Nothing Special   »   [go: up one dir, main page]

PL3818078T3 - Metody produkcji białek rekombinowanych - Google Patents

Metody produkcji białek rekombinowanych

Info

Publication number
PL3818078T3
PL3818078T3 PL19745845.8T PL19745845T PL3818078T3 PL 3818078 T3 PL3818078 T3 PL 3818078T3 PL 19745845 T PL19745845 T PL 19745845T PL 3818078 T3 PL3818078 T3 PL 3818078T3
Authority
PL
Poland
Prior art keywords
methods
recombinant proteins
producing recombinant
producing
proteins
Prior art date
Application number
PL19745845.8T
Other languages
English (en)
Inventor
JianLin XU
Andrew YONGKY
Jun Tian
Michael C. BORYS
Zhengjian Li
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of PL3818078T3 publication Critical patent/PL3818078T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/34Sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL19745845.8T 2018-07-03 2019-07-02 Metody produkcji białek rekombinowanych PL3818078T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862693606P 2018-07-03 2018-07-03
PCT/US2019/040298 WO2020010080A1 (en) 2018-07-03 2019-07-02 Methods of producing recombinant proteins

Publications (1)

Publication Number Publication Date
PL3818078T3 true PL3818078T3 (pl) 2024-04-29

Family

ID=67470657

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19745845.8T PL3818078T3 (pl) 2018-07-03 2019-07-02 Metody produkcji białek rekombinowanych

Country Status (23)

Country Link
US (1) US20210253996A1 (pl)
EP (2) EP3818078B1 (pl)
JP (2) JP7419273B2 (pl)
KR (1) KR20210027427A (pl)
CN (1) CN112839954A (pl)
AU (1) AU2019299358A1 (pl)
BR (1) BR112020025623A2 (pl)
CA (1) CA3104684A1 (pl)
DK (1) DK3818078T3 (pl)
EA (1) EA202092904A1 (pl)
ES (1) ES2976708T3 (pl)
FI (1) FI3818078T3 (pl)
HR (1) HRP20240584T1 (pl)
HU (1) HUE066560T2 (pl)
IL (1) IL279782A (pl)
LT (1) LT3818078T (pl)
MX (1) MX2020013633A (pl)
PL (1) PL3818078T3 (pl)
PT (1) PT3818078T (pl)
RS (1) RS65472B1 (pl)
SG (1) SG11202012582QA (pl)
SI (1) SI3818078T1 (pl)
WO (1) WO2020010080A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023242238A1 (en) * 2022-06-15 2023-12-21 UCB Biopharma SRL Cell culture processes
EP4339274A1 (en) 2022-09-13 2024-03-20 Sartorius Stedim Biotech GmbH Method for operating a bioprocess installation for production of a bioproduct

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
US5672347A (en) 1984-07-05 1997-09-30 Genentech, Inc. Tumor necrosis factor antagonists and their use
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
DE68919361T2 (de) 1988-06-21 1995-05-24 Genentech Inc Therapeutische zusammensetzungen für die behandlung von myocard-infarkten.
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
DK0602126T3 (da) 1991-08-14 2003-06-16 Genentech Inc Immunoglobulinvarianter til specifikke FC epsilon-receptorer
CA2140933A1 (en) 1992-08-21 1994-02-22 Paula M. Jardieu Method for treating an lfa-1 mediated disorder
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
DK0733207T3 (da) 1993-12-10 1998-04-20 Genentech Inc Fremgangsmåder til diagnose af allergi og screening af anti-allergi-terapeutika
AP660A (en) 1994-01-18 1998-08-18 Genentech Inc A method of treatment of parasitic infection using IgE antagonists.
EP0749488A1 (en) 1994-03-03 1996-12-27 Genentech, Inc. Anti-il-8 monoclonal antibodies for treatment of inflammatory disorders
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
CA2222231A1 (en) 1995-06-07 1996-12-19 Imclone Systems Incorporated Antibody and antibody fragments for inhibiting the growth of tumors
AU724449B2 (en) 1996-01-23 2000-09-21 Genentech Inc. Anti-CD18 antibodies for use against stroke
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
ATE267257T1 (de) 1996-11-27 2004-06-15 Genentech Inc Humanisierte anti-koerper gegen cd11a
CA2286330C (en) 1997-04-07 2008-06-10 Genentech, Inc. Anti-vegf antibodies
PT1860187E (pt) 1997-05-15 2011-10-04 Genentech Inc Receptor apo-2
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
CN1413220A (zh) 1999-10-29 2003-04-23 杰南技术公司 抗前列腺干细胞抗原(psca)抗体组合物及其应用方法
TWI374935B (en) * 2004-08-27 2012-10-21 Pfizer Ireland Pharmaceuticals Production of α-abeta
EP2532737A3 (en) * 2006-09-13 2013-03-27 Abbott Laboratories Cell culture improvements
SG10201801372YA (en) 2011-02-07 2018-04-27 Cerenis Therapeutics Holding S A Lipoprotein complexes and manufacturing and uses thereof
PT2726600T (pt) * 2011-07-01 2017-04-24 Amgen Inc Cultura celular de mamífero
WO2015186075A1 (en) * 2014-06-03 2015-12-10 Lupin Limited Cell culture process for producing a protein
JP5731726B1 (ja) 2014-06-26 2015-06-10 楽天株式会社 情報処理装置、情報処理方法及び情報処理プログラム

Also Published As

Publication number Publication date
JP2024050590A (ja) 2024-04-10
EA202092904A1 (ru) 2021-04-22
EP3818078A1 (en) 2021-05-12
CN112839954A (zh) 2021-05-25
JP2021529527A (ja) 2021-11-04
CA3104684A1 (en) 2020-01-09
LT3818078T (lt) 2024-04-25
SG11202012582QA (en) 2021-01-28
SI3818078T1 (sl) 2024-05-31
EP3818078B1 (en) 2024-02-28
US20210253996A1 (en) 2021-08-19
EP4368699A3 (en) 2024-09-11
RS65472B1 (sr) 2024-05-31
KR20210027427A (ko) 2021-03-10
MX2020013633A (es) 2021-03-25
DK3818078T3 (da) 2024-05-21
AU2019299358A1 (en) 2021-02-18
ES2976708T3 (es) 2024-08-07
PT3818078T (pt) 2024-04-18
BR112020025623A2 (pt) 2021-03-23
JP7419273B2 (ja) 2024-01-22
EP4368699A2 (en) 2024-05-15
HUE066560T2 (hu) 2024-08-28
IL279782A (en) 2021-03-01
WO2020010080A1 (en) 2020-01-09
FI3818078T3 (fi) 2024-05-14
HRP20240584T1 (hr) 2024-07-19

Similar Documents

Publication Publication Date Title
IL281954A (en) Heterodimeric chimeric proteins
IL288205A (en) Purification of fkpa and its uses for the production of recombinant polypeptides
GB201419109D0 (en) Incorporation of unnatural amino acids into proteins
ZA202006604B (en) Method for selection of high m6p recombinant proteins
IL286745A (en) Continuous production of recombinant proteins
MA53498A (fr) Production de protéines recombinantes
IL276067A (en) Production of glucagon peptides
EP3592800A4 (en) COMPOSITIONS AND METHODS OF PRODUCING HIGHLY SECRETED YIELD OF RECOMBINANT PROTEIN
GB201806072D0 (en) Methods of manufacture
EP3592762A4 (en) COMPOSITIONS AND METHODS OF PRODUCING HIGHLY SECRETED YIELD OF RECOMBINANT PROTEIN
EP3495491A4 (en) PROCESS FOR PRODUCING RECOMBINANT PROTEIN
EP3377633C0 (en) PRODUCTION OF RECOMBINANT PROTEINS
IL284026A (en) Methods for producing heterodimeric antibodies
ZA202101433B (en) An improved process for the preparation of recombinant lectin protein
IL279782A (en) Methods for producing recombinant proteins
IL262544A (en) A method for producing a recombinant protein
HK1255456A1 (zh) 含fc蛋白的表達
GB201805904D0 (en) Methods of Manufacture
EP3532618A4 (en) SIGNAL POLYPEPTIDES FOR IMPROVED PROTEIN SECRETION
SG11202107697UA (en) Method for producing recombinant protein
EP3680343A4 (en) PROCESS FOR INCREASING RECOMBINANT PROTEIN SECRETION
HK1256714A1 (zh) 製備治療性蛋白質的方法
SG11201708751RA (en) Method of producing a recombinant protein
IL256707B (en) A method for the production of recombinant proteins
IL256706B (en) A method for making recombinant proteins