PL411223A1 - Sposób bezinwazyjnego pomiaru glukozy we krwi i układ optoelektroniczny do bezinwazyjnego pomiaru glukozy we krwi - Google Patents
Sposób bezinwazyjnego pomiaru glukozy we krwi i układ optoelektroniczny do bezinwazyjnego pomiaru glukozy we krwiInfo
- Publication number
- PL411223A1 PL411223A1 PL411223A PL41122315A PL411223A1 PL 411223 A1 PL411223 A1 PL 411223A1 PL 411223 A PL411223 A PL 411223A PL 41122315 A PL41122315 A PL 41122315A PL 411223 A1 PL411223 A1 PL 411223A1
- Authority
- PL
- Poland
- Prior art keywords
- raman
- blood
- glucose
- radiation
- synchronous detection
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 4
- 210000004369 blood Anatomy 0.000 title abstract 4
- 239000008280 blood Substances 0.000 title abstract 4
- 239000008103 glucose Substances 0.000 title abstract 4
- 238000005259 measurement Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000005693 optoelectronics Effects 0.000 title abstract 2
- 238000001069 Raman spectroscopy Methods 0.000 abstract 4
- 230000005855 radiation Effects 0.000 abstract 4
- 238000001514 detection method Methods 0.000 abstract 3
- 230000001360 synchronised effect Effects 0.000 abstract 3
- 238000001237 Raman spectrum Methods 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 238000003841 Raman measurement Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Sposób i układ do bezinwazyjnego pomiaru glukozy we krwi polega na wykorzystaniu widm Ramana oraz pomiarach modulowanej pulsem zawartości czerwonych ciałek krwi w oświetlanych tkankach i zastosowaniu detekcji synchronicznej, redukującej wpływ szumów układu pomiarowego i różnic w tkankach między osobnikami. Układ optoelektroniczny zawiera laser promieniowania pobudzającego (LR), którego promieniowanie po przejściu przez sondę Ramana (SR) oświetla badaną tkankę (TK), a promieniowanie rozproszenia ramanowskiego jest gromadzone przez sondę Ramana (SR) i rejestrowane kamerą (KR) po przejściu przez spektrometr (SP). Jednocześnie mierzy się pulsoksymetrem (PO) puls w obszarze zbliżonym objętościowo, co rejestrowane promieniowanie rozproszenia ramanowskiego. Dla obydwu sygnałów stosuje się detekcję synchroniczną, realizowaną przez komputer sterujący (KS), w którym zaimplementowany jest układ mnożący i filtr dolnoprzepustowy. Detekcja synchroniczna pozwala wyodrębnić w widmie Ramana sygnał proporcjonalny do stężenia glukozy we krwi, redukując szumy układu pomiarowego i efekty pochodzące od różnic w składzie oświetlanych tkanek w wyniku zmienności osobniczej.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL411223A PL235367B1 (pl) | 2015-02-10 | 2015-02-10 | Sposób bezinwazyjnego pomiaru glukozy we krwi i układ optoelektroniczny do bezinwazyjnego pomiaru glukozy we krwi |
| EP15460074.6A EP3056141A1 (en) | 2015-02-10 | 2015-09-23 | A method of non-invasive measurement of blood glucose and optoelectronic system to non-invasive measurement of blood glucose |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL411223A PL235367B1 (pl) | 2015-02-10 | 2015-02-10 | Sposób bezinwazyjnego pomiaru glukozy we krwi i układ optoelektroniczny do bezinwazyjnego pomiaru glukozy we krwi |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL411223A1 true PL411223A1 (pl) | 2016-08-16 |
| PL235367B1 PL235367B1 (pl) | 2020-06-29 |
Family
ID=54705149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL411223A PL235367B1 (pl) | 2015-02-10 | 2015-02-10 | Sposób bezinwazyjnego pomiaru glukozy we krwi i układ optoelektroniczny do bezinwazyjnego pomiaru glukozy we krwi |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP3056141A1 (pl) |
| PL (1) | PL235367B1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11026604B2 (en) | 2017-07-13 | 2021-06-08 | Cercacor Laboratories, Inc. | Medical monitoring device for harmonizing physiological measurements |
| CN109171694B (zh) * | 2018-07-23 | 2021-04-06 | 北京大学深圳研究生院 | 一种基于脉搏信号的糖尿病病情评估方法及系统 |
| US11986289B2 (en) | 2018-11-27 | 2024-05-21 | Willow Laboratories, Inc. | Assembly for medical monitoring device with multiple physiological sensors |
| US20220022784A1 (en) * | 2018-12-14 | 2022-01-27 | Ecole Polytechnique Federale De Lausanne (Epfl) | Non-invasive Glucose Sensor |
| CN111227844B (zh) * | 2020-03-27 | 2022-05-20 | 宁波大学 | 一种基于拉曼散射光谱的无创血糖检测装置及检测方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5737439A (en) * | 1996-10-29 | 1998-04-07 | Smarttouch, Llc. | Anti-fraud biometric scanner that accurately detects blood flow |
| DE69836979T2 (de) | 1997-11-12 | 2007-11-08 | Lightouch Medical, Inc. | Verfahren zur nicht invasiven analytenmessung |
| WO2005109700A1 (en) * | 2004-05-04 | 2005-11-17 | Stheno Corporation | A double reference lock-in detector |
| DE102005024578A1 (de) * | 2005-05-25 | 2006-11-30 | Raumedic Ag | Sonde zur Messung des Sauerstoffgehaltes in biologischem Gewebe sowie Katheter mit einer derartigen Sonde |
| PL1912058T3 (pl) * | 2006-10-14 | 2011-05-31 | Hoffmann La Roche | Sposób i urządzenie do wykrywania i oceny sygnałów optycznych |
| US8412293B2 (en) * | 2007-07-16 | 2013-04-02 | Optiscan Biomedical Corporation | Systems and methods for determining physiological parameters using measured analyte values |
| US20130267799A1 (en) * | 2012-04-06 | 2013-10-10 | Hannu Harjunmaa | Noninvasive measurement of analyte concentration using a fiberless transflectance probe |
-
2015
- 2015-02-10 PL PL411223A patent/PL235367B1/pl unknown
- 2015-09-23 EP EP15460074.6A patent/EP3056141A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP3056141A1 (en) | 2016-08-17 |
| PL235367B1 (pl) | 2020-06-29 |
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