1538968A (zh) 2001-07-25 2002-07-19 新型化合物
DE60218048T DE60218048T2 (de) 2001-07-25 2002-07-19 Thiophenverbindungen als arzneimittel
ES02756047T ES2280559T3 (es) 2001-07-25 2002-07-19 Compuestos tiofenilicos como medicamentos.
ZA200400494A ZA200400494B (en) 2001-07-25 2004-01-22 Novel compounds.
NO20040314A NO20040314L (no) 2001-07-25 2004-01-23 Nye forbindelser
JP2009291103A JP2010111683A (ja) 2001-07-25 2009-12-22 新規化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0102617A SE0102617D0 (sv) 2001-07-25 2001-07-25 Novel compounds

Publications (1)

Publication Number Publication Date
SE0102617D0 true SE0102617D0 (sv) 2001-07-25

Family

ID=20284945

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0102617A SE0102617D0 (sv) 2001-07-25 2001-07-25 Novel compounds

Country Status (17)

Country Link
US (1) US7098240B2 (sv)
EP (1) EP1421079B1 (sv)
JP (2) JP2004536869A (sv)
KR (1) KR20040018521A (sv)
CN (1) CN1538968A (sv)
AT (1) ATE353327T1 (sv)
BR (1) BR0211472A (sv)
CA (1) CA2454702A1 (sv)
DE (1) DE60218048T2 (sv)
ES (1) ES2280559T3 (sv)
IL (1) IL160023A0 (sv)
MX (1) MXPA04000755A (sv)
NO (1) NO20040314L (sv)
NZ (1) NZ530751A (sv)
SE (1) SE0102617D0 (sv)
WO (1) WO2003010163A1 (sv)
ZA (1) ZA200400494B (sv)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0003154D0 (en) * 2000-02-12 2000-04-05 Astrazeneca Uk Ltd Novel compounds
EP1401825B1 (en) * 2001-06-11 2009-08-05 Virochem Pharma Inc. Thiophene derivatives as antiviral agents for flavivirus infection
SE0102616D0 (sv) * 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
ES2315430T3 (es) * 2001-10-04 2009-04-01 Smithkline Beecham Corporation Inhibidores de nf-kb.
AU2003249683A1 (en) * 2002-06-06 2003-12-22 Smithkline Beecham Corporation Nf-:b inhibitors
DE60332482D1 (de) 2002-12-10 2010-06-17 Virochem Pharma Inc Verbindungen und methoden zum behandeln oder vorbeugen von flavivirus infektionen
SE0300092D0 (sv) 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300091D0 (sv) * 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
CA2536964A1 (en) * 2003-04-25 2004-11-11 Ortho-Mcneil Pharmaceutical, Inc. C-fms kinase inhibitors
US7427683B2 (en) * 2003-04-25 2008-09-23 Ortho-Mcneil Pharmaceutical, Inc. c-fms kinase inhibitors
US20050113566A1 (en) * 2003-04-25 2005-05-26 Player Mark R. Inhibitors of C-FMS kinase
US7790724B2 (en) 2003-04-25 2010-09-07 Janssen Pharmaceutica N.V. c-fms kinase inhibitors
EP1493739A1 (fr) * 2003-07-03 2005-01-05 Warner-Lambert Company LLC Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
US20050085531A1 (en) * 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
MXPA06007692A (es) * 2004-01-05 2007-01-26 Astrazeneca Ab Heterociclos sustituidos y usos de los mismos.
PE20060373A1 (es) 2004-06-24 2006-04-29 Smithkline Beecham Corp Derivados 3-piperidinil-7-carboxamida-indazol como inhibidores de la actividad cinasa de ikk2
PE20060748A1 (es) 2004-09-21 2006-10-01 Smithkline Beecham Corp Derivados de indolcarboxamida como inhibidores de quinasa ikk2
AU2006246227B2 (en) * 2005-05-13 2011-04-28 Virochem Pharma Inc. Compounds and methods for the treatment or prevention of flavivirus infections
JP5059756B2 (ja) 2005-06-30 2012-10-31 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 化合物
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
WO2008058393A1 (en) * 2006-11-15 2008-05-22 Virochem Pharma Inc. Thiophene analogues for the treatment or prevention of flavivirus infections
KR20090109551A (ko) * 2007-01-15 2009-10-20 산텐 세이야꾸 가부시키가이샤 ＩκＢ 키나아제 β 저해 활성을 갖는 신규 인돌 유도체
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
KR20190026056A (ko) 2008-04-21 2019-03-12 오토노미, 인코포레이티드 귀 질환 및 병태를 치료하기 위한 귀 조제물
US8445529B2 (en) * 2008-07-14 2013-05-21 Santen Pharmaceutical Co., Ltd. Indole derivative having, carbamoyl group, ureido group and substituted oxy group
KR20110044767A (ko) * 2008-08-25 2011-04-29 산텐 세이야꾸 가부시키가이샤 우레이도기, 아미노카르보닐기 및 치환기를 가져도 좋은 2환식기를 치환기로서 갖는 신규 피롤 유도체
US8354539B2 (en) 2009-03-10 2013-01-15 Glaxo Group Limited Indole derivatives as IKK2 inhibitors
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
GB201016912D0 (en) 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
GB201021979D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab New compound
EP2520292A1 (en) 2011-05-06 2012-11-07 Helmholtz-Zentrum für Infektionsforschung GmbH Use of spirangiens for the treatment or prevention of IL-8 or IL-6 mediated disorders
CA3029281A1 (en) 2016-06-29 2018-01-04 Otonomy, Inc. Triglyceride otic formulations and uses thereof
CN107739370B (zh) * 2017-10-26 2021-03-30 中国药科大学 吡咯酮类brd4蛋白抑制剂的制备方法以及用途

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GB1468012A (en) 1973-08-09 1977-03-23 Beecham Group Ltd 2-amino-3-carboxy-thiophene derivatives
DE3529247A1 (de) 1985-05-17 1986-11-20 Bayer Ag, 5090 Leverkusen Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung
US6417202B1 (en) 1996-07-11 2002-07-09 Pfizer Inc. Pyridylpyrrole compounds useful as interleukin-and TNF antagonists
PT853083E (pt) 1997-01-06 2001-12-28 Pfizer Composto de piridilfurano e piridiltiofeno e sua utilizacao farmaceutica
US6809088B2 (en) * 1997-03-24 2004-10-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them
US6037340A (en) 1997-05-28 2000-03-14 Cadus Pharmaceutical Corporation Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds
DE19744026A1 (de) 1997-10-06 1999-04-08 Hoechst Marion Roussel De Gmbh Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln
WO1999046244A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
HN2000000051A (es) * 1999-05-19 2001-02-02 Pfizer Prod Inc Derivados heterociclicos utiles como agentes anticancerosos
GB2361236B (en) * 2000-03-29 2002-04-24 Cyclacel Ltd Pyrimidines useful against proliferative disorders
US6414013B1 (en) 2000-06-19 2002-07-02 Pharmacia & Upjohn S.P.A. Thiophene compounds, process for preparing the same, and pharmaceutical compositions containing the same background of the invention
AU2002211663A1 (en) 2000-10-12 2002-04-22 Smith Kline Beecham Corporation Nf-$g(k)b inhibitors

Also Published As

Publication number Publication date
BR0211472A (pt) 2004-11-09
IL160023A0 (en) 2004-06-20
US20040235821A1 (en) 2004-11-25
DE60218048D1 (de) 2007-03-22
EP1421079A1 (en) 2004-05-26
MXPA04000755A (es) 2004-04-20
WO2003010163A1 (en) 2003-02-06
EP1421079B1 (en) 2007-02-07
CN1538968A (zh) 2004-10-20
NO20040314L (no) 2004-03-25
ATE353327T1 (de) 2007-02-15
JP2010111683A (ja) 2010-05-20
CA2454702A1 (en) 2003-02-06
KR20040018521A (ko) 2004-03-03
JP2004536869A (ja) 2004-12-09
NZ530751A (en) 2005-09-30
US7098240B2 (en) 2006-08-29
DE60218048T2 (de) 2007-08-09
ZA200400494B (en) 2005-04-22
ES2280559T3 (es) 2007-09-16

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