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PL1833799T3 - 3-Fenylo-pirazolowe pochodne jako modulatory 5-HT2A receptora serotoniny użyteczne w leczeniu zaburzeń związanych z tym receptorem - Google Patents

3-Fenylo-pirazolowe pochodne jako modulatory 5-HT2A receptora serotoniny użyteczne w leczeniu zaburzeń związanych z tym receptorem

Info

Publication number
PL1833799T3
PL1833799T3 PL05849546T PL05849546T PL1833799T3 PL 1833799 T3 PL1833799 T3 PL 1833799T3 PL 05849546 T PL05849546 T PL 05849546T PL 05849546 T PL05849546 T PL 05849546T PL 1833799 T3 PL1833799 T3 PL 1833799T3
Authority
PL
Poland
Prior art keywords
modulators
phenyl
treatment
disorders related
serotonin receptor
Prior art date
Application number
PL05849546T
Other languages
English (en)
Inventor
Bradley Teegarden
Yifeng Xiong
Sonja Strah-Pleynet
Honnappa Jayakumar
Peter I Dosa
Konrad Feichtinger
Martin Casper
Juerg Lehmann
Robert M Jones
David J Unett
Jin Sun Karoline Choi
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of PL1833799T3 publication Critical patent/PL1833799T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P9/12—Antihypertensives
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D487/08—Bridged systems
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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PL05849546T 2004-11-19 2005-11-17 3-Fenylo-pirazolowe pochodne jako modulatory 5-HT2A receptora serotoniny użyteczne w leczeniu zaburzeń związanych z tym receptorem PL1833799T3 (pl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US62977404P 2004-11-19 2004-11-19
US64763905P 2005-01-26 2005-01-26
US65838405P 2005-03-02 2005-03-02
US71338405P 2005-09-01 2005-09-01
US73316505P 2005-11-04 2005-11-04
EP05849546A EP1833799B1 (en) 2004-11-19 2005-11-17 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT-2a SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
PCT/US2005/041726 WO2006055734A2 (en) 2004-11-19 2005-11-17 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto

Publications (1)

Publication Number Publication Date
PL1833799T3 true PL1833799T3 (pl) 2009-02-27

Family

ID=36218810

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PL05849546T PL1833799T3 (pl) 2004-11-19 2005-11-17 3-Fenylo-pirazolowe pochodne jako modulatory 5-HT2A receptora serotoniny użyteczne w leczeniu zaburzeń związanych z tym receptorem

Country Status (37)

Country Link
US (6) US20070244086A1 (pl)
EP (2) EP1978019A1 (pl)
JP (1) JP5016494B2 (pl)
KR (2) KR101275380B1 (pl)
CN (3) CN103012378A (pl)
AR (1) AR051675A1 (pl)
AT (1) ATE407927T1 (pl)
AU (1) AU2005307744C1 (pl)
BR (1) BRPI0518446A2 (pl)
CA (1) CA2588513C (pl)
CR (1) CR9098A (pl)
CY (1) CY1108508T1 (pl)
DE (1) DE602005009748D1 (pl)
DK (1) DK1833799T3 (pl)
EA (1) EA011935B1 (pl)
ES (1) ES2314750T3 (pl)
GT (1) GT200500336A (pl)
HK (1) HK1102818A1 (pl)
HN (1) HN2005032627A (pl)
HR (1) HRP20080592T3 (pl)
IL (1) IL182945A (pl)
MA (1) MA29081B1 (pl)
MX (1) MX2007005959A (pl)
MY (1) MY147684A (pl)
NI (1) NI200700127A (pl)
NO (1) NO340656B1 (pl)
NZ (1) NZ554817A (pl)
PE (1) PE20061130A1 (pl)
PL (1) PL1833799T3 (pl)
PT (1) PT1833799E (pl)
RS (1) RS50698B (pl)
SA (1) SA05260357B1 (pl)
SI (1) SI1833799T1 (pl)
SV (1) SV2008002307A (pl)
TN (1) TNSN07188A1 (pl)
TW (2) TWI409062B (pl)
WO (1) WO2006055734A2 (pl)

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