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PL1625164T3 - Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46 - Google Patents

Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46

Info

Publication number
PL1625164T3
PL1625164T3 PL04732282T PL04732282T PL1625164T3 PL 1625164 T3 PL1625164 T3 PL 1625164T3 PL 04732282 T PL04732282 T PL 04732282T PL 04732282 T PL04732282 T PL 04732282T PL 1625164 T3 PL1625164 T3 PL 1625164T3
Authority
PL
Poland
Prior art keywords
amino acids
monoclonal antibody
antibody binding
probnp
native probnp
Prior art date
Application number
PL04732282T
Other languages
English (en)
Inventor
Volker Klemt
Anneliese Borgya
Andreas Gallusser
Michael Grol
Klaus Hallermayer
Christoph Seidel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33427054&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1625164(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL1625164T3 publication Critical patent/PL1625164T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL04732282T 2003-05-12 2004-05-12 Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46 PL1625164T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03010591 2003-05-12
PCT/EP2004/005092 WO2004099253A1 (en) 2003-05-12 2004-05-12 Method of detecting probnp with a monoclonal antibody binding to the amino acid 41-46
EP04732282A EP1625164B1 (en) 2003-05-12 2004-05-12 Method of detecting probnp with a monoclonal antibody binding to the amino acids 42-46

Publications (1)

Publication Number Publication Date
PL1625164T3 true PL1625164T3 (pl) 2011-12-30

Family

ID=33427054

Family Applications (3)

Application Number Title Priority Date Filing Date
PL10172014T PL2256132T3 (pl) 2003-05-12 2004-05-12 Sposób wykrywania proBNP z zastosowaniem przeciwciała monoklonalnego
PL04732282T PL1625164T3 (pl) 2003-05-12 2004-05-12 Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46
PL04732278T PL1625163T3 (pl) 2003-05-12 2004-05-12 Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL10172014T PL2256132T3 (pl) 2003-05-12 2004-05-12 Sposób wykrywania proBNP z zastosowaniem przeciwciała monoklonalnego

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL04732278T PL1625163T3 (pl) 2003-05-12 2004-05-12 Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43

Country Status (15)

Country Link
US (4) US7264938B2 (pl)
EP (4) EP1625164B1 (pl)
JP (4) JP4430066B2 (pl)
KR (2) KR100857752B1 (pl)
CN (3) CN101967190A (pl)
AT (2) ATE517124T1 (pl)
AU (1) AU2004235974B2 (pl)
BR (1) BRPI0410261B8 (pl)
CA (2) CA2522378C (pl)
DK (3) DK2256132T3 (pl)
ES (3) ES2369008T3 (pl)
HU (1) HUE025169T2 (pl)
MX (1) MXPA05011826A (pl)
PL (3) PL2256132T3 (pl)
WO (2) WO2004099253A1 (pl)

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FR2843396B1 (fr) * 2002-08-07 2005-04-15 Bio Rad Pasteur Anticorps specifiques pour le diagnostic de l'insuffisance cardiaque
ES2369008T3 (es) * 2003-05-12 2011-11-24 F. Hoffmann-La Roche Ag Método para detectar probnp con un anticuerpo monoclonal que fija los aminoácidos 42-46.
WO2004105575A2 (en) * 2003-05-29 2004-12-09 Trustee Of Darmouth College A method for detecting cardiac ischemia via changes in b-natriuretic peptide levels
DE10355731A1 (de) 2003-11-28 2005-06-30 Roche Diagnostics Gmbh Analytischer Sandwichtest zur Bestimmung von NT-proBNP
DE602005001299T2 (de) * 2004-07-07 2008-02-07 Roche Diagnostics Gmbh Kombinationen von Markern zum Nachweis von typ 1 und 2 Diabetes
AT500800B1 (de) * 2004-09-08 2008-07-15 Biomedica Medizinprodukte Gmbh Verfahren zur bestimmung von probnp
JP2010517023A (ja) 2007-01-25 2010-05-20 エフ．ホフマン−ラ ロシュ アーゲー 心不全の評価におけるｉｇｆｂｐ−７の使用
KR100836322B1 (ko) * 2007-08-31 2008-06-09 현대자동차주식회사 차량용 흡음재 제작장치 및 방법
US9482677B2 (en) 2008-02-27 2016-11-01 Scios Inc. Method, composition and device for sampling natriuretic peptides in a biological fluid
CA2722485C (en) 2008-04-30 2018-02-13 F. Hoffmann-La Roche Ag Use of sfrp-3 in the assessment of heart failure
JP5592487B2 (ja) 2009-07-27 2014-09-17 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 心不全の評価におけるミメカンの使用
BR112012011230A2 (pt) * 2009-11-13 2016-04-05 Bg Medicine Inc fatores de risco e previsão de infarto do miocárdio
AU2011285694B2 (en) 2010-08-04 2014-12-18 Idexx Laboratories, Inc. Detection of degradation products of canine NT-proBNP
EP2715353B1 (en) 2011-05-31 2016-08-24 IDEXX Laboratories, Inc. DETECTION OF DEGRADATION PRODUCTS OF FELINE NT-proBNP
JP6119607B2 (ja) * 2011-09-20 2017-04-26 コニカミノルタ株式会社 検体希釈用液、それを用いたキットおよび蛍光測定方法
US20140273273A1 (en) 2012-11-01 2014-09-18 Christie Mitchell Ballantyne Biomarkers to improve prediction of heart failure risk
CN103304665A (zh) * 2013-05-21 2013-09-18 上海贝西生物科技有限公司 一种抗氨基末端脑利钠肽前体单克隆抗体及其应用
WO2016056664A1 (ja) * 2014-10-10 2016-04-14 松森　昭 心不全患者の検出方法、心疾患の識別方法、心不全の検査試薬、心不全の検査キット、心不全を検出するための装置及び心不全を検出するためのプログラム
EP3360570A1 (en) 2017-02-13 2018-08-15 Roche Diagnostics GmbH Antibodies recognizing genetic variants
JP7203034B2 (ja) * 2017-10-02 2023-01-12 大塚製薬株式会社 アナライトの検出方法
WO2019198822A1 (ja) * 2018-04-13 2019-10-17 共立製薬株式会社 心不全検出方法、心不全検出用器具、サンドイッチ免疫学的測定方法、並びに抗体の組合せ
CN108752480B (zh) * 2018-05-30 2022-03-29 中元汇吉生物技术股份有限公司 一种免疫原组合物、其制备方法及其用途
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US11931207B2 (en) 2018-12-11 2024-03-19 Eko.Ai Pte. Ltd. Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device
US12001939B2 (en) 2018-12-11 2024-06-04 Eko.Ai Pte. Ltd. Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
US12322100B2 (en) 2018-12-11 2025-06-03 Eko.Ai Pte. Ltd. Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity
CN111487222B (zh) * 2019-01-28 2023-11-14 上海乐合生物科技有限公司 一种检测bnp的spr芯片的制备方法
CN114207444A (zh) 2019-08-13 2022-03-18 挪威金田有限公司 用于NT-proBNP定量的高灵敏度颗粒增强测定
US20230366894A1 (en) * 2020-09-30 2023-11-16 Roche Diagnostics Operations, Inc. Circulating total-nt-probnp (glycosylated and unglycosylated nt-probnp) and its ratio with nt-probnp (unglycosylated nt-probnp) in the assessment of atrial fibrillation
CN112964885B (zh) * 2021-02-20 2022-11-11 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
CN112986586A (zh) * 2021-02-20 2021-06-18 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
JP2024538607A (ja) 2021-10-01 2024-10-23 ゲンティアン アクティーゼルスカブ サンプル中のｎ末端プロホルモンｂｎｐ（ｎｔ－プロｂｎｐ）の濃度を測定するための新規方法
JP2025508481A (ja) 2022-03-18 2025-03-26 エフ． ホフマン－ラ ロシュ アーゲー ２型対１型の急性心筋梗塞の早期識別のためのトロポニンマーカーの組合せ
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Also Published As

Publication number Publication date
EP1625164B1 (en) 2011-07-20
ES2548327T3 (es) 2015-10-15
KR20080011467A (ko) 2008-02-04
CN100497393C (zh) 2009-06-10
JP2007525427A (ja) 2007-09-06
US20070117156A1 (en) 2007-05-24
US7811770B2 (en) 2010-10-12
MXPA05011826A (es) 2006-01-26
JP2010011860A (ja) 2010-01-21
CA2522747C (en) 2012-08-14
US7807380B2 (en) 2010-10-05
JP4834136B2 (ja) 2011-12-14
EP1625163B8 (en) 2011-11-02
JP5649631B2 (ja) 2015-01-07
WO2004099252A1 (en) 2004-11-18
JP2007535470A (ja) 2007-12-06
EP1625163B1 (en) 2011-08-31
JP4430066B2 (ja) 2010-03-10
CN1832964A (zh) 2006-09-13
JP5128125B2 (ja) 2013-01-23
EP2256132B1 (en) 2015-04-01
EP2256132A1 (en) 2010-12-01
ATE522546T1 (de) 2011-09-15
DK1625163T3 (da) 2011-12-05
BRPI0410261B8 (pt) 2021-07-27
AU2004235974A1 (en) 2004-11-18
HUE025169T2 (en) 2016-02-29
US20060110776A1 (en) 2006-05-25
CA2522378A1 (en) 2004-11-18
US20070099241A1 (en) 2007-05-03
CN1784425A (zh) 2006-06-07
CA2522378C (en) 2011-03-29
PL1625163T3 (pl) 2012-01-31
HK1097855A1 (zh) 2007-07-06
BRPI0410261A (pt) 2006-05-16
US7264939B2 (en) 2007-09-04
ATE517124T1 (de) 2011-08-15
ES2369008T3 (es) 2011-11-24
EP2949669A1 (en) 2015-12-02
ES2372282T3 (es) 2012-01-18
KR20060003905A (ko) 2006-01-11
CA2522747A1 (en) 2004-11-18
JP2013018784A (ja) 2013-01-31
US7264938B2 (en) 2007-09-04
BRPI0410261B1 (pt) 2020-03-10
EP1625163A1 (en) 2006-02-15
AU2004235974B2 (en) 2008-02-14
WO2004099253A1 (en) 2004-11-18
KR100857752B1 (ko) 2008-09-11
US20060110775A1 (en) 2006-05-25
DK2256132T3 (en) 2015-07-13
EP1625164A1 (en) 2006-02-15
PL2256132T3 (pl) 2016-08-31
CN101967190A (zh) 2011-02-09
DK1625164T3 (da) 2011-10-31

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