PT781095E - Celulas contendo receptores chamariz cd4 e moleculas e metodos com elas relacionados - Google Patents

Celulas contendo receptores chamariz cd4 e moleculas e metodos com elas relacionados

Info

Publication number: PT781095E
Authority: PT; Portugal
Prior art keywords: receptors; chamariz; molecules; cells containing; related methods
Prior art date: 1994-08-02

Application number

PT95928152T

Other languages

English (en)

Inventor

Charles Romeo

Brian Seed

Waldemar Kolanus

Babak Banapour

Original Assignee

Gen Hospital Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-02

Filing date

1995-07-26

Publication date

2003-06-30

1994-08-02 Priority claimed from US08/284,391 external-priority patent/US5851828A/en

1995-02-24 Priority claimed from US08/394,388 external-priority patent/US6753162B1/en

1995-07-26 Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp

2003-06-30 Publication of PT781095E publication Critical patent/PT781095E/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Cell Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Virology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Mycology (AREA)
Toxicology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

PT95928152T 1994-08-02 1995-07-26 Celulas contendo receptores chamariz cd4 e moleculas e metodos com elas relacionados PT781095E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/284,391 US5851828A (en)	1991-03-07	1994-08-02	Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
US08/394,388 US6753162B1 (en)	1991-03-07	1995-02-24	Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells

Publications (1)

Publication Number	Publication Date
PT781095E true PT781095E (pt)	2003-06-30

Family

ID=26962581

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95928152T PT781095E (pt)	1994-08-02	1995-07-26	Celulas contendo receptores chamariz cd4 e moleculas e metodos com elas relacionados

Country Status (22)

Country	Link
EP (1)	EP0781095B1 (pt)
JP (1)	JP3832856B2 (pt)
KR (1)	KR100384249B1 (pt)
CN (1)	CN1142941C (pt)
AT (1)	ATE234011T1 (pt)
AU (1)	AU697489B2 (pt)
CA (1)	CA2195653C (pt)
CZ (1)	CZ293943B6 (pt)
DE (1)	DE69529910T2 (pt)
DK (1)	DK0781095T3 (pt)
ES (1)	ES2191058T3 (pt)
FI (1)	FI119868B (pt)
HK (1)	HK1002545A1 (pt)
HU (1)	HU221603B (pt)
IL (1)	IL114778A (pt)
MX (1)	MX9700800A (pt)
NO (1)	NO325081B1 (pt)
NZ (1)	NZ291017A (pt)
PL (1)	PL181085B1 (pt)
PT (1)	PT781095E (pt)
UA (1)	UA45349C2 (pt)
WO (1)	WO1996003883A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6544523B1 (en)	1996-11-13	2003-04-08	Chiron Corporation	Mutant forms of Fas ligand and uses thereof
IL142164A0 (en) *	1998-09-23	2002-03-10	Zymogenetics Inc	Cytokine receptor zalpha11
RU2746486C2 (ru) *	2015-03-13	2021-04-14	Юниверсити Оф Мэрилэнд, Балтимор	Универсальный антителоопосредованный биосенсор
SG11201800872QA (en)	2015-08-05	2018-03-28	Yoo Young Pharm Co Ltd	Chimeric antigen receptor, and t cells in which chimeric antigen receptor is expressed
WO2017053556A1 (en) *	2015-09-22	2017-03-30	The Trustees Of The University Of Pennsylvania	Method of redirecting t cells to treat hiv infection
WO2021061862A1 (en)	2019-09-24	2021-04-01	The Regents Of The University Of California	Notch receptors with hinge domain
US20220348628A1 (en) *	2019-09-24	2022-11-03	The Regents Of The University Of California	Novel receptors having a fibronectin repeat for ligand-dependent transcriptional regulation
WO2021061863A1 (en) *	2019-09-24	2021-04-01	The Regents Of The University Of California	Notch receptors with minimal linker
WO2021061856A1 (en) *	2019-09-24	2021-04-01	The Regents Of The University Of California	Receptors with heterologous transmembrane domain
CN112176037A (zh) *	2020-09-24	2021-01-05	深圳普瑞金生物药业有限公司	检测car-t细胞目的基因拷贝数的方法、引物对、探针及试剂盒
EP4112639A1 (en) *	2021-07-02	2023-01-04	Universitat de Barcelona	Car t/nk-cells for use in the treatment of invasive fungal infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6463394A (en) *	1987-09-04	1989-03-09	Kyowa Hakko Kogyo Kk	Novel chimera polypeptide
PT89484B (pt) *	1988-01-22	1994-03-31	Gen Hospital Corp	Genes clonados codificadores de proteinas de fusao ig-cd4 e sua utilizacao
IL101147A (en) *	1991-03-07	2004-06-20	Gen Hospital Corp	Change of direction of cellular immunity by chimera receptors
US5851828A (en) *	1991-03-07	1998-12-22	The General Hospital Corporation	Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells

1995
- 1995-07-26 PT PT95928152T patent/PT781095E/pt unknown
- 1995-07-26 DE DE69529910T patent/DE69529910T2/de not_active Expired - Lifetime
- 1995-07-26 WO PCT/US1995/009468 patent/WO1996003883A1/en active IP Right Grant
- 1995-07-26 ES ES95928152T patent/ES2191058T3/es not_active Expired - Lifetime
- 1995-07-26 EP EP95928152A patent/EP0781095B1/en not_active Expired - Lifetime
- 1995-07-26 AT AT95928152T patent/ATE234011T1/de active
- 1995-07-26 HU HU9700303A patent/HU221603B/hu unknown
- 1995-07-26 KR KR1019970700681A patent/KR100384249B1/ko not_active IP Right Cessation
- 1995-07-26 JP JP50660096A patent/JP3832856B2/ja not_active Expired - Lifetime
- 1995-07-26 MX MX9700800A patent/MX9700800A/es active IP Right Grant
- 1995-07-26 CA CA2195653A patent/CA2195653C/en not_active Expired - Lifetime
- 1995-07-26 AU AU32014/95A patent/AU697489B2/en not_active Expired
- 1995-07-26 CZ CZ1997264A patent/CZ293943B6/cs not_active IP Right Cessation
- 1995-07-26 CN CNB951951831A patent/CN1142941C/zh not_active Expired - Lifetime
- 1995-07-26 DK DK95928152T patent/DK0781095T3/da active
- 1995-07-26 NZ NZ291017A patent/NZ291017A/en not_active IP Right Cessation
- 1995-07-26 UA UA97020482A patent/UA45349C2/uk unknown
- 1995-07-26 PL PL95318443A patent/PL181085B1/pl unknown
- 1995-07-30 IL IL114778A patent/IL114778A/en not_active IP Right Cessation
1997
- 1997-01-31 NO NO19970440A patent/NO325081B1/no not_active IP Right Cessation
- 1997-01-31 FI FI970428A patent/FI119868B/fi not_active IP Right Cessation
1998
- 1998-03-03 HK HK98101624A patent/HK1002545A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUT77253A (hu)	1998-03-02
HK1002545A1 (en)	1998-09-04
EP0781095B1 (en)	2003-03-12
KR970704357A (ko)	1997-09-06
ATE234011T1 (de)	2003-03-15
AU3201495A (en)	1996-03-04
PL181085B1 (pl)	2001-05-31
CN1158552A (zh)	1997-09-03
UA45349C2 (uk)	2002-04-15
CN1142941C (zh)	2004-03-24
CA2195653C (en)	2010-04-27
NO970440L (no)	1997-03-26
ES2191058T3 (es)	2003-09-01
JPH10503932A (ja)	1998-04-14
FI970428A0 (fi)	1997-01-31
NZ291017A (en)	1998-05-27
PL318443A1 (en)	1997-06-09
FI119868B (fi)	2009-04-30
WO1996003883A1 (en)	1996-02-15
DE69529910D1 (de)	2003-04-17
CZ293943B6 (cs)	2004-08-18
MX9700800A (es)	1997-11-29
NO325081B1 (no)	2008-01-28
JP3832856B2 (ja)	2006-10-11
DE69529910T2 (de)	2003-12-18
HU221603B (hu)	2002-11-28
CA2195653A1 (en)	1996-02-15
EP0781095A1 (en)	1997-07-02
DK0781095T3 (da)	2003-06-23
FI970428A (fi)	1997-03-26
IL114778A (en)	2008-08-07
AU697489B2 (en)	1998-10-08
CZ26497A3 (en)	1997-10-15
EP0781095A4 (en)	1999-03-03
KR100384249B1 (ko)	2003-08-30
IL114778A0 (en)	1995-11-27
NO970440D0 (no)	1997-01-31

Publication	Publication Date	Title
FI963150A0 (fi)	1996-08-12	HIV-infektoitujen solujen kohdistettu sytolyysi kimeeristä CD4-reseptoria sisältävillä soluille
PT781095E (pt)	2003-06-30	Celulas contendo receptores chamariz cd4 e moleculas e metodos com elas relacionados
EP0575546A4 (en)	1996-04-03	Prad1 cyclin and its cdna
EP1392835A4 (en)	2006-04-19	EPRESSION VECTOR FOR ANIMAL CELLS
ATE245030T1 (de)	2003-08-15	Antigen-besierende heteropolymere zur behandlung von autoimmunkrankheiten mittels diesen
BR1100650A (pt)	2000-08-08	Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia
NO860421L (no)	1986-02-06	Sammensmeltet gen som koder for et hybridprotein.
ES2010727A6 (es)	1989-12-01	Metodo para producir lineas celulares que producen anticuerpos monoclonales reactivos frente a determinantes antigenicos de gp110 o de p25 de hiv.
DE69535501D1 (de)	2007-07-05	Identifikation, reinigung und verwendungen von leczymen und karbohydratliganden
DE69637599D1 (de)	2008-08-21	Rezeptoren für das humane Interleukin-12
KR880009991A (ko)	1988-10-06	항혈액응고작용을 갖는 폴리펩티드
DK0629238T3 (da)	2000-12-18	Autotaxin:Motilitetsstimulerende protein, som er nyttigt til cancerdiagnose og terapi
DE69631624D1 (de)	2004-04-01	Antikörper gegen menschliches restrictin
ATE309371T1 (de)	2005-11-15	Protein mit dnase-aktivität
DE69227618D1 (de)	1998-12-24	Die verwendung des leukozyten adhäsionsmolekül-1- aus endothelzellen und antikörper dagegen in der behandlung von asthma
NZ330034A (en)	2000-08-25	Method of treating HIV in mammals by administering cells bearing CD4 decoy receptors
RU97103190A (ru)	1999-04-20	Способы создания клеток, несущих cd4-рецепторные ловушки и родственные молекулы
CO4410253A1 (es)	1997-01-09	Citolisis dirigida de celulas infectadas de hiv mediante celulas que portan el receptor cd4 quimerico
NO922447L (no)	1992-08-19	Hybridmolekyler med translokasjonsregion og cellebindenderegion
MY143222A (en)	2011-03-31	Expression vector for animal cell