PT2427454E - Compostos fenoximetilo heterocíclicos - Google Patents
Compostos fenoximetilo heterocíclicosInfo
- Publication number
- PT2427454E PT2427454E PT97962179T PT09796217T PT2427454E PT 2427454 E PT2427454 E PT 2427454E PT 97962179 T PT97962179 T PT 97962179T PT 09796217 T PT09796217 T PT 09796217T PT 2427454 E PT2427454 E PT 2427454E
- Authority
- PT
- Portugal
- Prior art keywords
- heterocyclic compounds
- phenoxymethyl
- phenoxymethyl heterocyclic
- compounds
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Addiction (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17641309P | 2009-05-07 | 2009-05-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2427454E true PT2427454E (pt) | 2013-06-20 |
Family
ID=41549054
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT131503229T PT2617420E (pt) | 2009-05-07 | 2009-12-18 | Compostos heterocíclicos de fenoximetil |
PT97962179T PT2427454E (pt) | 2009-05-07 | 2009-12-18 | Compostos fenoximetilo heterocíclicos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT131503229T PT2617420E (pt) | 2009-05-07 | 2009-12-18 | Compostos heterocíclicos de fenoximetil |
Country Status (33)
Country | Link |
---|---|
US (3) | US8343973B2 (pt) |
EP (3) | EP2617420B1 (pt) |
JP (2) | JP5628902B2 (pt) |
KR (1) | KR101662699B1 (pt) |
CN (2) | CN102459242B (pt) |
AU (1) | AU2009345802B2 (pt) |
BR (1) | BRPI0924617A8 (pt) |
CA (1) | CA2761032A1 (pt) |
CL (1) | CL2011002792A1 (pt) |
CO (1) | CO6460744A2 (pt) |
CR (1) | CR20110648A (pt) |
DK (2) | DK2617420T3 (pt) |
EC (1) | ECSP11011479A (pt) |
ES (2) | ES2554788T3 (pt) |
HK (2) | HK1167402A1 (pt) |
HR (2) | HRP20130482T1 (pt) |
HU (1) | HUE026238T2 (pt) |
IL (2) | IL216149A (pt) |
ME (1) | ME02375B (pt) |
MX (1) | MX2011011755A (pt) |
MY (1) | MY183910A (pt) |
NZ (1) | NZ596753A (pt) |
PE (1) | PE20120900A1 (pt) |
PH (1) | PH12013501321A1 (pt) |
PL (2) | PL2617420T3 (pt) |
PT (2) | PT2617420E (pt) |
RS (2) | RS54529B1 (pt) |
RU (1) | RU2531274C2 (pt) |
SG (1) | SG175900A1 (pt) |
SI (2) | SI2427454T1 (pt) |
SM (2) | SMT201300070B (pt) |
WO (1) | WO2010128995A1 (pt) |
ZA (1) | ZA201108920B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009158393A1 (en) | 2008-06-25 | 2009-12-30 | Envivo Pharmaceuticals, Inc. | 1, 2 disubstituted heterocyclic compounds |
PT2617420E (pt) | 2009-05-07 | 2015-12-18 | Forum Pharmaceuticals Inc | Compostos heterocíclicos de fenoximetil |
CN103476757A (zh) | 2011-02-18 | 2013-12-25 | 阿勒根公司 | 作为磷酸二酯酶10(pde10a)的抑制剂的取代的6,7-二烷氧基-3-异喹啉醇衍生物 |
MX2014015156A (es) | 2012-06-12 | 2015-08-06 | Abbvie Inc | Derivados de piridinona y piridazinona. |
WO2014071044A1 (en) | 2012-11-01 | 2014-05-08 | Allergan, Inc. | Substituted 6,7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
ES2480341B1 (es) | 2013-01-24 | 2015-01-22 | Palobiofarma S.L | Nuevos derivados de pirimidina como inhibidores de la fosfodiesterasa 10 (PDE-10) |
TW201512201A (zh) * | 2013-03-14 | 2015-04-01 | Forum Pharmaceuticals Inc | 化合物的多晶型及鹽類 |
TWI634114B (zh) * | 2013-05-08 | 2018-09-01 | 永恒生物科技公司 | 作為激酶抑制劑之呋喃酮化合物 |
WO2015006689A1 (en) | 2013-07-12 | 2015-01-15 | University Of South Alabama | Treatment and diagnosis of cancer and precancerous conditions using pde10a inhibitors and methods to measure pde10a expression |
US9200016B2 (en) | 2013-12-05 | 2015-12-01 | Allergan, Inc. | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) |
EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | PYRROLE AND PYRAZOLE COMPOUNDS AND METHODS OF USE THERE |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1233962E (pt) * | 1999-11-05 | 2006-07-31 | Sod Conseils Rech Applic | Compostos heterociclicos e a sua utilizacao como medicamentos |
US20030032579A1 (en) * | 2001-04-20 | 2003-02-13 | Pfizer Inc. | Therapeutic use of selective PDE10 inhibitors |
EP1541149A1 (en) | 2002-06-26 | 2005-06-15 | Kyowa Hakko Kogyo Co., Ltd. | Phosphodiesterase inhibitor |
CA2592986C (en) | 2005-01-07 | 2011-02-15 | Pfizer Products Inc. | Heteroaromatic quinoline compounds |
NL2000397C2 (nl) * | 2006-01-05 | 2007-10-30 | Pfizer Prod Inc | Bicyclische heteroarylverbindingen als PDE10 inhibitoren. |
EP1845098A1 (en) * | 2006-03-29 | 2007-10-17 | Ferrer Internacional, S.A. | Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands |
CA2650976A1 (en) * | 2006-05-02 | 2007-11-15 | Pfizer Products Inc. | Bicyclic heteroaryl compounds as pde10 inhibitors |
WO2008033455A2 (en) | 2006-09-13 | 2008-03-20 | The Institutes For Pharmaceutical Discovery, Llc | Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors |
FR2928924B1 (fr) * | 2008-03-21 | 2010-04-23 | Sanofi Aventis | Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique |
WO2009158393A1 (en) * | 2008-06-25 | 2009-12-30 | Envivo Pharmaceuticals, Inc. | 1, 2 disubstituted heterocyclic compounds |
PT2617420E (pt) | 2009-05-07 | 2015-12-18 | Forum Pharmaceuticals Inc | Compostos heterocíclicos de fenoximetil |
ES2730086T3 (es) * | 2009-09-03 | 2019-11-08 | Allergan Inc | Compuestos como moduladores de tirosina cinasa |
RU2016124136A (ru) * | 2010-08-18 | 2018-12-03 | СЭМЬЮМЕД, ЭлЭлСи | Дикетоны и гидроксикетоны в качестве активатора сигнального пути катенина |
-
2009
- 2009-12-18 PT PT131503229T patent/PT2617420E/pt unknown
- 2009-12-18 SI SI200930609T patent/SI2427454T1/sl unknown
- 2009-12-18 RS RS20150803A patent/RS54529B1/en unknown
- 2009-12-18 SG SG2011081437A patent/SG175900A1/en unknown
- 2009-12-18 KR KR1020117028223A patent/KR101662699B1/ko active IP Right Grant
- 2009-12-18 RU RU2011149637/04A patent/RU2531274C2/ru not_active IP Right Cessation
- 2009-12-18 AU AU2009345802A patent/AU2009345802B2/en not_active Ceased
- 2009-12-18 PT PT97962179T patent/PT2427454E/pt unknown
- 2009-12-18 EP EP13150322.9A patent/EP2617420B1/en active Active
- 2009-12-18 CN CN200980159735.6A patent/CN102459242B/zh not_active Expired - Fee Related
- 2009-12-18 WO PCT/US2009/068644 patent/WO2010128995A1/en active Application Filing
- 2009-12-18 CN CN201510438849.1A patent/CN105125547A/zh active Pending
- 2009-12-18 ES ES13150322.9T patent/ES2554788T3/es active Active
- 2009-12-18 DK DK13150322.9T patent/DK2617420T3/da active
- 2009-12-18 ME MEP-2015-210A patent/ME02375B/me unknown
- 2009-12-18 PL PL13150322T patent/PL2617420T3/pl unknown
- 2009-12-18 PE PE2011001918A patent/PE20120900A1/es not_active Application Discontinuation
- 2009-12-18 SI SI200931314T patent/SI2617420T1/sl unknown
- 2009-12-18 MY MYPI2011005358A patent/MY183910A/en unknown
- 2009-12-18 PL PL09796217T patent/PL2427454T3/pl unknown
- 2009-12-18 EP EP15184753.0A patent/EP3020716A1/en not_active Withdrawn
- 2009-12-18 DK DK09796217.9T patent/DK2427454T3/da active
- 2009-12-18 JP JP2012509778A patent/JP5628902B2/ja not_active Expired - Fee Related
- 2009-12-18 US US12/642,026 patent/US8343973B2/en not_active Expired - Fee Related
- 2009-12-18 MX MX2011011755A patent/MX2011011755A/es active IP Right Grant
- 2009-12-18 HU HUE13150322A patent/HUE026238T2/en unknown
- 2009-12-18 BR BRPI0924617A patent/BRPI0924617A8/pt not_active IP Right Cessation
- 2009-12-18 CA CA2761032A patent/CA2761032A1/en not_active Abandoned
- 2009-12-18 NZ NZ596753A patent/NZ596753A/xx not_active IP Right Cessation
- 2009-12-18 EP EP09796217A patent/EP2427454B1/en active Active
- 2009-12-18 RS RS20130218A patent/RS52838B/en unknown
- 2009-12-18 ES ES09796217T patent/ES2409404T3/es active Active
-
2011
- 2011-11-03 IL IL216149A patent/IL216149A/en not_active IP Right Cessation
- 2011-11-07 CL CL2011002792A patent/CL2011002792A1/es unknown
- 2011-11-11 CO CO11153626A patent/CO6460744A2/es active IP Right Grant
- 2011-11-24 EC EC2011011479A patent/ECSP11011479A/es unknown
- 2011-12-05 ZA ZA2011/08920A patent/ZA201108920B/en unknown
- 2011-12-05 CR CR20110648A patent/CR20110648A/es unknown
-
2012
- 2012-08-21 HK HK12108181.8A patent/HK1167402A1/xx not_active IP Right Cessation
- 2012-12-20 US US13/722,595 patent/US8946222B2/en not_active Expired - Fee Related
-
2013
- 2013-05-31 HR HRP20130482AT patent/HRP20130482T1/hr unknown
- 2013-06-20 SM SM201300070T patent/SMT201300070B/xx unknown
- 2013-06-20 PH PH12013501321A patent/PH12013501321A1/en unknown
-
2014
- 2014-01-06 HK HK14100085.0A patent/HK1186981A1/xx not_active IP Right Cessation
- 2014-10-02 JP JP2014204220A patent/JP5943053B2/ja not_active Expired - Fee Related
- 2014-12-09 US US14/564,507 patent/US20150322069A1/en not_active Abandoned
-
2015
- 2015-11-25 HR HRP20151273TT patent/HRP20151273T1/hr unknown
-
2016
- 2016-02-04 SM SM201600031T patent/SMT201600031B/it unknown
- 2016-02-10 IL IL244059A patent/IL244059A0/en unknown
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